Is Long-term Ambient Air Pollutant Exposure a Risk Factor for Irritable Bowel Syndrome in Children? A 12-year Longitudinal Cohort Study.

abstract：BACKGROUND/AIMS:Gastroparesis-like syndrome (GLS) is defined as gastroparesis-like symptoms with normal gastric scintigraphy. While the efficacy of gastric electrical stimulation (GES) in gastroparesis is well known, the utility of GES in GLS is largely unknown. Our aim was to clarify the role of GES in GLS. We implant...

journal_title：Journal of neurogastroenterology and motility

authors： Singh S,McCrary J,Kedar A,Weeks S,Beauerle B,Weeks A,Endashaw O,Lahr C,Starkebaum W,Abell T

更新日期：2015-10-01 00:00:00

abstract：Background/Aims:Probiotics are expected to modify the composition of gut microbiota. We aimed to investigate the changes in the composition and diversity of gut microbiota by the administration of probiotics in healthy individuals. Methods:Twelve healthy volunteers with age range of 30-42 years provided baseline fecal...

journal_title：Journal of neurogastroenterology and motility

authors： Noh CK,Kim BS,Hong G,Cheong JY,Lee KJ

更新日期：2018-07-30 00:00:00

abstract：BACKGROUND/AIMS:In isolated guinea-pig colon, we investigated regional differences in peristalsis evoked by intrinsic electrical nerve stimulation. METHODS:Four colonic segments from mid and distal colon of Hartley guinea pigs, were mounted horizontally in an organ bath. Measurement of pellet propulsion time, intralum...

journal_title：Journal of neurogastroenterology and motility

authors： Kwak JM,Babygirija R,Gribovskaja-Rupp I,Takahashi T,Yamato S,Ludwig K

更新日期：2013-04-01 00:00:00

abstract：:Irritable bowel syndrome (IBS) has been one of the commonly presented gastrointestinal disorders. It is of interest how commonly it presents in the society. Western studies indicated that most population-based IBS prevalences range 10%-15%. It is believed that IBS is prevalent in both East and West countries without a...

journal_title：Journal of neurogastroenterology and motility

authors： Chang FY,Lu CL,Chen TS

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND/AIMS:Antispasmodics including otilonium bromide (OB) are recommended to treat irritable bowel syndrome (IBS). However, reports about OB experience in Asia is sparse. The purpose of present study was to provide the efficacy of OB in treating Asian IBS patients. METHODS:Overall, 117 IBS patients meeting Rome ...

journal_title：Journal of neurogastroenterology and motility

authors： Chang FY,Lu CL,Luo JC,Chen TS,Chen MJ,Chang HJ

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND/AIMS:Transient lower esophageal sphincter relaxation (TLESR) is the main mechanism of gastroesophageal reflux disease (GERD). The aim of this study was to investigate the characteristics of transient lower esophageal sphincter movement in patients with or without gastroesophageal reflux by high-resolution ma...

journal_title：Journal of neurogastroenterology and motility

authors： Kim HI,Hong SJ,Han JP,Seo JY,Hwang KH,Maeng HJ,Lee TH,Lee JS

更新日期：2013-07-01 00:00:00

abstract：:In predisposed individuals with long standing gastroesophageal reflux disease (GERD), esophageal squamous mucosa can transform into columnar mucosa with intestinal metaplasia, commonly called Barrett's esophagus (BE). Barrett's mucosa can develop dysplasia, which can be a precursor for esophageal adenocarcinoma (EAC)....

journal_title：Journal of neurogastroenterology and motility

authors： Patel A,Gyawali CP

更新日期：2019-04-30 00:00:00

abstract：Background/Aims:Interstitial cells play important roles in gastrointestinal (GI) neuro-smooth muscle transmission. The underlying mechanisms of colonic dysmotility have not been well illustrated. We established a partial colon obstruction (PCO) mouse model to investigate the changes of interstitial cells and the correl...

journal_title：Journal of neurogastroenterology and motility

authors： Wang Q,Zang J,Huang X,Lu H,Xu W,Chen J

更新日期：2019-10-30 00:00:00

abstract：:An increase in intracellular Ca(2+) is the primary trigger of contraction of gastrointestinal (GI) smooth muscles. However, increasing the Ca(2+) sensitivity of the myofilaments by elevating myosin light chain phosphorylation also plays an essential role. Inhibiting myosin light chain phosphatase activity with protein...

journal_title：Journal of neurogastroenterology and motility

authors： Perrino BA

更新日期：2016-04-30 00:00:00

abstract：BACKGROUND/AIMS:Several motility disorders are associated with disruption of interstitial cells of Cajal (ICC), which provide important functions, such as pacemaker activity, mediation of neural inputs and responses to stretch in the gastrointestinal (GI) tract. Restoration of ICC networks may be therapeutic for GI mot...

journal_title：Journal of neurogastroenterology and motility

authors： McCann CJ,Hwang SJ,Hennig GW,Ward SM,Sanders KM

更新日期：2014-07-31 00:00:00

abstract：Background/Aims:Irritable bowel syndrome (IBS) is a common disease characterized by intestinal dysmotility, the mechanism of which remains elusive. We aim to determine whether the high-affinity choline transporter 1 (CHT1), a determinant of cholinergic signaling capacity, modulates intestinal motility associated with s...

journal_title：Journal of neurogastroenterology and motility

authors： Lin MJ,Yu BP

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND/AIMS:Gastrointestinal symptoms and hypothalamus-pituitary-adrenal (HPA) axis dysfunction are frequently observed in patients with major depression. The primary aim of the study was to investigate the relationship between HPA-axis function and self-perceived functional gastrointestinal symptoms in major depre...

journal_title：Journal of neurogastroenterology and motility

authors： Karling P,Wikgren M,Adolfsson R,Norrback KF

更新日期：2016-04-30 00:00:00

abstract：BACKGROUND/AIMS:Rats with a spontaneous null mutation in endothelin receptor type B or Ednrb (sl/sl; spotting lethal) lack enteric neurons in the distal bowel and usually die within the first week after birth. This early postnatal lethality limits their use for examining the potential of cell therapy to treat Hirschspr...

journal_title：Journal of neurogastroenterology and motility

authors： Stamp LA,Obermayr F,Pontell L,Young HM,Xie D,Croaker DH,Song ZM,Furness JB

更新日期：2015-10-01 00:00:00

abstract：:Author's name was mis-typed. The name "Oya B Sezer" in the original article should have been written as "Oya Balcı Sezer." ...

journal_title：Journal of neurogastroenterology and motility

authors： Sezer OB,Sezer T

更新日期：2019-01-31 00:00:00

abstract：:Assessment of transit through the gastrointestinal tract provides useful information regarding gut physiology and patho-physiology. Although several methods are available, each has distinct advantages and limitations. Recently, an ingestible wire-less motility capsule (WMC), similar to capsule video endoscopy, has bec...

journal_title：Journal of neurogastroenterology and motility

authors： Lee YY,Erdogan A,Rao SS

更新日期：2014-04-30 00:00:00

abstract：:That gastrointestinal motility can influence the gut microbiota has been known for decades and the clinical consequences of impaired motility, in terms of the bacterial population of the small intestine, amply illustrated by the syndrome of small intestinal bacterial overgrowth which so commonly accompanies diffuse in...

journal_title：Journal of neurogastroenterology and motility

authors： Quigley EM

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND/AIMS:Irritable bowel syndrome (IBS) is one of the most frequently observed disorders by primary care and practitioners. The aim of this study was to estimate the prevalence of IBS using the Rome II and III criteria in the general Korean population and also to compare sociodemographic differences between subj...

journal_title：Journal of neurogastroenterology and motility

authors： Park DW,Lee OY,Shim SG,Jun DW,Lee KN,Kim HY,Lee HL,Yoon BC,Choi HS

更新日期：2010-04-01 00:00:00

abstract：Background/Aims:Lipopolysaccharide (LPS) is the key factor inducing mucosal and systemic inflammation in various intestinal and parenteral diseases, which could initially disrupt the epithelial barrier function. EphrinA1/ephA2 is speculated to increase the epithelial permeability for its "repulsive interaction" between...

journal_title：Journal of neurogastroenterology and motility

authors： Chen Y,Zhang L,Zhang Y,Bai T,Song J,Qian W,Hou X

更新日期：2020-07-30 00:00:00

abstract：BACKGROUND/AIMS:Irritable bowel syndrome (IBS) is a widespread chronic health condition which is significantly more prevalent in women. We conducted a gender difference analysis by comparing findings of men and women to determine whether any significant differences exist or not. METHODS:This single-center study was co...

journal_title：Journal of neurogastroenterology and motility

authors： Anbardan SJ,Daryani NE,Fereshtehnejad SM,Taba Taba Vakili S,Keramati MR,Ajdarkosh H

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND/AIMS:Functional gastrointestinal disorders (FGIDs), diagnosed by symptom-based criteria due to lack of biomarkers, need translatedvalidated questionnaires in different languages. As Bengali, the mother tongue of Bangladesh and eastern India, is the seventh most spoken language in the world, we translated and...

journal_title：Journal of neurogastroenterology and motility

authors： Rahman MM,Ghoshal UC,Rowshon AH,Ahmed F,Kibria MG,Hasan M,Gwee KA,Whitehead WE

更新日期：2016-04-30 00:00:00

abstract：Background/Aims:Functional dyspepsia (FD) is characterized as chronic recurrent upper gastrointestinal symptoms in the absence of any organic disorder. We hypothesized that duodenal low-grade inflammation activates superficial afferent nerve sprouting, thereby contributing to hypersensitivity in patients with FD. Meth...

journal_title：Journal of neurogastroenterology and motility

authors： Lee MJ,Jung HK,Lee KE,Mun YC,Park S

更新日期：2019-04-30 00:00:00

abstract：Background/Aims:Integrated relaxation pressure (IRP) is defined as the average minimum esophagogastric junction (EGJ) pressure for 4 seconds of relaxation (contiguous or noncontiguous) within 10 seconds of swallowing. The durability of IRP values during successive swallows in the supine position remains to be elucidate...

journal_title：Journal of neurogastroenterology and motility

authors： Elangovan A,Shibli F,Fass R

更新日期：2021-01-28 00:00:00

abstract：Background/Aims:Current evidence suggests the presence of motility or functional abnormalities in one area of the gastrointestinal tract increases the likelihood of abnormalities in others. However, the relationship of gastroparesis to chronic constipation (slow transit constipation and dyssynergic defecation) has been...

journal_title：Journal of neurogastroenterology and motility

authors： Zikos TA,Kamal AN,Neshatian L,Triadafilopoulos G,Clarke JO,Nandwani M,Nguyen LA

更新日期：2019-04-30 00:00:00

abstract：:This article highlights the role of prucalopride in the management of chronic constipation based upon the principles of meta-analysis using data reported in the published randomized, controlled trials. Sixteen randomized, controlled trials on 3943 patients reported the effectiveness of prucalopride in patients with ch...

journal_title：Journal of neurogastroenterology and motility

authors： Sajid MS,Hebbar M,Baig MK,Li A,Philipose Z

更新日期：2016-07-30 00:00:00

abstract：BACKGROUND/AIMS:Interstitial cells of Cajal (ICC) play important functions in motor activity of the gastrointestinal tract. The role of ICC as pace-makers is well established, however their participation in neurotransmission is controversial. Studies using mutant animals that lack ICC have yielded variable conclusions ...

journal_title：Journal of neurogastroenterology and motility

authors： Sanders KM,Salter AK,Hennig GW,Koh SD,Perrino BA,Ward SM,Baker SA

更新日期：2014-04-30 00:00:00

abstract：BACKGROUND/AIMS:To evaluate the effects of the phosphodiesterase type 5 (PDE5) inhibitor vardenafil on esophageal function, including bolus transit, using multichannel intraluminal impedance and esophageal manometry (MII-EM). METHODS:Sixteen healthy volunteers (15 men) underwent an MII-EM study including 10 liquid swa...

journal_title：Journal of neurogastroenterology and motility

authors： Lee TH,Lee JS,Hong SJ,Jeon SR,Kim WJ,Kim HG,Cho JY,Kim JO

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND/AIMS:Proton pump inhibitors (PPIs) which are the most effective agents for the treatment of gastroesophageal reflux disease (GERD), have been known to delay gastric emptying. Mosapride has been used as prokinetics by accelerating gastric emptying. We evaluated the efficacy of mosapride to prevent PPI-induced...

journal_title：Journal of neurogastroenterology and motility

authors： Lim HC,Kim JH,Youn YH,Lee EH,Lee BK,Park H

更新日期：2013-10-01 00:00:00

abstract：Background/Aims:Currently, there exists no biomarker for visceral hypersensitivity in irritable bowel syndrome (IBS). Piezo proteins have been proven to play an important role in the mechanical stimulation to induce visceral pain in other tissues and may also be a biomarker candidate. The aim of this study was to test ...

journal_title：Journal of neurogastroenterology and motility

authors： Bai T,Li Y,Xia J,Jiang Y,Zhang L,Wang H,Qian W,Song J,Hou X

更新日期：2017-07-30 00:00:00

abstract：:Constipation in children is a common health problem affecting 0.7% to 29.6% children across the world. Exact etiology for developing symptoms is not clear in children and the majority is considered to have functional constipation. Alteration of rectal and pelvic floor function through the brain-gut axis seems to play ...

journal_title：Journal of neurogastroenterology and motility

authors： Rajindrajith S,Devanarayana NM

更新日期：2011-01-01 00:00:00

abstract：:Visceral pain is the most common form of pain caused by varied diseases and a major reason for patients to seek medical consultation. It also leads to a significant economic burden due to workdays lost and reduced productivity. Further, long-term use of non-specific medications is also associated with side effects aff...

journal_title：Journal of neurogastroenterology and motility

authors： Kannampalli P,Sengupta JN

更新日期：2015-03-30 00:00:00