Molecular mechanisms in the regulation of renal proximal tubular Na/phosphate cotransport.

abstract：BACKGROUND/AIMS:Additional validation study was warranted to confirm the clinical significance of C score, which was recently added to the Oxford classification for immunoglobulin A nephropathy (IgAN). METHODS:We performed a multicenter retrospective cohort study in four hospitals in Korea. Patients who had biopsied g...

journal_title：Kidney & blood pressure research

authors： Park S,Baek CH,Park SK,Kang HG,Hyun HS,Park E,Han SH,Ryu DR,Kim DK,Oh KH,Joo KW,Kim YS,Moon KC,Chin HJ,Lee H

更新日期：2019-01-01 00:00:00

abstract：AIM:This study investigated the impact of hypertension combined with diabetic nephropathy on rat renal alpha(1)-adrenoceptor subtype composition. METHODS:In streptozotocin-induced diabetic spontaneously hypertensive rats (SHR), diabetic nephropathy developed as reflected by increased kidney index, plasma creatinine, a...

journal_title：Kidney & blood pressure research

authors： Khan MA,Sattar MA,Abdullah NA,Abdulla MH,Salman IM,Kazi RN,Swarup KR,Rathore HA,Basri F,Hussain NM,Dewa A,Johns EJ

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND/AIMS:To gain insight into the effect of arginine vasopressin (AVP) on renal hemodynamics in hypertensive rats, we investigated the vasoconstrictive response to AVP on total renal blood flow (RBF) and total and zonal glomerular filtration rate (GFR) in young and old spontaneously hypertensive rats (SHR). A hy...

journal_title：Kidney & blood pressure research

authors： Christiansen RE,Roald AB,Gjerstad C,Tenstad O,Iversen BM

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND/AIMS:Either protein-to-creatinine ratio (PCR) or albumin-to-creatinine ratio (ACR) can be adopted for estimation of proteinuria in patients with chronic kidney disease (CKD). Estimated protein excretion rate (ePER) and estimated albumin excretion rate (eAER) may be superior to ACR and PCR. Reports show that ...

journal_title：Kidney & blood pressure research

authors： Hong DS,Oh IH,Park JS,Lee CH,Kang CM,Kim GH

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND/AIMS:Apparent treatment resistant hypertension (aTRH) is highly prevalent in patients with type 2 diabetes (T2D) and chronic kidney disease (CKD). The impact of aTRH and achievement of recommended blood pressure (BP) values on the rate of glomerular filtration rate (eGFR) loss in CKD patients is poorly known...

journal_title：Kidney & blood pressure research

authors： Viazzi F,Greco E,Ceriello A,Fioretto P,Giorda C,Guida P,Russo G,De Cosmo S,Pontremoli R,AMD-Annals Study Group.

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:The biological properties of oxidized and non-oxidized PTH are substantially different. Oxidized PTH (oxPTH) loses its PTH receptor-stimulating properties, whereas non-oxidized PTH (n-oxPTH) is a full agonist of the receptor. This was described in more than 20 well published studies in the 1970(s) and 80(s)....

journal_title：Kidney & blood pressure research

authors： Hocher B,Oberthür D,Slowinski T,Querfeld U,Schaefer F,Doyon A,Tepel M,Roth HJ,Grön HJ,Reichetzeder C,Betzel C,Armbruster FP

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Cardiovascular disease caused by atherosclerosis remains a major cause of morbidity and mortality in patients with end-stage renal disease (ESRD). We evaluated the potential association of cardiovascular risk factors including asymmetric dimethyl L-arginine (ADMA) and the soluble receptor for advanced glycat...

journal_title：Kidney & blood pressure research

authors： Pitha J,Teplan V,Kalousova M,Racek J,Stollova M,Marečková O,Lanska V

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND/AIMS:Acute kidney injury (AKI) is a serious complication of sepsis and has a high morbidity and mortality rate. Caspase-11 induces pyroptosis, a form of programmed cell death that plays a critical role in endotoxic shock, but its role in tubular epithelial cell death and whether it contributes to sepsis-asso...

journal_title：Kidney & blood pressure research

authors： Ye Z,Zhang L,Li R,Dong W,Liu S,Li Z,Liang H,Wang L,Shi W,Malik AB,Cheng KT,Liang X

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:1,25-Dihydroxyvitamin D(3) is mainly synthesized by renal proximal tubular cells. More recently, it has been shown to affect cell growth and TGF-beta(1) synthesis in glomerular and tubular renal cells in vitro, and to prevent glomerulosclerosis in vivo in subtotally nephrectomized rats. The mechanisms involv...

journal_title：Kidney & blood pressure research

authors： Weinreich T,Wüthrich RP,Booy C,Binswanger U

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Cardiovascular complications are a major cause of morbidity and mortality in chronic renal failure (CRF) patients. Chronic anemia is a complication of CRF and a cardiovascular risk factor per se. It was the aim of the present study to clarify whether uremia and anemia are additive or supra-additive with resp...

journal_title：Kidney & blood pressure research

authors： Jürgensen JS,Grimm R,Benz K,Philipp S,Eckardt KU,Amann K

更新日期：2010-01-01 00:00:00

abstract：AIM:To assess the influence on blood pressure in schoolchildren, of elevated sodium (Na(+)) and nitrate (NO(-)(3)) levels in the drinking water. METHODS:The blood pressure was recorded in three groups of age- and weight-matched schoolchildren (fourth and fifth graders) ingesting differing Na(+) and NO(-)(3) concentrat...

journal_title：Kidney & blood pressure research

authors： Pomeranz A,Korzets Z,Vanunu D,Krystal H,Wolach B

更新日期：2000-01-01 00:00:00

abstract：:Primary cardiac hemangioma is a very rare benign vascular tumor, with valvular hemangiomas being even less frequent as valves are generally avascular structures. We present the first case of mitral valve hemangioma in a renal transplant recipient. Patient presented with progressive dyspnea. Transesophageal echocardiog...

journal_title：Kidney & blood pressure research

authors： Juric I,Hadzibegovic I,Kes P,Biocina B,Milicic D,Basic-Jukic N

更新日期：2013-01-01 00:00:00

abstract：:Currently, the pathogenesis of nondipper hypertension remains largely unclear in patients without any renal or endocrine pathology. It is well known that overt hypothyroidism is strongly associated with diastolic hypertension. However, no study has addressed the pathogenic role of TSH, free T3 (FT3), and free T4 (FT4)...

journal_title：Kidney & blood pressure research

authors： Kanbay M,Turgut F,Karakurt F,Isik B,Alkan R,Akcay A,Yigitoglu R,Covic A

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND/AIMS:To prevent contrast induced renal dysfunction a periprocedural prophylactic hydration is applied. Due to dilution it should cause a drop in serum creatinine concentration (SCR). Surprisingly, no reduction in SCR after contrast admission is found in up to 25% of patients as early as 12-18 hours after cor...

journal_title：Kidney & blood pressure research

authors： Burchardt P,Rzezniczak J,Synowiec T,Angerer D,Palasz A,Zurawski J

更新日期：2016-01-01 00:00:00

abstract：:The effects on glomerular hemodynamics of angiotensin-converting enzyme (ACE) inhibition with captopril and of angiotensin II receptor blockade with EXP 3174, an active metabolite of losartan, either alone or in combination, were compared in anesthetized dogs. Administration of EXP 3174 intrarenally led to an increase...

journal_title：Kidney & blood pressure research

authors： Heller J,Kramer HJ,Horácek V

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND/AIMS:Ischemia/reperfusion (I/R) is the most common cause of acute renal injury. I/R-induced oxidative stress is involved in the development of acute renal injury, which can be reversed by supplementation with L-arginine, a precursor of nitric oxide (NO). This study was conducted to evaluate alterations in th...

journal_title：Kidney & blood pressure research

authors： Tong F,Zhou X

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND/AIMS:This study aimed to investigate the potential beneficial anti-proteinuric effect of an add-on aldosterone blockade and the impact of the aldosterone escape phenomenon. METHODS:We retrospectively analyzed data of 304 patients with persistent proteinuria, who were administered spironolactone (25 mg/day) ...

journal_title：Kidney & blood pressure research

authors： Kim HY,Bae EH,Ma SK,Kim SW

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Neutrophil gelatinase-associated lipocalin (NGAL), a widely accepted diagnostic marker of acute renal injury (AKI) may be involved in the development of atherosclerosis. PURPOSE:To assess the prognostic significance of serum and urinary NGAL and serum cystatin C in patients with stable angina undergoing per...

journal_title：Kidney & blood pressure research

authors： Bachorzewska-Gajewska H,Tomaszuk-Kazberuk A,Jarocka I,Mlodawska E,Lopatowska P,Zalewska-Adamiec M,Dobrzycki S,Musial WJ,Malyszko J

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND/AIMS:We previously showed that urine and serum Angiopoietin-2 (Ang-2) levels increased significantly with the degree of albuminuria in diabetes patients, but the reasons remain unclear. Consequently we aimed to determine whether there was an association between Ang-2, inflammatory cytokines (TNF-α and IL-18)...

journal_title：Kidney & blood pressure research

authors： He FF,Li HQ,Huang QX,Wang QY,Jiang HJ,Chen S,Su H,Zhang C,Wang YM

更新日期：2015-01-01 00:00:00

abstract：AIM:The aim of the present study was to evaluate the influence of cycle exercise during hemodialysis (HD) on patients' physical proficiency, muscle strength, quality of life and selected laboratory parameters. PATIENTS AND METHODS:In a group of 29 (15 female, 14 male) HD patients (age 64.2 ± 13.1 years), 3 months of c...

journal_title：Kidney & blood pressure research

authors： Gołębiowski T,Kusztal M,Weyde W,Dziubek W,Woźniewski M,Madziarska K,Krajewska M,Letachowicz K,Strempska B,Klinger M

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND/AIMS:Hypertensive patients present with increased oxidative stress and frequently receive angiotensin II (ANGII) receptor type I blockers (ARB) for blood pressure (BP) reduction. Recent studies revealed an important role of ANGII in maintaining vascular oxidative homeostasis, including sustaining normal sodi...

journal_title：Kidney & blood pressure research

authors： Mihalj M,Tadzic R,Vcev A,Rucevic S,Drenjancevic I

更新日期：2016-01-01 00:00:00

abstract：INTRODUCTION:Diabetic nephropathy (DN) is a serious complication of diabetes mellitus and is considered to be a sterile inflammatory disease. Increasing evidence suggest that pyroptosis and subsequent inflammatory response play a key role in the pathogenesis of DN. However, the underlying cellular and molecular mechani...

journal_title：Kidney & blood pressure research

authors： Zhan JF,Huang HW,Huang C,Hu LL,Xu WW

更新日期：2020-01-01 00:00:00

abstract：:The German Collaborative Glomerulonephritis Therapy Study, which celebrated its 10th anniversary in 1996, has collected data on more than 1,000 patients with biopsy-proven glomerulonephritis. 929 patients could be evaluated and 500 were treated according to at least one of various protocols developed for a randomized ...

journal_title：Kidney & blood pressure research

authors： Risler T,Braun N,Bach D,Fünfstück R,Grabensee B,Grupp C,Haufe C,Heering P,Keller F,Krämer B,Müller GA,Schollmeyer P,Stein G,Zäuner I

更新日期：1996-01-01 00:00:00

abstract：AIMS:To investigate whether the regulation of aquaporin (AQP) channels is altered by inhibition of type 2 11beta-hydroxysteroid dehydrogenase (11betaHSD2). METHODS:Male Sprague-Dawley rats were treated with glycyrrhizic acid (GA, 2 g/l drinking water) for 7 days. The expression of AQP2 and AQP3 was determined in the k...

journal_title：Kidney & blood pressure research

authors： Ma SK,Nam KI,Kim SW,Bae EH,Choi KC,Lee J

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND/AIMS:The role of endothelin (ET) in cardiovascular remodeling was investigated by treating uninephrectomized spontaneously hypertensive rats of the stroke-prone strain (UNX-SHRsp) on normal- or high (3%)-salt diet with the selective ET(A) receptor blocker LU 135252. METHODS:SHRsp on normal or high salt were...

journal_title：Kidney & blood pressure research

authors： Orth SR,Schiele G,Banas B,Ritz E,Amann K

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND/AIMS:Chronic kidney disease (CKD) is one of the major complications of hypertension. It is not only associated with the future burden of end-stage renal disease but also affects mortality and cardiovascular outcomes caused by hypertension. To help understand the pathogenesis and early prevention of progressi...

journal_title：Kidney & blood pressure research

authors： Dai H,Lu S,Tang X,Lu M,Chen R,Chen Z,Yang P,Liu C,Zhou H,Lu Y,Yuan H

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVES:This prospective, randomized study was to investigate the role of nicorandil in the prevention of contrast-induced nephropathy (CIN) in patients with chronic renal dysfunction undergoing an elective coronary procedure. METHODS:A total of 252 eligible patients were enrolled in this study and allocated into t...

journal_title：Kidney & blood pressure research

authors： Fan Z,Li Y,Ji H,Jian X

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND/AIM:Serum gamma-glutamyltransferase (GGT), a biomarker of oxidative stress, is associated with an increased risk of diabetes and hypertension. However, it is not known whether higher serum GGT is independently associated with chronic kidney disease (CKD). Therefore, we examined the association between serum ...

journal_title：Kidney & blood pressure research

authors： Teppala S,Shankar A,Li J,Wong TY,Ducatman A

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND/AIMS:To determine the effect of arterial blood pressure (BP) reduction on endocan and soluble cell adhesion molecules' (sCAM) plasma concentration and expression of their ligands on circulatory leukocyte subpopulations. METHODS:24 hypertensive subjects of both sexes (age: 53±8 yrs) were treated with Ca-chan...

journal_title：Kidney & blood pressure research

authors： Tadzic R,Mihalj M,Vcev A,Ennen J,Tadzic A,Drenjancevic I

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND/AIMS:The metabolic syndrome (MetS), as assessed using dichotomous criteria, is associated with increased risk of future chronic kidney disease (CKD), though this relationship is unclear among African Americans, who have lower risk for MetS but higher risk for CKD. METHODS:We performed logistic regression us...

journal_title：Kidney & blood pressure research

authors： DeBoer MD,Filipp SL,Musani SK,Sims M,Okusa MD,Gurka M

更新日期：2018-01-01 00:00:00