Abstract:
:Reproducibility is one of the most important issues for generalizing the results of clinical research; however, low reproducibility in neuroimaging studies is well known. To overcome this problem, the Enhancing Neuroimaging Genetics through Meta-Analysis (ENIGMA) consortium, an international neuroimaging consortium, established standard protocols for imaging analysis and employs either meta- and mega-analyses of psychiatric disorders with large sample sizes. The Cognitive Genetics Collaborative Research Organization (COCORO) in Japan promotes neurobiological studies in psychiatry and has successfully replicated and extended works of ENIGMA especially for neuroimaging studies. For example, (a) the ENIGMA consortium showed subcortical regional volume alterations in patients with schizophrenia (n = 2,028) compared to controls (n = 2,540) across 15 cohorts using meta-analysis. COCORO replicated the volumetric changes in patients with schizophrenia (n = 884) compared to controls (n = 1,680) using the ENIGMA imaging analysis protocol and mega-analysis. Furthermore, a schizophrenia-specific leftward asymmetry for the pallidum volume was demonstrated; and (b) the ENIGMA consortium identified white matter microstructural alterations in patients with schizophrenia (n = 1,963) compared to controls (n = 2,359) across 29 cohorts. Using the ENIGMA protocol, a study from COCORO showed similar results in patients with schizophrenia (n = 696) compared to controls (n = 1,506) from 12 sites using mega-analysis. Moreover, the COCORO study found that schizophrenia, bipolar disorder (n = 211) and autism spectrum disorder (n = 126), but not major depressive disorder (n = 398), share similar white matter microstructural alterations, compared to controls. Further replication and harmonization of the ENIGMA consortium and COCORO will contribute to the generalization of their research findings.
journal_name
Hum Brain Mappjournal_title
Human brain mappingauthors
Koshiyama D,Miura K,Nemoto K,Okada N,Matsumoto J,Fukunaga M,Hashimoto Rdoi
10.1002/hbm.25040subject
Has Abstractpub_date
2020-06-05 00:00:00eissn
1065-9471issn
1097-0193pub_type
杂志文章,评审abstract::The neurobiological basis of reading is of considerable interest, yet analyzing data from subjects reading words aloud during functional MRI data collection can be difficult. Therefore, many investigators use surrogate tasks such as visual matching or rhyme matching to eliminate the need for spoken output. Use of thes...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22077
更新日期:2013-10-01 00:00:00
abstract::There are two basic types of photoreceptors in the retina: rods and cones. Using a single stimulus viewed at two different light levels, we tested whether input from rods and input from cones are topographically segregated at subsequent levels of human visual cortex. Here we show that rod-mediated visual input produce...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract::Much of the literature exploring differences between intrinsic and task-evoked brain architectures has examined changes in functional connectivity patterns between specific brain regions. While informative, this approach overlooks important overall functional changes in hub organization and network topology that may p...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23500
更新日期:2017-04-01 00:00:00
abstract::Whether neuroimaging findings support discriminable neural correlates of emotion categories is a longstanding controversy. Two recent meta-analyses arrived at opposite conclusions, with one supporting (Vytal and Hamann []: J Cogn Neurosci 22:2864-2885) and the other opposing this proposition (Lindquist et al. []: Beha...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22910
更新日期:2015-10-01 00:00:00
abstract::Population neuroscience endeavours to identify environmental and genetic factors that shape the function and structure of the human brain; it uses tools and knowledge of genetics, epidemiology, and cognitive neuroscience. Here, I focus on the application of population neuroscience in studies of brain development. By d...
journal_title:Human brain mapping
pub_type: 杂志文章,评审
doi:10.1002/hbm.21069
更新日期:2010-06-01 00:00:00
abstract::Gyrification brain abnormalities are considered a marker of early deviations from normal developmental trajectories and a putative predictor of poor outcome in psychiatric disorders. The aim of this study was to explore cortical folding morphology in patients with anorexia nervosa (AN). A MRI brain study was conducted...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22998
更新日期:2015-12-01 00:00:00
abstract::Hypercoupling of activity in speech-perception-specific brain networks has been proposed to play a role in the generation of auditory-verbal hallucinations (AVHs) in schizophrenia; however, it is unclear whether this hypercoupling extends to nonverbal auditory perception. We investigated this by comparing schizophreni...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23934
更新日期:2018-04-01 00:00:00
abstract::Current theories of automatic or preattentive change detection suggest a regularity or prediction violation mechanism involving functional connectivity between the inferior frontal cortex (IFC) and the superior temporal cortex (STC). By disrupting the IFC function with transcranial magnetic stimulation (TMS) and recor...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24984
更新日期:2020-08-01 00:00:00
abstract::We have developed a new L1-norm based generalized minimum norm estimate (GMNE) and have fully characterized the concept of sparseness regularization inherited in the proposed algorithm, which is termed as sparse source imaging (SSI). The new SSI algorithm corrects inaccurate source field modeling in previously reporte...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20448
更新日期:2008-09-01 00:00:00
abstract::Working memory (WM) performance is very often measured using the n-back task, in which the participant is presented with a sequence of stimuli, and required to indicate whether the current stimulus matches the one presented n steps earlier. In this study, we used high-density electroencephalography (hdEEG) coupled to ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.25283
更新日期:2020-11-17 00:00:00
abstract::Infants born prematurely are at increased risk of adverse neurodevelopmental outcome. The measurement of white matter tissue composition and structure can help predict functional performance. Specifically, measurements of myelination and indicators of myelination status in the preterm brain could be predictive of late...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23188
更新日期:2016-07-01 00:00:00
abstract::Previous studies have shown that white matter in the deaf brain changes due to hearing loss. However, how white-matter development is influenced by early hearing experience of deaf people is still unknown. Using diffusion tensor imaging and tract-based spatial statistics, we compared white-matter structures among thre...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21215
更新日期:2012-02-01 00:00:00
abstract::Fine surface texture is best discriminated by touch, in contrast to macro geometric features like shape. We used functional magnetic resonance imaging and a delayed match-to-sample task to investigate the neural substrate for working memory of tactile surface texture. Blindfolded right-handed males encoded the texture...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21500
更新日期:2013-05-01 00:00:00
abstract::Intermittent theta burst stimulation (iTBS) delivered to the dorsolateral prefrontal cortex (DLPFC) has been investigated as a promising treatment for stress and stress-related mental disorders such as major depression, yet large individual differences in responsiveness demand further exploration and optimization of i...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.25193
更新日期:2020-12-15 00:00:00
abstract::Functional imaging studies consistently find that emotional stimuli activate the posterior cingulate cortex, a region that appears to have memory-related functions. However, prior imaging studies have not controlled for non-emotional stimulus features that might activate this region by engaging memory processes unrela...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.10075
更新日期:2003-01-01 00:00:00
abstract::Prior neuroimaging studies support the hypothesis that anticipation, an important component of anxiety, may be mediated by activation within the insular and medial prefrontal cortices including the anterior cingulate cortex. However, there is an insufficient understanding of how affective anticipation differs across a...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21154
更新日期:2011-11-01 00:00:00
abstract::Rasagiline is a monoamine oxidase type B inhibitor that possesses no amphetamine-like properties, and provides symptomatic relief in early and late stages of Parkinson's disease (PD). Data in animal models of PD suggest that chronic administration of rasagiline is associated with structural changes in the substantia n...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23213
更新日期:2016-08-01 00:00:00
abstract::Although elevated serum high-sensitivity C-reactive protein (hsCRP) is related to atherosclerosis, brain infarction, and cognitive decline, it has not been clarified whether increased hsCRP is associated with the decline in brain gray matter volume. Therefore, the purpose of this study was to determine the relationshi...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22073
更新日期:2013-10-01 00:00:00
abstract::The presence of white matter lesions in patients with cerebral small vessel disease (SVD) is among the main causes of cognitive decline. We investigated the relation between white matter hyperintensity (WMH) locations and executive and language abilities in 442 SVD patients without dementia with varying burden of WMH....
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.25273
更新日期:2020-11-24 00:00:00
abstract::A persistent problem in developing plausible neurophysiological models of perception, cognition, and action is the difficulty of characterizing the interactions between different neural systems. Previous studies have approached this problem by estimating causal influences across brain areas activated during cognitive ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20772
更新日期:2009-06-01 00:00:00
abstract::Normal aging is accompanied by an interindividually variable decline in cognitive abilities and brain structure. This variability, in combination with methodical differences and differences in sample characteristics across studies, pose a major challenge for generalizability of results from different studies. Therefor...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.24524
更新日期:2019-06-01 00:00:00
abstract::In daily life, we permanently need to adapt our behavior to new task situations, requiring cognitive control. Such adaptive processes are commonly investigated with the task-switching paradigm. Many fMRI studies have interpreted stronger activation for switch than repeat trials in fronto-parietal brain areas as reflec...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.21234
更新日期:2012-03-01 00:00:00
abstract::Human behavior reflects a continual negotiation of automatic and directed actions. The oculomotor network is a well-characterized neural system in which to study this balance of behavioral control. For instance, saccades made toward and away from a flashed visual stimulus (prosaccades and antisaccades, respectively) a...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20146
更新日期:2005-10-01 00:00:00
abstract::We studied the relationship between muscle activity (electromyography, EMG), force, and brain activity during isometric contractions of the index finger, on a group and individual level. Ten subjects contracted their right or left index finger at 5, 15, 30, 50, and 70% of their maximal force. Subjects received visual ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20388
更新日期:2008-03-01 00:00:00
abstract::Neural dynamics can shape human experience, including pain. Pain has been linked to dynamic functional connectivity within and across brain regions of the dynamic pain connectome (consisting of the ascending nociceptive pathway (Asc), descending antinociceptive pathway (Desc), salience network (SN), and the default mo...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.25245
更新日期:2021-02-15 00:00:00
abstract::A face-selective neural signal is reliably found in humans with functional MRI and event-related potential (ERP) measures, which provide complementary information about the spatial and temporal properties of the neural response. However, because most neuroimaging studies so far have studied ERP and fMRI face-selective...
journal_title:Human brain mapping
pub_type: 杂志文章,随机对照试验
doi:10.1002/hbm.20952
更新日期:2010-10-01 00:00:00
abstract::The amygdala, a small deep brain structure involved in behavioral processing through interactions with other brain regions, has garnered increased attention in recent years in relation to pain processing. As pain is a multidimensional experience that encompasses physical sensation, affect, and cognition, the amygdala ...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.22199
更新日期:2014-02-01 00:00:00
abstract::Functional magnetic resonance imaging (fMRI) studies have shown that neural activity fluctuates spontaneously between different states of global synchronization over a timescale of several seconds. Such fluctuations generate transient states of high and low correlation across distributed cortical areas. It has been hy...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23574
更新日期:2017-06-01 00:00:00
abstract:OBJECTIVE:To assess the structural correlates of cognitive and behavioral impairment in motor neuron diseases (MND) using multimodal MRI. METHODS:One hundred one patients with sporadic MND (56 classic amyotrophic lateral sclerosis, 31 upper motor neuron phenotype, and 14 lower motor neuron phenotype) and 51 controls w...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.23124
更新日期:2016-04-01 00:00:00
abstract::The goal of this study was to determine the linearity of the blood oxygen level-dependent (BOLD) response, as measured by functional magnetic resonance imaging (fMRI), in category-selective regions of human visual cortex. We defined regions of the temporal lobe that were selective to faces (fusiform face area, FFA) an...
journal_title:Human brain mapping
pub_type: 杂志文章
doi:10.1002/hbm.20694
更新日期:2009-08-01 00:00:00