Altered functional connectivity of primary visual cortex in early blindness.

Abstract:

:In early blindness, the primary visual area (PVA) loses the ability to process visual information, and shifts to working on the processing of somatosensory input, auditory input, and some higher-level cognitive functions. It has not yet been investigated whether such functional changes can lead to alterations of the functional connectivity between the PVA and other brain areas in resting state. The purpose of this study is to investigate the differences in the functional connectivity of the PVA between early blind and sighted subjects using resting functional MRI data. The altered functional connectivity was identified by comparing the correlation coefficients of the PVA with other brain areas between 16 early blind subjects (blindness onset within 1 year of age) and 32 gender- and age-matched healthy sighted volunteers. Compared with the sighted, the early blind subjects showed decreased functional connectivity between the left PVA and the bilateral supplementary motor area (SMA), pre- and postcentral gyri, superior parietal lobule, and the left superior and middle temporal gyri. Early blind subjects also showed decreased functional connectivity between the right PVA and the bilateral SMA, pre- and postcentral gyri. Our findings suggest that early deprivation of a single sensory modality induces alterations of functional connectivity between the deprived functional area and other associated brain areas.

journal_name

Hum Brain Mapp

journal_title

Human brain mapping

authors

Yu C,Liu Y,Li J,Zhou Y,Wang K,Tian L,Qin W,Jiang T,Li K

doi

10.1002/hbm.20420

subject

Has Abstract

pub_date

2008-05-01 00:00:00

pages

533-43

issue

5

eissn

1065-9471

issn

1097-0193

journal_volume

29

pub_type

杂志文章
  • Altered frontal-parietal functioning during verbal working memory in children and adolescents with heavy prenatal alcohol exposure.

    abstract::This study evaluated the neural basis of verbal working memory (WM) function in a group of 20 children and adolescents with fetal alcohol spectrum disorders (FASDs) and 20 typically developing comparison participants using functional magnetic resonance imaging (fMRI). Both groups showed prominent activation in the fro...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.20741

    authors: O'Hare ED,Lu LH,Houston SM,Bookheimer SY,Mattson SN,O'Connor MJ,Sowell ER

    更新日期:2009-10-01 00:00:00

  • Spontaneous blood oxygenation level-dependent fMRI signal is modulated by behavioral state and correlates with evoked response in sensorimotor cortex: a 7.0-T fMRI study.

    abstract::Synchrony measurements of spontaneous low-frequency blood oxygenation level-dependent (BOLD) fluctuations are increasingly being used to investigate spatial regions of functional connectivity. Although information regarding BOLD-BOLD synchrony between different regions is frequently reported, the relationship between ...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.21228

    authors: Donahue MJ,Hoogduin H,Smith SM,Siero JC,Chappell M,Petridou N,Jezzard P,Luijten PR,Hendrikse J

    更新日期:2012-03-01 00:00:00

  • Dorsolateral prefrontal circuit effective connectivity mediates the relationship between white matter structure and PASAT-3 performance in multiple sclerosis.

    abstract::Three decades ago a series of parallel circuits were described involving the frontal cortex and deep grey matter structures, with putative roles in control of motor and oculomotor function, cognition, behaviour and emotion. The circuit comprising the dorsolateral prefrontal cortex, caudate, globus pallidus and thalamu...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.25239

    authors: Meng D,Welton T,Elsarraj A,Morgan PS,das Nair R,Constantinescu CS,Evangelou N,Auer DP,Dineen RA

    更新日期:2020-10-19 00:00:00

  • Modular-level alterations of structure-function coupling in schizophrenia connectome.

    abstract::Convergent evidences have revealed that schizophrenia is associated with brain dysconnectivity, which leads to abnormal network organization. However, discrepancies were apparent between the structural connectivity (SC) and functional connectivity (FC) studies, and the relationship between structural and functional de...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.23501

    authors: Sun Y,Dai Z,Li J,Collinson SL,Sim K

    更新日期:2017-04-01 00:00:00

  • Spatial elongation of population receptive field profiles revealed by model-free fMRI back-projection.

    abstract::Estimates of visual field topographies in human visual cortex obtained through fMRI traveling wave techniques usually provide the parameters of population receptive field (pRF) location (polar angle, eccentricity) and receptive field size. These parameters are obtained by fitting the recorded data to a standard model ...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.24015

    authors: Merkel C,Hopf JM,Schoenfeld MA

    更新日期:2018-06-01 00:00:00

  • Neural correlates of word production stages delineated by parametric modulation of psycholinguistic variables.

    abstract::Word production is a complex multistage process linking conceptual representations, lexical entries, phonological forms and articulation. Previous studies have revealed a network of predominantly left-lateralized brain regions supporting this process, but many details regarding the precise functions of different nodes...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.20782

    authors: Wilson SM,Isenberg AL,Hickok G

    更新日期:2009-11-01 00:00:00

  • Subcortical structural variations associated with low socioeconomic status in adolescents.

    abstract::Low socioeconomic status (SES) is associated with a higher probability of multiple exposures (e.g., neighborhood violence, poor nutrition, housing instability, air pollution, and insensitive caregiving) known to affect structural development of subcortical brain regions that subserve threat and reward processing, howe...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.24796

    authors: Jenkins LM,Chiang JJ,Vause K,Hoffer L,Alpert K,Parrish TB,Wang L,Miller GE

    更新日期:2020-01-01 00:00:00

  • Encoding touch and the orbitofrontal cortex.

    abstract::Lesion studies on nonhuman primates utilizing recognition memory tests have shown that the orbitofrontal cortex is critical for the encoding of novel information, and anatomical studies have shown that the orbitofrontal cortex forms part of a mnemonic circuit that connects limbic medial temporal areas with higher-orde...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.20532

    authors: Frey S,Zlatkina V,Petrides M

    更新日期:2009-02-01 00:00:00

  • Structural brain correlates of cognitive and behavioral impairment in MND.

    abstract:OBJECTIVE:To assess the structural correlates of cognitive and behavioral impairment in motor neuron diseases (MND) using multimodal MRI. METHODS:One hundred one patients with sporadic MND (56 classic amyotrophic lateral sclerosis, 31 upper motor neuron phenotype, and 14 lower motor neuron phenotype) and 51 controls w...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.23124

    authors: Agosta F,Ferraro PM,Riva N,Spinelli EG,Chiò A,Canu E,Valsasina P,Lunetta C,Iannaccone S,Copetti M,Prudente E,Comi G,Falini A,Filippi M

    更新日期:2016-04-01 00:00:00

  • Abnormal neural response to phonological working memory demands in persistent developmental stuttering.

    abstract::Persistent developmental stuttering is a neurological disorder that commonly manifests as a motor problem. Cognitive theories, however, hold that poorly developed cognitive skills are the origins of stuttering. Working memory (WM), a multicomponent cognitive system that mediates information maintenance and manipulatio...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.24366

    authors: Yang Y,Jia F,Fox PT,Siok WT,Tan LH

    更新日期:2019-01-01 00:00:00

  • Neural correlates of successful semantic processing during propofol sedation.

    abstract::Sedation has a graded effect on brain responses to auditory stimuli: perceptual processing persists at sedation levels that attenuate more complex processing. We used fMRI in healthy volunteers sedated with propofol to assess changes in neural responses to spoken stimuli. Volunteers were scanned awake, sedated, and du...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.22375

    authors: Adapa RM,Davis MH,Stamatakis EA,Absalom AR,Menon DK

    更新日期:2014-07-01 00:00:00

  • Monocular visual activation patterns in albinism as revealed by functional magnetic resonance imaging.

    abstract::Human albinism is characterized by a disturbance of the chiasmatic projection system leading to predominant representation of just one eye in the contralateral hemisphere. Patients show congenital nystagmus without perceiving oscillopsia. The purpose of the present study was to demonstrate the consequences of atypical...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.20046

    authors: Schmitz B,Käsmann-Kellner B,Schäfer T,Krick CM,Grön G,Backens M,Reith W

    更新日期:2004-09-01 00:00:00

  • Use of anatomical parcellation to catalog and study structure-function relationships in the human brain.

    abstract::We describe a functional neuroanatomy approach that combines structural (MRI) and functional (PET) data at the individual level. For each subject MRI dataset, sulci are first localized using hemisphere surface rendering and sections and stored. Using these landmarks, the subject brain volume is then divided in 100 ana...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/(SICI)1097-0193(1997)5:4<228::AID-HBM4>3.0

    authors: Tzourio N,Petit L,Mellet E,Orssaud C,Crivello F,Benali K,Salamon G,Mazoyer B

    更新日期:1997-01-01 00:00:00

  • Different structural correlates for verbal memory impairment in temporal lobe epilepsy with and without mesial temporal lobe sclerosis.

    abstract:OBJECTIVES:Memory impairment is one of the most prominent cognitive deficits in temporal lobe epilepsy (TLE). The overall goal of this study was to explore the contribution of cortical and hippocampal (subfield) damage to impairment of auditory immediate recall (AIMrecall), auditory delayed recall (ADMrecall), and audi...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.21226

    authors: Mueller SG,Laxer KD,Scanlon C,Garcia P,McMullen WJ,Loring DW,Meador KJ,Weiner MW

    更新日期:2012-02-01 00:00:00

  • Three-dimensional linear and nonlinear transformations: an integration of light microscopical and MRI data.

    abstract::The registration of image volumes derived from different imaging modalities such as MRI, PET, SPECT, and CT has been described in numerous studies in which functional and morphological data are combined on the basis of macrostructural information. However, the exact topography of architectural details is defined by mi...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:

    authors: Schormann T,Zilles K

    更新日期:1998-01-01 00:00:00

  • Dynamic regional phase synchrony (DRePS): An Instantaneous Measure of Local fMRI Connectivity Within Spatially Clustered Brain Areas.

    abstract::Dynamic functional brain connectivity analysis is a fast expanding field in computational neuroscience research with the promise of elucidating brain network interactions. Sliding temporal window based approaches are commonly used in order to explore dynamic behavior of brain networks in task-free functional magnetic ...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.23151

    authors: Omidvarnia A,Pedersen M,Walz JM,Vaughan DN,Abbott DF,Jackson GD

    更新日期:2016-05-01 00:00:00

  • Modulation of 7 T fMRI Signal in the Cerebellar Cortex and Nuclei During Acquisition, Extinction, and Reacquisition of Conditioned Eyeblink Responses.

    abstract::Classical delay eyeblink conditioning is likely the most commonly used paradigm to study cerebellar learning. As yet, few studies have focused on extinction and savings of conditioned eyeblink responses (CRs). Saving effects, which are reflected in a reacquisition after extinction that is faster than the initial acqui...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.23641

    authors: Ernst TM,Thürling M,Müller S,Kahl F,Maderwald S,Schlamann M,Boele HJ,Koekkoek SKE,Diedrichsen J,De Zeeuw CI,Ladd ME,Timmann D

    更新日期:2017-08-01 00:00:00

  • Hemispheric specialization during mental imagery of brisk walking.

    abstract:OBJECTIVES:Brisk walking, a sensitive test to evaluate gait capacity in normal and pathological aging such as parkinsonism, is used as an alternative to classical fitness program for motor rehabilitation and may help to decrease the risk of cognitive deterioration observed with aging. In this study, we aimed to identif...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.21255

    authors: Crémers J,Dessoullières A,Garraux G

    更新日期:2012-04-01 00:00:00

  • Free-water and BOLD imaging changes in Parkinson's disease patients chronically treated with a MAO-B inhibitor.

    abstract::Rasagiline is a monoamine oxidase type B inhibitor that possesses no amphetamine-like properties, and provides symptomatic relief in early and late stages of Parkinson's disease (PD). Data in animal models of PD suggest that chronic administration of rasagiline is associated with structural changes in the substantia n...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.23213

    authors: Burciu RG,Ofori E,Shukla P,Pasternak O,Chung JW,McFarland NR,Okun MS,Vaillancourt DE

    更新日期:2016-08-01 00:00:00

  • Generalizability of machine learning for classification of schizophrenia based on resting-state functional MRI data.

    abstract::Machine learning has increasingly been applied to classification of schizophrenia in neuroimaging research. However, direct replication studies and studies seeking to investigate generalizability are scarce. To address these issues, we assessed within-site and between-site generalizability of a machine learning classi...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.24797

    authors: Cai XL,Xie DJ,Madsen KH,Wang YM,Bögemann SA,Cheung EFC,Møller A,Chan RCK

    更新日期:2020-01-01 00:00:00

  • Perceived communicative intent in gesture and language modulates the superior temporal sulcus.

    abstract::Behavioral evidence and theory suggest gesture and language processing may be part of a shared cognitive system for communication. While much research demonstrates both gesture and language recruit regions along perisylvian cortex, relatively less work has tested functional segregation within these regions on an indiv...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.23251

    authors: Redcay E,Velnoskey KR,Rowe ML

    更新日期:2016-10-01 00:00:00

  • Internal representations for face detection: an application of noise-based image classification to BOLD responses.

    abstract::What basic visual structures underlie human face detection and how can we extract such structures directly from the amplitude of neural responses elicited by face processing? Here, we address these issues by investigating an extension of noise-based image classification to BOLD responses recorded in high-level visual ...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.22128

    authors: Nestor A,Vettel JM,Tarr MJ

    更新日期:2013-11-01 00:00:00

  • Childhood maltreatment is associated with an automatic negative emotion processing bias in the amygdala.

    abstract:UNLABELLED:Major depression has been repeatedly associated with amygdala hyper-responsiveness to negative (but not positive) facial expressions at early, automatic stages of emotion processing using subliminally presented stimuli. However, it is not clear whether this "limbic bias" is a correlate of depression or repre...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.22112

    authors: Dannlowski U,Kugel H,Huber F,Stuhrmann A,Redlich R,Grotegerd D,Dohm K,Sehlmeyer C,Konrad C,Baune BT,Arolt V,Heindel W,Zwitserlood P,Suslow T

    更新日期:2013-11-01 00:00:00

  • Cortical brain responses during passive nonpainful median nerve stimulation at low frequencies (0.5-4 Hz): an fMRI study.

    abstract::Previous findings have shown that the human somatosensory cortical systems that are activated by passive nonpainful electrical stimulation include the contralateral primary somatosensory area (SI), bilateral secondary somatosensory area (SII), and bilateral insula. The present study tested the hypothesis that these ar...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.20292

    authors: Ferretti A,Babiloni C,Arienzo D,Del Gratta C,Rossini PM,Tartaro A,Romani GL

    更新日期:2007-07-01 00:00:00

  • A method for multitask fMRI data fusion applied to schizophrenia.

    abstract::It is becoming common to collect data from multiple functional magnetic resonance imaging (fMRI) paradigms on a single individual. The data from these experiments are typically analyzed separately and sometimes directly subtracted from one another on a voxel-by-voxel basis. These comparative approaches, although usefu...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.20204

    authors: Calhoun VD,Adali T,Kiehl KA,Astur R,Pekar JJ,Pearlson GD

    更新日期:2006-07-01 00:00:00

  • Heritability of regional and global brain structure at the onset of puberty: a magnetic resonance imaging study in 9-year-old twin pairs.

    abstract::Puberty represents the phase of sexual maturity, signaling the change from childhood into adulthood. During childhood and adolescence, prominent changes take place in the brain. Recently, variation in frontal, temporal, and parietal areas was found to be under varying genetic control between 5 and 19 years of age. How...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.20660

    authors: Peper JS,Schnack HG,Brouwer RM,Van Baal GC,Pjetri E,Székely E,van Leeuwen M,van den Berg SM,Collins DL,Evans AC,Boomsma DI,Kahn RS,Hulshoff Pol HE

    更新日期:2009-07-01 00:00:00

  • Predictive modeling of EEG time series for evaluating surgery targets in epilepsy patients.

    abstract::During the last 20 years, predictive modeling in epilepsy research has largely been concerned with the prediction of seizure events, whereas the inference of effective brain targets for resective surgery has received surprisingly little attention. In this exploratory pilot study, we describe a distributional clusterin...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.23537

    authors: Steimer A,Müller M,Schindler K

    更新日期:2017-05-01 00:00:00

  • Robust Bayesian estimation of the hemodynamic response function in event-related BOLD fMRI using basic physiological information.

    abstract::In BOLD fMRI data analysis, robust and accurate estimation of the Hemodynamic Response Function (HRF) is still under investigation. Parametric methods assume the shape of the HRF to be known and constant throughout the brain, whereas non-parametric methods mostly rely on artificially increasing the signal-to-noise rat...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.10100

    authors: Marrelec G,Benali H,Ciuciu P,Pélégrini-Issac M,Poline JB

    更新日期:2003-05-01 00:00:00

  • Invariance of firing rate and field potential dynamics to stimulus modulation rate in human auditory cortex.

    abstract::The effect of stimulus modulation rate on the underlying neural activity in human auditory cortex is not clear. Human studies (using both invasive and noninvasive techniques) have demonstrated that at the population level, auditory cortex follows stimulus envelope. Here we examined the effect of stimulus modulation ra...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.21100

    authors: Mukamel R,Nir Y,Harel M,Arieli A,Malach R,Fried I

    更新日期:2011-08-01 00:00:00

  • Altered resting-state connectivity during interictal generalized spike-wave discharges in drug-naïve childhood absence epilepsy.

    abstract:PURPOSE:To investigate the intrinsic brain connections at the time of interictal generalized spike-wave discharges (GSWDs) to understand their mechanism of effect on brain function in untreated childhood absence epilepsy (CAE). METHODS:The EEG-functional MRI (fMRI) was used to measure the resting state functional conn...

    journal_title:Human brain mapping

    pub_type: 杂志文章

    doi:10.1002/hbm.22025

    authors: Yang T,Luo C,Li Q,Guo Z,Liu L,Gong Q,Yao D,Zhou D

    更新日期:2013-08-01 00:00:00