Role of principal ionotropic and metabotropic receptors in visceral pain.

abstract：:Assessment of transit through the gastrointestinal tract provides useful information regarding gut physiology and patho-physiology. Although several methods are available, each has distinct advantages and limitations. Recently, an ingestible wire-less motility capsule (WMC), similar to capsule video endoscopy, has bec...

journal_title：Journal of neurogastroenterology and motility

authors： Lee YY,Erdogan A,Rao SS

更新日期：2014-04-30 00:00:00

abstract：:This article highlights the role of prucalopride in the management of chronic constipation based upon the principles of meta-analysis using data reported in the published randomized, controlled trials. Sixteen randomized, controlled trials on 3943 patients reported the effectiveness of prucalopride in patients with ch...

journal_title：Journal of neurogastroenterology and motility

authors： Sajid MS,Hebbar M,Baig MK,Li A,Philipose Z

更新日期：2016-07-30 00:00:00

abstract：:Cyclic vomiting syndrome (CVS) is a disorder characterized by recurrent episodes of incapacitating nausea and vomiting interspersed with symptom free periods. Common triggers of cyclic vomiting include noxious stress, excitement, fatigue and menstrual period. Here, we report a case of cyclic vomiting syndrome in adult...

journal_title：Journal of neurogastroenterology and motility

authors： Shin YK,Kwon JG,Kim KY,Park JB,Han SJ,Cheon JW,Kim EY,Kim HG,Lee TS,Park KS,Won KS

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND/AIMS:Gastroparesis-like syndrome (GLS) is defined as gastroparesis-like symptoms with normal gastric scintigraphy. While the efficacy of gastric electrical stimulation (GES) in gastroparesis is well known, the utility of GES in GLS is largely unknown. Our aim was to clarify the role of GES in GLS. We implant...

journal_title：Journal of neurogastroenterology and motility

authors： Singh S,McCrary J,Kedar A,Weeks S,Beauerle B,Weeks A,Endashaw O,Lahr C,Starkebaum W,Abell T

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND/AIMS:Antispasmodics including otilonium bromide (OB) are recommended to treat irritable bowel syndrome (IBS). However, reports about OB experience in Asia is sparse. The purpose of present study was to provide the efficacy of OB in treating Asian IBS patients. METHODS:Overall, 117 IBS patients meeting Rome ...

journal_title：Journal of neurogastroenterology and motility

authors： Chang FY,Lu CL,Luo JC,Chen TS,Chen MJ,Chang HJ

更新日期：2011-10-01 00:00:00

abstract：Background/Aims:The prevalence of eosinophilic esophagitis (EoE) is reportedly increasing in Western countries. However, its prevalence in Korea remains unknown. We investigated the diagnostic trends and clinical characteristics of EoE in Korea. Methods:Using an endoscopic database maintained at a tertiary care center...

journal_title：Journal of neurogastroenterology and motility

authors： Kim GH,Jung KW,Jung HY,Choi KD,Lee J,Park YS,Kim SW,Lee JH,Kim DH,Ahn JY,Song HJ,Lee GH,Kim JH

更新日期：2018-04-30 00:00:00

abstract：BACKGROUND/AIMS:To draw a normative database of laryngopharynx pH profile in Chinese subjects. METHODS:Normal volunteers were recruited from "www.Ganji.com" and People's hospital between May 2008 and December 2009. The Restech pH Probes were calibrated in pH 7 and pH 4 buffer solutions according to the manufacturer's ...

journal_title：Journal of neurogastroenterology and motility

authors： Feng G,Wang J,Zhang L,Liu Y

更新日期：2014-07-31 00:00:00

abstract：:Author's name was mis-typed. The name "Oya B Sezer" in the original article should have been written as "Oya Balcı Sezer." ...

journal_title：Journal of neurogastroenterology and motility

authors： Sezer OB,Sezer T

更新日期：2019-01-31 00:00:00

abstract：BACKGROUND/AIMS:Transient lower esophageal sphincter relaxation (TLESR) is the main mechanism of gastroesophageal reflux disease (GERD). The aim of this study was to investigate the characteristics of transient lower esophageal sphincter movement in patients with or without gastroesophageal reflux by high-resolution ma...

journal_title：Journal of neurogastroenterology and motility

authors： Kim HI,Hong SJ,Han JP,Seo JY,Hwang KH,Maeng HJ,Lee TH,Lee JS

更新日期：2013-07-01 00:00:00

abstract：Background/Aims:Since the use of dexlansoprazole in Asian subjects with gastroesophageal reflux disease (GERD) has not been adequately characterized, this study was conducted to evaluate the efficacy and safety of dexlansoprazole modified-release in Asian subjects with non-erosive reflux disease (NERD) and erosive esop...

journal_title：Journal of neurogastroenterology and motility

authors： Wu JCY,Sheu BS,Wu MS,Lee YC,Choi MG

更新日期：2020-01-30 00:00:00

abstract：Background/Aims:Current evidence suggests the presence of motility or functional abnormalities in one area of the gastrointestinal tract increases the likelihood of abnormalities in others. However, the relationship of gastroparesis to chronic constipation (slow transit constipation and dyssynergic defecation) has been...

journal_title：Journal of neurogastroenterology and motility

authors： Zikos TA,Kamal AN,Neshatian L,Triadafilopoulos G,Clarke JO,Nandwani M,Nguyen LA

更新日期：2019-04-30 00:00:00

abstract：BACKGROUND/AIMS:The marketing of newer agents for treatment of constipation and irritable bowel syndrome with constipation (IBS-C) emphasize improvements in abdominal pain. However, it is not clear whether this observation reflects a unique visceral analgesic effect of these agents or is a general feature of effective ...

journal_title：Journal of neurogastroenterology and motility

authors： Bielefeldt K,Levinthal DJ,Nusrat S

更新日期：2016-01-31 00:00:00

abstract：:Irritable bowel syndrome (IBS) has been one of the commonly presented gastrointestinal disorders. It is of interest how commonly it presents in the society. Western studies indicated that most population-based IBS prevalences range 10%-15%. It is believed that IBS is prevalent in both East and West countries without a...

journal_title：Journal of neurogastroenterology and motility

authors： Chang FY,Lu CL,Chen TS

更新日期：2010-10-01 00:00:00

abstract：Background/Aims:Currently, there exists no biomarker for visceral hypersensitivity in irritable bowel syndrome (IBS). Piezo proteins have been proven to play an important role in the mechanical stimulation to induce visceral pain in other tissues and may also be a biomarker candidate. The aim of this study was to test ...

journal_title：Journal of neurogastroenterology and motility

authors： Bai T,Li Y,Xia J,Jiang Y,Zhang L,Wang H,Qian W,Song J,Hou X

更新日期：2017-07-30 00:00:00

abstract：Background/Aims:Irritable bowel syndrome (IBS) is a common disease characterized by intestinal dysmotility, the mechanism of which remains elusive. We aim to determine whether the high-affinity choline transporter 1 (CHT1), a determinant of cholinergic signaling capacity, modulates intestinal motility associated with s...

journal_title：Journal of neurogastroenterology and motility

authors： Lin MJ,Yu BP

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND/AIMS:Recent studies reveal that acute gastroenteritis can precipitate irritable bowel syndrome (IBS) symptoms leading to the concept of post-infectious IBS. However, the overall contribution of gastroenteritis to the total IBS prevalence is unknown. In this exercise we try to estimate the contribution of gas...

journal_title：Journal of neurogastroenterology and motility

authors： Shah ED,Riddle MS,Chang C,Pimentel M

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND/AIMS:Rats with a spontaneous null mutation in endothelin receptor type B or Ednrb (sl/sl; spotting lethal) lack enteric neurons in the distal bowel and usually die within the first week after birth. This early postnatal lethality limits their use for examining the potential of cell therapy to treat Hirschspr...

journal_title：Journal of neurogastroenterology and motility

authors： Stamp LA,Obermayr F,Pontell L,Young HM,Xie D,Croaker DH,Song ZM,Furness JB

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND/AIMS:Approximately one-third of non-erosive reflux disease (NERD) patients are refractory to proton pump inhibitors (PPI) and face a therapeutic challenge. Therefore, it is important to differentiate between pathological and non-pathological reflux utilizing multichannel intraluminal impedance-pH (MII-pH) to...

journal_title：Journal of neurogastroenterology and motility

authors： Khan MQ,Alaraj A,Alsohaibani F,Al-Kahtani K,Jbarah S,Al-Ashgar H

更新日期：2014-10-30 00:00:00

abstract：Background/Aims:The Gastroesophageal Reflux Disease Questionnaire (GerdQ) has been developed and validated as a tool for the diagnosis of gastroesophageal reflux disease (GERD) in patients with gastrointestinal symptoms. However, the GerdQ and the cutoff value for determining GERD has not been validated in Korea. Meth...

journal_title：Journal of neurogastroenterology and motility

authors： Gong EJ,Jung KW,Min YW,Hong KS,Jung HK,Son HJ,Kim DY,Lee J,Lee OY

更新日期：2019-01-31 00:00:00

abstract：BACKGROUND/AIMS:Despite numerous studies on the relation of genetic polymorphisms with irritable bowel syndrome (IBS), the results still remain inconclusive. The aim of this study was to assess the possible association between SLC6A4 serotonin transporter gene linked polymorphic region (5-HTTLPR), ADRA2A -1291C>G, GNB3...

journal_title：Journal of neurogastroenterology and motility

authors： Choi YJ,Hwang SW,Kim N,Park JH,Oh JC,Lee DH

更新日期：2014-07-31 00:00:00

abstract：BACKGROUND/AIMS:Functional gastrointestinal disorders (FGIDs), diagnosed by symptom-based criteria due to lack of biomarkers, need translatedvalidated questionnaires in different languages. As Bengali, the mother tongue of Bangladesh and eastern India, is the seventh most spoken language in the world, we translated and...

journal_title：Journal of neurogastroenterology and motility

authors： Rahman MM,Ghoshal UC,Rowshon AH,Ahmed F,Kibria MG,Hasan M,Gwee KA,Whitehead WE

更新日期：2016-04-30 00:00:00

abstract：Background/Aims:Lipopolysaccharide (LPS) is the key factor inducing mucosal and systemic inflammation in various intestinal and parenteral diseases, which could initially disrupt the epithelial barrier function. EphrinA1/ephA2 is speculated to increase the epithelial permeability for its "repulsive interaction" between...

journal_title：Journal of neurogastroenterology and motility

authors： Chen Y,Zhang L,Zhang Y,Bai T,Song J,Qian W,Hou X

更新日期：2020-07-30 00:00:00

abstract：BACKGROUND/AIMS:In isolated guinea-pig colon, we investigated regional differences in peristalsis evoked by intrinsic electrical nerve stimulation. METHODS:Four colonic segments from mid and distal colon of Hartley guinea pigs, were mounted horizontally in an organ bath. Measurement of pellet propulsion time, intralum...

journal_title：Journal of neurogastroenterology and motility

authors： Kwak JM,Babygirija R,Gribovskaja-Rupp I,Takahashi T,Yamato S,Ludwig K

更新日期：2013-04-01 00:00:00

abstract：:An increase in intracellular Ca(2+) is the primary trigger of contraction of gastrointestinal (GI) smooth muscles. However, increasing the Ca(2+) sensitivity of the myofilaments by elevating myosin light chain phosphorylation also plays an essential role. Inhibiting myosin light chain phosphatase activity with protein...

journal_title：Journal of neurogastroenterology and motility

authors： Perrino BA

更新日期：2016-04-30 00:00:00

abstract：Background/Aims:Nausea, an unpleasant symptom of diabetic gastroparesis (DMGP), has been reported to be alleviated by needleless transcutaneous electrical acupuncture (TEA). Our study was designed to utilize electroencephalography (EEG) and electrogastrography (EGG) recordings to investigate the central and peripheral ...

journal_title：Journal of neurogastroenterology and motility

authors： Sarosiek I,Song G,Sun Y,Sandoval H,Sands S,Chen J,McCallum RW

更新日期：2017-04-30 00:00:00

abstract：:The mammalian intestine contains many different cell types but is comprised of 2 main cell types: epithelial cells and smooth muscle cells. Recent in vivo and in vitro evidence has revealed that various alterations to the DNA methylation apparatus within both of these cell types can result in a variety of cellular phe...

journal_title：Journal of neurogastroenterology and motility

authors： Jorgensen BG,Ro S

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND/AIMS:Irritable bowel syndrome (IBS) is one of the most frequently observed disorders by primary care and practitioners. The aim of this study was to estimate the prevalence of IBS using the Rome II and III criteria in the general Korean population and also to compare sociodemographic differences between subj...

journal_title：Journal of neurogastroenterology and motility

authors： Park DW,Lee OY,Shim SG,Jun DW,Lee KN,Kim HY,Lee HL,Yoon BC,Choi HS

更新日期：2010-04-01 00:00:00

abstract：Background/Aims:Interstitial cells play important roles in gastrointestinal (GI) neuro-smooth muscle transmission. The underlying mechanisms of colonic dysmotility have not been well illustrated. We established a partial colon obstruction (PCO) mouse model to investigate the changes of interstitial cells and the correl...

journal_title：Journal of neurogastroenterology and motility

authors： Wang Q,Zang J,Huang X,Lu H,Xu W,Chen J

更新日期：2019-10-30 00:00:00

abstract：:In predisposed individuals with long standing gastroesophageal reflux disease (GERD), esophageal squamous mucosa can transform into columnar mucosa with intestinal metaplasia, commonly called Barrett's esophagus (BE). Barrett's mucosa can develop dysplasia, which can be a precursor for esophageal adenocarcinoma (EAC)....

journal_title：Journal of neurogastroenterology and motility

authors： Patel A,Gyawali CP

更新日期：2019-04-30 00:00:00

abstract：BACKGROUND/AIMS:While it is well established that acupuncture relieves somatic pain, its therapeutic effect on visceral pain such as irritable bowel syndrome (IBS) is unclear. We evaluated the effect of acupuncture in treating visceral hyperalgesia in an animal model. METHODS:Sprague-Dawley rats (n = 8 per group) with...

journal_title：Journal of neurogastroenterology and motility

authors： Wu JC,Ziea ET,Lao L,Lam EF,Chan CS,Liang AY,Chu SL,Yew DT,Berman BM,Sung JJ

更新日期：2010-07-01 00:00:00