Abstract：
:Miocene hominoid material is very scarce and has previously only been reported as cranial fragments in the Old World. Here we describe a new specimen of Ouranopithecus macedoniensis, which consists of the right part of the face of an adult male with a portion of the frontal bone, a portion of the left part of the face and the maxilla with complete dentition except the right third molar. The characters of this specimen are not congruent with those of Sivapithecus and the pongids, but are more primitive and plesiomorphic for the recent hominid clade (Gorilla, Pan and Homo). The dental characters differ morphologically and metrically from those of the recent great apes and fit better with Australopithecus afarensis. Ouranopithecus now seems the best candidate forerunner of the Plio-pleistocene Homininae (Australopithecus and Homo). This specimen was discovered in September 1989, in the late Miocene deposits of central Macedonia (G.K., L. de B. and G.B.), and prepared by G.K. in Thessaloniki and G. Mouchelin in Poitiers. It comes from the new locality of Xirochori in the red sandstone of the Nea Messimbria formation. The fossil is the property of the University of Thessaloniki, Greece (catalogue number XIR-1).
journal_name
Naturejournal_title
Natureauthors
de Bonis L,Bouvrain G,Geraads D,Koufos Gdoi
10.1038/345712a0subject
Has Abstractpub_date
1990-06-21 00:00:00pages
712-4issue
6277eissn
0028-0836issn
1476-4687journal_volume
345pub_type
历史文章,杂志文章相关文献
NATURE文献大全abstract：:Protein design provides a rigorous test of our knowledge about proteins and allows the creation of novel enzymes for biotechnological applications. Whereas progress has been made in designing proteins that mimic native proteins structurally, it is more difficult to design functional proteins. In comparison to recent s...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/nature08620
更新日期：2009-12-24 00:00:00
abstract：:The determination of molecular masses from barometric sedimentation profiles, a main topic in ultracentrifugal analysis, is thought to be quantitatively correct for non-interacting particles. Whereas this expectation is justified for uncharged colloids or macromolecules at low volume fractions, early ultracentrifugati...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/nature02672
更新日期：2004-06-24 00:00:00
abstract：:The erosion of mountain belts controls their topographic and structural evolution and is the main source of sediment delivered to the oceans. Mountain erosion rates have been estimated from current relief and precipitation, but a more complete evaluation of the controls on erosion rates requires detailed measurements ...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/nature02150
更新日期：2003-12-11 00:00:00
abstract：:Immune-challenged vertebrate females transfer specific antibodies to their offspring, but this gratuitous immunity cannot operate in invertebrates. Here we show that constitutive immune defence is enhanced in sexual offspring of the bumble-bee Bombus terrestris L. when the parental colony is immune-challenged. Our fin...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/35107138
更新日期：2001-11-29 00:00:00
abstract：:Migration of cells in higher organisms is mediated by adhesion receptors, such as integrins, that link the cell to extracellular-matrix ligands, transmitting forces and signals necessary for locomotion. Whether cells will migrate or not on a given substratum, and also their speed, depends on several variables related ...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/385537a0
更新日期：1997-02-06 00:00:00
abstract：:Biodegradation of crude oil by bacterial activity--which has occurred in the majority of the Earth's oil reserves--is known to reduce greatly the quality of petroleum in reservoirs. For economically successful prospecting for oil, it is therefore important to understand the processes and conditions in geological forma...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/35082535
更新日期：2001-06-28 00:00:00
abstract：:The mechanism whereby eukaryotic pre-messenger RNAs are polyadenylated is unknown. Most models for polyadenylation invoke cleavage of precursor transcripts at the site of poly(A) addition followed by polymerization of A residues by poly(A) polymerase. Analysis of the sequences surrounding poly(A) addition sites has id...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/309179a0
更新日期：1984-05-10 00:00:00
abstract：:Distance determination in animals can be achieved by visual or non-visual cues. Weakly electric fish use active electrolocation for orientation in the dark. By perceiving self-produced electric signals with epidermal electroreceptors, fish can detect, locate and analyse nearby objects. Distance discrimination, however...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/27655
更新日期：1998-10-29 00:00:00
abstract：:The highly conserved protein gamma-tubulin is required for microtubule nucleation in vivo. When viewed in the electron microscope, a highly purified gamma-tubulin complex from Xenopus consisting of at least seven different proteins is seen to have an open ring structure. This complex acts as an active microtubule-nucl...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/378578a0
更新日期：1995-12-07 00:00:00
abstract：:Two large-scale yeast two-hybrid screens were undertaken to identify protein-protein interactions between full-length open reading frames predicted from the Saccharomyces cerevisiae genome sequence. In one approach, we constructed a protein array of about 6,000 yeast transformants, with each transformant expressing on...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/35001009
更新日期：2000-02-10 00:00:00
abstract：:Visual working memory provides an essential link between perception and higher cognitive functions, allowing for the active maintenance of information about stimuli no longer in view. Research suggests that sustained activity in higher-order prefrontal, parietal, inferotemporal and lateral occipital areas supports vis...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/nature07832
更新日期：2009-04-02 00:00:00
abstract：:It is generally thought that interspecific (lateral) transfer of genes is so extensive among bacteria that it is difficult, and perhaps impossible, to determine their phylogenetic relationships. Ambler and coworkers reflect this in their suggestion that the relationships seen among cytochrome c sequences of the Rhodos...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/283212a0
更新日期：1980-01-10 00:00:00
abstract：:The immunoglobulin superfamily is a group of proteins, each made of one or several domains sharing key structural features with either the variable (V) or the constant (C) immunoglobulin domains. It includes such functionally important members as the immunoglobulins themselves, major histocompatibility complex (MHC) c...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/328267a0
更新日期：1987-07-16 00:00:00
abstract：:Monocular lid suture during the sensitive period early in the life of a kitten disrupts normal development of inputs from the two eyes to the visual cortex, causing a decrease in the fraction of cortical cells responding to the deprived eye. Such an ocular dominance shift has been assumed to depend on patterned visual...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/324154a0
更新日期：1986-11-13 00:00:00
abstract：:All synaptically-based neuropsychological theories of learning postulate that there are changes resulting from neural activity which are long-lasting and confined to specific sets of synapses. In the past decade a form of synaptic strengthening known as long-term potentiation (LTP) has been found which results from hi...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/305717a0
更新日期：1983-10-20 00:00:00
abstract：:Glycogen synthase kinase-3beta (GSK-3beta) has integral roles in a variety of biological processes, including development, diabetes, and the progression of Alzheimer's disease. As such, a thorough understanding of GSK-3beta function will have a broad impact on human biology and therapeutics. Because GSK-3beta interact...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/nature05557
更新日期：2007-03-01 00:00:00
abstract：:Despite considerable global investment, only 60% of people who live with HIV currently receive antiretroviral therapy. The sustainability of current programmes remains unknown and key incidence rates are declining only modestly. Given the complexities and expenses associated with lifelong medication, developing an eff...
journal_title：Nature
pub_type： 杂志文章,评审
doi：10.1038/s41586-019-1841-8
更新日期：2019-12-01 00:00:00
abstract：:Spontaneous mutations are the source of genetic variation required for evolutionary change, and are therefore important for many aspects of evolutionary biology. For example, the divergence between taxa at neutrally evolving sites in the genome is proportional to the per nucleotide mutation rate, u (ref. 1), and this ...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/nature05388
更新日期：2007-01-04 00:00:00
abstract：:In sexually reproducing animals, a crucial step in zygote formation is the decondensation of the fertilizing sperm nucleus into a DNA replication-competent male pronucleus. Genome-wide nucleosome assembly on paternal DNA implies the replacement of sperm chromosomal proteins, such as protamines, by maternally provided ...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/nature04059
更新日期：2005-10-27 00:00:00
abstract：:In 1975-79, joint expeditions from Yale University and the Geological Survey of Pakistan (YGSP) recovered fossil lorisids in the Siwalik Group of Pakistan from four localities, spanning a period before 10 Myr ago to about 7 Myr ago. In three of the localities, only isolated teeth or fragments were found, whereas the f...
journal_title：Nature
pub_type： 历史文章,杂志文章
doi：10.1038/289585a0
更新日期：1981-02-12 00:00:00
abstract：:Evolutionary adaptation can be rapid and potentially help species counter stressful conditions or realize ecological opportunities arising from climate change. The challenges are to understand when evolution will occur and to identify potential evolutionary winners as well as losers, such as species lacking adaptive c...
journal_title：Nature
pub_type： 杂志文章,评审
doi：10.1038/nature09670
更新日期：2011-02-24 00:00:00
abstract：:Constructing agents with planning capabilities has long been one of the main challenges in the pursuit of artificial intelligence. Tree-based planning methods have enjoyed huge success in challenging domains, such as chess1 and Go2, where a perfect simulator is available. However, in real-world problems, the dynamics ...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/s41586-020-03051-4
更新日期：2020-12-01 00:00:00
abstract：:The recent discoveries of RNA interference and related RNA silencing pathways have revolutionized our understanding of gene regulation. RNA interference has been used as a research tool to control the expression of specific genes in numerous experimental organisms and has potential as a therapeutic strategy to reduce ...
journal_title：Nature
pub_type： 杂志文章,评审
doi：10.1038/nature02872
更新日期：2004-09-16 00:00:00
abstract：:Studies of galaxy surveys in the context of the cold dark matter paradigm have shown that the mass of the dark matter halo and the total stellar mass are coupled through a function that varies smoothly with mass. Their average ratio Mhalo/Mstars has a minimum of about 30 for galaxies with stellar masses near that of t...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/nature25767
更新日期：2018-03-28 00:00:00
abstract：:Peroxisomes are among the intracellular organelles of eukaryotic cells that contain specialized sets of enzymes with specific functions. Little is known of membranous components involved in assembly of the intracellular compartments. We isolated two peroxisome-deficient and mutually complementary, Chinese hamster ovar...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/350077a0
更新日期：1991-03-07 00:00:00
abstract：:The Wnt family of secreted glycoproteins mediate cell cell interactions during cell growth and differentiation in both embryos and adults. Canonical Wnt signalling by way of the beta-catenin pathway is transduced by two receptor families. Frizzled proteins and lipoprotein-receptor-related proteins 5 and 6 (LRP5/6) bin...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/nature756
更新日期：2002-06-06 00:00:00
abstract：:Magma intrusions and eruptions commonly produce abrupt changes in seismicity far from magma conduits that cannot be associated with the diffusion of pore fluids or heat. Such 'swarm' seismicity also migrates with time, and often exhibits a 'dog-bone'-shaped distribution. The largest earthquakes in swarms produce after...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/nature00997
更新日期：2002-09-05 00:00:00
abstract：:DNA methylation is highly dynamic during mammalian embryogenesis. It is broadly accepted that the paternal genome is actively depleted of 5-methylcytosine at fertilization, followed by passive loss that reaches a minimum at the blastocyst stage. However, this model is based on limited data, and so far no base-resoluti...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/nature10960
更新日期：2012-03-28 00:00:00
abstract：:Rab GTPases regulate all stages of membrane trafficking, including vesicle budding, cargo sorting, transport, tethering and fusion. In the inactive (GDP-bound) conformation, accessory factors facilitate the targeting of Rab GTPases to intracellular compartments. After nucleotide exchange to the active (GTP-bound) conf...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/nature03798
更新日期：2005-07-21 00:00:00
abstract：:Progress in the fabrication of nanometre-scale electronic devices is opening new opportunities to uncover deeper aspects of the Kondo effect--a characteristic phenomenon in the physics of strongly correlated electrons. Artificial single-impurity Kondo systems have been realized in various nanostructures, including sem...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/nature03422
更新日期：2005-03-24 00:00:00
