Parallel differentiation of embryonic stem cells into different cell types by a single gene-based differentiation system.

abstract：:The online-ahead-of print e-pub version of the article entitled, Bone Mesenchymal Stem Cell-Conditioned Medium Regulates the Differentiation of Neural Stem Cells Via Notch Pathway Activation, by Li H-M, Tong Y, Xia X, Huang J, Song P-W, Zhang R-J, Shen C-L, utilizing the DOI number 10.1089/cell.2018.0042 is being offi...

journal_title：Cellular reprogramming

authors： Li HM,Tong Y,Xia X,Huang J,Song PW,Zhang RJ,Shen CL

更新日期：2018-12-27 00:00:00

abstract：:Recent work has shown that mouse and human fibroblasts can be reprogrammed to cardiomyocyte-like cells with a combination of transcription factors. Current research has focused on improving the efficiency and mechanisms for fibroblast reprogramming. Previously, it has been reported that hypoxia enhances fibroblast cel...

journal_title：Cellular reprogramming

authors： Wang Y,Shi S,Liu H,Meng L

更新日期：2016-02-01 00:00:00

abstract：:The development of embryos produced by somatic cell nuclear transfer (SCNT) using vitrified oocytes as cytoplast recipients has been reported in cattle but not in sheep. This study investigated the parthenogenetic development of ovine oocytes vitrified and thawed at the germinal vesicle (GV) stage, matured in vitro, a...

journal_title：Cellular reprogramming

authors： Moawad AR,Choi I,Zhu J,Campbell KH

更新日期：2011-08-01 00:00:00

abstract：:Previous studies have shown that the time interval between fusion and activation (FA interval) play an important role in nuclear remodeling and in vitro development of somatic cell nuclear transfer (SCNT) embryos. However, the effects of FA interval on the epigenetic reprogramming and in vivo developmental competence ...

journal_title：Cellular reprogramming

authors： Liu J,Wang Y,Su J,Wang L,Li R,Li Q,Wu Y,Hua S,Quan F,Guo Z,Zhang Y

更新日期：2013-04-01 00:00:00

abstract：:The less differentiated the donor cells are used in nuclear transfer (NT), the more easily are they reprogrammed by the recipient cytoplasm. In this context, mesenchymal stem cells (MSCs) appear as an alternative to donor nuclei for NT. The amniotic fluid and adipose tissue are sources of MSCs that have not been teste...

journal_title：Cellular reprogramming

authors： da Silva CG,Martins CF,Cardoso TC,da Cunha ER,Bessler HC,Martins GH,Pivato I,Báo SN

更新日期：2016-04-01 00:00:00

abstract：:In this study, we found that the measles virus (MV) can infect human-induced pluripotent stem cells (hiPSCs). Wild-type MV strains generally use human signaling lymphocyte activation molecule (SLAM; CD150) as a cellular receptor, while vaccine strains such as the Edmonston strain can use both CD150 and CD46 as recepto...

journal_title：Cellular reprogramming

authors： Naaman H,Rabinski T,Yizhak A,Mizrahi S,Avni YS,Taube R,Rager B,Weinstein Y,Rall G,Gopas J,Ofir R

更新日期：2018-02-01 00:00:00

abstract：:Despite widespread application of intracytoplasmic sperm injection (ICSI) in human-assisted reproductive techniques (ART), the efficiency of this method is still far from satisfactory in livestock, particularly in the bovine species with its unique sperm condensation. On the basis of the natural chemical structure of ...

journal_title：Cellular reprogramming

authors： Sekhavati MH,Shadanloo F,Hosseini MS,Tahmoorespur M,Nasiri MR,Hajian M,Nasr-Esfahani MH

更新日期：2012-08-01 00:00:00

abstract：:Adult cardiomyocytes have little ability to regenerate, thus cardiac regeneration therapy represents a potential method for treating severe heart failure. Human amniotic mesenchymal cells (hAMCs) have the potential to be a useful cell source for cardiac regeneration therapy. We attempted to isolate stem cells from hAM...

journal_title：Cellular reprogramming

authors： Otaka S,Nagura S,Koike C,Okabe M,Yoshida T,Fathy M,Yanagi K,Misaki T,Nikaido T

更新日期：2013-02-01 00:00:00

abstract：:Buffalo embryos were produced by hand-made cloning using skin fibroblasts from male and female buffaloes (n = 4 each) as donor cells for examining the effect of sex. Although the rate of blastocyst formation (43.8% ± 1.31% vs. 42.2% ± 1.22%) was similar, the total cell number (333 ± 10.4 vs. 270 ± 10.9) was higher (p ...

journal_title：Cellular reprogramming

authors： Sandhu A,Mohapatra SK,Agrawal H,Singh MK,Palta P,Singla SK,Chauhan MS,Manik RS

更新日期：2016-10-01 00:00:00

abstract：:Male germline stem cells (mGSCs) are stem cells present in male testis responsible for spermatogenesis during their whole life. Studies have shown that mGSCs can be derived in vitro and resemble embryonic stem cells (ESCs) properties both in the mouse and humans. However, little is know about these cells in domestic a...

journal_title：Cellular reprogramming

authors： Hua J,Zhu H,Pan S,Liu C,Sun J,Ma X,Dong W,Liu W,Li W

更新日期：2011-04-01 00:00:00

abstract：:A simple, rapid, efficient, and specialized culture system was successfully developed in this study to induce human embryonic stem cells into dopaminergic neurons in vitro. It only took 5 days to generate quickly and directly a large number of homogeneous neural stem cell (NSC) spheres by the introduction of small mol...

journal_title：Cellular reprogramming

authors： Qiu X,Liu Y,Xiao X,He J,Zhang H,Li Y

更新日期：2019-12-01 00:00:00

abstract：:Although numerous mammalian species have been successfully cloned by somatic cell nuclear transfer (SCNT), little is known about gene expression of cloned pigs by SCNT. In the present study, expression profiles of 1-month-old cloned pigs generated from fetal fibroblasts (n = 5) were compared to those of age-matched co...

journal_title：Cellular reprogramming

authors： Park J,Lai L,Samuel M,Wax D,Bruno RS,French R,Prather RS,Yang X,Tian XC

更新日期：2011-06-01 00:00:00

abstract：:In contrast to adult stem cells, induced pluripotent stem cells (iPSCs) can be grown robustly in vitro and differentiated into virtually any tissue, thus providing an attractive alternative for biomedical applications. Although iPSC technology is already being used in human biomedicine, its potential in animal product...

journal_title：Cellular reprogramming

authors： Cravero D,Martignani E,Miretti S,Accornero P,Pauciullo A,Sharma R,Donadeu FX,Baratta M

更新日期：2015-06-01 00:00:00

abstract：:Edaravone can induce differentiation of bone marrow mesenchymal stem cells (BMSCs) into neuron-like cells and replace lost cells by transplanting neuron-like cells to repair spinal cord injury (SCI). In this study, BMSCs were derived from the bone marrow of male Wistar rats (4 weeks old) through density gradient centr...

journal_title：Cellular reprogramming

authors： Li Y,Liu L,Yu Z,Yu Y,Sun B,Xiao C,Luo S,Li L

更新日期：2021-01-05 00:00:00

abstract：:Somatic cell nuclear transfer (SCNT), commonly referred to as cloning, results in the generation of offspring that, except for mitochondrial DNA, are genetically identical to the nuclear donor. We previously used a genetically modified bovine cell line as the donor for SCNT and obtained a calf, named Daisy, that was b...

journal_title：Cellular reprogramming

authors： Wagner S,Cullum A,Wells DN,Laible G

更新日期：2017-12-01 00:00:00

abstract：:Methyl-CpG-binding domain proteins (MBPs) connect DNA methylation and histone modification, which are the key changes of somatic cell reprogramming. Methyl-CpG-binding protein 2 (MeCP2) was the first discovered MBP that has been extensively studied in the neurodevelopmental disorder Rett syndrome. However, a role for ...

journal_title：Cellular reprogramming

authors： Wang ZD,Duan L,Zhang ZH,Song SH,Bai GY,Zhang N,Shen XH,Shen JL,Lei L

更新日期：2016-04-01 00:00:00

abstract：:The goals of the current study were to (1) improve culture conditions and (2) chemical passaging of bovine embryonic stem cell-like (bESC-like) cells. Specifically, the effects of human leukemia inhibitory factor (hLIF), two types of feeders, mouse embryonic fibroblast (MEF) and bovine embryonic fibroblast (BEF), as w...

journal_title：Cellular reprogramming

authors： Gong G,Roach ML,Jiang L,Yang X,Tian XC

更新日期：2010-04-01 00:00:00

abstract：:Cell Stemness can be achieved by various reprogramming techniques namely, somatic cell nuclear transfer, cell fusion, cell extracts, and introduction of transcription factors from which induced pluripotent stem cells (iPSCs) are obtained. iPSCs are valuable cell sources for drug screening and human disease modeling. A...

journal_title：Cellular reprogramming

authors： Mirahmadi M,Nakhaei-Rad S,Matin MM,Shahriyari M,Saeinasab M,Mahmoudi Z,Haghighitalab A,Mahdavi-Shahri N,Bahrami AR

更新日期：2016-10-01 00:00:00

abstract：:Adipose tissue-derived stromal cells (ADSCs) have been identified as a powerful stem cell source for cellular transplantation therapy. The dog is increasingly used as a model of human neurological disease; however, few studies have reported induction of canine ADSCs to neural lineages. We characterized canine ADSCs an...

journal_title：Cellular reprogramming

authors： Lim JH,Boozer L,Mariani CL,Piedrahita JA,Olby NJ

更新日期：2010-08-01 00:00:00

abstract：:Induced pluripotent stem cells (iPSCs) are promising candidates for the study of disease models as well as for tissue engineering purposes. Part of a strategy to develop safe reprogramming technique is reducing the number of exogenous reprogramming factors. Some cells types are more prone to reprogramming than others....

journal_title：Cellular reprogramming

authors： Ma MS,Czepiel M,Krause T,Schäfer KH,Boddeke E,Copray S

更新日期：2014-10-01 00:00:00

abstract：:Methyl-CpG-binding domain protein 3 (MBD3) is a core component of the nucleosome remodeling and deacetylase (NuRD) complex, which is crucial for pluripotent stem cell differentiation and embryonic development. MBD3 was shown to play important roles in transcription factor-induced somatic cell reprogramming. Expression...

journal_title：Cellular reprogramming

authors： Wang X,Shi J,Cai G,Zheng E,Liu D,Wu Z,Li Z

更新日期：2019-10-01 00:00:00

abstract：:Kunming (KM) mice are the most widely used strain in China. However, authentic embryonic stem cells (ESCs) from KM mice have never been available, and this hampers the genetic manipulation of this valuable mice strain. In this study, we show that KM ESCs can be efficiently derived and maintained in chemically defined ...

journal_title：Cellular reprogramming

authors： Peng X,Liu T,Yang B,Shi C,Sun Y,Jiang L,Jin H,Li L,Zhu H,Wu M,Qian Q

更新日期：2013-06-01 00:00:00

abstract：:Chickens are vitally important in numerous countries as a primary food source and a major component of economic development. Efforts have been made to produce transgenic birds through pluripotent stem cell [primordial germ cells and embryonic stem cells (ESCs)] approaches to create animals with improved traits, such a...

journal_title：Cellular reprogramming

authors： Yu P,Lu Y,Jordan BJ,Liu Y,Yang JY,Hutcheson JM,Ethridge CL,Mumaw JL,Kinder HA,Beckstead RB,Stice SL,West FD

更新日期：2014-10-01 00:00:00

abstract：:Induced pluripotent stem cells (iPSCs) are generated from somatic cells through ectopic expression of defined transcription factors. So far, many iPSC lines have been established in various species, including porcine. However, the molecular events during somatic cell reprogramming in pig are largely unknown. The aim o...

journal_title：Cellular reprogramming

authors： Cheng D,Li Z,Liu Y,Gao Y,Wang H

更新日期：2012-08-01 00:00:00

abstract：:The pig has been proposed as a relevant model for human obesity-induced inflammation, and cloning may improve the applicability of this model. We tested the assumptions that cloning would reduce interindividual variation in gene expression of innate immune factors and that their expression would remain unaffected by t...

journal_title：Cellular reprogramming

authors： Rødgaard T,Skovgaard K,Stagsted J,Heegaard PM

更新日期：2012-10-01 00:00:00

abstract：:The scope of this article is not to provide an exhaustive review of nuclear transfer research, because many authoritative reviews exist on the biological issues related to somatic and embryonic cell nuclear transfer. We shall instead provide an overview on the work done specifically on sheep and the value of this work...

journal_title：Cellular reprogramming

authors： Loi P,Czernik M,Zacchini F,Iuso D,Scapolo PA,Ptak G

更新日期：2013-10-01 00:00:00

abstract：:Induced pluripotent stem cells (iPSCs) remain a promising approach to target diseases with a loss of functional parenchyma. This technology comes with a number of concerns for clinical applications, including teratogenic potential and genomic instability. Here we focused on evaluating the safety of cross-species Senda...

journal_title：Cellular reprogramming

authors： Tarnawski L,Eugster E,DeCamp L,Jovinge S

更新日期：2019-04-01 00:00:00

abstract：:The present study compared the potential of porcine bone marrow mesenchymal stem cells (pBMSCs) at different passages as nuclear transfer (NT) donors and the developmental efficiency of NT embryos from donor cells transfected with/without Oct4 and Sox2. Early-passage pBMSCs showed higher proliferation and expression o...

journal_title：Cellular reprogramming

authors： Lee JH,Lee WJ,Jeon RH,Lee YM,Jang SJ,Lee SL,Jeon BG,Ock SA,King WA,Rho GJ

更新日期：2014-12-01 00:00:00

abstract：:Abstract Professor Keith Campbell's critical contribution to the discovery that a somatic cell from an adult animal can be fully reprogrammed by oocyte factors to form a cloned individual following nuclear transfer (NT)(Wilmut et al., 1997 ) overturned a dogma concerning the reversibility of cell fate that many scient...

journal_title：Cellular reprogramming

authors： Wells DN

更新日期：2013-10-01 00:00:00

abstract：:Factor-induced reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) as a powerful tool for regenerative medicine has gained wide attention in recent years. However, there are certain concerns regarding the efficiency of this reprogramming. Partially reprogrammed iPSCs (piPSCs) are stable cell lin...

journal_title：Cellular reprogramming

authors： Zhang L,Wang Y,Zhang Y,Wang L,Huang H

更新日期：2020-04-01 00:00:00