Constipation in children: novel insight into epidemiology, pathophysiology and management.

abstract：Background/Aims:Nausea, an unpleasant symptom of diabetic gastroparesis (DMGP), has been reported to be alleviated by needleless transcutaneous electrical acupuncture (TEA). Our study was designed to utilize electroencephalography (EEG) and electrogastrography (EGG) recordings to investigate the central and peripheral ...

journal_title：Journal of neurogastroenterology and motility

authors： Sarosiek I,Song G,Sun Y,Sandoval H,Sands S,Chen J,McCallum RW

更新日期：2017-04-30 00:00:00

abstract：BACKGROUND/AIMS:The marketing of newer agents for treatment of constipation and irritable bowel syndrome with constipation (IBS-C) emphasize improvements in abdominal pain. However, it is not clear whether this observation reflects a unique visceral analgesic effect of these agents or is a general feature of effective ...

journal_title：Journal of neurogastroenterology and motility

authors： Bielefeldt K,Levinthal DJ,Nusrat S

更新日期：2016-01-31 00:00:00

abstract：Background/Aims:Integrated relaxation pressure (IRP) is defined as the average minimum esophagogastric junction (EGJ) pressure for 4 seconds of relaxation (contiguous or noncontiguous) within 10 seconds of swallowing. The durability of IRP values during successive swallows in the supine position remains to be elucidate...

journal_title：Journal of neurogastroenterology and motility

authors： Elangovan A,Shibli F,Fass R

更新日期：2021-01-28 00:00:00

abstract：BACKGROUND/AIMS:Rome criteria classifying functional gastrointestinal disorder (FGID) were updated. The aims of this study were to assess the spectra of FGID and to evaluate the applicability of Rome III criteria in Korea. METHODS:New patients who visited 2 primary clinics and 2 tertiary care hospitals were consecutiv...

journal_title：Journal of neurogastroenterology and motility

authors： Park JM,Choi MG,Cho YK,Lee IS,Kim JI,Kim SW,Chung IS

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND/AIMS:Approximately one-third of non-erosive reflux disease (NERD) patients are refractory to proton pump inhibitors (PPI) and face a therapeutic challenge. Therefore, it is important to differentiate between pathological and non-pathological reflux utilizing multichannel intraluminal impedance-pH (MII-pH) to...

journal_title：Journal of neurogastroenterology and motility

authors： Khan MQ,Alaraj A,Alsohaibani F,Al-Kahtani K,Jbarah S,Al-Ashgar H

更新日期：2014-10-30 00:00:00

abstract：Background/Aims:The prevalence of eosinophilic esophagitis (EoE) is reportedly increasing in Western countries. However, its prevalence in Korea remains unknown. We investigated the diagnostic trends and clinical characteristics of EoE in Korea. Methods:Using an endoscopic database maintained at a tertiary care center...

journal_title：Journal of neurogastroenterology and motility

authors： Kim GH,Jung KW,Jung HY,Choi KD,Lee J,Park YS,Kim SW,Lee JH,Kim DH,Ahn JY,Song HJ,Lee GH,Kim JH

更新日期：2018-04-30 00:00:00

abstract：Background/Aims:Lipopolysaccharide (LPS) is the key factor inducing mucosal and systemic inflammation in various intestinal and parenteral diseases, which could initially disrupt the epithelial barrier function. EphrinA1/ephA2 is speculated to increase the epithelial permeability for its "repulsive interaction" between...

journal_title：Journal of neurogastroenterology and motility

authors： Chen Y,Zhang L,Zhang Y,Bai T,Song J,Qian W,Hou X

更新日期：2020-07-30 00:00:00

abstract：BACKGROUND/AIMS:Rats with a spontaneous null mutation in endothelin receptor type B or Ednrb (sl/sl; spotting lethal) lack enteric neurons in the distal bowel and usually die within the first week after birth. This early postnatal lethality limits their use for examining the potential of cell therapy to treat Hirschspr...

journal_title：Journal of neurogastroenterology and motility

authors： Stamp LA,Obermayr F,Pontell L,Young HM,Xie D,Croaker DH,Song ZM,Furness JB

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND/AIMS:Researches on the potential risk factors for the development of erosive esophagitis have been conducted extensively, however, the results are conflicting. The aim of this multicenter study was to identify the prevalence rate and risk factors of erosive esophagitis and their interactions with residency s...

journal_title：Journal of neurogastroenterology and motility

authors： Seo GS,Jeon BJ,Chung JS,Joo YE,Kim GH,Baik GH,Kim DY,Shin JE,Kim HU,Park HK,Kim N

更新日期：2013-01-01 00:00:00

abstract：Background/Aims:Probiotics are expected to modify the composition of gut microbiota. We aimed to investigate the changes in the composition and diversity of gut microbiota by the administration of probiotics in healthy individuals. Methods:Twelve healthy volunteers with age range of 30-42 years provided baseline fecal...

journal_title：Journal of neurogastroenterology and motility

authors： Noh CK,Kim BS,Hong G,Cheong JY,Lee KJ

更新日期：2018-07-30 00:00:00

abstract：:That gastrointestinal motility can influence the gut microbiota has been known for decades and the clinical consequences of impaired motility, in terms of the bacterial population of the small intestine, amply illustrated by the syndrome of small intestinal bacterial overgrowth which so commonly accompanies diffuse in...

journal_title：Journal of neurogastroenterology and motility

authors： Quigley EM

更新日期：2011-04-01 00:00:00

abstract：Background/Aims:Interstitial cells play important roles in gastrointestinal (GI) neuro-smooth muscle transmission. The underlying mechanisms of colonic dysmotility have not been well illustrated. We established a partial colon obstruction (PCO) mouse model to investigate the changes of interstitial cells and the correl...

journal_title：Journal of neurogastroenterology and motility

authors： Wang Q,Zang J,Huang X,Lu H,Xu W,Chen J

更新日期：2019-10-30 00:00:00

abstract：:In predisposed individuals with long standing gastroesophageal reflux disease (GERD), esophageal squamous mucosa can transform into columnar mucosa with intestinal metaplasia, commonly called Barrett's esophagus (BE). Barrett's mucosa can develop dysplasia, which can be a precursor for esophageal adenocarcinoma (EAC)....

journal_title：Journal of neurogastroenterology and motility

authors： Patel A,Gyawali CP

更新日期：2019-04-30 00:00:00

abstract：BACKGROUND/AIMS:While it is well established that acupuncture relieves somatic pain, its therapeutic effect on visceral pain such as irritable bowel syndrome (IBS) is unclear. We evaluated the effect of acupuncture in treating visceral hyperalgesia in an animal model. METHODS:Sprague-Dawley rats (n = 8 per group) with...

journal_title：Journal of neurogastroenterology and motility

authors： Wu JC,Ziea ET,Lao L,Lam EF,Chan CS,Liang AY,Chu SL,Yew DT,Berman BM,Sung JJ

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND/AIMS:In isolated guinea-pig colon, we investigated regional differences in peristalsis evoked by intrinsic electrical nerve stimulation. METHODS:Four colonic segments from mid and distal colon of Hartley guinea pigs, were mounted horizontally in an organ bath. Measurement of pellet propulsion time, intralum...

journal_title：Journal of neurogastroenterology and motility

authors： Kwak JM,Babygirija R,Gribovskaja-Rupp I,Takahashi T,Yamato S,Ludwig K

更新日期：2013-04-01 00:00:00

abstract：:Live imaging has become an essential tool to investigate the coordinated activity and output of cellular networks. Within the last decade, 2 Nobel prizes have been awarded to recognize innovations in the field of imaging: one for the discovery, use, and optimization of the green fluorescent protein (2008) and the seco...

journal_title：Journal of neurogastroenterology and motility

authors： Boesmans W,Hao MM,Vanden Berghe P

更新日期：2015-07-30 00:00:00

abstract：Background/Aims:Current evidence suggests the presence of motility or functional abnormalities in one area of the gastrointestinal tract increases the likelihood of abnormalities in others. However, the relationship of gastroparesis to chronic constipation (slow transit constipation and dyssynergic defecation) has been...

journal_title：Journal of neurogastroenterology and motility

authors： Zikos TA,Kamal AN,Neshatian L,Triadafilopoulos G,Clarke JO,Nandwani M,Nguyen LA

更新日期：2019-04-30 00:00:00

abstract：:Patients with dyspepsia/functional dyspepsia (FD) show frequent overlapping of other gastrointestinal (GI) diseases, such as irri-table bowel syndrome, and non-GI diseases, in addition to internal subgroup overlapping. These overlap patients have more frequent or more severe symptoms, poorer health-related quality of ...

journal_title：Journal of neurogastroenterology and motility

authors： Fujiwara Y,Arakawa T

更新日期：2014-10-30 00:00:00

abstract：Background/Aims:Functional dyspepsia (FD) is characterized as chronic recurrent upper gastrointestinal symptoms in the absence of any organic disorder. We hypothesized that duodenal low-grade inflammation activates superficial afferent nerve sprouting, thereby contributing to hypersensitivity in patients with FD. Meth...

journal_title：Journal of neurogastroenterology and motility

authors： Lee MJ,Jung HK,Lee KE,Mun YC,Park S

更新日期：2019-04-30 00:00:00

abstract：BACKGROUND/AIMS:Solifenacin, a muscarinic type 3 receptor antagonist, is used to treat overactive bladder in adults. The aim of this study is to examine the efficacy of solifenacin on the symptomatic relief of diarrhea predominant irritable bowel syndrome (IBS-D). METHODS:A total of 20 patients with IBS-D were enrolle...

journal_title：Journal of neurogastroenterology and motility

authors： Fukushima Y,Suzuki H,Matsuzaki J,Kiyosue A,Hibi T

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND/AIMS:Interstitial cells of Cajal (ICC) play important functions in motor activity of the gastrointestinal tract. The role of ICC as pace-makers is well established, however their participation in neurotransmission is controversial. Studies using mutant animals that lack ICC have yielded variable conclusions ...

journal_title：Journal of neurogastroenterology and motility

authors： Sanders KM,Salter AK,Hennig GW,Koh SD,Perrino BA,Ward SM,Baker SA

更新日期：2014-04-30 00:00:00

abstract：BACKGROUND/AIMS:Gastrointestinal symptoms and hypothalamus-pituitary-adrenal (HPA) axis dysfunction are frequently observed in patients with major depression. The primary aim of the study was to investigate the relationship between HPA-axis function and self-perceived functional gastrointestinal symptoms in major depre...

journal_title：Journal of neurogastroenterology and motility

authors： Karling P,Wikgren M,Adolfsson R,Norrback KF

更新日期：2016-04-30 00:00:00

abstract：BACKGROUND/AIMS:Functional gastrointestinal disorders (FGIDs), diagnosed by symptom-based criteria due to lack of biomarkers, need translatedvalidated questionnaires in different languages. As Bengali, the mother tongue of Bangladesh and eastern India, is the seventh most spoken language in the world, we translated and...

journal_title：Journal of neurogastroenterology and motility

authors： Rahman MM,Ghoshal UC,Rowshon AH,Ahmed F,Kibria MG,Hasan M,Gwee KA,Whitehead WE

更新日期：2016-04-30 00:00:00

abstract：Background/Aims:Irritable bowel syndrome (IBS) is a common disease characterized by intestinal dysmotility, the mechanism of which remains elusive. We aim to determine whether the high-affinity choline transporter 1 (CHT1), a determinant of cholinergic signaling capacity, modulates intestinal motility associated with s...

journal_title：Journal of neurogastroenterology and motility

authors： Lin MJ,Yu BP

更新日期：2018-10-01 00:00:00

abstract：:Visceral pain is the most common form of pain caused by varied diseases and a major reason for patients to seek medical consultation. It also leads to a significant economic burden due to workdays lost and reduced productivity. Further, long-term use of non-specific medications is also associated with side effects aff...

journal_title：Journal of neurogastroenterology and motility

authors： Kannampalli P,Sengupta JN

更新日期：2015-03-30 00:00:00

abstract：:Gastroesophageal reflux disease (GERD) is a very common disease, and the prevalence in the general population has recently increased. GERD is a chronic relapsing disease associated with motility disorders of the upper gastrointestinal tract. Several factors are implicated in GERD, including hypotensive lower esophagea...

journal_title：Journal of neurogastroenterology and motility

authors： Lin S,Li H,Fang X

更新日期：2019-10-30 00:00:00

abstract：Background/Aims:Since the use of dexlansoprazole in Asian subjects with gastroesophageal reflux disease (GERD) has not been adequately characterized, this study was conducted to evaluate the efficacy and safety of dexlansoprazole modified-release in Asian subjects with non-erosive reflux disease (NERD) and erosive esop...

journal_title：Journal of neurogastroenterology and motility

authors： Wu JCY,Sheu BS,Wu MS,Lee YC,Choi MG

更新日期：2020-01-30 00:00:00

abstract：:Cyclic vomiting syndrome (CVS) is a disorder characterized by recurrent episodes of incapacitating nausea and vomiting interspersed with symptom free periods. Common triggers of cyclic vomiting include noxious stress, excitement, fatigue and menstrual period. Here, we report a case of cyclic vomiting syndrome in adult...

journal_title：Journal of neurogastroenterology and motility

authors： Shin YK,Kwon JG,Kim KY,Park JB,Han SJ,Cheon JW,Kim EY,Kim HG,Lee TS,Park KS,Won KS

更新日期：2010-01-01 00:00:00

abstract：:This article highlights the role of prucalopride in the management of chronic constipation based upon the principles of meta-analysis using data reported in the published randomized, controlled trials. Sixteen randomized, controlled trials on 3943 patients reported the effectiveness of prucalopride in patients with ch...

journal_title：Journal of neurogastroenterology and motility

authors： Sajid MS,Hebbar M,Baig MK,Li A,Philipose Z

更新日期：2016-07-30 00:00:00

abstract：BACKGROUND/AIMS:Despite numerous studies on the relation of genetic polymorphisms with irritable bowel syndrome (IBS), the results still remain inconclusive. The aim of this study was to assess the possible association between SLC6A4 serotonin transporter gene linked polymorphic region (5-HTTLPR), ADRA2A -1291C>G, GNB3...

journal_title：Journal of neurogastroenterology and motility

authors： Choi YJ,Hwang SW,Kim N,Park JH,Oh JC,Lee DH

更新日期：2014-07-31 00:00:00