A Route to Aliphatic Poly(ester)s with Thiol Pendant Groups: From Monomer Design to Editable Porous Scaffolds.

abstract：:meso-Tetra(N-methyl-4-pyridyl) porphine tetra tosylate (TMP) is a photosensitizer that can be used in photodynamic therapy (PDT) to induce cell death through generation of reactive oxygen species in targeted tumor cells. However, TMP is highly hydrophilic, and therefore, its ability to accumulate intracellularly is li...

journal_title：Biomacromolecules

authors： Abdelghany SM,Schmid D,Deacon J,Jaworski J,Fay F,McLaughlin KM,Gormley JA,Burrows JF,Longley DB,Donnelly RF,Scott CJ

更新日期：2013-02-11 00:00:00

abstract：:As a first step toward utilizing self-assembling peptide scaffolds to create tunable matrices for drug delivery, peptide RADAFI and RADAFII, containing the same amino acid composition but different positions of one phenylalanine residue, scaffolds were prepared for controlled release of chiral enantiomers. The release...

journal_title：Biomacromolecules

authors： Zhao Y,Tanaka M,Kinoshita T,Higuchi M,Tan T

更新日期：2009-12-14 00:00:00

abstract：:Gene therapy is rapidly regaining traction in terms of research activity and investment across the globe, with clear potential to revolutionize medicine and tissue regeneration. Viral vectors remain the most commonly utilized gene delivery vehicles, due to their high efficiency, however, they are acknowledged to have ...

journal_title：Biomacromolecules

authors： Wong LY,Xia B,Wolvetang E,Cooper-White J

更新日期：2018-02-12 00:00:00

abstract：:PLGA nanoparticles are among the most studied polymer nanoformulations for several drugs against different kinds of malignant diseases, thanks to their in vivo stability and tumor localization exploiting the well-documented "enhanced permeation and retention" (EPR) effect. In this paper, we have developed uniform curc...

journal_title：Biomacromolecules

authors： Verderio P,Bonetti P,Colombo M,Pandolfi L,Prosperi D

更新日期：2013-03-11 00:00:00

abstract：:The molecular recognition features of a DNA-sensitive fluorescent bioconjugate capable of targeting a specific DNA sequence with high efficiency are described. The bioconjugate combines a polypeptide from the Tc3 transposase DNA-binding domain with the dsDNA-sensitive fluorophore thiazole orange. Fluorescence spectros...

journal_title：Biomacromolecules

authors： Thompson M

更新日期：2007-11-01 00:00:00

abstract：:The structure of an extracellular polysaccharide (EPS) from Streptococcus thermophilus THS has been determined. A combination of component analysis, methylation analysis and NMR spectroscopy shows that the polysaccharide is composed of pentasaccharide repeating units. Sequential information was obtained by two-dimensi...

journal_title：Biomacromolecules

authors： Nordmark EL,Yang Z,Huttunen E,Widmalm G

更新日期：2005-01-01 00:00:00

abstract：:Immobilizing zwitterionic molecules on material surfaces has been a promising strategy for creating antifouling surfaces. Herein, we show the ability to surface derivatize an allyl-ether-functionalized thermoplastic polyurethane (TPU) with a zwitterionic thiol in a radically induced thiol-ene reaction. The thermoplast...

journal_title：Biomacromolecules

authors： Nikam SP,Chen P,Nettleton K,Hsu YH,Becker ML

更新日期：2020-07-13 00:00:00

abstract：:Solid films of deoxyribonucleic acid (DNA) containing a hydrated ionic liquid, choline dihydrogen phosphate (CDP), were prepared by a solvent-casting method. Thermal properties, aggregation structure, thermal molecular motion, and tensile properties of CDP-containing DNA films were examined by thermogravimetry (TG), w...

journal_title：Biomacromolecules

authors： Morimitsu Y,Matsuno H,Ohta N,Sekiguchi H,Takahara A,Tanaka K

更新日期：2020-02-10 00:00:00

abstract：:Oxidative coupling of phenol-containing precursor poly(amino acid)s, poly(alpha-glutamine), poly(alpha/beta-asparagine), and poly(gamma-glutamine) derivatives, has been examined to produce a new class of soluble poly(amino acid)s. Under appropriate reaction conditions, the Fe-salen and HRP catalysts efficiently induce...

journal_title：Biomacromolecules

authors： Fukuoka T,Uyama H,Kobayashi S

更新日期：2004-05-01 00:00:00

abstract：:Chitosan fibers showing narrow diameter distribution with a mean of 42 nm were produced by electrospinning and utilized for the sorption of Fe(III), Cu(II), Ag(I), and Cd(II) ions from aqueous solutions. The ion concentrations in the supernatant solutions were determined using inductively coupled plasma-mass spectrome...

journal_title：Biomacromolecules

authors： Horzum N,Boyaci E,Eroğlu AE,Shahwan T,Demir MM

更新日期：2010-12-13 00:00:00

abstract：:As an aim toward developing biologically mimetic and functional nanofiber-based tissue engineering scaffolds, we demonstrated the encapsulation of a model protein, fluorescein isothiocyanate-conjugated bovine serum albumin (fitcBSA), along with a water-soluble polymer, poly(ethylene glycol) (PEG), within the biodegrad...

journal_title：Biomacromolecules

authors： Zhang YZ,Wang X,Feng Y,Li J,Lim CT,Ramakrishna S

更新日期：2006-04-01 00:00:00

abstract：:Exendin-4 (EX4), a glucagon-like peptide-1 receptor (GLP-1R) agonist that regulates blood glucose levels, has been used in the management of type-2 diabetes mellitus. EX4 can be PEGylated to improve its antidiabetic effects by enhancing its stability and extending the circulation half-life. Here, to determine whether ...

journal_title：Biomacromolecules

authors： Lee W,Park EJ,Kwak S,Lee KC,Na DH,Bae JS

更新日期：2016-03-14 00:00:00

abstract：:There is a lack of hydrogel materials whose properties can be tuned at the point of use. Biological hydrogels, such as collagen, gelate at physiological temperatures; however, they are not always ideal as scaffolds because of their low mechanical strength. Their mechanics can be improved through cross-linking and chem...

journal_title：Biomacromolecules

authors： Barnes AL,Genever PG,Rimmer S,Coles MC

更新日期：2016-03-14 00:00:00

abstract：:Native cellulose consists of a set of parallel chains composed of glucose. Most of the time, these chains are highly ordered and form a structure that is known as a microfibril. On the other hand, highly crystalline forms of cellulose are more difficult to process and often are unpredictable in their behavior. If an o...

journal_title：Biomacromolecules

authors： Kondo T,Togawa E,Brown RM Jr

更新日期：2001-01-01 00:00:00

abstract：:The purpose of this study is to investigate the combined effects of oxygen plasma treatments and silver nanoparticles (Ag) on PLGA in order to modulate the surface antimicrobial properties through tunable bacteria adhesion mechanisms. PLGA nanocomposite films, produced by solvent casting with 1 wt % and 7 wt % of Ag n...

journal_title：Biomacromolecules

authors： Fortunati E,Mattioli S,Visai L,Imbriani M,Fierro JL,Kenny JM,Armentano I

更新日期：2013-03-11 00:00:00

abstract：:Electrically conducting polymeric membranes were prepared by incorporating multiwalled carbon nanotubes (MWCNTs) into bacterial cellulose pellicles produced by Gluconacetobacter xylinum. The MWCNTs were dispersed in a surfactant (cationic cetyl trimethylammonium bromide) solution, and cellulose pellicles were dipped i...

journal_title：Biomacromolecules

authors： Yoon SH,Jin HJ,Kook MC,Pyun YR

更新日期：2006-04-01 00:00:00

abstract：:The formation of amylose-polystyrene inclusion complexes via a novel two-step approach is described. In the first-step, styrene was inserted inside the amylose helical cavity, followed by free radical polymerization in the second step. The inclusion complexes were characterized by attenuated total reflection fourier t...

journal_title：Biomacromolecules

authors： Kumar K,Woortman AJ,Loos K

更新日期：2013-06-10 00:00:00

abstract：:The electrospinning of polymer melts can offer an advantage over solution electrospinning, in the development of layered tissue constructs for tissue engineering. Melt electrospinning does not require a solvent, of which many are cytotoxic in nature, and the use of nonwater soluble polymers allows the collection of fi...

journal_title：Biomacromolecules

authors： Dalton PD,Klinkhammer K,Salber J,Klee D,Möller M

更新日期：2006-03-01 00:00:00

abstract：:Ephemeral gels, called Enzgels, successively undergo sol-gel and then gel-sol transition under the action of two antagonistic enzymes, transglutaminase and protease. Molecular and macroscopic properties of Enzgels are directly dependent on the enzymatic activities and their ratios. This work studies the characteristic...

journal_title：Biomacromolecules

authors： Picard J,Giraudier S,Larreta-Garde V

更新日期：2008-01-01 00:00:00

abstract：:This study is devoted to developing amphiphilic block polymers based on phenylborate ester, which can self-assemble to form nanoparticles, as a glucose-sensitive drug carrier. Poly(ethylene glycol)-block-poly[(2-phenylboronic esters-1,3-dioxane-5-ethyl) methylacrylate] (MPEG5000-block-PBDEMA) was fabricated with MPEG5...

journal_title：Biomacromolecules

authors： Yao Y,Zhao L,Yang J,Yang J

更新日期：2012-06-11 00:00:00

abstract：:Hydrophobic methacrylic monomers were polymerized in aqueous media using methylated (1.8)-beta-cyclodextrin (MeCD) additives. Hydrophobic monomers tert-butyl methacrylate (tBuMA), cyclohexyl methacrylate (CMA), and 2-ethylhexyl methacrylate (2EHMA) were each dissolved in chloroform with MeCD. Chloroform was then evapo...

journal_title：Biomacromolecules

authors： Madison PH,Long TE

更新日期：2000-01-01 00:00:00

abstract：:Orb-weaving spider silk fibers are assembled from very large, highly repetitive proteins. The repeated segments contain, in turn, short, simple, and repetitive amino acid motifs that account for the physical and mechanical properties of the assembled fiber. Of the six orb-weaver silk fibroins, the piriform silk that m...

journal_title：Biomacromolecules

authors： Perry DJ,Bittencourt D,Siltberg-Liberles J,Rech EL,Lewis RV

更新日期：2010-11-08 00:00:00

abstract：:Thermoresponsive polymers with lower critical solution temperatures (LCSTs) are of significant interest for a wide range of applications from sensors to drug delivery vehicles. However, the most widely investigated LCST polymers have nondegradable backbones, limiting their applications in vivo or in the environment. D...

journal_title：Biomacromolecules

authors： Rabiee Kenaree A,Sirianni QEA,Classen K,Gillies ER

更新日期：2020-09-14 00:00:00

abstract：:This article reports on the successful preparation and characterization of cellulose nanocrystals (CNCs) surface-modified with polylactide (PLA) and poly(butylene succinate) (PBS) binary mixed homopolymer brushes. Their synthesis was designed as a three-step procedure combining polyester synthesis and surface-modifica...

journal_title：Biomacromolecules

authors： Mincheva R,Jasmani L,Josse T,Paint Y,Raquez JM,Gerbaux P,Eyley S,Thielemans W,Dubois P

更新日期：2016-09-12 00:00:00

abstract：:Single-molecule measurements of the interaction of leukocyte function-associated antigen-1 (LFA-1), expressed on Jurkat T cells, with intercellular adhesion molecules-1 and -2 (ICAM-1 and ICAM-2) were conducted using atomic force microscopy (AFM). The force spectra (i.e., unbinding force versus loading rate) of both t...

journal_title：Biomacromolecules

authors： Wojcikiewicz EP,Abdulreda MH,Zhang X,Moy VT

更新日期：2006-11-01 00:00:00

abstract：:Silkworm silk has excellent mechanical properties, biocompatibility, and promising applications in the biomedical sector. Silkworms spin silk at the beginning and end of each of their five instar stages, as well as spinning mature silk after the fifth instar. We evaluated the mechanical properties and structure of 10 ...

journal_title：Biomacromolecules

authors： Peng Z,Yang X,Liu C,Dong Z,Wang F,Wang X,Hu W,Zhang X,Zhao P,Xia Q

更新日期：2019-03-11 00:00:00

abstract：:Utilization of reversible interactions as sacrificial bonds in biopolymers is critical for the integral synthesis of mechanically superior biological materials. In this work, cellulose nanofibrils (CNFs) reinforced covalent polyacrylamide (PAAm) composite hydrogels are immersed into multivalent cation (Ca2+, Zn2+, Al3...

journal_title：Biomacromolecules

authors： Yang J,Xu F,Han CR

更新日期：2017-03-13 00:00:00

abstract：:In this paper we report on protein refolding by means of a liquid-liquid transfer technique using a calixarene. We have found that a calix[6]areneacetic acid derivative forms a supramolecular complex with urea-denatured cytochrome c at the oil-water interface, which enables quantitative transfer of the protein from an...

journal_title：Biomacromolecules

authors： Shimojo K,Oshima T,Naganawa H,Goto M

更新日期：2007-10-01 00:00:00

abstract：:Hydrogel scaffolds are used in biomedicine to study cell differentiation and tissue evolution, where it is critical to control the delivery of chemical cues both spatially and temporally. While large molecules can be physically entrapped in a hydrogel, moderate molecular weight therapeutics must be tethered to the hyd...

journal_title：Biomacromolecules

authors： Griffin DR,Schlosser JL,Lam SF,Nguyen TH,Maynard HD,Kasko AM

更新日期：2013-04-08 00:00:00

abstract：:Hydrogels are attracting increasing attention due to their potential use in various fields. However, most of the existing hydrogels have limitations in either dissipating mechanical energy or maintaining high stretchability under deformation, thus do not possess high mechanical properties. Herein, poly(vinyl alcohol) ...

journal_title：Biomacromolecules

authors： Chen W,Li N,Ma Y,Minus ML,Benson K,Lu X,Wang X,Ling X,Zhu H

更新日期：2019-12-09 00:00:00