Korean ginseng induces spermatogenesis in rats through the activation of cAMP-responsive element modulator (CREM).

Abstract:

:The effect of Korean ginseng (ginseng) on spermatogenesis and cAMP-responsive element modulator (CREM) in rat testes was evaluated using sperm analysis, reverse transcription polymerase chain reaction, and Western blot analysis. The ginseng-treated rats exhibited significantly increased sperm count and motility with enhanced levels of CREM messenger RNA and protein. Ginseng appears to induce spermatogenesis via CREM activation in rat testes.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Park WS,Shin DY,Kim DR,Yang WM,Chang MS,Park SK

doi

10.1016/j.fertnstert.2006.12.014

subject

Has Abstract

pub_date

2007-10-01 00:00:00

pages

1000-2

issue

4

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(07)00039-8

journal_volume

88

pub_type

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