Abstract:
:Rat soleus muscle strips cultured for 24 h in medium 199 were well preserved in terms of electron microscopy; ATP and creatine phosphate concentrations; rates of glucose utilization, glycogen and protein synthesis, and effects of insulin thereon. Culture led to modest changes in fluid spaces and intracellular (K+); increased basal glucose utilization up to two-fold; had no effect on the maximum response to insulin; and had no effect on sensitivity to insulin except in the presence of adenosine deaminase. Thus in vitro neither denervation nor absence of insulin had any marked effects in 24 h to decrease responses to insulin.
journal_name
FEBS Lettjournal_title
FEBS lettersauthors
Stace PB,Marchington DR,Kerbey AL,Randle PJdoi
10.1016/0014-5793(90)81058-vsubject
Has Abstractpub_date
1990-10-29 00:00:00pages
91-4issue
1-2eissn
0014-5793issn
1873-3468pii
0014-5793(90)81058-Vjournal_volume
273pub_type
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