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Polycystic ovary syndrome is associated with negatively variable impacts on domains of health-related quality of life: evidence from a meta-analysis.

Abstract：

OBJECTIVE:To systematically review the literature to identify the impact of polycystic ovary syndrome (PCOS) on specific health-related quality of life domains. DESIGN:Meta-analysis. SETTING:N/A. PATIENT(S):The outcomes of 423 patients and 285 controls from 5 articles that used the Short Form 36 (SF-36) questionnaire were used for meta-analysis. INTERVENTION(S):N/A. MAIN OUTCOME MEASURE(S):The SF-36 dimensions including physical function, physical role function, body pain, general health, vitality, social function, emotional role function, and mental health were evaluated. RESULT(S):Compared with controls, women with PCOS had lower scores in all SF-36 dimensions: physical function (mean differences [MD], -5.46; 95% confidence intervals [CI], -8.52, -2.41), physical role function (MD, -5.76; 95% CI, -8.49, -3.03), body pain (MD, -4.55; 95% CI, -7.99, -1.11), general health (MD, -11.34; 95% CI, -19.53, -3.15), vitality (MD, -15.14; 95% CI, -17.43, -12.84), social function (MD, -15.95, 95% CI, -18.57, -13.33), emotional role function (MD, -23.86; 95% CI, -27.51, -20.21), and mental health (MD, -13.83; 95% CI, -16.13, -11.53). CONCLUSION(S):The meta-analysis showed that women with PCOS score lower in each dimension of the SF-36, mostly in the emotional role function.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Li Y,Li Y,Yu Ng EH,Stener-Victorin E,Hou L,Wu T,Han F,Wu X

doi

10.1016/j.fertnstert.2011.05.072

subject

Has Abstract

pub_date

2011-08-01 00:00:00

pages

452-8

issue

2

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(11)00857-0

journal_volume

96

pub_type

杂志文章,meta分析,评审

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