Phosphate Homeostasis, Inflammation and the Regulation of FGF-23.

abstract：BACKGROUND:Urine osmolality indicates the ability of the kidney to concentrate the urine and reflects the antidiuretic action of vasopressin. However, results about the association between urine osmolality and adverse renal outcomes in chronic kidney disease (CKD) are conflicting. We investigated the association betwee...

journal_title：Kidney & blood pressure research

authors： Lee MJ,Chang TI,Lee J,Kim YH,Oh KH,Lee SW,Kim SW,Park JT,Yoo TH,Kang SW,Choi KH,Ahn C,Han SH

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND/AIMS:The Janus kinase 3 JAK3 participates in the signaling of immune cells. Lack of JAK3 triggers inflammatory bowel disease, which in turn has been shown to affect intestinal activity of the epithelial Na(+) channel ENaC and thus colonic sodium absorption. At least in theory, inflammatory bowel disease in J...

journal_title：Kidney & blood pressure research

authors： Umbach AT,Luo D,Bhavsar SK,Hosseinzadeh Z,Lang F

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND/AIMS:The kidney plays a critical role in the control of blood pressure and its elevation in salt-induced hypertension. Mitochondrial dysfunction, especially in energy metabolism, has been associated with hypertension. Here, we aimed to investigate mitochondrial function and metabolic features in renal mitoch...

journal_title：Kidney & blood pressure research

authors： Wang Z,Sun Q,Sun N,Liang M,Tian Z

更新日期：2017-01-01 00:00:00

abstract：:In the present study, the effects of hexachlorobenzene (HCB) on lipid peroxidation and heme metabolism in the different constitutive suborgans of the kidney were determined. For this purpose, conjugated diene and malondialdehyde levels, as lipid peroxidation parameters, and porphyrin accumulation, uroporphyrinogen dec...

journal_title：Kidney & blood pressure research

authors： Fernández-Tomé MC,Billi de Catabbi SC,Aldonatti C,San Martin de Viale LC,Sterin-Speziale NB

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND/AIMS:Either protein-to-creatinine ratio (PCR) or albumin-to-creatinine ratio (ACR) can be adopted for estimation of proteinuria in patients with chronic kidney disease (CKD). Estimated protein excretion rate (ePER) and estimated albumin excretion rate (eAER) may be superior to ACR and PCR. Reports show that ...

journal_title：Kidney & blood pressure research

authors： Hong DS,Oh IH,Park JS,Lee CH,Kang CM,Kim GH

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND/AIMS:Analysis of gene expression in renal tissue is considered to be a diagnostic tool predicting the clinical course of glomerulonephritis. The present study quantified the relative transcript levels of VEGF, CTGF and HIF-1α in renal tissue to establish their relationship with some clinical variables in pat...

journal_title：Kidney & blood pressure research

authors： Donderski R,Szczepanek J,Domagalski K,Tretyn A,Korenkiewicz J,Marszałek A,Szymański A,Wolski Z,Odrowąż-Sypniewska G,Manitius J

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:The oxidative stress-responsive kinase 1 (OSR1) participates in the WNK-(with no K) kinase dependent regulation of renal salt excretion and blood pressure. Little is known, however, about the role of OSR1 in the regulation of further renal transport systems. The present study analyzed the effect of OSR1 on N...

journal_title：Kidney & blood pressure research

authors： Pathare G,Föller M,Daryadel A,Mutig K,Bogatikov E,Fajol A,Almilaji A,Michael D,Stange G,Voelkl J,Wagner CA,Bachmann S,Lang F

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Cardiovascular disease caused by atherosclerosis remains a major cause of morbidity and mortality in patients with end-stage renal disease (ESRD). We evaluated the potential association of cardiovascular risk factors including asymmetric dimethyl L-arginine (ADMA) and the soluble receptor for advanced glycat...

journal_title：Kidney & blood pressure research

authors： Pitha J,Teplan V,Kalousova M,Racek J,Stollova M,Marečková O,Lanska V

更新日期：2010-01-01 00:00:00

abstract：INTRODUCTION:There is still no evidence whether human peritoneal mesothelial cells (HPMC) from patients with end-stage renal failure are altered in cell viability or show a different pattern of the release of proinflammatory cytokines. Also the serum of patients with uremia may contain substances stimulating the cytoki...

journal_title：Kidney & blood pressure research

authors： Plum J,Fleisch MC,Razeghi P,Fusshöller A,Lordnejad MR,Grabensee B

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Hypertension in the elderly is commonly characterized by an elevation of pulse pressure. With regard to advanced arteriosclerosis and limited physical fitness, doubt was casted whether elderly patients still achieve relevant cardiovascular benefits by physical exercise. The present work examines the impact o...

journal_title：Kidney & blood pressure research

authors： Westhoff TH,Franke N,Schmidt S,Vallbracht-Israng K,Meissner R,Yildirim H,Schlattmann P,Zidek W,Dimeo F,van der Giet M

更新日期：2007-01-01 00:00:00

abstract：:The value of neutrophil-gelatinase-associated lipocalin (NGAL) was highlighted as a novel biomarker for the detection of acute renal failure. We tested the hypothesis whether NGAL could represent an early biomarker of contrast-induced nephropathy (CIN) in 100 patients with normal serum creatinine values undergoing per...

journal_title：Kidney & blood pressure research

authors： Bachorzewska-Gajewska H,Malyszko J,Sitniewska E,Malyszko JS,Pawlak K,Mysliwiec M,Lawnicki S,Szmitkowski M,Dobrzycki S

更新日期：2007-01-01 00:00:00

abstract：BACKGROUNDS:ANCA-associated vasculitis (AAV) frequently present with a chronic relapsing course. Relapse leads to an increased need for therapeutic agents and consequent toxicity. SUMMARY:When referring to the available options for the management of AAV, the efficacy of glucocorticoids (GCs) is unquestionable. However...

journal_title：Kidney & blood pressure research

authors： Fenoglio R,Roccatello D,Sciascia S

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND/AIMS:Chronic renal allograft dysfunction (CRAD) is a leading cause of long-term renal allograft loss. Oxidative stress may account for the nonspecific interstitial fibrosis and tubular atrophy that occur in CRAD. An antioxidant intervention via Nrf2 signaling pathway activation might be a promising therapy f...

journal_title：Kidney & blood pressure research

authors： Lv D,Zhou Q,Xia Y,You X,Zhao Z,Li Y,Zou H

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Cardiac death is increased in peritoneal dialysis (PD) patients. Pulse wave velocity (PWV) is a measurement of arterial stiffness, and previous reports linked PWV to increased extracellular water (ECW). As cyclers and icodextrin are increasingly used, we wished to determine whether this association between P...

journal_title：Kidney & blood pressure research

authors： Tangvoraphonkchai K,Davenport A

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND/AIMS:To date, there is no imaging technique to assess tubular function in vivo. Blood oxygen level-dependent magnetic resonance imaging (BOLD MRI) measures tissue oxygenation based on the transverse relaxation rate (R2*). The present study investigates whether BOLD MRI can assess tubular function using a tub...

journal_title：Kidney & blood pressure research

authors： Bauer F,Wald J,Bauer FJ,Dahlkamp LM,Seibert FS,Pagonas N,Gedat E,Babel N,Zidek W,von Bodman C,Noldus J,Liermann D,Westhoff TH

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Treating non-diabetic proteinuric patients with advanced renal disease with an angiotensin-converting enzyme (ACE) inhibitor is still subject to discussion. This study aims to determine the cost-effectiveness of ACE inhibitor therapy in this patient population in the Netherlands. METHODS:We compared two str...

journal_title：Kidney & blood pressure research

authors： Adarkwah CC,Gandjour A,Akkerman M,Evers S

更新日期：2013-01-01 00:00:00

abstract：:A 70-year-old female patient with advanced Shy-Drager syndrome exhibited severe orthostatic hypotension, low serum catecholamine levels, and autonomic dysfunction. She was bedridden despite oral medication with fludrocortisone, etilefrin, dihydroergotamine, L-dopa, yohimbine, and amezinium methyl sulfate. Only intrave...

journal_title：Kidney & blood pressure research

authors： Kribben A,Bremer C,Fritschka E,Koeppen S,Ahrens O,Philipp T

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND/AIMS:We previously showed that urine and serum Angiopoietin-2 (Ang-2) levels increased significantly with the degree of albuminuria in diabetes patients, but the reasons remain unclear. Consequently we aimed to determine whether there was an association between Ang-2, inflammatory cytokines (TNF-α and IL-18)...

journal_title：Kidney & blood pressure research

authors： He FF,Li HQ,Huang QX,Wang QY,Jiang HJ,Chen S,Su H,Zhang C,Wang YM

更新日期：2015-01-01 00:00:00

abstract：AIM:The aim of the present study was to evaluate the influence of cycle exercise during hemodialysis (HD) on patients' physical proficiency, muscle strength, quality of life and selected laboratory parameters. PATIENTS AND METHODS:In a group of 29 (15 female, 14 male) HD patients (age 64.2 ± 13.1 years), 3 months of c...

journal_title：Kidney & blood pressure research

authors： Gołębiowski T,Kusztal M,Weyde W,Dziubek W,Woźniewski M,Madziarska K,Krajewska M,Letachowicz K,Strempska B,Klinger M

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Mesenchymal stem cells (MSC) improve renal function and renovascular hypertension in the 2-kidney 1-clip model (2K-1C). While MSC play an immunomodulatory role, induce neoangiogenesis, and reduce fibrosis, they do not correct sodium loss by the contra-lateral kidney. OBJECTIVES:We investigated the tubular f...

journal_title：Kidney & blood pressure research

authors： Varela VA,Oliveira-Sales EB,Maquigussa E,Borges FT,Gattai PP,Novaes ADS,Shimoura CG,Campos RR,Boim MA

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND/AIMS:The role of endothelin (ET) in cardiovascular remodeling was investigated by treating uninephrectomized spontaneously hypertensive rats of the stroke-prone strain (UNX-SHRsp) on normal- or high (3%)-salt diet with the selective ET(A) receptor blocker LU 135252. METHODS:SHRsp on normal or high salt were...

journal_title：Kidney & blood pressure research

authors： Orth SR,Schiele G,Banas B,Ritz E,Amann K

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND/AIM:Calcifications of large arteries are frequent in chronic kidney disease (CKD) and may contribute to the high cardiovascular risk in this population. The aim of this study was to examine whether abdominal aortic calcification volume (AACV) was a predictor of the rate of decline in glomerular filtration ra...

journal_title：Kidney & blood pressure research

authors： Jansson H,Saeed A,Svensson MK,Finnved K,Hellström M,Guron G

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Fatty acid-bearing albumin [FA(+) albumin] exerts more deleterious effects in tubular cells than albumin alone. We investigated the effect of FA(+) albumin on the vascular cell adhesion molecule-1 (VCAM-1) expression and elucidated the underlying signaling pathways. We further examined the effect of L-carnit...

journal_title：Kidney & blood pressure research

authors： Baek JE,Yang WS,Chang JW,Kim SB,Park SK,Park JS,Lee SK

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND/AIMS:Ischemia/reperfusion (I/R) is the most common cause of acute renal injury. I/R-induced oxidative stress is involved in the development of acute renal injury, which can be reversed by supplementation with L-arginine, a precursor of nitric oxide (NO). This study was conducted to evaluate alterations in th...

journal_title：Kidney & blood pressure research

authors： Tong F,Zhou X

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Diabetic nephropathy constitutes a large proportion of end-stage kidney failure in diabetic patients. However, the underlying molecular mechanisms remain unclear. METHODS:Db/db diabetic mouse models and high glucose (HG)-induced human renal mesangial cells (HRMCs) were used as research models in vivo and in...

journal_title：Kidney & blood pressure research

authors： Min XQ,Xie Y

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND/AIMS:Renalase (gene name RNLS), a recently discovered enzyme with monoamine oxidase activity, is implicated in the degradation of catecholamines. Recent studies indicate that common variations in the gene with RNLS are associated with hypertension. The aim of this study was to examine the association between...

journal_title：Kidney & blood pressure research

authors： Wang Y,Chu C,Ren J,Mu JJ,Wang D,Liu FQ,Ren KY,Guo TS,Yuan ZY

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The antiproteinuric effect of angiotensin-converting enzyme (ACE) inhibitors appears to vary depending on the ACE insertion (I)/deletion (D) genotype in non-diabetic nephropathy. This interaction may be overcome by using an angiotensin II receptor blocker. We evaluated the short-term antiproteinuric effect o...

journal_title：Kidney & blood pressure research

authors： Park HC,Choi HY,Kim BS,Kang SW,Choi KH,Ha SK,Lee HY,Han DS

更新日期：2006-01-01 00:00:00

abstract：INTRODUCTION:Renal dysfunction is a frequent complication in patients suffering from β-thalassemia major (β-TM). The aim of this study was to analyze the renal function and urine metabolomic profile of β-TM patients undergoing transfusions and deferasirox (DFX) therapy, in order to better characterize and shed light on...

journal_title：Kidney & blood pressure research

authors： Capolongo G,Zacchia M,Beneduci A,Costantini S,Cinque P,Spasiano A,De Luca G,Di Pietro ME,Ricchi P,Trepiccione F,Capasso G,Filosa A

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND/AIMS:We explored the effects of catechins (decaffeinated green tea extracts containing (-)-epicatechin, (-)-epigallocatechin, (-)-epicatechin gallate and (-)-epigallocatechin gallate) on atherosclerosis risk factors, oxidized low-density lipoprotein (oxLDL) and its primary metabolite, phosphatidylcholine hyd...

journal_title：Kidney & blood pressure research

authors： Chang HH,Chien CY,Chen KH,Huang SC,Chien CT

更新日期：2017-01-01 00:00:00

abstract：:Dopamine (DA) is a natriuretic hormone synthesized in the kidneys by conversion of filtered 3,4-dihydroxyphenylalanine (L-Dopa), and is activated during hypervolaemia and increased dietary sodium intake. The natriuretic activity of endogenous DA is controversial, however, and the regulation of renal DA synthesis has y...

journal_title：Kidney & blood pressure research

authors： Hansell P,Källskog O,Wolgast M

更新日期：1996-01-01 00:00:00