Fermi-liquid breakdown in the paramagnetic phase of a pure metal.

abstract：:The spontaneously hypertensive rat and the stroke-prone spontaneously hypertensive rat are useful models for human hypertension. In these strains hypertension is a polygenic trait, in which both autosomal and sex-linked genes can influence blood pressure. Linkage studies in crosses between the stroke-prone spontaneous...

journal_title：Nature

authors： Hilbert P,Lindpaintner K,Beckmann JS,Serikawa T,Soubrier F,Dubay C,Cartwright P,De Gouyon B,Julier C,Takahasi S

更新日期：1991-10-10 00:00:00

abstract：:It has long been contentious whether the large representation of the fovea in the primate visual cortex (V1) indicates a selective magnification of this part of the retina, or whether it merely reflects the density of retinal ganglion cells. The measurement of the retinal ganglion-cell density is complicated by latera...

journal_title：Nature

authors： Wässle H,Grünert U,Röhrenbeck J,Boycott BB

更新日期：1989-10-19 00:00:00

abstract：:Although there are substantial differences between the magnetospheres of Jupiter and Saturn, it has been suggested that cryovolcanic activity at Enceladus could lead to electrodynamic coupling between Enceladus and Saturn like that which links Jupiter with Io, Europa and Ganymede. Powerful field-aligned electron beams...

journal_title：Nature

authors： Pryor WR,Rymer AM,Mitchell DG,Hill TW,Young DT,Saur J,Jones GH,Jacobsen S,Cowley SW,Mauk BH,Coates AJ,Gustin J,Grodent D,Gérard JC,Lamy L,Nichols JD,Krimigis SM,Esposito LW,Dougherty MK,Jouchoux AJ,Stewart AI,Mc

更新日期：2011-04-21 00:00:00

abstract：:Representations of sensory stimuli in the cerebral cortex can undergo progressive remodelling according to the behavioural importance of the stimuli. The cortex receives widespread projections from dopamine neurons in the ventral tegmental area (VTA), which are activated by new stimuli or unpredicted rewards, and are ...

journal_title：Nature

authors： Bao S,Chan VT,Merzenich MM

更新日期：2001-07-05 00:00:00

abstract：:The cellular response to hypoxia is critical for cell survival and is fine-tuned to allow cells to recover from hypoxic stress and adapt to heterogeneous or fluctuating oxygen levels. The hypoxic response is mediated by the α-subunit of the transcription factor HIF-1 (HIF-1α), which interacts through its intrinsically...

journal_title：Nature

authors： Berlow RB,Dyson HJ,Wright PE

更新日期：2017-03-16 00:00:00

abstract：:The widespread reorganization of cellular architecture in mitosis is achieved through extensive protein phosphorylation, driven by the coordinated activation of a mitotic kinase network and repression of counteracting phosphatases. Phosphatase activity must subsequently be restored to promote mitotic exit. Although Cd...

journal_title：Nature

authors： Grallert A,Boke E,Hagting A,Hodgson B,Connolly Y,Griffiths JR,Smith DL,Pines J,Hagan IM

更新日期：2015-01-01 00:00:00

abstract：:The genetic relationships of human populations have been studied by comparing gene frequency data for protein and blood-group loci of different populations. DNA analysis now promises to be more informative since not only do the DNA coding sequences have more variation than their corresponding proteins but, in addition...

journal_title：Nature

authors： Wainscoat JS,Hill AV,Boyce AL,Flint J,Hernandez M,Thein SL,Old JM,Lynch JR,Falusi AG,Weatherall DJ

更新日期：1986-02-06 00:00:00

abstract：: ...

journal_title：Nature

authors： Freeman M

更新日期：2018-10-01 00:00:00

abstract：:Mitochondria take up and extrude various inorganic and organic ions, as well as larger substances such as proteins. The technique of patch clamping should provide real-time information on such transport and on energy transduction in oxidative phosphorylation. It has been applied to detect microscopic currents from mit...

journal_title：Nature

authors： Inoue I,Nagase H,Kishi K,Higuti T

更新日期：1991-07-18 00:00:00

abstract：:Neuroectoderm cells in the cortical ventricular zone generate many diverse cell types, maintain the ventricular zone during embryonic life and create another germinal layer, the subventricular zone, which persists into adulthood. In other vertebrate tissues, including skin, intestine, blood and neural crest, stem cell...

journal_title：Nature

authors： Davis AA,Temple S

更新日期：1994-11-17 00:00:00

abstract：:About one-third of the carbon dioxide (CO(2)) released into the atmosphere as a result of human activity has been absorbed by the oceans, where it partitions into the constituent ions of carbonic acid. This leads to ocean acidification, one of the major threats to marine ecosystems and particularly to calcifying organ...

journal_title：Nature

authors： Beaufort L,Probert I,de Garidel-Thoron T,Bendif EM,Ruiz-Pino D,Metzl N,Goyet C,Buchet N,Coupel P,Grelaud M,Rost B,Rickaby RE,de Vargas C

更新日期：2011-08-03 00:00:00

abstract：:The hydrosulphide ion (HS(-)) and its undissociated form, hydrogen sulphide (H(2)S), which are believed to have been critical to the origin of life on Earth, remain important in physiology and cellular signalling. As a major metabolite in anaerobic bacterial growth, hydrogen sulphide is a product of both assimilatory ...

journal_title：Nature

authors： Czyzewski BK,Wang DN

更新日期：2012-03-11 00:00:00

abstract：:Studies of galaxy surveys in the context of the cold dark matter paradigm have shown that the mass of the dark matter halo and the total stellar mass are coupled through a function that varies smoothly with mass. Their average ratio Mhalo/Mstars has a minimum of about 30 for galaxies with stellar masses near that of t...

journal_title：Nature

authors： van Dokkum P,Danieli S,Cohen Y,Merritt A,Romanowsky AJ,Abraham R,Brodie J,Conroy C,Lokhorst D,Mowla L,O'Sullivan E,Zhang J

更新日期：2018-03-28 00:00:00

abstract：:Although many animals use the Earth's magnetic field for orientation and navigation, the precise biophysical mechanisms underlying magnetic sensing have been elusive. One theoretical model proposes that geomagnetic fields are perceived by chemical reactions involving specialized photoreceptors. However, the specific p...

journal_title：Nature

authors： Gegear RJ,Casselman A,Waddell S,Reppert SM

更新日期：2008-08-21 00:00:00

abstract：:Injury causes a systemic inflammatory response syndrome (SIRS) that is clinically much like sepsis. Microbial pathogen-associated molecular patterns (PAMPs) activate innate immunocytes through pattern recognition receptors. Similarly, cellular injury can release endogenous 'damage'-associated molecular patterns (DAMPs...

journal_title：Nature

authors： Zhang Q,Raoof M,Chen Y,Sumi Y,Sursal T,Junger W,Brohi K,Itagaki K,Hauser CJ

更新日期：2010-03-04 00:00:00

abstract：:The formation of disulphide bonds is essential to the structure and function of proteins. These bonds rapidly form either cotranslationally or immediately post-translationally in the lumen of the endoplasmic reticulum. Native disulphide pairing for such proteins has been achieved in vitro; however, the rates of reasse...

journal_title：Nature

authors： Edman JC,Ellis L,Blacher RW,Roth RA,Rutter WJ

更新日期：1985-09-19 00:00:00

abstract：:The nicotinic acetylcholine receptor (AChR) from the electroplax of the ray Torpedo californica is composed of five subunits present in a molar stoichiometry of alpha 2 beta gamma delta (refs 1-3) and contains both the binding site for the neurotransmitter and the cation gating unit (reviewed in refs 4-6). We have rec...

journal_title：Nature

authors： Noda M,Takahashi H,Tanabe T,Toyosato M,Kikyotani S,Furutani Y,Hirose T,Takashima H,Inayama S,Miyata T,Numa S

更新日期：1983-04-07 00:00:00

abstract：:Manic depression is a severe cyclic mental illness that can be unipolar or bipolar and has a lifetime risk of approximately 7 per 1,000 in most populations. Families with multiple cases of manic depression have been described that are compatible with both autosomal dominant and X-linked modes of genetic transmission. ...

journal_title：Nature

authors： Hodgkinson S,Sherrington R,Gurling H,Marchbanks R,Reeders S,Mallet J,McInnis M,Petursson H,Brynjolfsson J

更新日期：1987-02-26 00:00:00

abstract：:In Dictyostelium discoideum, carbohydrate binding proteins (CBPs) or lectins have been implicated in the molecular basis of cellular cohesion. To determine the role of these CBPs, we have attempted to isolate structural gene mutants in which the CBPs have a defective affinity for carbohydrate ligands. We now report th...

journal_title：Nature

authors： Ray J,Shinnick T,Lerner R

更新日期：1979-05-17 00:00:00

abstract：:Ia antigens are membrane-bound glycoproteins that play a part in antigen recognition and subsequent cell-cell interactions in the immune response. In the mouse they are coded for by the I region of the major histocompatibility complex H-2 and have been demonstrated on B lymphocytes, monocytes, activated T cells, macro...

journal_title：Nature

authors： de Waal RM,Bogman MJ,Maass CN,Cornelissen LM,Tax WJ,Koene RA

更新日期：1983-06-02 00:00:00

abstract：:The Philadelphia chromosome, a chromosomal abnormality that encodes BCR-ABL1, is the defining lesion of chronic myelogenous leukaemia (CML) and a subset of acute lymphoblastic leukaemia (ALL). To define oncogenic lesions that cooperate with BCR-ABL1 to induce ALL, we performed a genome-wide analysis of diagnostic leuk...

journal_title：Nature

authors： Mullighan CG,Miller CB,Radtke I,Phillips LA,Dalton J,Ma J,White D,Hughes TP,Le Beau MM,Pui CH,Relling MV,Shurtleff SA,Downing JR

更新日期：2008-05-01 00:00:00

abstract：:The AP-1 family of transcription factors, which includes the proto-oncogene products c-Jun and c-Fos, controls the stimulation of cellular genes by growth factors and the expression of oncogenes, including src and ras. Transcriptional activation by c-Jun is regulated by a cell-type-specific inhibitor that represses th...

journal_title：Nature

authors： Baichwal VR,Park A,Tjian R

更新日期：1991-07-11 00:00:00

abstract：:Apoptosis in the immune system is a fundamental process regulating lymphocyte maturation, receptor repertoire selection and homeostasis. Thus, death by apoptosis is as essential for the function of lymphocytes as growth and differentiation. This article focuses on death receptor-associated apoptosis and the role of CD...

journal_title：Nature

authors： Krammer PH

更新日期：2000-10-12 00:00:00

abstract：:The proton-activated chloride channel (PAC) is active across a wide range of mammalian cells and is involved in acid-induced cell death and tissue injury1-3. PAC has recently been shown to represent a novel and evolutionarily conserved protein family4,5. Here we present two cryo-electron microscopy structures of human...

journal_title：Nature

authors： Ruan Z,Osei-Owusu J,Du J,Qiu Z,Lü W

更新日期：2020-12-01 00:00:00

abstract：:CD4(+) T helper 2 (T(H)2) cells secrete interleukin (IL)4, IL5 and IL13, and are required for immunity to gastrointestinal helminth infections. However, T(H)2 cells also promote chronic inflammation associated with asthma and allergic disorders. The non-haematopoietic-cell-derived cytokines thymic stromal lymphopoieti...

journal_title：Nature

authors： Saenz SA,Siracusa MC,Perrigoue JG,Spencer SP,Urban JF Jr,Tocker JE,Budelsky AL,Kleinschek MA,Kastelein RA,Kambayashi T,Bhandoola A,Artis D

更新日期：2010-04-29 00:00:00

abstract：:Ionic currents from individual K+ channels in squid axon membrane have been recorded. At hyperpolarizing membrane voltages, unit events occur as widely spaced rectangular pulses with short interruptions. The frequency of occurrence of the units increases strongly when the membrane is depolarized. ...

journal_title：Nature

authors： Conti F,Neher E

更新日期：1980-05-15 00:00:00

abstract：:Several distinct cell lineages are established during mouse embryogenesis. The trophectoderm and primitive endoderm give rise to extraembryonic structures alone, while the primitive ectoderm becomes the fetus proper. Recent studies suggest that the levels of DNA modification are lower in inactive X chromosomes from ex...

journal_title：Nature

authors： Chapman V,Forrester L,Sanford J,Hastie N,Rossant J

更新日期：1984-01-19 00:00:00

abstract：:The evolution of the middle ear is central to the discussion of how the first tetrapods adapted to life on land as well as their phylogeny. Here I report the discovery of the stapes of Acanthostega gunnari, from the Upper Devonian of east Greenland. This is the earliest tetrapod stapes so far described, and it throws ...

journal_title：Nature

authors： Clack JA

更新日期：1989-11-23 00:00:00

abstract：:It is well established that the osteoclast is formed by fusion of post-mitotic, mononuclear precursors derived from circulating progenitor cells. However, the precise haematopoietic origin of the osteoclast is unknown. We have investigated this here by fractionating mouse bone marrow and isolating haematopoietic stem ...

journal_title：Nature

authors： Scheven BA,Visser JW,Nijweide PJ

更新日期：1986-05-01 00:00:00

abstract：:The three-dimensional structure of intact human rhinovirus 14 (HRV-14) complexed with Fab fragments (Fab17-IA) from a strongly neutralizing antibody that binds bivalently to the virion has been determined to 4.0 angstrom resolution by a combination of X-ray crystallography and cryo-electron microscopy. In contradictio...

journal_title：Nature

authors： Smith TJ,Chase ES,Schmidt TJ,Olson NH,Baker TS

更新日期：1996-09-26 00:00:00