A case of cyclic vomiting syndrome responding to gonadotropin-releasing hormone analogue.

Abstract:

:Cyclic vomiting syndrome (CVS) is a disorder characterized by recurrent episodes of incapacitating nausea and vomiting interspersed with symptom free periods. Common triggers of cyclic vomiting include noxious stress, excitement, fatigue and menstrual period. Here, we report a case of cyclic vomiting syndrome in adult patient characterized by stereotypical vomiting attack, occurring in every menstruation period. Recurrent vomiting episodes began 6 years ago and we treated this patient with subcutaneous injection of goserelin, a gonadotropin-releasing hormone analogue (GnRHa) and oral estrogen. After 4 months of therapy, she was symptom free for the following 5 years, even with the resumed normal menstruation. Recurrence of vomiting attack with same pattern occurred 1 month before readmission. Treatment with intravenous lorazepam aborted vomiting, but could not prevent recurrences of vomiting and epigastric pain. We treated the patient with GnRHa and oral estradiol again which effectively prevented recurrence of the symptoms.

authors

Shin YK,Kwon JG,Kim KY,Park JB,Han SJ,Cheon JW,Kim EY,Kim HG,Lee TS,Park KS,Won KS

doi

10.5056/jnm.2010.16.1.77

subject

Has Abstract

pub_date

2010-01-01 00:00:00

pages

77-82

issue

1

eissn

2093-0879

issn

2093-0887

journal_volume

16

pub_type

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