The adrenal glands as suppliers of plasma L-Dopa and sources of urinary dopamine.

abstract：:In the failing heart, the local angiotensin II concentration is increased, and the extent of cardiac angiotensin II release is related to the clinical signs of heart failure. The enzymes involved in myocardial generation of angiotensin II are the angiotensin-converting enzyme (ACE) and chymases. While myocardial angio...

journal_title：Kidney & blood pressure research

authors： Schulz R,Heusch G

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND/AIMS:Kidney function is critical for homocysteine (Hcy) clearance, and plasma Hcy levels are frequently increased in patients with renal failure. Microalbuminuria (MAU) is an important marker of early renal damage caused by hypertension. At present, there is insufficient evidence on the relationship between ...

journal_title：Kidney & blood pressure research

authors： Kuang ZM,Wang Y,Feng SJ,Jiang L,Cheng WL

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND/AIMS:Lowering dialysate temperature to increase intradialytic hemodynamic stability may interfere with the ultrafiltration-dependent intradialytic autonomic cardiovascular regulation. The present study aimed to investigate hemodynamic and autonomic responses depending on dialysate temperature and the presenc...

journal_title：Kidney & blood pressure research

authors： Zitt E,Neyer U,Meusburger E,Tiefenthaler M,Kotanko P,Mayer G,Rosenkranz AR

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Cardiac death is increased in peritoneal dialysis (PD) patients. Pulse wave velocity (PWV) is a measurement of arterial stiffness, and previous reports linked PWV to increased extracellular water (ECW). As cyclers and icodextrin are increasingly used, we wished to determine whether this association between P...

journal_title：Kidney & blood pressure research

authors： Tangvoraphonkchai K,Davenport A

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Fatty acid-bearing albumin [FA(+) albumin] exerts more deleterious effects in tubular cells than albumin alone. We investigated the effect of FA(+) albumin on the vascular cell adhesion molecule-1 (VCAM-1) expression and elucidated the underlying signaling pathways. We further examined the effect of L-carnit...

journal_title：Kidney & blood pressure research

authors： Baek JE,Yang WS,Chang JW,Kim SB,Park SK,Park JS,Lee SK

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND/AIMS:IgA nephropathy is the most prevalent form of primary glomerulonephritis worldwide. Among patients with kidney disease, hypertension is one of the most important risk factors of disease progression. Considering the limited evidence regarding the appropriate blood pressure (BP) goal for patients with IgA...

journal_title：Kidney & blood pressure research

authors： Zheng Y,Wang Y,Liu S,Wu J,Duan S,Zhu H,Wu D,Cai G,Chen X

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Treatment with angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin 2 receptor blockers (ARBs) is associated with an increased risk for acute kidney injury after cardiovascular interventions. However, for patients undergoing kidney biopsy, no data is available. METHODS:Four hundred and sixty-six ...

journal_title：Kidney & blood pressure research

authors： Friedl A,Peric S,Masghati S,Wolzt M,Hörl WH,Soleiman A,Fuhrmann V,Haider DG

更新日期：2012-01-01 00:00:00

abstract：:NGAL (neutrophil gelatinase-associated lipocalin) is an acute phase protein, participating in antibacterial immunity. NGAL forms a complex with metalloproteinase 9 (MMP-9), thereby increasing its activity and preventing its degradation. NGAL is freely filtered through the glomerular membrane and reabsorbed by endocyto...

journal_title：Kidney & blood pressure research

authors： Helanova K,Spinar J,Parenica J

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND/AIMS:Calcium sensing receptor (CaSR) is expressed, among others also in testis. Cinacalcet binds to the CaSR, increases sensitivity of CaSR to serum calcium and is used in the treatment of secondary hyperparathyroidism (sHPT) in chronic hemodialysis patients (HDP). In most of male HDP, serum testosterone con...

journal_title：Kidney & blood pressure research

authors： Kuczera P,Adamczak M,Wiecek A

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND/AIMS:Chronic kidney disease (CKD) is one of the major complications of hypertension. It is not only associated with the future burden of end-stage renal disease but also affects mortality and cardiovascular outcomes caused by hypertension. To help understand the pathogenesis and early prevention of progressi...

journal_title：Kidney & blood pressure research

authors： Dai H,Lu S,Tang X,Lu M,Chen R,Chen Z,Yang P,Liu C,Zhou H,Lu Y,Yuan H

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND/AIMS:Lipopolysaccharides (LPS) binding to Toll-like receptor 4 (TLR4) activate NADPH oxidase gp91 subunit-mediated inflammation and oxidative damage. Recognizing the high binding affinity of sialic acid (SA) with LPS, we further explored the preventive potential of SA pretreatment on LPS-evoked acute renal f...

journal_title：Kidney & blood pressure research

authors： Hsu SP,Chen CC,Chien CT

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Magnoline is an active ingredient of magnolia fargesii with anti-inflammatory and anti-platelet effects. The objective is to explore the renoprotection of magnoline in diabetic rats and its effects on P-selectin. METHODS:Thirty-six rats were randomized into 4 groups-normal control group (C), d...

journal_title：Kidney & blood pressure research

authors： Zhou Y,Wang F,Hao L,Wang N

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND/AIMS:The Janus kinase 3 JAK3 participates in the signaling of immune cells. Lack of JAK3 triggers inflammatory bowel disease, which in turn has been shown to affect intestinal activity of the epithelial Na(+) channel ENaC and thus colonic sodium absorption. At least in theory, inflammatory bowel disease in J...

journal_title：Kidney & blood pressure research

authors： Umbach AT,Luo D,Bhavsar SK,Hosseinzadeh Z,Lang F

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND/AIMS:Rapamycin inhibits cyst growth in polycystic kidney disease by targeting the mammalian target of rapamycin (mTOR). To determine if this is a class effect of the mTOR inhibitors, we examined the effect of everolimus, the analogue of rapamycin, on disease progression in the Han:SPRD rat model of polycysti...

journal_title：Kidney & blood pressure research

authors： Wu M,Wahl PR,Le Hir M,Wackerle-Men Y,Wuthrich RP,Serra AL

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND/AIMS:Chronic kidney disease (CKD) is often accompanied by hyperlipidemia, which accelerates progression of the disease. Podocyte injury can lead to dysfunction of the glomerular filtration barrier, which is associated with proteinuria, a risk marker for the progression of CKD. Our previous studies demonstrat...

journal_title：Kidney & blood pressure research

authors： Liu T,Chen XM,Sun JY,Jiang XS,Wu Y,Yang S,Huang HZ,Ruan XZ,Du XG

更新日期：2018-01-01 00:00:00

abstract：:Renal proximal tubular Na/phosphate cotransport is the key target in the control of renal phosphate handling. Using molecular tools for the type II Na/phosphate cotransporter, it could be documented that altered brush border membrane phosphate transport reflects a state of altered brush border expression of the specif...

journal_title：Kidney & blood pressure research

authors： Murer H,Lötscher M,Kaissling B,Biber J

更新日期：1996-01-01 00:00:00

abstract：:Primary cardiac hemangioma is a very rare benign vascular tumor, with valvular hemangiomas being even less frequent as valves are generally avascular structures. We present the first case of mitral valve hemangioma in a renal transplant recipient. Patient presented with progressive dyspnea. Transesophageal echocardiog...

journal_title：Kidney & blood pressure research

authors： Juric I,Hadzibegovic I,Kes P,Biocina B,Milicic D,Basic-Jukic N

更新日期：2013-01-01 00:00:00

abstract：:MicroRNAs (miRNAs) are short, single-stranded, noncoding RNAs that modulate many key biological processes by simultaneously suppressing multiple target genes. Among them, miR-26a, a conserved miRNA among vertebrates, is highly expressed in various tissues. Accumulating evidence demonstrates that miR-26a plays pivotal ...

journal_title：Kidney & blood pressure research

authors： Li X,Pan X,Fu X,Yang Y,Chen J,Lin W

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND/AIMS:This study aimed to investigate the potential beneficial anti-proteinuric effect of an add-on aldosterone blockade and the impact of the aldosterone escape phenomenon. METHODS:We retrospectively analyzed data of 304 patients with persistent proteinuria, who were administered spironolactone (25 mg/day) ...

journal_title：Kidney & blood pressure research

authors： Kim HY,Bae EH,Ma SK,Kim SW

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND/AIMS:Diabetes mellitus can exacerbate renal ischemia-reperfusion (I/R) injury (RI/RI). The aim of the present study was to evaluate the protective effect of GSK-3β inhibition (TDZD-8) on I/R-induced renal injury through the Nrf2/HO-1 pathway in a streptozocin (STZ)-induced diabetic rat model. METHODS:STZ-in...

journal_title：Kidney & blood pressure research

authors： Shen X,Hu B,Xu G,Chen F,Ma R,Zhang N,Liu J,Ma X,Zhu J,Wu Y,Shen R

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Metabolic acidosis may be diagnosed as chronic (cMA) if it persists for at least 5 days, although an exact definition has not been provided by any guidelines yet. The most common cause is CKD; numerous less-known diseases can also account for cMA. SUMMARY:In recent years, CKD-associated cMA has been propose...

journal_title：Kidney & blood pressure research

authors： Patschan D,Patschan S,Ritter O

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND/AIMS:We have reported that the long-term administration of angiotensin II receptor blockers (ARBs) induced unusual proliferative changes of renal afferent arteriolar smooth muscle cells (SMCs) in rats, associated with the overproduction of renin. In this study, we examined that a direct renin inhibitor (DRI:...

journal_title：Kidney & blood pressure research

authors： Nagai Y,Nakanishi K,Yamanaka N

更新日期：2016-01-01 00:00:00

abstract：:The German Collaborative Glomerulonephritis Therapy Study, which celebrated its 10th anniversary in 1996, has collected data on more than 1,000 patients with biopsy-proven glomerulonephritis. 929 patients could be evaluated and 500 were treated according to at least one of various protocols developed for a randomized ...

journal_title：Kidney & blood pressure research

authors： Risler T,Braun N,Bach D,Fünfstück R,Grabensee B,Grupp C,Haufe C,Heering P,Keller F,Krämer B,Müller GA,Schollmeyer P,Stein G,Zäuner I

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Neutrophil gelatinase-associated lipocalin (NGAL), a widely accepted diagnostic marker of acute renal injury (AKI) may be involved in the development of atherosclerosis. PURPOSE:To assess the prognostic significance of serum and urinary NGAL and serum cystatin C in patients with stable angina undergoing per...

journal_title：Kidney & blood pressure research

authors： Bachorzewska-Gajewska H,Tomaszuk-Kazberuk A,Jarocka I,Mlodawska E,Lopatowska P,Zalewska-Adamiec M,Dobrzycki S,Musial WJ,Malyszko J

更新日期：2013-01-01 00:00:00

abstract：INTRODUCTION:There is still no evidence whether human peritoneal mesothelial cells (HPMC) from patients with end-stage renal failure are altered in cell viability or show a different pattern of the release of proinflammatory cytokines. Also the serum of patients with uremia may contain substances stimulating the cytoki...

journal_title：Kidney & blood pressure research

authors： Plum J,Fleisch MC,Razeghi P,Fusshöller A,Lordnejad MR,Grabensee B

更新日期：2002-01-01 00:00:00

abstract：:Patients affected by end-stage renal disease (ESRD) show quite lower physical activity and exercise capacity when compared to healthy individuals. In addition, a sedentary lifestyle is favoured by lack of a specific counseling on exercise implementation in the nephrology care setting. Increasing physical activity leve...

journal_title：Kidney & blood pressure research

authors： Capitanini A,Lange S,D'Alessandro C,Salotti E,Tavolaro A,Baronti ME,Giannese D,Cupisti A

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Urine osmolality indicates the ability of the kidney to concentrate the urine and reflects the antidiuretic action of vasopressin. However, results about the association between urine osmolality and adverse renal outcomes in chronic kidney disease (CKD) are conflicting. We investigated the association betwee...

journal_title：Kidney & blood pressure research

authors： Lee MJ,Chang TI,Lee J,Kim YH,Oh KH,Lee SW,Kim SW,Park JT,Yoo TH,Kang SW,Choi KH,Ahn C,Han SH

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Diabetic nephropathy constitutes a large proportion of end-stage kidney failure in diabetic patients. However, the underlying molecular mechanisms remain unclear. METHODS:Db/db diabetic mouse models and high glucose (HG)-induced human renal mesangial cells (HRMCs) were used as research models in vivo and in...

journal_title：Kidney & blood pressure research

authors： Min XQ,Xie Y

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND/AIMS:IgA nephropathy is associated with aberrant O-glycosylation of IgA1, which is recognized by autoantibodies leading to the formation of circulating immune complexes. Some of them, after deposition into kidney mesangium, trigger glomerular injury. In patients with active disease nonresponding to angiotens...

journal_title：Kidney & blood pressure research

authors： Kosztyu P,Hill M,Jemelkova J,Czernekova L,Kafkova LR,Hruby M,Matousovic K,Vondrak K,Zadrazil J,Sterzl I,Mestecky J,Raska M

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:In uremic patients coronary surgery and the entire perioperative management is demanding. METHODS:We analyzed retrospectively data from all patients requiring chronic hemodialysis who under went coronary artery bypass grafting (CABG) between January 1 2001 and December 31 2004 at the Deutsches Herzzentrum B...

journal_title：Kidney & blood pressure research

authors： Krabatsch T,Yeter R,Hetzer R

更新日期：2005-01-01 00:00:00