Association between changes in obesity parameters and incidence of chronic kidney disease in Japanese individuals.

abstract：BACKGROUND/AIMS:To prevent contrast induced renal dysfunction a periprocedural prophylactic hydration is applied. Due to dilution it should cause a drop in serum creatinine concentration (SCR). Surprisingly, no reduction in SCR after contrast admission is found in up to 25% of patients as early as 12-18 hours after cor...

journal_title：Kidney & blood pressure research

authors： Burchardt P,Rzezniczak J,Synowiec T,Angerer D,Palasz A,Zurawski J

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND/AIMS:The kinases SPAK (SPS1-related proline/alanine-rich kinase) and OSR1 (oxidative stress-responsive kinase 1) participate in the regulation of the NaCl cotransporter NCC and the Na+, K+, 2Cl- cotransporter NKCC2. The kinases are regulated by WNK (with-no-K[Lys]) kinases. Mutations of genes encoding WNK ki...

journal_title：Kidney & blood pressure research

authors： Elvira B,Munoz C,Borras J,Chen H,Warsi J,Ajay SS,Shumilina E,Lang F

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND/AIMS:Interleukin (IL)-18, a member of the IL-1 cytokine superfamily, is recognized as an important regulator of immune responses. The aim of our study was to investigate the IL-18 levels in serum and urine from children with idiopathic nephrotic syndrome (INS) during relapse and remission, and to evaluate th...

journal_title：Kidney & blood pressure research

authors： Kiliś-Pstrusińska K,Medyńska A,Zwolińska D,Wawro A

更新日期：2008-01-01 00:00:00

abstract：:Since reports of the first data on cytokines in renal diseases about 10 years ago, the field has seen an explosive growth over the last decade. It is now realized that cytokines can be synthesized by many different types of cells, including glomerular cells, upon adequate stimulation and exert a wide range of actions ...

journal_title：Kidney & blood pressure research

authors： Ostendorf T,Burg M,Floege J

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND/AIMS:Excessive phosphate concentrations trigger vascular calcification, an active process promoted by osteoinduction of vascular smooth muscle cells (VSMCs) with increased expression and activity of transcription factor RUNX2 (Core-binding factor α1, CBFA1), alkaline phosphatase (ALPL), TGFß1, transcription ...

journal_title：Kidney & blood pressure research

authors： Alesutan I,Musculus K,Castor T,Alzoubi K,Voelkl J,Lang F

更新日期：2015-01-01 00:00:00

abstract：AIMS:The aim of this study was to screen several novel genes associated with renal cell carcinoma (RCC), and analyze the gene functions and signal pathways which were critical to RCCs with DNA microarray. METHODS:The gene expression profile of GSE781 was downloaded from Gene Expression Omnibus database, including 9 RC...

journal_title：Kidney & blood pressure research

authors： Li W,Zhu W,Che J,Sun W,Liu M,Peng B,Zheng J

更新日期：2013-01-01 00:00:00

abstract：:Recently, Chlamydia pneumoniae is the microorganism frequently implicated in the infection-based inflammatory atherogenous hypothesis. Although in vitro experimental data and initial sero-epidemiologic, pathology-based studies and antibiotic trials supported this interesting hypothesis, later data are conflicting. Som...

journal_title：Kidney & blood pressure research

authors： Tsirpanlis G

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND/AIMS:To date, there is no imaging technique to assess tubular function in vivo. Blood oxygen level-dependent magnetic resonance imaging (BOLD MRI) measures tissue oxygenation based on the transverse relaxation rate (R2*). The present study investigates whether BOLD MRI can assess tubular function using a tub...

journal_title：Kidney & blood pressure research

authors： Bauer F,Wald J,Bauer FJ,Dahlkamp LM,Seibert FS,Pagonas N,Gedat E,Babel N,Zidek W,von Bodman C,Noldus J,Liermann D,Westhoff TH

更新日期：2017-01-01 00:00:00

abstract：:NGAL (neutrophil gelatinase-associated lipocalin) is an acute phase protein, participating in antibacterial immunity. NGAL forms a complex with metalloproteinase 9 (MMP-9), thereby increasing its activity and preventing its degradation. NGAL is freely filtered through the glomerular membrane and reabsorbed by endocyto...

journal_title：Kidney & blood pressure research

authors： Helanova K,Spinar J,Parenica J

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND/AIMS:Subclinical hypovolemia may contribute to allograft dysfunction in long-term kidney transplant (KT) patients. In order to predict responsiveness to saline hydration, indices for tubular transport were investigated. METHODS:Fifty-four clinically euvolemic long-term KT patients with recently aggravated a...

journal_title：Kidney & blood pressure research

authors： Choi JW,Park JS,Koo TY,Lee CH,Kang CM,Kim GH

更新日期：2012-01-01 00:00:00

abstract：:Dopamine (DA) is a natriuretic hormone synthesized in the kidneys by conversion of filtered 3,4-dihydroxyphenylalanine (L-Dopa), and is activated during hypervolaemia and increased dietary sodium intake. The natriuretic activity of endogenous DA is controversial, however, and the regulation of renal DA synthesis has y...

journal_title：Kidney & blood pressure research

authors： Hansell P,Källskog O,Wolgast M

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND/AIMS:Analysis of gene expression in renal tissue is considered to be a diagnostic tool predicting the clinical course of glomerulonephritis. The present study quantified the relative transcript levels of VEGF, CTGF and HIF-1α in renal tissue to establish their relationship with some clinical variables in pat...

journal_title：Kidney & blood pressure research

authors： Donderski R,Szczepanek J,Domagalski K,Tretyn A,Korenkiewicz J,Marszałek A,Szymański A,Wolski Z,Odrowąż-Sypniewska G,Manitius J

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND AND AIM:Cinacalcet effectively reduces calcium in patients with persistent hyperparathyroidism (HPT) after kidney transplantation. We aimed to assess the association of cinacalcet with a decrease in renal function based on a meta-analysis of observational studies in kidney transplant patients with persistent...

journal_title：Kidney & blood pressure research

authors： Henschkowski J,Bischoff-Ferrari HA,Wüthrich RP,Serra AL

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND/AIMS:Diabetes mellitus can exacerbate renal ischemia-reperfusion (I/R) injury (RI/RI). The aim of the present study was to evaluate the protective effect of GSK-3β inhibition (TDZD-8) on I/R-induced renal injury through the Nrf2/HO-1 pathway in a streptozocin (STZ)-induced diabetic rat model. METHODS:STZ-in...

journal_title：Kidney & blood pressure research

authors： Shen X,Hu B,Xu G,Chen F,Ma R,Zhang N,Liu J,Ma X,Zhu J,Wu Y,Shen R

更新日期：2017-01-01 00:00:00

abstract：:Angiotensin-(1-7), (Ang-(1-7)), a metabolite of Ang II and /or Ang I, was infused into the renal artery (i.r.a) of anesthetized dogs in order to demonstrate its possible direct renal action. The dose administered, 15 Ig/kg BW/min in isotonic saline (0.072 ml/kg BW/min) throughout the experiment, did not influence the ...

journal_title：Kidney & blood pressure research

authors： Heller J,Kramer HJ,Malý J,Cervenka L,Horácek V

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:The oxidative stress-responsive kinase 1 (OSR1) participates in the WNK-(with no K) kinase dependent regulation of renal salt excretion and blood pressure. Little is known, however, about the role of OSR1 in the regulation of further renal transport systems. The present study analyzed the effect of OSR1 on N...

journal_title：Kidney & blood pressure research

authors： Pathare G,Föller M,Daryadel A,Mutig K,Bogatikov E,Fajol A,Almilaji A,Michael D,Stange G,Voelkl J,Wagner CA,Bachmann S,Lang F

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND/AIMS:Either protein-to-creatinine ratio (PCR) or albumin-to-creatinine ratio (ACR) can be adopted for estimation of proteinuria in patients with chronic kidney disease (CKD). Estimated protein excretion rate (ePER) and estimated albumin excretion rate (eAER) may be superior to ACR and PCR. Reports show that ...

journal_title：Kidney & blood pressure research

authors： Hong DS,Oh IH,Park JS,Lee CH,Kang CM,Kim GH

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND/AIMS:Hemodialysis (HD) patients often have inadequate nutrition, especially with respect to ascorbic acid (AA). It is reported that every HD session may cause a 50%- 75% decrease in plasma AA levels. Some studies have shown that supplementation of AA can change the outcome of chronic kidney disease-mineral b...

journal_title：Kidney & blood pressure research

authors： Ke G,Huang J,Zhu Y,Yang J,Zhang Y,Chen L,Hu J,Tao S,Hu Y,Yang D,Liu S

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND/AIMS:IgA nephropathy is the most prevalent form of primary glomerulonephritis worldwide. Among patients with kidney disease, hypertension is one of the most important risk factors of disease progression. Considering the limited evidence regarding the appropriate blood pressure (BP) goal for patients with IgA...

journal_title：Kidney & blood pressure research

authors： Zheng Y,Wang Y,Liu S,Wu J,Duan S,Zhu H,Wu D,Cai G,Chen X

更新日期：2018-01-01 00:00:00

abstract：:Fibroblast growth factor 23 (FGF23) is released primarily from osteoblasts/osteocytes in bone. In cooperation with the transmembrane protein Klotho, FGF23 is a powerful inhibitor of 1α 25OH Vitamin D Hydroxylase (Cyp27b1) and thus of the formation of 1,25-dihydroxyvitamin D3 (1,25(OH)2D3). As 1,25(OH)2D3 up-regulates ...

journal_title：Kidney & blood pressure research

authors： Lang F,Leibrock C,Pandyra AA,Stournaras C,Wagner CA,Föller M

更新日期：2018-01-01 00:00:00

abstract：INTRODUCTION:There is still no evidence whether human peritoneal mesothelial cells (HPMC) from patients with end-stage renal failure are altered in cell viability or show a different pattern of the release of proinflammatory cytokines. Also the serum of patients with uremia may contain substances stimulating the cytoki...

journal_title：Kidney & blood pressure research

authors： Plum J,Fleisch MC,Razeghi P,Fusshöller A,Lordnejad MR,Grabensee B

更新日期：2002-01-01 00:00:00

abstract：:Renal proximal tubular Na/phosphate cotransport is the key target in the control of renal phosphate handling. Using molecular tools for the type II Na/phosphate cotransporter, it could be documented that altered brush border membrane phosphate transport reflects a state of altered brush border expression of the specif...

journal_title：Kidney & blood pressure research

authors： Murer H,Lötscher M,Kaissling B,Biber J

更新日期：1996-01-01 00:00:00

abstract：:Acute kidney injury (AKI) is a complex kidney disorder that leads to numerous complications, such as elevated nitrogenous wastes, metabolic acidosis, high potassium levels and even death. The pathogenesis of AKI is very complicated, and its causes are commonly categorized as prerenal, intrinsic or postrenal. In the pa...

journal_title：Kidney & blood pressure research

authors： Zhou P,Chen Z,Zou Y,Wan X

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Vascular accesses (especially polytetrafluoroethylene grafts) with a permanently low flow (Qa <600 ml/min) are prone to thrombosis and thus have short patency. The reason for a permanently low flow is usually medial calcinosis of the inflow artery in diabetics. We retrospectively studied the long-term patenc...

journal_title：Kidney & blood pressure research

authors： Malik J,Tuka V,Chytilova E,Mokrejsova M,Masek M,Slavikova M

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND/AIMS:Cardiorenal syndrome type 1 (CRS1) is a syndrome characterized by a rapid worsening of cardiac function leading to acute kidney injury (AKI). The aims of this study were to investigate the risk factors and the prognosis of CRS1 in elderly patients. METHODS:A total of 312 elderly patients (≥60 years old...

journal_title：Kidney & blood pressure research

authors： Hu W,He W,Liu W,Fang X,Wu Y,Yu F,Hao W

更新日期：2016-01-01 00:00:00

abstract：BACKGROUNDS/AIMS:Vitamin C is an antioxidant and acts as a cofactor for several key enzymatic catalytic reactions in animals. Amphibians produce vitamin C in their kidneys, as opposed to mammals that produce vitamin C in their liver. Gulo serves as a crucial enzyme for vitamin C synthesis in mammals, but the characteri...

journal_title：Kidney & blood pressure research

authors： Xie Y,Liu Y,Zhao Y,Wang H,Liu Y,Wang H,Li M,Zhao H,Zhou Q,Lv X

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND/AIMS:Peritoneal dialysis (PD) has gained interest over the last decade as a viable option for early start dialysis. It is still unknown if shorter break-in periods and less time for proper patient evaluation and training could influence technique survival in comparison to planned-start PD. METHODS:A prospec...

journal_title：Kidney & blood pressure research

authors： Silva BC,Adelina E,Pereira BJ,Cordeiro L,Rodrigues CE,Duarte RJ,Abensur H,Elias RM

更新日期：2018-01-01 00:00:00

abstract：:The interaction between renal nerves, endothelins acting via endothelin-A receptors and vasopressin in the regulation of renal excretory function was investigated. In conscious intact and renal denervated diabetes insipidus (DI) Brattleboro rats, as well as their controls, Long-Evans (LE) rats, an infusion of 16.4 nmo...

journal_title：Kidney & blood pressure research

authors： Girchev R,Markova P,Mikhov D,Avramova T,Nattcheff N

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Post-transplant diabetes mellitus (PTDM) is a common and serious metabolic complication. Genetic polymorphisms of angiotensin-converting enzyme (ACE) and angiotensinogen (AGT) genes have been reported to be related to diabetes mellitus and insulin sensitivity; however, the role of these genes in the developm...

journal_title：Kidney & blood pressure research

authors： Lee Sr,Moon JY,Lee SH,Ihm CG,Lee TW,Kim SK,Chung JH,Kang SW,Kim TH,Park SJ,Kim YH,Jeong KH

更新日期：2013-01-01 00:00:00

abstract：:Although primary cilia are increasingly recognized to play sensory roles in several cellular systems, their role in vascular smooth muscle cells (VSMCs) has not been defined. We examined in situ position/orientation of primary cilia and ciliary proteins in VSMCs and tested the hypothesis that primary cilia of VSMCs ex...

journal_title：Kidney & blood pressure research

authors： Lu CJ,Du H,Wu J,Jansen DA,Jordan KL,Xu N,Sieck GC,Qian Q

更新日期：2008-01-01 00:00:00