Modeling enzymatic kinetic pathways for ring-opening lactone polymerization.

abstract：:The C-termini of Spidroins produced in the major and minor ampullate glands of spiders are highly conserved. Despite this conservation, no corresponding peptides have been identified in the spinning dopes or the silk filaments so far. To prove their presence or absence, polyclonal antibodies derived against fusion pro...

journal_title：Biomacromolecules

authors： Sponner A,Unger E,Grosse F,Weisshart K

更新日期：2004-05-01 00:00:00

abstract：:Poly(butylene adipate-co-terephthalate) (PBAT) was first chemically modified via free radical grafting with maleic anhydride (MA) and the MA-g-PBAT graft copolymer was then used as a matrix material to obtain cellulose nanocrystal (CNC)-reinforced MA-g-PBAT bionanocomposites via reactive extrusion process to accelerat...

journal_title：Biomacromolecules

authors： Kashani Rahimi S,Aeinehvand R,Kim K,Otaigbe JU

更新日期：2017-07-10 00:00:00

abstract：:A cellulose macromonomer, N-(15-methacryloyloxypentadecanoyl)-tri-O-acetyl-beta-cellulosylamine (CTA-C15-MA (2); M(2)) with number averaged degree of polymerization (DP(n)) = 13), was copolymerized with methyl methacrylate (MMA; M(1)) to give cellulosic copolymer with CTA side chains, PMMA-g-(CTA-C15) (3-A). An absolu...

journal_title：Biomacromolecules

authors： Enomoto-Rogers Y,Kamitakahara H,Takano T,Nakatsubo F

更新日期：2009-08-10 00:00:00

abstract：:In this paper, the contribution of nonpeptido small molecular linkers to the properties of sequence-defined peptidocopolymers was investigated. We synthesized four novel bioinspired peptidocopolymers (P1-P4) based on elastin motif pentapeptide (Gly-Pro-Gly-Gly-Ala) by step growth polymerization. Small molecular linker...

journal_title：Biomacromolecules

authors： Liu Y,Kang Y,Wang J,Wang Z,Chen G,Jiang M

更新日期：2015-12-14 00:00:00

abstract：:Previously, we have shown that the amphiphilic decyl esters of both D- and L-tyrosine (DELT) self-assemble in aqueous solution above their critical micelle concentration values to form long rodlike structures that can be enzymatically polymerized. In the current study, we have examined the self-assembled structures of...

journal_title：Biomacromolecules

authors： Marx KA,Lee JS,Sung C

更新日期：2004-09-01 00:00:00

abstract：:Recently, some attempts have been made to enhance the gas barrier properties of semicrystalline polymers by precisely controlling the arrangement of their impermeable crystalline lamellae. However, it is still a great challenge to achieve regular arrangement of the lamellae along the direction perpendicular to the gas...

journal_title：Biomacromolecules

authors： Bai H,Huang C,Xiu H,Zhang Q,Deng H,Wang K,Chen F,Fu Q

更新日期：2014-04-14 00:00:00

abstract：:Chemo-photodynamic combined therapy is promising in cancer treatment, although low tissue penetration of visible light for activating photosensitizers (e.g., chlorin e6, Ce6) limited its broad applications. Combination of upcoverting nanoparticles (UCNPs) with the photosensitizers endows us with the possibility to uti...

journal_title：Biomacromolecules

authors： Chen Y,Ren J,Tian D,Li Y,Jiang H,Zhu J

更新日期：2019-10-14 00:00:00

abstract：:Restorative medicine has a constant need for improved scaffold materials. Degradable biopolymers often suffer from uncontrolled chemical or enzymatic hydrolysis by the host. The need for a second surgery on the other hand is a major drawback for nondegradable scaffold materials. In this paper we report the design and ...

journal_title：Biomacromolecules

authors： Berski S,van Bergeijk J,Schwarzer D,Stark Y,Kasper C,Scheper T,Grothe C,Gerardy-Schahn R,Kirschning A,Dräger G

更新日期：2008-09-01 00:00:00

abstract：:Electrochemically controlled, reversible assembly of biopolymers into hydrogel structures is a promising technique for on-demand cell or drug encapsulation and release systems. An electrochemically sol-gel transition has been demonstrated in regenerated Bombyx mori silk fibroin, offering a controllable way to generate...

journal_title：Biomacromolecules

authors： Lin Y,Xia X,Shang K,Elia R,Huang W,Cebe P,Leisk G,Omenetto F,Kaplan DL

更新日期：2013-08-12 00:00:00

abstract：:Aberrant expression of histone deacetylases (HDACs) is related to various types of cancer and is associated with increased proliferation of tumor cells. Hence, the detection of HDAC activities is of great significance for medical sciences as well as biological diagnostics. Herein, we report a hyperbranched polyester-b...

journal_title：Biomacromolecules

authors： Yu C,Wu Y,Zeng F,Li X,Shi J,Wu S

更新日期：2013-12-09 00:00:00

abstract：:The leading cause of death in the United States is cardiovascular disease. The majority of these cases result from heart failure post-myocardial infarction (MI). We present data providing evidence for use of acetalated dextran (AcDex) microparticles as a delivery vehicle for therapeutics to the heart post-MI. We harne...

journal_title：Biomacromolecules

authors： Suarez S,Grover GN,Braden RL,Christman KL,Almutairi A

更新日期：2013-11-11 00:00:00

abstract：:Many polymers, including polyethylene, feature a relatively low melting point and hence must be cross-linked to make them viable for applications that demand a high stiffness and creep resistance at elevated temperatures. The resulting thermoset plastics cannot be recycled, and therefore alternative materials with a r...

journal_title：Biomacromolecules

authors： Peterson A,Östergren I,Lotsari A,Venkatesh A,Thunberg J,Ström A,Rojas R,Andersson M,Berglund LA,Boldizar A,Müller C

更新日期：2019-10-14 00:00:00

abstract：:Marine mussels tether to seashore surfaces with byssal threads, proteinaceous fibers that effectively dissipate energy from crashing waves. Protein-metal coordination bonds have been proposed to contribute to the characteristic mechanical and self-healing properties of byssal threads; however, very little is understoo...

journal_title：Biomacromolecules

authors： Schmitt CN,Politi Y,Reinecke A,Harrington MJ

更新日期：2015-09-14 00:00:00

abstract：:The determination of the collagen and glycosaminoglycan (GAG) contents of native and particularly bioengineered tissues is of considerable interest because the collagen-to-GAG ratio determines the water content of the tissue, which is crucial regarding its mechanical properties. (1)H NMR spectroscopy subsequent to the...

journal_title：Biomacromolecules

authors： Riemer T,Nimptsch A,Nimptsch K,Schiller J

更新日期：2012-07-09 00:00:00

abstract：:Angiogenesis has long been a desired therapeutic approach to improve clinical outcomes of conditions typified by ischemia. Vascular endothelial growth factor (VEGF) has demonstrated the ability to generate new blood vessels in vivo, but trials using intravenous delivery have not yet produced clinical success. Localize...

journal_title：Biomacromolecules

authors： Huang M,Vitharana SN,Peek LJ,Coop T,Berkland C

更新日期：2007-05-01 00:00:00

abstract：:The structure of an extracellular polysaccharide (EPS) from Streptococcus thermophilus THS has been determined. A combination of component analysis, methylation analysis and NMR spectroscopy shows that the polysaccharide is composed of pentasaccharide repeating units. Sequential information was obtained by two-dimensi...

journal_title：Biomacromolecules

authors： Nordmark EL,Yang Z,Huttunen E,Widmalm G

更新日期：2005-01-01 00:00:00

abstract：:A His-tagged coiled coil stem loop peptide with stable secondary structure was designed and biosynthesized. A series of oligopeptides related to the EBV envelope glycoprotein 350/220 N-terminal nonapeptide as potential CD21 receptor-binding epitopes were engineered into the loop region of the peptide scaffold. It was ...

journal_title：Biomacromolecules

authors： Tang A,Kopecek J

更新日期：2002-05-01 00:00:00

abstract：:Biodegradable aliphatic polyesters such as poly(lactide) and poly(ε-caprolactone), largely used in tissue engineering applications, lack suitable functional groups and biological cues to enable interactions with cells. Because of the ubiquity of thiol groups in the biological environment and the pliability of thiol ch...

journal_title：Biomacromolecules

authors： Fuoco T,Finne-Wistrand A,Pappalardo D

更新日期：2016-04-11 00:00:00

abstract：:The synthesis of biocompatible, thermo-responsive ABA triblock copolymers in which the outer A blocks comprise poly(N-isopropylacrylamide) and the central B block is poly(2-methacryloyloxyethyl phosphorylcholine) is achieved using atom transfer radical polymerization with a commercially available bifunctional initiato...

journal_title：Biomacromolecules

authors： Li C,Tang Y,Armes SP,Morris CJ,Rose SF,Lloyd AW,Lewis AL

更新日期：2005-03-01 00:00:00

abstract：:Enzymatic hydrolysis of selected copolymers of cellulose diacetate-graft-poly(L-lactide)s (CDA-g-PLLAs) were conducted with proteinase K for film specimens, which were solely quenched from the molten state or, further, annealed at temperatures below or above their glass transition temperatures. The hydrolysis rates de...

journal_title：Biomacromolecules

authors： Teramoto Y,Nishio Y

更新日期：2004-03-01 00:00:00

abstract：:Repifermin, a truncated form of fibroblast growth factor-10 (FGF-10) also known as keratinocyte growth factor-2 (KGF-2), is a heparin-binding protein with potent regenerative properties. The protein unfolds and aggregates at relatively low temperature (~37 °C). Electrostatic interactions between polyanions and several...

journal_title：Biomacromolecules

authors： Khondee S,Olsen CM,Zeng Y,Middaugh CR,Berkland C

更新日期：2011-11-14 00:00:00

abstract：:RNA-based delivery system for cancer therapy remains a challenge. In this study, a stearyl-peptide (SHR) was synthesized using arginine, histidine, cysteine, and stearyl moieties. Further, the stearyl-peptides were cross-linked by disulfide bonds to obtain cross-linked polypeptides (SHRss) with different molecular wei...

journal_title：Biomacromolecules

authors： Tai Z,Wang X,Tian J,Gao Y,Zhang L,Yao C,Wu X,Zhang W,Zhu Q,Gao S

更新日期：2015-04-13 00:00:00

abstract：:For developing broader application of biobased polymers, graft copolymers and comb polymers having poly(lactic acid) (PLA) side chains have been synthesized by using a macromonomer technique. PLA macromonomers (MMm) having a methacryloyl polymerizable group with different PLA chain length with an average length m = 4,...

journal_title：Biomacromolecules

authors： Ishimoto K,Arimoto M,Okuda T,Yamaguchi S,Aso Y,Ohara H,Kobayashi S,Ishii M,Morita K,Yamashita H,Yabuuchi N

更新日期：2012-11-12 00:00:00

abstract：:New aspects concerning the mechanism of formation of chitosan physical hydrogels without any cross-linking agent were studied. The gelation took place during the evaporation of a hydroalcoholic solution of chitosan. We first demonstrated that it was possible to form a physical hydrogel from a hydrochloride form of chi...

journal_title：Biomacromolecules

authors： Boucard N,Viton C,Domard A

更新日期：2005-11-01 00:00:00

abstract：:The aim of this paper is to define optimal conditions for the extraction of chitin from shrimp shells. The kinetics of both demineralization and deproteinization with, in the latter case, the role of temperature are studied. The characterization of the residual calcium and protein contents, the molecular weights, and ...

journal_title：Biomacromolecules

authors： Percot A,Viton C,Domard A

更新日期：2003-01-01 00:00:00

abstract：:Weissella confusa VTT E-90392 is an efficient producer of a dextran that is mainly composed of α-(1→6)-linked D-glucosyl units and very few α-(1→3) branch linkages. A mixture of the Chaetomium erraticum endodextranase and the Aspergillus niger α-glucosidase was used to hydrolyze W. confusa dextran to glucose and a set...

journal_title：Biomacromolecules

authors： Maina NH,Virkki L,Pynnönen H,Maaheimo H,Tenkanen M

更新日期：2011-02-14 00:00:00

abstract：:The ability to adopt at least two different stable conformations is a common feature of proteins involved in many neurodegenerative diseases. The involved molecules undergo a conformational transition from native, mainly helical states to insoluble amyloid structures that have high β-sheet content. A detailed characte...

journal_title：Biomacromolecules

authors： Gerling UI,Brandenburg E,von Berlepsch H,Pagel K,Koksch B

更新日期：2011-08-08 00:00:00

abstract：:The mycobacterial cell wall is extraordinarily thick and tight consisting mainly of (1). long chain fatty acids, the mycolic acids, and (2). a unique polysaccharide, arabinogalactan (AG). These two chemical constituents are covalently linked through ester bonds. Minnikin (The Biology of the Mycobacteria; Academic: Lon...

journal_title：Biomacromolecules

authors： Hong X,Hopfinger AJ

更新日期：2004-05-01 00:00:00

abstract：:Tumorigenic cell behaviors can be suppressed or enhanced by their physicochemical environment. As a first step toward developing materials that allow tumorigenic behaviors to be observed and manipulated, we cultured related MCF10 breast cell lines on fibers composed of the Drosophila protein Ultrabithorax (Ubx). These...

journal_title：Biomacromolecules

authors： Hsiao HC,Santos A,Howell DW,Patterson JL,Fuchs-Young RS,Bondos SE

更新日期：2016-11-14 00:00:00

abstract：:Cellulose-based dendrimerized material was prepared and its quality was assessed by determining the number of amine functional groups incorporated. Based on the results for a series of preparations, the material was obtained in a highly reproducible manner thanks to the particular chemical construction method used. Th...

journal_title：Biomacromolecules

authors： Montañez MI,Perez-Inestrosa E,Suau R,Mayorga C,Torres MJ,Blanca M

更新日期：2008-05-01 00:00:00