Abstract:
:Cross-modal processing enables the utilization of information received via different sensory organs to facilitate more complicated human actions. We used functional MRI on early-blind individuals to study the neural processes associated with cross auditory-spatial learning. The auditory signals, converted from echoes of ultrasonic signals emitted from a navigation device, were novel to the participants. The subjects were trained repeatedly for 4 weeks in associating the auditory signals with different distances. Subjects' blood-oxygenation-level-dependent responses were captured at baseline and after training using a sound-to-distance judgment task. Whole-brain analyses indicated that the task used in the study involved auditory discrimination as well as spatial localization. The learning process was shown to be mediated by the inferior parietal cortex and the hippocampus, suggesting the integration and binding of auditory features to distances. The right cuneus was found to possibly serve a general rather than a specific role, forming an occipital-enhanced network for cross auditory-spatial learning. This functional network is likely to be unique to those with early blindness, since the normal-vision counterparts shared activities only in the parietal cortex.
journal_name
Hum Brain Mappjournal_title
Human brain mappingauthors
Chan CC,Wong AW,Ting KH,Whitfield-Gabrieli S,He J,Lee TMdoi
10.1002/hbm.21395subject
Has Abstractpub_date
2012-11-01 00:00:00pages
2714-27issue
11eissn
1065-9471issn
1097-0193journal_volume
33pub_type
杂志文章abstract::Mental calculation is a complex mental procedure involving a frontoparietal network of brain regions. Functional MRI (fMRI) studies have revealed interesting characteristics of these regions, but the precise function of some areas remains elusive. In the present study, we used electrocorticographic (ECoG) recordings t...
journal_title:Human brain mapping
pub_type: 杂志文章
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abstract::Differences in brain activity of children with attention deficit hyperactivity disorder (ADHD) have been compared to normal healthy controls, suggesting neural correlates of cognitive/behavioral symptoms. Symptoms are improved with methylphenidate treatment but limited sources can be cited to show how brain activity i...
journal_title:Human brain mapping
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21255
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20605
更新日期:2009-04-01 00:00:00
abstract::Inattentional deafness is the failure to hear otherwise audible sounds (usually alarms) that may occur under high workload conditions. One potential cause for its occurrence could be an attentional bottleneck that occurs when task demands are high, resulting in lack of resources for processing of additional tasks. In ...
journal_title:Human brain mapping
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abstract::Voxel-based analyses (VBA) are increasingly being used to detect white matter abnormalities with diffusion tensor imaging (DTI) in different types of pathologies. However, the validity, specificity, and sensitivity of statistical inferences of group differences to a large extent depend on the quality of the spatial no...
journal_title:Human brain mapping
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journal_title:Human brain mapping
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journal_title:Human brain mapping
pub_type: 杂志文章
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journal_title:Human brain mapping
pub_type: 杂志文章
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abstract:BACKGROUND:Reduced cortical thickness is a candidate biological marker of depression, although findings are inconsistent. This could reflect analytic heterogeneity, such as use of region-wise cortical thickness based on the Freesurfer Desikan-Killiany (DK) atlas or surface-based morphometry (SBM). The Freesurfer Destri...
journal_title:Human brain mapping
pub_type: 杂志文章,多中心研究,随机对照试验
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journal_title:Human brain mapping
pub_type: 杂志文章
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更新日期:2003-03-01 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20468
更新日期:2008-12-01 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章
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更新日期:2020-07-13 00:00:00
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journal_title:Human brain mapping
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更新日期:2018-08-01 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23214
更新日期:2016-08-01 00:00:00
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journal_title:Human brain mapping
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20388
更新日期:2008-03-01 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章
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journal_title:Human brain mapping
pub_type: 杂志文章
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pub_type: 杂志文章,meta分析
doi:10.1002/hbm.23132
更新日期:2016-05-01 00:00:00
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更新日期:2015-03-01 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20868
更新日期:2010-03-01 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章
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更新日期:2014-05-01 00:00:00
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