Abstract：
:During the last 2 decades there has been a substantial increase in illicit drug consumption in North America. It has been repeatedly shown that the personal history of drug use is far from being accurate. Fearing legal consequences and embarrassment of admitted illicit substance use, most users tend to deny or, to under-report illicit drug consumption. These facts have stressed an urgent need for a biological marker which does not lose its sensitivity within a few days after the end of exposure and which may yield a cumulative reflection of long term exposure to illicit drugs. Hair analysis has emerged as such a marker. A variety of illicit and medicinal compounds have been shown to be incorporated into hair including trace metals, barbiturates, amphetamines, opiates, phencyclidine, cocaine, nicotine and cannabis. Hair analysis for drugs of abuse provides long-term information on an individual's drug use; its window of detection is limited only by the length of the hair and typically, ranges from a week to several months. After establishing and validating several hair tests during the last decade, we have analyzed over 1000 hair samples for different drugs of abuse. We used RIA for screening and GC-MS for confirmation of positive results. The aim of this report is to illustrate the diagnostic usefulness of hair testing in different age groups (newborns, children, adults) and circumstances: (criminal cases, athletes, child custody cases, etc.).
journal_name
Forensic Sci Intjournal_title
Forensic science internationalauthors
Klein J,Karaskov T,Koren Gdoi
10.1016/s0379-0738(99)00171-1keywords:
subject
Has Abstractpub_date
2000-01-10 00:00:00pages
281-8issue
1-3eissn
0379-0738issn
1872-6283pii
S0379-0738(99)00171-1journal_volume
107pub_type
杂志文章abstract：:Three novel fluorescent dyes were evaluated for the detection of latent fingermarks on different types and colors of adhesive tapes. Compared with the conventional reagents used to reveal latent fingermarks on these surfaces, these new fluorescent dyes have many advantages. They are highly selective to fingermarks, re...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2016.03.053
更新日期：2016-06-01 00:00:00
abstract：:Morphometric cranial variation among Spanish samples was compared to a 19th century Portuguese sample using both traditional and three-dimensional approaches. The Spanish samples included the regional 19th century Oloriz collection and the local 16-17th century Villanubla and Vallolid sample from northwestern Spain. R...
journal_title：Forensic science international
pub_type： 历史文章,杂志文章
doi：10.1016/j.forsciint.2011.01.003
更新日期：2011-03-20 00:00:00
abstract：:Conclusive evidence was obtained in this study that immunoelectrophoresis could be used in the identification of blood-stains in two particular cases: for diagnosis or approach to diagnosis of the age of a blood-stain, and for diagnosis of the human origin of a blood-stain that had been treated with petroleum products...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/0379-0738(78)90025-7
更新日期：1978-09-01 00:00:00
abstract：:Allele frequencies, forensic parameters for the 11 STR loci (TH01, TPOX, CSF1PO, D13S317, D7S820, D16S539, VWA, FESFPS, F13A01, F13B and LPL) were determined in a sample of 140-1262 unrelated adults from the Upper Silesia region (Poland). Comparison of allele frequencies for examined STR loci between the Upper Silesia...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2006.01.011
更新日期：2007-05-03 00:00:00
abstract：:The increase in the use of photographs on individual identification credentials such as driving licences, credit cards, security passes and passports has led, for the purpose of criminal activities, to the falsification of genuine documents bearing photographs of the perpetrating criminal. These photographs may be use...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/s0379-0738(00)00290-5
更新日期：2000-11-13 00:00:00
abstract：:Two rates of carbon dioxide flow into the termination chamber were applied for the euthanasia of rats. The classical phases of asphyxia were observed in both groups of animals although their course was prolonged in rats exposed to the lower gas flow. The haemorrhages were assessed histologically in the following struc...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/s0379-0738(01)00591-6
更新日期：2001-12-27 00:00:00
abstract：:This research presents a new software, "Fragmento", for accurate analyses of fragmentary human skeletal remains and facilitation of three-dimensional (3D) fragmentary matching and full bone reconstruction. The framework utilizes the power of statistical bone atlases to create 3D templates for bone matching and to inte...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2017.03.017
更新日期：2017-06-01 00:00:00
abstract：:The aim of the study was to improve the objectivity of X-ray image comparison for the identification of unknown dead individuals. CT-data were collected for 30 macerated skulls. An already presented computer program which uses CT data to establish virtual X-ray images was used to obtain X-rays with different beam angu...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/s0379-0738(00)00452-7
更新日期：2001-03-01 00:00:00
abstract：:With the constantly increasing sensitivity and robustness of liquid chromatography-mass spectrometry-based instruments combined with enhanced reproducibility as well as mass accuracy and resolution, LC-MS(/MS) has become an integral part of sports drug testing programs particularly concerning the detection of peptide ...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2011.06.015
更新日期：2011-12-10 00:00:00
abstract：:Cannabis is the one of the most frequently detected drug in workplace drug testing and in cases of driving under influence of drugs, and there is a greater demand for sensitive, rapid and reliable methods for confirming the presence of this drug in biological samples. This paper describes an LC-MS-MS procedure for dir...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2010.05.004
更新日期：2011-01-30 00:00:00
abstract：:The lungs of deep smokers contain large numbers of alveolar macrophages with pigment granules in the cytoplasma that are demonstrable by means of fat stains and a distinct green-yellow inherent fluorescence at a wave length range of 350-450 nm. Systematic examinations to test the eluting effect of different solvents o...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/0379-0738(86)90068-x
更新日期：1986-05-01 00:00:00
abstract：:A minisatellite probe, MZ 1.3, detecting hypervariable fragment patterns was isolated from a human genomic library. A repetitive sequence of 27 bp length was identified which is contained in the probe approx. 40 times. The MZ 1.3 repeat shows variable homology of 53-73% to the repetitive sequence of the protein III ge...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/0379-0738(90)90252-t
更新日期：1990-02-01 00:00:00
abstract：:Blotter papers laced with lysergic acid diethylamide (LSD) have been abused traditionally for their hallucinogenic properties. In recent years, new psychedelic phenethylamines such as 2,5-dimethoxyphenethylamines (2C) and their N-benzylhydroxy (25-NBOH) and N-2-methoxybenzyl derivatives (25-NBOMe) have emerged in the ...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2019.05.036
更新日期：2019-08-01 00:00:00
abstract：:1,2-Indanedione treated fingerprints deposited on two substrates (thermal and carbonless paper) were swabbed and tested to determine the effect of the chemical on PCR-STR DNA typing. Samples from 10 post-treatment intervals were analyzed. Two extraction methods, Chelex and Qiamp, were used to determine the effect of e...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2006.06.071
更新日期：2007-05-24 00:00:00
abstract：:Munchausen syndrome by proxy (MSBP) is a special form of child abuse in which an adult repeatedly produces symptoms of illness in a person under his/her care. In most cases the perpetrators are mothers who repeatedly and in different ways produce or feign symptoms of illness in their children in order to obtain medica...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2003.07.007
更新日期：2003-11-26 00:00:00
abstract：:Leukotriene B4 (LTB4) in skin samples from seven forensic cases was detected by HPLC to distinguish their antemortem or postmortem origin. In total, there were thirteen antemortem and seven postmortem specimens. The results showed that LTB4 was found in all antemortem wound specimens which were either fresh, or refrig...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/0379-0738(96)01938-x
更新日期：1996-07-31 00:00:00
abstract：:Trends in forensic toxicology show the advancement of rapid and sensitive analytical methods for qualitative and quantitative analysis of drugs of abuse. However, forensic toxicologists are continuously faced with the challenges of identifying and quantifying drug blood concentration while simultaneously struggling wi...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2019.03.048
更新日期：2019-07-01 00:00:00
abstract：:Y-chromosomal variation at five biallelic markers (Tat, YAP, 12f2, SRY(10831) and 92R7) and nine multiallelic short tandem repeat (STR) loci (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385I/II and DYS388) in a Norwegian population sample are presented. The material consists of 1766 unrelated males of...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2005.11.009
更新日期：2006-12-01 00:00:00
abstract：:The objective of the study is to better understand how blunt projectile ballistic parameters and material properties influence the events leading to injuries. The present work focuses on lateral thoracic impacts and follows an experimental approach. The projectiles are made with a soft foam nose assembled with a rigid...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2015.04.004
更新日期：2015-07-01 00:00:00
abstract：:In this paper, we describe an acetylating method for fast synthesis of heroin from morphine in the presence of 4-dimethylaminopyridine (4-DMAP) as a catalyst. In the reaction which led to heroin formation, the morphine base was subjected to a solution made up of 4-DMAP (catalyst), methylene chloride (solvent) and acet...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/s0379-0738(02)00291-8
更新日期：2002-10-09 00:00:00
abstract：:Cyanoacrylate fuming, rhodamine 6G staining and 532 nm laser light visualization were used to reveal a thirty-year-old fingermark on a plastic bag discovered at a double homicide scene. ...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2019.04.025
更新日期：2019-07-01 00:00:00
abstract：:In the case of disasters or crime scenes, forensic anthropometric methods have been utilized as a reliable way to quickly confirm the identification of victims using only a few parts of the body. A total of 321 measurement data (from 167 males and 154 females) were analyzed to investigate the suitability of detailed h...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2015.10.014
更新日期：2015-12-01 00:00:00
abstract：:We study the transient indirect effect of a rifle bullet on bone in the gelatin-bone composite target experimentally and computationally. The process of a 56 type 7.62-mm rifle bullet penetrating the composite target has been simulated using numerical method. The experiment provided the criteria for verifying the corr...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2015.10.032
更新日期：2015-12-01 00:00:00
abstract：:In this paper, a high performance liquid chromatographic method with fluorescence detection (HPLC-FL) for the determination of fenfluramine (Fen) and norfenfluramine (Norf) in human hair as biomarker metabolites of N-nitrosofenfluramine (N-Fen) is described. Washed and cut hair segments were extracted by ultrasonicati...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2004.03.018
更新日期：2004-11-10 00:00:00
abstract：BACKGROUND:Studies testing the Willems method of age estimation with gender-specific scores on different population groups have reported consistently more accurate results over other methods. Not enough is known about the validity of Willems non-gender specific scores. AIM:The present study aimed to compare the accura...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2016.05.012
更新日期：2016-09-01 00:00:00
abstract：:The value of complex analyses of body injuries and clothing has been proven by practice. The purpose of presented study is to discuss what additional information can be obtained during investigations of clothes in the area of injury. A case study, in which results of visual and stereomicroscopic morphological analysis...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2004.09.023
更新日期：2004-12-02 00:00:00
abstract：:The comparison of two or more samples of liquid gasoline (petrol) to establish a common origin is a difficult problem in the forensic investigation of arsons and suspicious fires. A total of 35 randomly collected samples of unevaporated gasoline, covering three different grades (regular unleaded, premium unleaded and ...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/s0379-0738(03)00081-1
更新日期：2003-06-24 00:00:00
abstract：:Pubic hair is often analyzed as an alternative to scalp hair to prove previous drug use. However, urine is a potential source of external contamination. In the present study, the concentrations of methamphetamine (MA) and amphetamine (AP) in both scalp and pubic hair from illegal MA users were compared. Furthermore, i...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2010.06.009
更新日期：2011-03-20 00:00:00
abstract：:We describe two cases of human consumption of seeds from Argyreia nervosa (Hawaiian Baby Woodrose), which resulted in one fatality due to falling from a building and one surviving witness. The principal psychoactive constituent of the seeds, lysergamide (LSA), was recovered from blood and urine samples by mixed-mode c...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2009.11.017
更新日期：2010-04-15 00:00:00
abstract：:A large number of passerine birds, mainly greenfinches, were found dead or dying in a hedgerow close to a field of onions recently sprayed with sodium monochloroacetate (SMCA). An analytical method is described for isolating monochloroacetic acid from bird tissues, as its potassium salt, by ion exchange chromatography...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/0379-0738(92)90075-8
更新日期：1992-04-01 00:00:00
