Sudden cardiac death in patients with chronic kidney disease: prevention is the sine qua non.

abstract：BACKGROUND/AIMS:Excessive phosphate concentrations trigger vascular calcification, an active process promoted by osteoinduction of vascular smooth muscle cells (VSMCs) with increased expression and activity of transcription factor RUNX2 (Core-binding factor α1, CBFA1), alkaline phosphatase (ALPL), TGFß1, transcription ...

journal_title：Kidney & blood pressure research

authors： Alesutan I,Musculus K,Castor T,Alzoubi K,Voelkl J,Lang F

更新日期：2015-01-01 00:00:00

abstract：:Glomerulosclerosis and tubulointerstitial fibrosis are the hallmarks of chronic renal diseases. In the present study, we have investigated the potential involvement of various proteinases in these alterations in the model of puromycin aminonucleoside (PAN) nephrosis. Two groups of male Wistar rats were given either th...

journal_title：Kidney & blood pressure research

authors： Huang S,Schaefer RM,Reisch S,Paczek L,Schaefer L,Teschner M,Sebekova K,Heidland A

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:Though the association between microalbuminuria (MA) and inflammatory markers has been studied, the possible gender differences in these associations have not yet been analyzed. Our study aims to analyze the role of gender in the associations of MA and inflammatory markers. METHODS:1,060 hypertensive patien...

journal_title：Kidney & blood pressure research

authors： Shantha GP,Kumar AA,Bharadhi MK,Arthur P

更新日期：2009-01-01 00:00:00

abstract：UNLABELLED:Anaemia is frequently found in patients with chronic heart failure (CHF) and has been associated with an increase in mortality and morbidity, impaired cardiac and renal function and a reduced quality of life (QoL) compared with non-anaemic CHF patients. Correction of anaemia with recombinant human erythropoi...

journal_title：Kidney & blood pressure research

authors： Silverberg DS,Wexler D,Blum M,Iaina A,Sheps D,Keren G,Scherhag A,Schwartz D

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND/AIMS:The kinases SPAK (SPS1-related proline/alanine-rich kinase) and OSR1 (oxidative stress-responsive kinase 1) participate in the regulation of the NaCl cotransporter NCC and the Na+, K+, 2Cl- cotransporter NKCC2. The kinases are regulated by WNK (with-no-K[Lys]) kinases. Mutations of genes encoding WNK ki...

journal_title：Kidney & blood pressure research

authors： Elvira B,Munoz C,Borras J,Chen H,Warsi J,Ajay SS,Shumilina E,Lang F

更新日期：2014-01-01 00:00:00

abstract：:The value of neutrophil-gelatinase-associated lipocalin (NGAL) was highlighted as a novel biomarker for the detection of acute renal failure. We tested the hypothesis whether NGAL could represent an early biomarker of contrast-induced nephropathy (CIN) in 100 patients with normal serum creatinine values undergoing per...

journal_title：Kidney & blood pressure research

authors： Bachorzewska-Gajewska H,Malyszko J,Sitniewska E,Malyszko JS,Pawlak K,Mysliwiec M,Lawnicki S,Szmitkowski M,Dobrzycki S

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:In the Chronic REnal Disease in Turkey-CREDIT Study, a large populationbased study on 10,748 adults, the prevalence of chronic kidney disease (CKD) and relationship between CKD and other cardiovascular risk factors had been studied. METHODS:This report presents the results of CREDIT study on the prevalence,...

journal_title：Kidney & blood pressure research

authors： Altun B,Süleymanlar G,Utaş C,Arınsoy T,Ateş K,Ecder T,Camsarı T,Serdengeçti K

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Studies have demonstrated that cholesterol variability is an independent predictor of cerebrovascular and cardiovascular events. OBJECTIVE:This study aimed to investigate the association of visit-to-visit variability in total cholesterol (TC) with kidney decline in a Chinese community-based population. MET...

journal_title：Kidney & blood pressure research

authors： Yan Y,Huang Y,Zhou D,Tang S,Feng YQ

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND/AIMS:We have reported that the long-term administration of angiotensin II receptor blockers (ARBs) induced unusual proliferative changes of renal afferent arteriolar smooth muscle cells (SMCs) in rats, associated with the overproduction of renin. In this study, we examined that a direct renin inhibitor (DRI:...

journal_title：Kidney & blood pressure research

authors： Nagai Y,Nakanishi K,Yamanaka N

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND/AIMS:The metabolic syndrome (MetS), as assessed using dichotomous criteria, is associated with increased risk of future chronic kidney disease (CKD), though this relationship is unclear among African Americans, who have lower risk for MetS but higher risk for CKD. METHODS:We performed logistic regression us...

journal_title：Kidney & blood pressure research

authors： DeBoer MD,Filipp SL,Musani SK,Sims M,Okusa MD,Gurka M

更新日期：2018-01-01 00:00:00

abstract：:The aim of this study was to investigate whether the renoprotective effect of angiotensin-converting enzyme inhibitors (ACEIs) following 5/6 renal mass reduction is due in part to the potentiation of kinins. Three groups of rats with 5/6 renal mass reduction were studied during the 14 weeks following surgery. One grou...

journal_title：Kidney & blood pressure research

authors： MacLaughlin M,Monserrat AJ,Muller A,Matoso M,Amorena C

更新日期：1998-01-01 00:00:00

abstract：AIMS AND METHODS:Our aim was to evaluate the antihypertensive efficacy and tolerability of angiotensin II type 1 (AT1) receptor antagonists. Valsartan or candesartan cilexetil was administered to 11 dialysis patients with elevated blood pressure. The patients (6 male, 5 female; mean age +/- SD 61+/-11 years) were on re...

journal_title：Kidney & blood pressure research

authors： Tepel M,van der Giet M,Zidek W

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND/AIMS:Ischemia/reperfusion (I/R) is the most common cause of acute renal injury. I/R-induced oxidative stress is involved in the development of acute renal injury, which can be reversed by supplementation with L-arginine, a precursor of nitric oxide (NO). This study was conducted to evaluate alterations in th...

journal_title：Kidney & blood pressure research

authors： Tong F,Zhou X

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Treatment with angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin 2 receptor blockers (ARBs) is associated with an increased risk for acute kidney injury after cardiovascular interventions. However, for patients undergoing kidney biopsy, no data is available. METHODS:Four hundred and sixty-six ...

journal_title：Kidney & blood pressure research

authors： Friedl A,Peric S,Masghati S,Wolzt M,Hörl WH,Soleiman A,Fuhrmann V,Haider DG

更新日期：2012-01-01 00:00:00

abstract：:In the failing heart, the local angiotensin II concentration is increased, and the extent of cardiac angiotensin II release is related to the clinical signs of heart failure. The enzymes involved in myocardial generation of angiotensin II are the angiotensin-converting enzyme (ACE) and chymases. While myocardial angio...

journal_title：Kidney & blood pressure research

authors： Schulz R,Heusch G

更新日期：2005-01-01 00:00:00

abstract：:The effects on glomerular hemodynamics of angiotensin-converting enzyme (ACE) inhibition with captopril and of angiotensin II receptor blockade with EXP 3174, an active metabolite of losartan, either alone or in combination, were compared in anesthetized dogs. Administration of EXP 3174 intrarenally led to an increase...

journal_title：Kidney & blood pressure research

authors： Heller J,Kramer HJ,Horácek V

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND/AIM:Serum gamma-glutamyltransferase (GGT), a biomarker of oxidative stress, is associated with an increased risk of diabetes and hypertension. However, it is not known whether higher serum GGT is independently associated with chronic kidney disease (CKD). Therefore, we examined the association between serum ...

journal_title：Kidney & blood pressure research

authors： Teppala S,Shankar A,Li J,Wong TY,Ducatman A

更新日期：2010-01-01 00:00:00

abstract：:Acute kidney injury (AKI) is a complex kidney disorder that leads to numerous complications, such as elevated nitrogenous wastes, metabolic acidosis, high potassium levels and even death. The pathogenesis of AKI is very complicated, and its causes are commonly categorized as prerenal, intrinsic or postrenal. In the pa...

journal_title：Kidney & blood pressure research

authors： Zhou P,Chen Z,Zou Y,Wan X

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:The biological properties of oxidized and non-oxidized PTH are substantially different. Oxidized PTH (oxPTH) loses its PTH receptor-stimulating properties, whereas non-oxidized PTH (n-oxPTH) is a full agonist of the receptor. This was described in more than 20 well published studies in the 1970(s) and 80(s)....

journal_title：Kidney & blood pressure research

authors： Hocher B,Oberthür D,Slowinski T,Querfeld U,Schaefer F,Doyon A,Tepel M,Roth HJ,Grön HJ,Reichetzeder C,Betzel C,Armbruster FP

更新日期：2013-01-01 00:00:00

abstract：:Obesity increases the risk for chronic kidney disease (CKD). By analyzing data on individuals who underwent general health screening in two consecutive years, we investigated whether changes in body mass index (BMI) or waist circumference (WC) were associated with the appearance or disappearance of the CKD components;...

journal_title：Kidney & blood pressure research

authors： Ishizaka Y,Ishizaka N,Tani M,Toda A,Toda E,Koike K,Nagai R,Yamakado M

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND/AIMS:This study aimed to investigate the potential beneficial anti-proteinuric effect of an add-on aldosterone blockade and the impact of the aldosterone escape phenomenon. METHODS:We retrospectively analyzed data of 304 patients with persistent proteinuria, who were administered spironolactone (25 mg/day) ...

journal_title：Kidney & blood pressure research

authors： Kim HY,Bae EH,Ma SK,Kim SW

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND/AIMS:Hemodialysis (HD) patients often have inadequate nutrition, especially with respect to ascorbic acid (AA). It is reported that every HD session may cause a 50%- 75% decrease in plasma AA levels. Some studies have shown that supplementation of AA can change the outcome of chronic kidney disease-mineral b...

journal_title：Kidney & blood pressure research

authors： Ke G,Huang J,Zhu Y,Yang J,Zhang Y,Chen L,Hu J,Tao S,Hu Y,Yang D,Liu S

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND/AIMS:Subclinical hypovolemia may contribute to allograft dysfunction in long-term kidney transplant (KT) patients. In order to predict responsiveness to saline hydration, indices for tubular transport were investigated. METHODS:Fifty-four clinically euvolemic long-term KT patients with recently aggravated a...

journal_title：Kidney & blood pressure research

authors： Choi JW,Park JS,Koo TY,Lee CH,Kang CM,Kim GH

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND/AIMS:To date, there is no imaging technique to assess tubular function in vivo. Blood oxygen level-dependent magnetic resonance imaging (BOLD MRI) measures tissue oxygenation based on the transverse relaxation rate (R2*). The present study investigates whether BOLD MRI can assess tubular function using a tub...

journal_title：Kidney & blood pressure research

authors： Bauer F,Wald J,Bauer FJ,Dahlkamp LM,Seibert FS,Pagonas N,Gedat E,Babel N,Zidek W,von Bodman C,Noldus J,Liermann D,Westhoff TH

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND/AIMS:The deposition of β2-microglobulin induced by reactive inflammation causing carpal tunnel syndrome (CTS) is one of the complications of dialysis-related amyloidosis in maintenance hemodialysis (MHD) patients. Air pollution levels, especially particulate matter with an aerodynamic diameter of <2.5 mm (PM...

journal_title：Kidney & blood pressure research

authors： Weng CH,Hu CC,Yen TH,Huang WH

更新日期：2017-01-01 00:00:00

abstract：INTRODUCTION:Diabetic nephropathy (DN) and hypertensive nephrosclerosis (HN) represent the most common causes of chronic kidney disease (CKD) and many patients progress to -end-stage renal disease. Patients are treated primarily through the management of cardiovas-cular risk factors and hypertension; however patients w...

journal_title：Kidney & blood pressure research

authors： Smith A,Iablokov V,Mazza M,Guarnerio S,Denti V,Ivanova M,Stella M,Piga I,Chinello C,Heijs B,van Veelen PA,Benediktsson H,Muruve DA,Magni F

更新日期：2020-01-01 00:00:00

abstract：:The high mortality rate seen in dialysis patients is related to long-standing high blood pressure and the presence of other traditional as well as non-traditional risk factors for cardiovascular disease. Hypertension is associated with increased risk for left ventricular hypertrophy, coronary artery disease, congestiv...

journal_title：Kidney & blood pressure research

authors： Hörl MP,Hörl WH

更新日期：2003-01-01 00:00:00

abstract：BACKGROUNDS/AIMS:Vitamin C is an antioxidant and acts as a cofactor for several key enzymatic catalytic reactions in animals. Amphibians produce vitamin C in their kidneys, as opposed to mammals that produce vitamin C in their liver. Gulo serves as a crucial enzyme for vitamin C synthesis in mammals, but the characteri...

journal_title：Kidney & blood pressure research

authors： Xie Y,Liu Y,Zhao Y,Wang H,Liu Y,Wang H,Li M,Zhao H,Zhou Q,Lv X

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:In uremic patients coronary surgery and the entire perioperative management is demanding. METHODS:We analyzed retrospectively data from all patients requiring chronic hemodialysis who under went coronary artery bypass grafting (CABG) between January 1 2001 and December 31 2004 at the Deutsches Herzzentrum B...

journal_title：Kidney & blood pressure research

authors： Krabatsch T,Yeter R,Hetzer R

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND/AIMS:We explored the effects of catechins (decaffeinated green tea extracts containing (-)-epicatechin, (-)-epigallocatechin, (-)-epicatechin gallate and (-)-epigallocatechin gallate) on atherosclerosis risk factors, oxidized low-density lipoprotein (oxLDL) and its primary metabolite, phosphatidylcholine hyd...

journal_title：Kidney & blood pressure research

authors： Chang HH,Chien CY,Chen KH,Huang SC,Chien CT

更新日期：2017-01-01 00:00:00