Optical Tools to Investigate Cellular Activity in the Intestinal Wall.

abstract：:Constipation in children is a common health problem affecting 0.7% to 29.6% children across the world. Exact etiology for developing symptoms is not clear in children and the majority is considered to have functional constipation. Alteration of rectal and pelvic floor function through the brain-gut axis seems to play ...

journal_title：Journal of neurogastroenterology and motility

authors： Rajindrajith S,Devanarayana NM

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND/AIMS:Despite numerous studies on the relation of genetic polymorphisms with irritable bowel syndrome (IBS), the results still remain inconclusive. The aim of this study was to assess the possible association between SLC6A4 serotonin transporter gene linked polymorphic region (5-HTTLPR), ADRA2A -1291C>G, GNB3...

journal_title：Journal of neurogastroenterology and motility

authors： Choi YJ,Hwang SW,Kim N,Park JH,Oh JC,Lee DH

更新日期：2014-07-31 00:00:00

abstract：:That gastrointestinal motility can influence the gut microbiota has been known for decades and the clinical consequences of impaired motility, in terms of the bacterial population of the small intestine, amply illustrated by the syndrome of small intestinal bacterial overgrowth which so commonly accompanies diffuse in...

journal_title：Journal of neurogastroenterology and motility

authors： Quigley EM

更新日期：2011-04-01 00:00:00

abstract：Background/Aims:The prevalence of eosinophilic esophagitis (EoE) is reportedly increasing in Western countries. However, its prevalence in Korea remains unknown. We investigated the diagnostic trends and clinical characteristics of EoE in Korea. Methods:Using an endoscopic database maintained at a tertiary care center...

journal_title：Journal of neurogastroenterology and motility

authors： Kim GH,Jung KW,Jung HY,Choi KD,Lee J,Park YS,Kim SW,Lee JH,Kim DH,Ahn JY,Song HJ,Lee GH,Kim JH

更新日期：2018-04-30 00:00:00

abstract：:The mammalian intestine contains many different cell types but is comprised of 2 main cell types: epithelial cells and smooth muscle cells. Recent in vivo and in vitro evidence has revealed that various alterations to the DNA methylation apparatus within both of these cell types can result in a variety of cellular phe...

journal_title：Journal of neurogastroenterology and motility

authors： Jorgensen BG,Ro S

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND/AIMS:Interstitial cells of Cajal (ICC) play important functions in motor activity of the gastrointestinal tract. The role of ICC as pace-makers is well established, however their participation in neurotransmission is controversial. Studies using mutant animals that lack ICC have yielded variable conclusions ...

journal_title：Journal of neurogastroenterology and motility

authors： Sanders KM,Salter AK,Hennig GW,Koh SD,Perrino BA,Ward SM,Baker SA

更新日期：2014-04-30 00:00:00

abstract：BACKGROUND/AIMS:Irritable bowel syndrome (IBS) is one of the most frequently observed disorders by primary care and practitioners. The aim of this study was to estimate the prevalence of IBS using the Rome II and III criteria in the general Korean population and also to compare sociodemographic differences between subj...

journal_title：Journal of neurogastroenterology and motility

authors： Park DW,Lee OY,Shim SG,Jun DW,Lee KN,Kim HY,Lee HL,Yoon BC,Choi HS

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND/AIMS:To evaluate the effects of the phosphodiesterase type 5 (PDE5) inhibitor vardenafil on esophageal function, including bolus transit, using multichannel intraluminal impedance and esophageal manometry (MII-EM). METHODS:Sixteen healthy volunteers (15 men) underwent an MII-EM study including 10 liquid swa...

journal_title：Journal of neurogastroenterology and motility

authors： Lee TH,Lee JS,Hong SJ,Jeon SR,Kim WJ,Kim HG,Cho JY,Kim JO

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND/AIMS:Transient lower esophageal sphincter relaxation (TLESR) is the main mechanism of gastroesophageal reflux disease (GERD). The aim of this study was to investigate the characteristics of transient lower esophageal sphincter movement in patients with or without gastroesophageal reflux by high-resolution ma...

journal_title：Journal of neurogastroenterology and motility

authors： Kim HI,Hong SJ,Han JP,Seo JY,Hwang KH,Maeng HJ,Lee TH,Lee JS

更新日期：2013-07-01 00:00:00

abstract：Background/Aims:Self-reported lactose intolerance (LI) is frequent in patients with functional bowel disorders (FBD) that could be interpreted as irritable bowel syndrome (IBS). The present study aims to characterize the responses of FBD patients without small intestinal bacterial overgrowth (SIBO), and LI, in terms of...

journal_title：Journal of neurogastroenterology and motility

authors： Bouchoucha M,Fysekidis M,Rompteaux P,Raynaud JJ,Sabate JM,Benamouzig R

更新日期：2020-12-28 00:00:00

abstract：BACKGROUND/AIMS:Antispasmodics including otilonium bromide (OB) are recommended to treat irritable bowel syndrome (IBS). However, reports about OB experience in Asia is sparse. The purpose of present study was to provide the efficacy of OB in treating Asian IBS patients. METHODS:Overall, 117 IBS patients meeting Rome ...

journal_title：Journal of neurogastroenterology and motility

authors： Chang FY,Lu CL,Luo JC,Chen TS,Chen MJ,Chang HJ

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND/AIMS:Gastroparesis-like syndrome (GLS) is defined as gastroparesis-like symptoms with normal gastric scintigraphy. While the efficacy of gastric electrical stimulation (GES) in gastroparesis is well known, the utility of GES in GLS is largely unknown. Our aim was to clarify the role of GES in GLS. We implant...

journal_title：Journal of neurogastroenterology and motility

authors： Singh S,McCrary J,Kedar A,Weeks S,Beauerle B,Weeks A,Endashaw O,Lahr C,Starkebaum W,Abell T

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND/AIMS:Rome criteria classifying functional gastrointestinal disorder (FGID) were updated. The aims of this study were to assess the spectra of FGID and to evaluate the applicability of Rome III criteria in Korea. METHODS:New patients who visited 2 primary clinics and 2 tertiary care hospitals were consecutiv...

journal_title：Journal of neurogastroenterology and motility

authors： Park JM,Choi MG,Cho YK,Lee IS,Kim JI,Kim SW,Chung IS

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND/AIMS:Functional dyspepsia (FD) is one of the commonest diseases in the field of Internal Medicine. The Japanese Society of Gastroenterology (JSGE) has been enlightening the term and concept of FD. Aim of this survey was to elucidate the understanding status of FD and Rome criteria and attitude toward FD amon...

journal_title：Journal of neurogastroenterology and motility

authors： Kaneko H,Tsuboi H

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND/AIMS:Irritable bowel syndrome (IBS) is a widespread chronic health condition which is significantly more prevalent in women. We conducted a gender difference analysis by comparing findings of men and women to determine whether any significant differences exist or not. METHODS:This single-center study was co...

journal_title：Journal of neurogastroenterology and motility

authors： Anbardan SJ,Daryani NE,Fereshtehnejad SM,Taba Taba Vakili S,Keramati MR,Ajdarkosh H

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND/AIMS:Gastrointestinal symptoms and hypothalamus-pituitary-adrenal (HPA) axis dysfunction are frequently observed in patients with major depression. The primary aim of the study was to investigate the relationship between HPA-axis function and self-perceived functional gastrointestinal symptoms in major depre...

journal_title：Journal of neurogastroenterology and motility

authors： Karling P,Wikgren M,Adolfsson R,Norrback KF

更新日期：2016-04-30 00:00:00

abstract：:Irritable bowel syndrome (IBS) has been one of the commonly presented gastrointestinal disorders. It is of interest how commonly it presents in the society. Western studies indicated that most population-based IBS prevalences range 10%-15%. It is believed that IBS is prevalent in both East and West countries without a...

journal_title：Journal of neurogastroenterology and motility

authors： Chang FY,Lu CL,Chen TS

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND/AIMS:The marketing of newer agents for treatment of constipation and irritable bowel syndrome with constipation (IBS-C) emphasize improvements in abdominal pain. However, it is not clear whether this observation reflects a unique visceral analgesic effect of these agents or is a general feature of effective ...

journal_title：Journal of neurogastroenterology and motility

authors： Bielefeldt K,Levinthal DJ,Nusrat S

更新日期：2016-01-31 00:00:00

abstract：Background/Aims:Functional dyspepsia (FD) is characterized as chronic recurrent upper gastrointestinal symptoms in the absence of any organic disorder. We hypothesized that duodenal low-grade inflammation activates superficial afferent nerve sprouting, thereby contributing to hypersensitivity in patients with FD. Meth...

journal_title：Journal of neurogastroenterology and motility

authors： Lee MJ,Jung HK,Lee KE,Mun YC,Park S

更新日期：2019-04-30 00:00:00

abstract：Background/Aims:Current evidence suggests the presence of motility or functional abnormalities in one area of the gastrointestinal tract increases the likelihood of abnormalities in others. However, the relationship of gastroparesis to chronic constipation (slow transit constipation and dyssynergic defecation) has been...

journal_title：Journal of neurogastroenterology and motility

authors： Zikos TA,Kamal AN,Neshatian L,Triadafilopoulos G,Clarke JO,Nandwani M,Nguyen LA

更新日期：2019-04-30 00:00:00

abstract：BACKGROUND/AIMS:In isolated guinea-pig colon, we investigated regional differences in peristalsis evoked by intrinsic electrical nerve stimulation. METHODS:Four colonic segments from mid and distal colon of Hartley guinea pigs, were mounted horizontally in an organ bath. Measurement of pellet propulsion time, intralum...

journal_title：Journal of neurogastroenterology and motility

authors： Kwak JM,Babygirija R,Gribovskaja-Rupp I,Takahashi T,Yamato S,Ludwig K

更新日期：2013-04-01 00:00:00

abstract：Background/Aims:Recent studies suggest that air pollution may play a role in gastrointestinal disorders. However, the effect of long-term exposure to air pollution on childhood irritable bowel syndrome (IBS) is unclear. Hence, we conducted a nationwide cohort study to investigate the association between long-term air p...

journal_title：Journal of neurogastroenterology and motility

authors： Tan TK,Saps M,Lin CL,Wei CC

更新日期：2019-04-30 00:00:00

abstract：BACKGROUND/AIMS:Several motility disorders are associated with disruption of interstitial cells of Cajal (ICC), which provide important functions, such as pacemaker activity, mediation of neural inputs and responses to stretch in the gastrointestinal (GI) tract. Restoration of ICC networks may be therapeutic for GI mot...

journal_title：Journal of neurogastroenterology and motility

authors： McCann CJ,Hwang SJ,Hennig GW,Ward SM,Sanders KM

更新日期：2014-07-31 00:00:00

abstract：:This article highlights the role of prucalopride in the management of chronic constipation based upon the principles of meta-analysis using data reported in the published randomized, controlled trials. Sixteen randomized, controlled trials on 3943 patients reported the effectiveness of prucalopride in patients with ch...

journal_title：Journal of neurogastroenterology and motility

authors： Sajid MS,Hebbar M,Baig MK,Li A,Philipose Z

更新日期：2016-07-30 00:00:00

abstract：BACKGROUND/AIMS:While it is well established that acupuncture relieves somatic pain, its therapeutic effect on visceral pain such as irritable bowel syndrome (IBS) is unclear. We evaluated the effect of acupuncture in treating visceral hyperalgesia in an animal model. METHODS:Sprague-Dawley rats (n = 8 per group) with...

journal_title：Journal of neurogastroenterology and motility

authors： Wu JC,Ziea ET,Lao L,Lam EF,Chan CS,Liang AY,Chu SL,Yew DT,Berman BM,Sung JJ

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND/AIMS:Solifenacin, a muscarinic type 3 receptor antagonist, is used to treat overactive bladder in adults. The aim of this study is to examine the efficacy of solifenacin on the symptomatic relief of diarrhea predominant irritable bowel syndrome (IBS-D). METHODS:A total of 20 patients with IBS-D were enrolle...

journal_title：Journal of neurogastroenterology and motility

authors： Fukushima Y,Suzuki H,Matsuzaki J,Kiyosue A,Hibi T

更新日期：2012-07-01 00:00:00

abstract：Background/Aims:The prevalence and severity of irritable bowel syndrome (IBS) declines with age, but the cause of this is unknown. This study tested 2 hypotheses: (1) autonomic nervous system responses to eating and bowel distention, measured by heart rate variability (HRV), differs by age in IBS patients and (2) HRV i...

journal_title：Journal of neurogastroenterology and motility

authors： Tanaka Y,Kanazawa M,Palsson OS,Tilburg MAV,Gangarosa LM,Fukudo S,Drossman DA,Whitehead WE

更新日期：2018-01-30 00:00:00

abstract：:Author's name was mis-typed. The name "Oya B Sezer" in the original article should have been written as "Oya Balcı Sezer." ...

journal_title：Journal of neurogastroenterology and motility

authors： Sezer OB,Sezer T

更新日期：2019-01-31 00:00:00

abstract：BACKGROUND/AIMS:Rats with a spontaneous null mutation in endothelin receptor type B or Ednrb (sl/sl; spotting lethal) lack enteric neurons in the distal bowel and usually die within the first week after birth. This early postnatal lethality limits their use for examining the potential of cell therapy to treat Hirschspr...

journal_title：Journal of neurogastroenterology and motility

authors： Stamp LA,Obermayr F,Pontell L,Young HM,Xie D,Croaker DH,Song ZM,Furness JB

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND/AIMS:Approximately one-third of non-erosive reflux disease (NERD) patients are refractory to proton pump inhibitors (PPI) and face a therapeutic challenge. Therefore, it is important to differentiate between pathological and non-pathological reflux utilizing multichannel intraluminal impedance-pH (MII-pH) to...

journal_title：Journal of neurogastroenterology and motility

authors： Khan MQ,Alaraj A,Alsohaibani F,Al-Kahtani K,Jbarah S,Al-Ashgar H

更新日期：2014-10-30 00:00:00