Measles Virus Persistent Infection of Human Induced Pluripotent Stem Cells.

abstract：:The generation of induced pluripotent stem cells (iPSCs) from somatic cells by expressing ectopic reprogramming transcriptional factors such as Oct3/4, Sox2, Klf4, c-Myc, and Nanog is one of the cutting-edge discoveries in stem cell and cancer research. This discovery has raised several safety issues regarding the use...

journal_title：Cellular reprogramming

authors： Ramakrishna S,Kim KS,Baek KH

更新日期：2014-04-01 00:00:00

abstract：:Demecolcine-assisted/induced enucleation has been used in nuclear transfer cloning procedures for many species, yet its mechanism of action remains unclear. Primarily because oocytoplasm protrusion induced by demecolcine is inhibited by the presence of cytochalasin, its use has had limited application. In this experim...

journal_title：Cellular reprogramming

authors： Meng Q,Wu X,Bunch TD,White K,Sessions BR,Davies CJ,Rickords L,Li GP

更新日期：2011-10-01 00:00:00

abstract：:The online-ahead-of print e-pub version of the article entitled, Bone Mesenchymal Stem Cell-Conditioned Medium Regulates the Differentiation of Neural Stem Cells Via Notch Pathway Activation, by Li H-M, Tong Y, Xia X, Huang J, Song P-W, Zhang R-J, Shen C-L, utilizing the DOI number 10.1089/cell.2018.0042 is being offi...

journal_title：Cellular reprogramming

authors： Li HM,Tong Y,Xia X,Huang J,Song PW,Zhang RJ,Shen CL

更新日期：2018-12-27 00:00:00

abstract：:The potential applications of a simplified method of somatic cell nuclear transfer (SCNT) that is improved in both efficiency and throughput is considerable. Technically, a major step of SCNT is to produce large pools of enucleated oocytes (cytoplasts) efficiently, a process that requires considerable micromanipulatio...

journal_title：Cellular reprogramming

authors： Hosseini SM,Hajian M,Moulavi F,Asgari V,Forouzanfar M,Nasr-Esfahani MH

更新日期：2013-02-01 00:00:00

abstract：:Methyl-CpG-binding domain protein 3 (MBD3) is a core component of the nucleosome remodeling and deacetylase (NuRD) complex, which is crucial for pluripotent stem cell differentiation and embryonic development. MBD3 was shown to play important roles in transcription factor-induced somatic cell reprogramming. Expression...

journal_title：Cellular reprogramming

authors： Wang X,Shi J,Cai G,Zheng E,Liu D,Wu Z,Li Z

更新日期：2019-10-01 00:00:00

abstract：:The less differentiated the donor cells are used in nuclear transfer (NT), the more easily are they reprogrammed by the recipient cytoplasm. In this context, mesenchymal stem cells (MSCs) appear as an alternative to donor nuclei for NT. The amniotic fluid and adipose tissue are sources of MSCs that have not been teste...

journal_title：Cellular reprogramming

authors： da Silva CG,Martins CF,Cardoso TC,da Cunha ER,Bessler HC,Martins GH,Pivato I,Báo SN

更新日期：2016-04-01 00:00:00

abstract：:Chickens are vitally important in numerous countries as a primary food source and a major component of economic development. Efforts have been made to produce transgenic birds through pluripotent stem cell [primordial germ cells and embryonic stem cells (ESCs)] approaches to create animals with improved traits, such a...

journal_title：Cellular reprogramming

authors： Yu P,Lu Y,Jordan BJ,Liu Y,Yang JY,Hutcheson JM,Ethridge CL,Mumaw JL,Kinder HA,Beckstead RB,Stice SL,West FD

更新日期：2014-10-01 00:00:00

abstract：:Animal cloning by nuclear transfer (NT) has made the production of transgenic animals using genetically modified donor cells possible and ensures the presence of the gene construct in the offspring. The identification of transgene insertion sites in donor cells before cloning may avoid the production of animals that c...

journal_title：Cellular reprogramming

authors： Bressan FF,Dos Santos Miranda M,Perecin F,De Bem TH,Pereira FT,Russo-Carbolante EM,Alves D,Strauss B,Bajgelman M,Krieger JE,Binelli M,Meirelles FV

更新日期：2011-02-01 00:00:00

abstract：:The development of embryos produced by somatic cell nuclear transfer (SCNT) using vitrified oocytes as cytoplast recipients has been reported in cattle but not in sheep. This study investigated the parthenogenetic development of ovine oocytes vitrified and thawed at the germinal vesicle (GV) stage, matured in vitro, a...

journal_title：Cellular reprogramming

authors： Moawad AR,Choi I,Zhu J,Campbell KH

更新日期：2011-08-01 00:00:00

abstract：:The pig has been proposed as a relevant model for human obesity-induced inflammation, and cloning may improve the applicability of this model. We tested the assumptions that cloning would reduce interindividual variation in gene expression of innate immune factors and that their expression would remain unaffected by t...

journal_title：Cellular reprogramming

authors： Rødgaard T,Skovgaard K,Stagsted J,Heegaard PM

更新日期：2012-10-01 00:00:00

abstract：:Despite widespread application of intracytoplasmic sperm injection (ICSI) in human-assisted reproductive techniques (ART), the efficiency of this method is still far from satisfactory in livestock, particularly in the bovine species with its unique sperm condensation. On the basis of the natural chemical structure of ...

journal_title：Cellular reprogramming

authors： Sekhavati MH,Shadanloo F,Hosseini MS,Tahmoorespur M,Nasiri MR,Hajian M,Nasr-Esfahani MH

更新日期：2012-08-01 00:00:00

abstract：:It has been demonstrated that several types of somatic stem cells have the remarkable capacity to differentiate into other types of tissues. However, the promise of keratinocyte stem cells seems slim for generating nonepidermal tissues. Using our recently developed acclimatization induction strategy, we demonstrate th...

journal_title：Cellular reprogramming

authors： Han W,Chen M,Li M,Wu Z,Zhao Y,Wang Y,Wang L,Yu L,Fu X

更新日期：2010-06-01 00:00:00

abstract：:Adult cardiomyocytes have little ability to regenerate, thus cardiac regeneration therapy represents a potential method for treating severe heart failure. Human amniotic mesenchymal cells (hAMCs) have the potential to be a useful cell source for cardiac regeneration therapy. We attempted to isolate stem cells from hAM...

journal_title：Cellular reprogramming

authors： Otaka S,Nagura S,Koike C,Okabe M,Yoshida T,Fathy M,Yanagi K,Misaki T,Nikaido T

更新日期：2013-02-01 00:00:00

abstract：:The rabbit is a useful animal model for regenerative medicine. We previously developed pluripotent rabbit embryonic stem cell (rbESC) lines using fresh embryos. We also successfully cryopreserved rabbit embryos by vitrification. In the present work, we combined these two technologies to derive rbESCs using vitrified-t...

journal_title：Cellular reprogramming

authors： Du F,Chen CH,Li Y,Hu Y,An LY,Yang L,Zhang J,Chen YE,Xu J

更新日期：2015-12-01 00:00:00

abstract：:Induced pluripotent stem cells (iPSCs) are generated from somatic cells through ectopic expression of defined transcription factors. So far, many iPSC lines have been established in various species, including porcine. However, the molecular events during somatic cell reprogramming in pig are largely unknown. The aim o...

journal_title：Cellular reprogramming

authors： Cheng D,Li Z,Liu Y,Gao Y,Wang H

更新日期：2012-08-01 00:00:00

abstract：:Induced pluripotent stem cells (iPSCs) play an important role in cell replacement therapy. Several studies have shown that keratinocytes are promising reprogrammed cells. We easily and efficiently enriched epidermal stem cells by attaching them for a limited time in culture dishes. Individual epidermal cells enriched ...

journal_title：Cellular reprogramming

authors： Yang YH,Zhang RZ,Cheng S,Xu B,Tian T,Shi HX,Xiao L,Chen RH

更新日期：2018-12-01 00:00:00

abstract：:The potential clinical applications of hematopoietic stem cells (HSCs) derived from human pluripotent stem cells (hPSCs) are limited by the difficulty of recapitulating embryoid hematopoiesis and by the unknown differentiation potential of hPSC lines. To evaluate their hematopoietic developmental potential, available ...

journal_title：Cellular reprogramming

authors： Tesarova L,Simara P,Stejskal S,Koutna I

更新日期：2017-08-01 00:00:00

abstract：:Adipose tissue-derived stromal cells (ADSCs) have been identified as a powerful stem cell source for cellular transplantation therapy. The dog is increasingly used as a model of human neurological disease; however, few studies have reported induction of canine ADSCs to neural lineages. We characterized canine ADSCs an...

journal_title：Cellular reprogramming

authors： Lim JH,Boozer L,Mariani CL,Piedrahita JA,Olby NJ

更新日期：2010-08-01 00:00:00

abstract：:Currently, cloning efficiency in pigs is very low. Donor cell type and number of cloned embryos transferred to an individual surrogate are two major factors that affect the successful rate of somatic cell nuclear transfer (SCNT) in pigs. This study aimed to compare the influence of different donor fibroblast cell type...

journal_title：Cellular reprogramming

authors： Li Z,Shi J,Liu D,Zhou R,Zeng H,Zhou X,Mai R,Zeng S,Luo L,Yu W,Zhang S,Wu Z

更新日期：2013-02-01 00:00:00

abstract：:The goals of the current study were to (1) improve culture conditions and (2) chemical passaging of bovine embryonic stem cell-like (bESC-like) cells. Specifically, the effects of human leukemia inhibitory factor (hLIF), two types of feeders, mouse embryonic fibroblast (MEF) and bovine embryonic fibroblast (BEF), as w...

journal_title：Cellular reprogramming

authors： Gong G,Roach ML,Jiang L,Yang X,Tian XC

更新日期：2010-04-01 00:00:00

abstract：:The scope of this article is not to provide an exhaustive review of nuclear transfer research, because many authoritative reviews exist on the biological issues related to somatic and embryonic cell nuclear transfer. We shall instead provide an overview on the work done specifically on sheep and the value of this work...

journal_title：Cellular reprogramming

authors： Loi P,Czernik M,Zacchini F,Iuso D,Scapolo PA,Ptak G

更新日期：2013-10-01 00:00:00

abstract：:Successful development of interspecies somatic cell nuclear transfer (iSCNT) embryos depends on compatibilities between ooplasmic and nuclear components. However, the mechanisms by which the compatibilities are regulated are still unknown. In this study, using mouse Oct4-green fluorescent protein (GFP) cells as donors...

journal_title：Cellular reprogramming

authors： Huang X,Song L,Zhan Z,Gu H,Feng H,Li Y

更新日期：2017-12-01 00:00:00

abstract：:Epithelial-to-mesenchymal transition (EMT) and endothelial-to-mesenchymal transition (EndMT) describe complex changes in progenitor lineage, cell morphology, and gene expression. Stimulated by environmental cues, these cellular transitions are essential for elements of embryonic development and can be pathologically d...

journal_title：Cellular reprogramming

authors： Schindeler A,Kolind M,Little DG

更新日期：2013-04-01 00:00:00

abstract：:Induced pluripotent stem cells (iPSCs) remain a promising approach to target diseases with a loss of functional parenchyma. This technology comes with a number of concerns for clinical applications, including teratogenic potential and genomic instability. Here we focused on evaluating the safety of cross-species Senda...

journal_title：Cellular reprogramming

authors： Tarnawski L,Eugster E,DeCamp L,Jovinge S

更新日期：2019-04-01 00:00:00

abstract：:Cell Stemness can be achieved by various reprogramming techniques namely, somatic cell nuclear transfer, cell fusion, cell extracts, and introduction of transcription factors from which induced pluripotent stem cells (iPSCs) are obtained. iPSCs are valuable cell sources for drug screening and human disease modeling. A...

journal_title：Cellular reprogramming

authors： Mirahmadi M,Nakhaei-Rad S,Matin MM,Shahriyari M,Saeinasab M,Mahmoudi Z,Haghighitalab A,Mahdavi-Shahri N,Bahrami AR

更新日期：2016-10-01 00:00:00

abstract：:In contrast to adult stem cells, induced pluripotent stem cells (iPSCs) can be grown robustly in vitro and differentiated into virtually any tissue, thus providing an attractive alternative for biomedical applications. Although iPSC technology is already being used in human biomedicine, its potential in animal product...

journal_title：Cellular reprogramming

authors： Cravero D,Martignani E,Miretti S,Accornero P,Pauciullo A,Sharma R,Donadeu FX,Baratta M

更新日期：2015-06-01 00:00:00

abstract：:Chicken embryonic stem cells (cESCs) isolated from the egg at the stage X hold great promise for cell therapy, tissue engineering, pharmaceutical, and biotechnological applications. They are considered to be pluripotent cells with the capacity to self-renewal and differentiate into specialized cells. However, long-ter...

journal_title：Cellular reprogramming

authors： Xiong C,Wang M,Ling W,Xie D,Chu X,Li Y,Huang Y,Li T,Otieno E,Qiu X,Xiao X

更新日期：2020-04-01 00:00:00

abstract：:Induced pluripotent stem cell (iPSC) technology has become an important tool for disease modeling. Insufficient data on the variability among iPSC lines derived from a single somatic parental cell line have in practice led to generation and analysis of several, usually three, iPSC sister lines from each parental cell ...

journal_title：Cellular reprogramming

authors： Schuster J,Halvardson J,Pilar Lorenzo L,Ameur A,Sobol M,Raykova D,Annerén G,Feuk L,Dahl N

更新日期：2015-10-01 00:00:00

abstract：:Previous studies have shown that the time interval between fusion and activation (FA interval) play an important role in nuclear remodeling and in vitro development of somatic cell nuclear transfer (SCNT) embryos. However, the effects of FA interval on the epigenetic reprogramming and in vivo developmental competence ...

journal_title：Cellular reprogramming

authors： Liu J,Wang Y,Su J,Wang L,Li R,Li Q,Wu Y,Hua S,Quan F,Guo Z,Zhang Y

更新日期：2013-04-01 00:00:00

abstract：:Transgenic animal producing technology has improved consistently over the last couple of decades. Among the available methods, somatic cell nuclear transfer (SCNT) technology was officially the most popular. However, SCNT has low efficiency and requires a highly skilled individual. Additionally, the allo-SCNT nuclear ...

journal_title：Cellular reprogramming

authors： Hwang JH,Kim SE,Gupta MK,Lee H

更新日期：2016-08-01 00:00:00