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The feasibility of assessing women's perceptions of the risks and benefits of fertility drug therapy in relation to ovarian cancer risk.

Abstract：

OBJECTIVE:To determine the feasibility of asking women undergoing fertility treatment the maximum increased risk of ovarian cancer they would be willing to tolerate in order to take ovulation-induction drugs. DESIGN:A prospective pilot study of women attending fertility clinics over a 2-month period. SETTING:Two tertiary care fertility clinics in Toronto. PATIENT(S):Sixty-one English-speaking women were approached and 85% (n = 52) were enrolled. INTERVENTION(S):A self-administered questionnaire with fertility-specific questions. Thirty-eight women also were asked to complete standardized scales of anxiety and optimism. MAIN OUTCOME MEASURE(S):Women's report of the maximum level of lifetime risk of ovarian cancer they were willing to tolerate in order to undergo fertility treatment. RESULT(S):Seventy-nine percent were willing to accept an increased risk of ovarian cancer. Only 24% understood that treatment for ovarian cancer usually was not curative. CONCLUSION(S):A majority of patients were willing to tolerate a modest increase in their lifetime risk of ovarian cancer because of fertility treatment, most basing their estimate of acceptable risk on limited awareness of the issue.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Rosen B,Irvine J,Ritvo P,Shapiro H,Stewart D,Reynolds K,Robinson G,Thomas J,Neuman J,Murphy J

doi

10.1016/s0015-0282(97)81481-1

subject

Has Abstract

pub_date

1997-07-01 00:00:00

pages

90-4

issue

1

eissn

0015-0282

issn

1556-5653

pii

S0015028297814811

journal_volume

68

pub_type

杂志文章

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