Abstract：
:In 1975-79, joint expeditions from Yale University and the Geological Survey of Pakistan (YGSP) recovered fossil lorisids in the Siwalik Group of Pakistan from four localities, spanning a period before 10 Myr ago to about 7 Myr ago. In three of the localities, only isolated teeth or fragments were found, whereas the fourth and youngest locality yielded dental, cranial and some postcranial remains of a single individual described here as a new genus and species. These specimens are the first fossil lorisids known from outside East Africa, and include the only recovered postcranial remains from slow-moving arboreal lorisines. The findings indicate that significant tracts of forests in the Siwalik environmental mosaic may have been utilized by ominoid primates, notably Ramapithecus.
journal_name
Naturejournal_title
Natureauthors
Jacobs LLdoi
10.1038/289585a0subject
Has Abstractpub_date
1981-02-12 00:00:00pages
585-7issue
5798eissn
0028-0836issn
1476-4687journal_volume
289pub_type
历史文章,杂志文章相关文献
NATURE文献大全abstract：:Plate tectonics successfully describes the surface of Earth as a mosaic of moving lithospheric plates. But it is not clear what happens at the base of the plates, the lithosphere-asthenosphere boundary (LAB). The LAB has been well imaged with converted teleseismic waves, whose 10-40-kilometre wavelength controls the s...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/nature14146
更新日期：2015-02-05 00:00:00
abstract：:Initial studies of somatically acquired mutations in immunoglobulin V regions from hybridomas and myelomas that are not derived from joining aberrations, suggested a controlled and specific hypermutation process, because spontaneous mutation rates observed for other genes are extremely low. Some evidence for the idea ...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/326405a0
更新日期：1987-03-26 00:00:00
abstract：:The advent of endothermy, which is achieved through the continuous homeostatic regulation of body temperature and metabolism1,2, is a defining feature of mammalian and avian evolution. However, when challenged by food deprivation or harsh environmental conditions, many mammalian species initiate adaptive energy-conser...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/s41586-020-2387-5
更新日期：2020-07-01 00:00:00
abstract：:Fermi-liquid theory (the standard model of metals) has been challenged by the discovery of anomalous properties in an increasingly large number of metals. The anomalies often occur near a quantum critical point--a continuous phase transition in the limit of absolute zero, typically between magnetically ordered and par...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/nature01968
更新日期：2003-10-09 00:00:00
abstract：:The rat hippocampus receives a strong cholinergic innervation from the medial septum; information about the development and function of this pathway could help to elucidate the mechanisms of memory functions. Previous electrophysiological studies have shown that septal stimulation in vivo facilitates commissural and p...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/313577a0
更新日期：1985-02-14 00:00:00
abstract：:It has been established that many eukaryotic mRNAs contain poly(adenylic acid) tracts at their 3'-termini. The polyadenylation of mRNA occurs post-transcriptionally in the nucleus as a rapid, initial addition of 100-200 adenylate residues to the pre-mRNA (ref. 1). Subsequently, a slower chain extension (6-8 bases) of ...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/267178a0
更新日期：1977-05-12 00:00:00
abstract：:The development of catalyst-controlled stereoselective olefin metathesis processes has been a pivotal recent advance in chemistry. The incorporation of appropriate ligands within complexes based on molybdenum, tungsten and ruthenium has led to reactivity and selectivity levels that were previously inaccessible. Here w...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/nature21043
更新日期：2017-02-02 00:00:00
abstract：:Ribosomes are translational machineries that catalyse protein synthesis. Ribosome structures from various species are known at the atomic level, but obtaining the structure of the human ribosome has remained a challenge; efforts to address this would be highly relevant with regard to human diseases. Here we report the...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/nature14427
更新日期：2015-04-30 00:00:00
abstract：:Cell-free DNA in the blood provides a non-invasive diagnostic avenue for patients with cancer1. However, characteristics of the origins and molecular features of cell-free DNA are poorly understood. Here we developed an approach to evaluate fragmentation patterns of cell-free DNA across the genome, and found that prof...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/s41586-019-1272-6
更新日期：2019-06-01 00:00:00
abstract：:Individuals with congenital or acquired prolongation of the QT interval, or long QT syndrome (LQTS), are at risk of life-threatening ventricular arrhythmia. LQTS is commonly genetic in origin but can also be caused or exacerbated by environmental factors. A missense mutation in the L-type calcium channel Ca(V)1.2 lead...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/nature09855
更新日期：2011-03-10 00:00:00
abstract：:Helium-neon lasers emitting at 632.8 nm can influence the phytochrome controlled growth and development of plants more than a quarter of a mile away. It may therefore be possible to control the growth of crops using lasers to activate the phytochrome system. ...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/228970a0
更新日期：1970-12-05 00:00:00
abstract：:The population vector hypothesis was introduced almost twenty years ago to illustrate that a population vector constructed from neural activity in primary motor cortex (MI) of non-human primates could predict the direction of hand movement during reaching. Alternative explanations for this population signal have been ...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/35093102
更新日期：2001-09-13 00:00:00
abstract：:Menopause is associated with bone loss and enhanced visceral adiposity. A polyclonal antibody that targets the β-subunit of the pituitary hormone follicle-stimulating hormone (Fsh) increases bone mass in mice. Here, we report that this antibody sharply reduces adipose tissue in wild-type mice, phenocopying genetic hap...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/nature22342
更新日期：2017-06-01 00:00:00
abstract：:Type II DNA topoisomerases are ubiquitous ATP-dependent enzymes capable of transporting a DNA through a transient double-strand break in a second DNA segment. This enables them to untangle DNA and relax the interwound supercoils (plectonemes) that arise in twisted DNA. In vivo, they are responsible for untangling repl...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/35009144
更新日期：2000-04-20 00:00:00
abstract：:'Pioneer' transcription factors are required for stem-cell pluripotency, cell differentiation and cell reprogramming1,2. Pioneer factors can bind nucleosomal DNA to enable gene expression from regions of the genome with closed chromatin. SOX2 is a prominent pioneer factor that is essential for pluripotency and self-re...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/s41586-020-2195-y
更新日期：2020-04-01 00:00:00
abstract：: ...
journal_title：Nature
pub_type： 新闻
doi：10.1038/d41586-019-00588-x
更新日期：2019-02-01 00:00:00
abstract：:The colorectal adenoma-carcinoma sequence has provided a paradigmatic framework for understanding the successive somatic genetic changes and consequent clonal expansions that lead to cancer1. However, our understanding of the earliest phases of colorectal neoplastic changes-which may occur in morphologically normal ti...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/s41586-019-1672-7
更新日期：2019-10-01 00:00:00
abstract：:Lake Victoria, together with its satellite lakes, harbours roughly 200 endemic forms of cichlid fishes that are classified as 'haplochromines' and yet the lake system is less than a million years old. This 'flock' has attracted attention because of the possibility that it evolved within the lake from one ancestral spe...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/347550a0
更新日期：1990-10-11 00:00:00
abstract：:The structure of foot-and-mouth disease virus has been determined at close to atomic resolution by X-ray diffraction without experimental phase information. The virus shows similarities with other picornaviruses but also several unique features. The canyon or pit found in other picornaviruses is absent; this has impor...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/337709a0
更新日期：1989-02-23 00:00:00
abstract：:Antiviral T cells are thought to regulate whether hepatitis C virus (HCV) and human immunodeficiency virus (HIV) infections result in viral control, asymptomatic persistence or severe disease, although the reasons for these different outcomes remain unclear. Recent genetic evidence, however, has indicated a correlatio...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/nature10624
更新日期：2011-11-20 00:00:00
abstract：:A putative growth hormone receptor from rabbit liver and the growth hormone binding protein from rabbit serum have the same amino-terminal amino-acid sequence, indicating that the binding protein corresponds to the extracellular hormone-binding domain of the liver receptor. The complete amino-acid sequences derived fr...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/330537a0
更新日期：1987-12-10 00:00:00
abstract：:Tumour suppressor genes (TSGs) inhibiting normal cellular growth are frequently silenced epigenetically in cancer. DNA methylation is commonly associated with TSG silencing, yet mutations in the DNA methylation initiation and recognition machinery in carcinogenesis are unknown. An intriguing possible mechanism for gen...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/nature06468
更新日期：2008-01-10 00:00:00
abstract：:Diatoms are one of the most ecologically successful classes of photosynthetic marine eukaryotes in the contemporary oceans. Over the past 30 million years, they have helped to moderate Earth's climate by absorbing carbon dioxide from the atmosphere, sequestering it via the biological carbon pump and ultimately burying...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/nature14599
更新日期：2015-08-20 00:00:00
abstract：:Cyclic ADP-ribose (cADPR) is a newly identified nucleotide which can release calcium from a variety of cells, suggesting it is a messenger for mobilizing internal Ca2+ stores. Its cyclic structure has now been confirmed by X-ray crystallography. Available results are consistent with it being a modulator of Ca(2+)-indu...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/370307a0
更新日期：1994-07-28 00:00:00
abstract：:The kidney has been widely exploited as a model system for the study of tissue inductions regulating vertebrate organogenesis. Kidney development is initiated by the ingrowth of the Wolfian duct-derived ureteric bud into the presumptive kidney mesenchyme. In response to a signal from the ureter, mesenchymal cells cond...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/372679a0
更新日期：1994-12-15 00:00:00
abstract：:If not properly processed and repaired, DNA double-strand breaks (DSBs) can give rise to deleterious chromosome rearrangements, which could ultimately lead to the tumour phenotype. DSB ends are resected in a 5' to 3' fashion in cells, to yield single-stranded DNA (ssDNA) for the recruitment of factors critical for DNA...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/nature09318
更新日期：2010-09-02 00:00:00
abstract：:Transparent electronic devices formed on flexible substrates are expected to meet emerging technological demands where silicon-based electronics cannot provide a solution. Examples of active flexible applications include paper displays and wearable computers. So far, mainly flexible devices based on hydrogenated amorp...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/nature03090
更新日期：2004-11-25 00:00:00
abstract：: ...
journal_title：Nature
pub_type： 评论,新闻
doi：10.1038/d41586-018-07224-0
更新日期：2018-11-01 00:00:00
abstract：:Retroviral integration is catalysed by a tetramer of integrase (IN) assembled on viral DNA ends in a stable complex, known as the intasome. How the intasome interfaces with chromosomal DNA, which exists in the form of nucleosomal arrays, is currently unknown. Here we show that the prototype foamy virus (PFV) intasome ...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/nature14495
更新日期：2015-07-16 00:00:00
abstract：:Non-volcanic tremor is a weak, extended duration seismic signal observed episodically on some major faults, often in conjunction with slow slip events. Such tremor may hold the key to understanding fundamental processes at the deep roots of faults, and could signal times of accelerated slip and hence increased seismic...
journal_title：Nature
pub_type： 杂志文章
doi：10.1038/nature05666
更新日期：2007-03-15 00:00:00
