Degranulated Eosinophils Contain More Fine Nerve Fibers in the Duodenal Mucosa of Patients With Functional Dyspepsia.

abstract：:Gastroesophageal reflux disease (GERD) is a very common disease, and the prevalence in the general population has recently increased. GERD is a chronic relapsing disease associated with motility disorders of the upper gastrointestinal tract. Several factors are implicated in GERD, including hypotensive lower esophagea...

journal_title：Journal of neurogastroenterology and motility

authors： Lin S,Li H,Fang X

更新日期：2019-10-30 00:00:00

abstract：BACKGROUND/AIMS:To draw a normative database of laryngopharynx pH profile in Chinese subjects. METHODS:Normal volunteers were recruited from "www.Ganji.com" and People's hospital between May 2008 and December 2009. The Restech pH Probes were calibrated in pH 7 and pH 4 buffer solutions according to the manufacturer's ...

journal_title：Journal of neurogastroenterology and motility

authors： Feng G,Wang J,Zhang L,Liu Y

更新日期：2014-07-31 00:00:00

abstract：BACKGROUND/AIMS:Interstitial cells of Cajal (ICC) play important functions in motor activity of the gastrointestinal tract. The role of ICC as pace-makers is well established, however their participation in neurotransmission is controversial. Studies using mutant animals that lack ICC have yielded variable conclusions ...

journal_title：Journal of neurogastroenterology and motility

authors： Sanders KM,Salter AK,Hennig GW,Koh SD,Perrino BA,Ward SM,Baker SA

更新日期：2014-04-30 00:00:00

abstract：Background/Aims:Nutrient-induced gut hormone release (eg, cholecystokinin [CCK]) and the modulation of gut motility (particularly pyloric stimulation) contribute to the regulation of acute energy intake. Non-caloric bitter compounds, including quinine, have recently been shown in cell-line and animal studies to stimula...

journal_title：Journal of neurogastroenterology and motility

authors： Bitarafan V,Fitzgerald PCE,Little TJ,Meyerhof W,Wu T,Horowitz M,Feinle-Bisset C

更新日期：2019-07-01 00:00:00

abstract：:Radiofrequency catheter ablation (RFCA) is a potentially curative method for treatment of highly symptomatic and drug-refractory atrial fibrillation (AF). However, this technique can provoke esophageal and nerve lesion, due to thermal injury. To our knowledge, there have been no reported cases of a newly described mot...

journal_title：Journal of neurogastroenterology and motility

authors： Tolone S,Savarino E,Docimo L

更新日期：2015-10-01 00:00:00

abstract：Background/Aims:Irritable bowel syndrome (IBS) is a common disease characterized by intestinal dysmotility, the mechanism of which remains elusive. We aim to determine whether the high-affinity choline transporter 1 (CHT1), a determinant of cholinergic signaling capacity, modulates intestinal motility associated with s...

journal_title：Journal of neurogastroenterology and motility

authors： Lin MJ,Yu BP

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND/AIMS:Functional gastrointestinal disorders (FGIDs), diagnosed by symptom-based criteria due to lack of biomarkers, need translatedvalidated questionnaires in different languages. As Bengali, the mother tongue of Bangladesh and eastern India, is the seventh most spoken language in the world, we translated and...

journal_title：Journal of neurogastroenterology and motility

authors： Rahman MM,Ghoshal UC,Rowshon AH,Ahmed F,Kibria MG,Hasan M,Gwee KA,Whitehead WE

更新日期：2016-04-30 00:00:00

abstract：BACKGROUND/AIMS:Functional dyspepsia (FD) is one of the commonest diseases in the field of Internal Medicine. The Japanese Society of Gastroenterology (JSGE) has been enlightening the term and concept of FD. Aim of this survey was to elucidate the understanding status of FD and Rome criteria and attitude toward FD amon...

journal_title：Journal of neurogastroenterology and motility

authors： Kaneko H,Tsuboi H

更新日期：2014-01-01 00:00:00

abstract：Background/Aims:Currently, there exists no biomarker for visceral hypersensitivity in irritable bowel syndrome (IBS). Piezo proteins have been proven to play an important role in the mechanical stimulation to induce visceral pain in other tissues and may also be a biomarker candidate. The aim of this study was to test ...

journal_title：Journal of neurogastroenterology and motility

authors： Bai T,Li Y,Xia J,Jiang Y,Zhang L,Wang H,Qian W,Song J,Hou X

更新日期：2017-07-30 00:00:00

abstract：Background/Aims:Integrated relaxation pressure (IRP) is defined as the average minimum esophagogastric junction (EGJ) pressure for 4 seconds of relaxation (contiguous or noncontiguous) within 10 seconds of swallowing. The durability of IRP values during successive swallows in the supine position remains to be elucidate...

journal_title：Journal of neurogastroenterology and motility

authors： Elangovan A,Shibli F,Fass R

更新日期：2021-01-28 00:00:00

abstract：:An increase in intracellular Ca(2+) is the primary trigger of contraction of gastrointestinal (GI) smooth muscles. However, increasing the Ca(2+) sensitivity of the myofilaments by elevating myosin light chain phosphorylation also plays an essential role. Inhibiting myosin light chain phosphatase activity with protein...

journal_title：Journal of neurogastroenterology and motility

authors： Perrino BA

更新日期：2016-04-30 00:00:00

abstract：Background/Aims:Since the use of dexlansoprazole in Asian subjects with gastroesophageal reflux disease (GERD) has not been adequately characterized, this study was conducted to evaluate the efficacy and safety of dexlansoprazole modified-release in Asian subjects with non-erosive reflux disease (NERD) and erosive esop...

journal_title：Journal of neurogastroenterology and motility

authors： Wu JCY,Sheu BS,Wu MS,Lee YC,Choi MG

更新日期：2020-01-30 00:00:00

abstract：BACKGROUND/AIMS:Transient lower esophageal sphincter relaxation (TLESR) is the main mechanism of gastroesophageal reflux disease (GERD). The aim of this study was to investigate the characteristics of transient lower esophageal sphincter movement in patients with or without gastroesophageal reflux by high-resolution ma...

journal_title：Journal of neurogastroenterology and motility

authors： Kim HI,Hong SJ,Han JP,Seo JY,Hwang KH,Maeng HJ,Lee TH,Lee JS

更新日期：2013-07-01 00:00:00

abstract：Background/Aims:Recent studies suggest that air pollution may play a role in gastrointestinal disorders. However, the effect of long-term exposure to air pollution on childhood irritable bowel syndrome (IBS) is unclear. Hence, we conducted a nationwide cohort study to investigate the association between long-term air p...

journal_title：Journal of neurogastroenterology and motility

authors： Tan TK,Saps M,Lin CL,Wei CC

更新日期：2019-04-30 00:00:00

abstract：:Author's name was mis-typed. The name "Oya B Sezer" in the original article should have been written as "Oya Balcı Sezer." ...

journal_title：Journal of neurogastroenterology and motility

authors： Sezer OB,Sezer T

更新日期：2019-01-31 00:00:00

abstract：BACKGROUND/AIMS:To evaluate the effects of the phosphodiesterase type 5 (PDE5) inhibitor vardenafil on esophageal function, including bolus transit, using multichannel intraluminal impedance and esophageal manometry (MII-EM). METHODS:Sixteen healthy volunteers (15 men) underwent an MII-EM study including 10 liquid swa...

journal_title：Journal of neurogastroenterology and motility

authors： Lee TH,Lee JS,Hong SJ,Jeon SR,Kim WJ,Kim HG,Cho JY,Kim JO

更新日期：2012-10-01 00:00:00

abstract：:Live imaging has become an essential tool to investigate the coordinated activity and output of cellular networks. Within the last decade, 2 Nobel prizes have been awarded to recognize innovations in the field of imaging: one for the discovery, use, and optimization of the green fluorescent protein (2008) and the seco...

journal_title：Journal of neurogastroenterology and motility

authors： Boesmans W,Hao MM,Vanden Berghe P

更新日期：2015-07-30 00:00:00

abstract：BACKGROUND/AIMS:Despite numerous studies on the relation of genetic polymorphisms with irritable bowel syndrome (IBS), the results still remain inconclusive. The aim of this study was to assess the possible association between SLC6A4 serotonin transporter gene linked polymorphic region (5-HTTLPR), ADRA2A -1291C>G, GNB3...

journal_title：Journal of neurogastroenterology and motility

authors： Choi YJ,Hwang SW,Kim N,Park JH,Oh JC,Lee DH

更新日期：2014-07-31 00:00:00

abstract：Background/Aims:The prevalence and severity of irritable bowel syndrome (IBS) declines with age, but the cause of this is unknown. This study tested 2 hypotheses: (1) autonomic nervous system responses to eating and bowel distention, measured by heart rate variability (HRV), differs by age in IBS patients and (2) HRV i...

journal_title：Journal of neurogastroenterology and motility

authors： Tanaka Y,Kanazawa M,Palsson OS,Tilburg MAV,Gangarosa LM,Fukudo S,Drossman DA,Whitehead WE

更新日期：2018-01-30 00:00:00

abstract：BACKGROUND/AIMS:Gastroparesis-like syndrome (GLS) is defined as gastroparesis-like symptoms with normal gastric scintigraphy. While the efficacy of gastric electrical stimulation (GES) in gastroparesis is well known, the utility of GES in GLS is largely unknown. Our aim was to clarify the role of GES in GLS. We implant...

journal_title：Journal of neurogastroenterology and motility

authors： Singh S,McCrary J,Kedar A,Weeks S,Beauerle B,Weeks A,Endashaw O,Lahr C,Starkebaum W,Abell T

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND/AIMS:Irritable bowel syndrome (IBS) is a widespread chronic health condition which is significantly more prevalent in women. We conducted a gender difference analysis by comparing findings of men and women to determine whether any significant differences exist or not. METHODS:This single-center study was co...

journal_title：Journal of neurogastroenterology and motility

authors： Anbardan SJ,Daryani NE,Fereshtehnejad SM,Taba Taba Vakili S,Keramati MR,Ajdarkosh H

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND/AIMS:Antispasmodics including otilonium bromide (OB) are recommended to treat irritable bowel syndrome (IBS). However, reports about OB experience in Asia is sparse. The purpose of present study was to provide the efficacy of OB in treating Asian IBS patients. METHODS:Overall, 117 IBS patients meeting Rome ...

journal_title：Journal of neurogastroenterology and motility

authors： Chang FY,Lu CL,Luo JC,Chen TS,Chen MJ,Chang HJ

更新日期：2011-10-01 00:00:00

abstract：:The mammalian intestine contains many different cell types but is comprised of 2 main cell types: epithelial cells and smooth muscle cells. Recent in vivo and in vitro evidence has revealed that various alterations to the DNA methylation apparatus within both of these cell types can result in a variety of cellular phe...

journal_title：Journal of neurogastroenterology and motility

authors： Jorgensen BG,Ro S

更新日期：2019-07-01 00:00:00

abstract：Background/Aims:Lipopolysaccharide (LPS) is the key factor inducing mucosal and systemic inflammation in various intestinal and parenteral diseases, which could initially disrupt the epithelial barrier function. EphrinA1/ephA2 is speculated to increase the epithelial permeability for its "repulsive interaction" between...

journal_title：Journal of neurogastroenterology and motility

authors： Chen Y,Zhang L,Zhang Y,Bai T,Song J,Qian W,Hou X

更新日期：2020-07-30 00:00:00

abstract：Background/Aims:High-resolution manometry (HRM) has broadened the awareness of minor esophageal peristaltic disorders. However, the treatments for these minor disorders are limited and the role of prokinetics has been controversial. This study evaluates the effect of mosapride in patients with minor peristaltic disorde...

journal_title：Journal of neurogastroenterology and motility

authors： Kim SE,Park MI,Park SJ,Moon W,Kim JH,Jung K,Kwon HJ,Kim GM,Joo HK

更新日期：2020-04-30 00:00:00

abstract：:That gastrointestinal motility can influence the gut microbiota has been known for decades and the clinical consequences of impaired motility, in terms of the bacterial population of the small intestine, amply illustrated by the syndrome of small intestinal bacterial overgrowth which so commonly accompanies diffuse in...

journal_title：Journal of neurogastroenterology and motility

authors： Quigley EM

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND/AIMS:Gastrointestinal symptoms and hypothalamus-pituitary-adrenal (HPA) axis dysfunction are frequently observed in patients with major depression. The primary aim of the study was to investigate the relationship between HPA-axis function and self-perceived functional gastrointestinal symptoms in major depre...

journal_title：Journal of neurogastroenterology and motility

authors： Karling P,Wikgren M,Adolfsson R,Norrback KF

更新日期：2016-04-30 00:00:00

abstract：:Irritable bowel syndrome (IBS) has been one of the commonly presented gastrointestinal disorders. It is of interest how commonly it presents in the society. Western studies indicated that most population-based IBS prevalences range 10%-15%. It is believed that IBS is prevalent in both East and West countries without a...

journal_title：Journal of neurogastroenterology and motility

authors： Chang FY,Lu CL,Chen TS

更新日期：2010-10-01 00:00:00

abstract：Background/Aims:The prevalence of eosinophilic esophagitis (EoE) is reportedly increasing in Western countries. However, its prevalence in Korea remains unknown. We investigated the diagnostic trends and clinical characteristics of EoE in Korea. Methods:Using an endoscopic database maintained at a tertiary care center...

journal_title：Journal of neurogastroenterology and motility

authors： Kim GH,Jung KW,Jung HY,Choi KD,Lee J,Park YS,Kim SW,Lee JH,Kim DH,Ahn JY,Song HJ,Lee GH,Kim JH

更新日期：2018-04-30 00:00:00

abstract：Background/Aims:Probiotics are expected to modify the composition of gut microbiota. We aimed to investigate the changes in the composition and diversity of gut microbiota by the administration of probiotics in healthy individuals. Methods:Twelve healthy volunteers with age range of 30-42 years provided baseline fecal...

journal_title：Journal of neurogastroenterology and motility

authors： Noh CK,Kim BS,Hong G,Cheong JY,Lee KJ

更新日期：2018-07-30 00:00:00