Abstract:
:There are an increasing number of neuroimaging studies that allow a better understanding of symptoms, neural correlates and associated conditions of fibromyalgia. However, the results of these studies are difficult to compare, as they include a heterogeneous group of patients, use different stimulation paradigms, tasks, and the statistical evaluation of neuroimaging data shows high variability. Therefore, this meta-analytic approach aimed at evaluating potential alterations in neuronal brain activity or structure related to pain processing in fibromyalgia syndrome (FMS) patients, using quantitative coordinate-based "activation likelihood estimation" (ALE) meta-analysis. 37 FMS papers met the inclusion criteria for an ALE analysis (1,264 subjects, 274 activation foci). A pooled ALE analysis of different modalities of neuroimaging and additional analyses according functional and structural changes indicated differences between FMS patients and controls in the insula, amygdala, anterior/mid cingulate cortex, superior temporal gyrus, the primary and secondary somatosensory cortex, and lingual gyrus. Our analysis showed consistent results across FMS studies with potential abnormalities especially in pain-related brain areas. Given that similar alterations have already been demonstrated in patients with other chronic pain conditions and the lack of adequate control groups of chronic pain subjects in most FMS studies, it is not clear however, whether these findings are associated with chronic pain in general or are unique features of patients with FMS. Hum Brain Mapp 37:1749-1758, 2016. © 2016 Wiley Periodicals, Inc.
journal_name
Hum Brain Mappjournal_title
Human brain mappingauthors
Dehghan M,Schmidt-Wilcke T,Pfleiderer B,Eickhoff SB,Petzke F,Harris RE,Montoya P,Burgmer Mdoi
10.1002/hbm.23132subject
Has Abstractpub_date
2016-05-01 00:00:00pages
1749-58issue
5eissn
1065-9471issn
1097-0193journal_volume
37pub_type
杂志文章,meta分析abstract::The goal of this study was to document current clinical practice and report patient outcomes in presurgical language functional MRI (fMRI) for epilepsy surgery. Epilepsy surgical programs worldwide were surveyed as to the utility, implementation, and efficacy of language fMRI in the clinic; 82 programs responded. Resp...
journal_title:Human brain mapping
pub_type: 杂志文章
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abstract::The motivation to receive rewards enhances episodic memories, and the motivation is modulated by task difficulty. In episodic retrieval, however, functional neuroimaging evidence regarding the motivation that mediates interactions between reward and task difficulty is scarce. The present fMRI study investigated this i...
journal_title:Human brain mapping
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journal_title:Human brain mapping
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.25245
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journal_title:Human brain mapping
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journal_title:Human brain mapping
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pub_type: 杂志文章,随机对照试验
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journal_title:Human brain mapping
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journal_title:Human brain mapping
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20298
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21048
更新日期:2011-04-01 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20519
更新日期:2009-02-01 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20941
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journal_title:Human brain mapping
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doi:10.1002/hbm.24208
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doi:10.1002/hbm.22162
更新日期:2014-01-01 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23976
更新日期:2018-05-01 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23446
更新日期:2017-03-01 00:00:00
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journal_title:Human brain mapping
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doi:10.1002/hbm.22401
更新日期:2014-07-01 00:00:00
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journal_title:Human brain mapping
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journal_title:Human brain mapping
pub_type: 杂志文章,评审
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更新日期:2020-06-05 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章
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更新日期:2020-02-15 00:00:00
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journal_title:Human brain mapping
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doi:10.1002/hbm.22079
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22547
更新日期:2014-10-01 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20420
更新日期:2008-05-01 00:00:00
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journal_title:Human brain mapping
pub_type: 杂志文章
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更新日期:2014-08-01 00:00:00
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