Increased Postprandial Colonic Motility and Autonomic Nervous System Activity in Patients With Irritable Bowel Syndrome: A Prospective Study.

abstract：BACKGROUND/AIMS:Solifenacin, a muscarinic type 3 receptor antagonist, is used to treat overactive bladder in adults. The aim of this study is to examine the efficacy of solifenacin on the symptomatic relief of diarrhea predominant irritable bowel syndrome (IBS-D). METHODS:A total of 20 patients with IBS-D were enrolle...

journal_title：Journal of neurogastroenterology and motility

authors： Fukushima Y,Suzuki H,Matsuzaki J,Kiyosue A,Hibi T

更新日期：2012-07-01 00:00:00

abstract：Background/Aims:Self-reported lactose intolerance (LI) is frequent in patients with functional bowel disorders (FBD) that could be interpreted as irritable bowel syndrome (IBS). The present study aims to characterize the responses of FBD patients without small intestinal bacterial overgrowth (SIBO), and LI, in terms of...

journal_title：Journal of neurogastroenterology and motility

authors： Bouchoucha M,Fysekidis M,Rompteaux P,Raynaud JJ,Sabate JM,Benamouzig R

更新日期：2020-12-28 00:00:00

abstract：BACKGROUND/AIMS:Irritable bowel syndrome (IBS) is a widespread chronic health condition which is significantly more prevalent in women. We conducted a gender difference analysis by comparing findings of men and women to determine whether any significant differences exist or not. METHODS:This single-center study was co...

journal_title：Journal of neurogastroenterology and motility

authors： Anbardan SJ,Daryani NE,Fereshtehnejad SM,Taba Taba Vakili S,Keramati MR,Ajdarkosh H

更新日期：2012-01-01 00:00:00

abstract：:Constipation in children is a common health problem affecting 0.7% to 29.6% children across the world. Exact etiology for developing symptoms is not clear in children and the majority is considered to have functional constipation. Alteration of rectal and pelvic floor function through the brain-gut axis seems to play ...

journal_title：Journal of neurogastroenterology and motility

authors： Rajindrajith S,Devanarayana NM

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND/AIMS:Functional gastrointestinal disorders (FGIDs), diagnosed by symptom-based criteria due to lack of biomarkers, need translatedvalidated questionnaires in different languages. As Bengali, the mother tongue of Bangladesh and eastern India, is the seventh most spoken language in the world, we translated and...

journal_title：Journal of neurogastroenterology and motility

authors： Rahman MM,Ghoshal UC,Rowshon AH,Ahmed F,Kibria MG,Hasan M,Gwee KA,Whitehead WE

更新日期：2016-04-30 00:00:00

abstract：:This article highlights the role of prucalopride in the management of chronic constipation based upon the principles of meta-analysis using data reported in the published randomized, controlled trials. Sixteen randomized, controlled trials on 3943 patients reported the effectiveness of prucalopride in patients with ch...

journal_title：Journal of neurogastroenterology and motility

authors： Sajid MS,Hebbar M,Baig MK,Li A,Philipose Z

更新日期：2016-07-30 00:00:00

abstract：:Author's name was mis-typed. The name "Oya B Sezer" in the original article should have been written as "Oya Balcı Sezer." ...

journal_title：Journal of neurogastroenterology and motility

authors： Sezer OB,Sezer T

更新日期：2019-01-31 00:00:00

abstract：:Assessment of transit through the gastrointestinal tract provides useful information regarding gut physiology and patho-physiology. Although several methods are available, each has distinct advantages and limitations. Recently, an ingestible wire-less motility capsule (WMC), similar to capsule video endoscopy, has bec...

journal_title：Journal of neurogastroenterology and motility

authors： Lee YY,Erdogan A,Rao SS

更新日期：2014-04-30 00:00:00

abstract：:That gastrointestinal motility can influence the gut microbiota has been known for decades and the clinical consequences of impaired motility, in terms of the bacterial population of the small intestine, amply illustrated by the syndrome of small intestinal bacterial overgrowth which so commonly accompanies diffuse in...

journal_title：Journal of neurogastroenterology and motility

authors： Quigley EM

更新日期：2011-04-01 00:00:00

abstract：:Gastroesophageal reflux disease (GERD) is a very common disease, and the prevalence in the general population has recently increased. GERD is a chronic relapsing disease associated with motility disorders of the upper gastrointestinal tract. Several factors are implicated in GERD, including hypotensive lower esophagea...

journal_title：Journal of neurogastroenterology and motility

authors： Lin S,Li H,Fang X

更新日期：2019-10-30 00:00:00

abstract：BACKGROUND/AIMS:To evaluate the effects of the phosphodiesterase type 5 (PDE5) inhibitor vardenafil on esophageal function, including bolus transit, using multichannel intraluminal impedance and esophageal manometry (MII-EM). METHODS:Sixteen healthy volunteers (15 men) underwent an MII-EM study including 10 liquid swa...

journal_title：Journal of neurogastroenterology and motility

authors： Lee TH,Lee JS,Hong SJ,Jeon SR,Kim WJ,Kim HG,Cho JY,Kim JO

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND/AIMS:In isolated guinea-pig colon, we investigated regional differences in peristalsis evoked by intrinsic electrical nerve stimulation. METHODS:Four colonic segments from mid and distal colon of Hartley guinea pigs, were mounted horizontally in an organ bath. Measurement of pellet propulsion time, intralum...

journal_title：Journal of neurogastroenterology and motility

authors： Kwak JM,Babygirija R,Gribovskaja-Rupp I,Takahashi T,Yamato S,Ludwig K

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND/AIMS:Transient lower esophageal sphincter relaxation (TLESR) is the main mechanism of gastroesophageal reflux disease (GERD). The aim of this study was to investigate the characteristics of transient lower esophageal sphincter movement in patients with or without gastroesophageal reflux by high-resolution ma...

journal_title：Journal of neurogastroenterology and motility

authors： Kim HI,Hong SJ,Han JP,Seo JY,Hwang KH,Maeng HJ,Lee TH,Lee JS

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND/AIMS:Irritable bowel syndrome (IBS) is one of the most frequently observed disorders by primary care and practitioners. The aim of this study was to estimate the prevalence of IBS using the Rome II and III criteria in the general Korean population and also to compare sociodemographic differences between subj...

journal_title：Journal of neurogastroenterology and motility

authors： Park DW,Lee OY,Shim SG,Jun DW,Lee KN,Kim HY,Lee HL,Yoon BC,Choi HS

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND/AIMS:Several motility disorders are associated with disruption of interstitial cells of Cajal (ICC), which provide important functions, such as pacemaker activity, mediation of neural inputs and responses to stretch in the gastrointestinal (GI) tract. Restoration of ICC networks may be therapeutic for GI mot...

journal_title：Journal of neurogastroenterology and motility

authors： McCann CJ,Hwang SJ,Hennig GW,Ward SM,Sanders KM

更新日期：2014-07-31 00:00:00

abstract：Background/Aims:Nausea, an unpleasant symptom of diabetic gastroparesis (DMGP), has been reported to be alleviated by needleless transcutaneous electrical acupuncture (TEA). Our study was designed to utilize electroencephalography (EEG) and electrogastrography (EGG) recordings to investigate the central and peripheral ...

journal_title：Journal of neurogastroenterology and motility

authors： Sarosiek I,Song G,Sun Y,Sandoval H,Sands S,Chen J,McCallum RW

更新日期：2017-04-30 00:00:00

abstract：Background/Aims:Irritable bowel syndrome (IBS) is a common disease characterized by intestinal dysmotility, the mechanism of which remains elusive. We aim to determine whether the high-affinity choline transporter 1 (CHT1), a determinant of cholinergic signaling capacity, modulates intestinal motility associated with s...

journal_title：Journal of neurogastroenterology and motility

authors： Lin MJ,Yu BP

更新日期：2018-10-01 00:00:00

abstract：Background/Aims:Probiotics are expected to modify the composition of gut microbiota. We aimed to investigate the changes in the composition and diversity of gut microbiota by the administration of probiotics in healthy individuals. Methods:Twelve healthy volunteers with age range of 30-42 years provided baseline fecal...

journal_title：Journal of neurogastroenterology and motility

authors： Noh CK,Kim BS,Hong G,Cheong JY,Lee KJ

更新日期：2018-07-30 00:00:00

abstract：BACKGROUND/AIMS:The marketing of newer agents for treatment of constipation and irritable bowel syndrome with constipation (IBS-C) emphasize improvements in abdominal pain. However, it is not clear whether this observation reflects a unique visceral analgesic effect of these agents or is a general feature of effective ...

journal_title：Journal of neurogastroenterology and motility

authors： Bielefeldt K,Levinthal DJ,Nusrat S

更新日期：2016-01-31 00:00:00

abstract：Background/Aims:Current evidence suggests the presence of motility or functional abnormalities in one area of the gastrointestinal tract increases the likelihood of abnormalities in others. However, the relationship of gastroparesis to chronic constipation (slow transit constipation and dyssynergic defecation) has been...

journal_title：Journal of neurogastroenterology and motility

authors： Zikos TA,Kamal AN,Neshatian L,Triadafilopoulos G,Clarke JO,Nandwani M,Nguyen LA

更新日期：2019-04-30 00:00:00

abstract：Background/Aims:Interstitial cells play important roles in gastrointestinal (GI) neuro-smooth muscle transmission. The underlying mechanisms of colonic dysmotility have not been well illustrated. We established a partial colon obstruction (PCO) mouse model to investigate the changes of interstitial cells and the correl...

journal_title：Journal of neurogastroenterology and motility

authors： Wang Q,Zang J,Huang X,Lu H,Xu W,Chen J

更新日期：2019-10-30 00:00:00

abstract：BACKGROUND/AIMS:Antispasmodics including otilonium bromide (OB) are recommended to treat irritable bowel syndrome (IBS). However, reports about OB experience in Asia is sparse. The purpose of present study was to provide the efficacy of OB in treating Asian IBS patients. METHODS:Overall, 117 IBS patients meeting Rome ...

journal_title：Journal of neurogastroenterology and motility

authors： Chang FY,Lu CL,Luo JC,Chen TS,Chen MJ,Chang HJ

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND/AIMS:Proton pump inhibitors (PPIs) which are the most effective agents for the treatment of gastroesophageal reflux disease (GERD), have been known to delay gastric emptying. Mosapride has been used as prokinetics by accelerating gastric emptying. We evaluated the efficacy of mosapride to prevent PPI-induced...

journal_title：Journal of neurogastroenterology and motility

authors： Lim HC,Kim JH,Youn YH,Lee EH,Lee BK,Park H

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND/AIMS:Gastrointestinal symptoms and hypothalamus-pituitary-adrenal (HPA) axis dysfunction are frequently observed in patients with major depression. The primary aim of the study was to investigate the relationship between HPA-axis function and self-perceived functional gastrointestinal symptoms in major depre...

journal_title：Journal of neurogastroenterology and motility

authors： Karling P,Wikgren M,Adolfsson R,Norrback KF

更新日期：2016-04-30 00:00:00

abstract：BACKGROUND/AIMS:Interstitial cells of Cajal (ICC) play important functions in motor activity of the gastrointestinal tract. The role of ICC as pace-makers is well established, however their participation in neurotransmission is controversial. Studies using mutant animals that lack ICC have yielded variable conclusions ...

journal_title：Journal of neurogastroenterology and motility

authors： Sanders KM,Salter AK,Hennig GW,Koh SD,Perrino BA,Ward SM,Baker SA

更新日期：2014-04-30 00:00:00

abstract：BACKGROUND/AIMS:Approximately one-third of non-erosive reflux disease (NERD) patients are refractory to proton pump inhibitors (PPI) and face a therapeutic challenge. Therefore, it is important to differentiate between pathological and non-pathological reflux utilizing multichannel intraluminal impedance-pH (MII-pH) to...

journal_title：Journal of neurogastroenterology and motility

authors： Khan MQ,Alaraj A,Alsohaibani F,Al-Kahtani K,Jbarah S,Al-Ashgar H

更新日期：2014-10-30 00:00:00

abstract：Background/Aims:Currently, there exists no biomarker for visceral hypersensitivity in irritable bowel syndrome (IBS). Piezo proteins have been proven to play an important role in the mechanical stimulation to induce visceral pain in other tissues and may also be a biomarker candidate. The aim of this study was to test ...

journal_title：Journal of neurogastroenterology and motility

authors： Bai T,Li Y,Xia J,Jiang Y,Zhang L,Wang H,Qian W,Song J,Hou X

更新日期：2017-07-30 00:00:00

abstract：BACKGROUND/AIMS:Recent studies reveal that acute gastroenteritis can precipitate irritable bowel syndrome (IBS) symptoms leading to the concept of post-infectious IBS. However, the overall contribution of gastroenteritis to the total IBS prevalence is unknown. In this exercise we try to estimate the contribution of gas...

journal_title：Journal of neurogastroenterology and motility

authors： Shah ED,Riddle MS,Chang C,Pimentel M

更新日期：2012-04-01 00:00:00

abstract：Background/Aims:Recent studies suggest that air pollution may play a role in gastrointestinal disorders. However, the effect of long-term exposure to air pollution on childhood irritable bowel syndrome (IBS) is unclear. Hence, we conducted a nationwide cohort study to investigate the association between long-term air p...

journal_title：Journal of neurogastroenterology and motility

authors： Tan TK,Saps M,Lin CL,Wei CC

更新日期：2019-04-30 00:00:00

abstract：Background/Aims:High-resolution manometry (HRM) has broadened the awareness of minor esophageal peristaltic disorders. However, the treatments for these minor disorders are limited and the role of prokinetics has been controversial. This study evaluates the effect of mosapride in patients with minor peristaltic disorde...

journal_title：Journal of neurogastroenterology and motility

authors： Kim SE,Park MI,Park SJ,Moon W,Kim JH,Jung K,Kwon HJ,Kim GM,Joo HK

更新日期：2020-04-30 00:00:00