Abstract:
BACKGROUND/AIMS:Rome criteria classifying functional gastrointestinal disorder (FGID) were updated. The aims of this study were to assess the spectra of FGID and to evaluate the applicability of Rome III criteria in Korea. METHODS:New patients who visited 2 primary clinics and 2 tertiary care hospitals were consecutively invited to complete questionnaires. These consisted of questionnaires for FGID based on Rome III criteria and symptom checklist-90-revised for somatization, depression and anxiety. RESULTS:A total of 786 patients was participated. Among them, FGID was observed in 49.7%. In the patients with FGID, functional dyspepsia was most common (46.0%) followed by irritable bowel syndrome (IBS, 40.2%). Functional dyspepsia was most common both in the primary care clinics and tertiary care hospitals. Postprandial distress syndrome was the most common subtype and the frequency of epigastric pain syndrome was low. There were few responders for constipation as Bristol types 1 and 2 and for diarrhea as types 6 and 7 in subtype classification using the Bristol Stool Form Scale. Thereby, unspecified IBS defined by stool form was unexpectedly common in 43.9% of IBS, whereas unspedified IBS defined by Rome III definition was 5.1%. Patients with overlap FGIDs had higher score of anxiety, depression or somatization. CONCLUSIONS:FGIDs were common both in primary care clinics and tertiary care hospitals of Korea. Overlap FGIDs is still common by Rome III criteria, which may limits its wide application.
journal_name
J Neurogastroenterol Motiljournal_title
Journal of neurogastroenterology and motilityauthors
Park JM,Choi MG,Cho YK,Lee IS,Kim JI,Kim SW,Chung ISdoi
10.5056/jnm.2011.17.3.279subject
Has Abstractpub_date
2011-07-01 00:00:00pages
279-86issue
3eissn
2093-0879issn
2093-0887journal_volume
17pub_type
杂志文章abstract:BACKGROUND/AIMS:Recent studies reveal that acute gastroenteritis can precipitate irritable bowel syndrome (IBS) symptoms leading to the concept of post-infectious IBS. However, the overall contribution of gastroenteritis to the total IBS prevalence is unknown. In this exercise we try to estimate the contribution of gas...
journal_title:Journal of neurogastroenterology and motility
pub_type: 杂志文章
doi:10.5056/jnm.2012.18.2.200
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND/AIMS:Irritable bowel syndrome (IBS) is one of the most frequently observed disorders by primary care and practitioners. The aim of this study was to estimate the prevalence of IBS using the Rome II and III criteria in the general Korean population and also to compare sociodemographic differences between subj...
journal_title:Journal of neurogastroenterology and motility
pub_type: 杂志文章
doi:10.5056/jnm.2010.16.2.186
更新日期:2010-04-01 00:00:00
abstract:Background/Aims:Irritable bowel syndrome (IBS) is a common disease characterized by intestinal dysmotility, the mechanism of which remains elusive. We aim to determine whether the high-affinity choline transporter 1 (CHT1), a determinant of cholinergic signaling capacity, modulates intestinal motility associated with s...
journal_title:Journal of neurogastroenterology and motility
pub_type: 杂志文章
doi:10.5056/jnm18040
更新日期:2018-10-01 00:00:00
abstract:Background/Aims:Integrated relaxation pressure (IRP) is defined as the average minimum esophagogastric junction (EGJ) pressure for 4 seconds of relaxation (contiguous or noncontiguous) within 10 seconds of swallowing. The durability of IRP values during successive swallows in the supine position remains to be elucidate...
journal_title:Journal of neurogastroenterology and motility
pub_type: 杂志文章
doi:10.5056/jnm20139
更新日期:2021-01-28 00:00:00
abstract:Background/Aims:Recent studies suggest that air pollution may play a role in gastrointestinal disorders. However, the effect of long-term exposure to air pollution on childhood irritable bowel syndrome (IBS) is unclear. Hence, we conducted a nationwide cohort study to investigate the association between long-term air p...
journal_title:Journal of neurogastroenterology and motility
pub_type: 杂志文章
doi:10.5056/jnm18135
更新日期:2019-04-30 00:00:00
abstract:BACKGROUND/AIMS:Irritable bowel syndrome (IBS) is a widespread chronic health condition which is significantly more prevalent in women. We conducted a gender difference analysis by comparing findings of men and women to determine whether any significant differences exist or not. METHODS:This single-center study was co...
journal_title:Journal of neurogastroenterology and motility
pub_type: 杂志文章
doi:10.5056/jnm.2012.18.1.70
更新日期:2012-01-01 00:00:00
abstract:Background/Aims:The prevalence of eosinophilic esophagitis (EoE) is reportedly increasing in Western countries. However, its prevalence in Korea remains unknown. We investigated the diagnostic trends and clinical characteristics of EoE in Korea. Methods:Using an endoscopic database maintained at a tertiary care center...
journal_title:Journal of neurogastroenterology and motility
pub_type: 杂志文章
doi:10.5056/jnm17047
更新日期:2018-04-30 00:00:00
abstract:Background/Aims:Interstitial cells play important roles in gastrointestinal (GI) neuro-smooth muscle transmission. The underlying mechanisms of colonic dysmotility have not been well illustrated. We established a partial colon obstruction (PCO) mouse model to investigate the changes of interstitial cells and the correl...
journal_title:Journal of neurogastroenterology and motility
pub_type: 杂志文章
doi:10.5056/jnm19136
更新日期:2019-10-30 00:00:00
abstract:BACKGROUND/AIMS:Rats with a spontaneous null mutation in endothelin receptor type B or Ednrb (sl/sl; spotting lethal) lack enteric neurons in the distal bowel and usually die within the first week after birth. This early postnatal lethality limits their use for examining the potential of cell therapy to treat Hirschspr...
journal_title:Journal of neurogastroenterology and motility
pub_type: 杂志文章
doi:10.5056/jnm15079
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND/AIMS:Approximately one-third of non-erosive reflux disease (NERD) patients are refractory to proton pump inhibitors (PPI) and face a therapeutic challenge. Therefore, it is important to differentiate between pathological and non-pathological reflux utilizing multichannel intraluminal impedance-pH (MII-pH) to...
journal_title:Journal of neurogastroenterology and motility
pub_type: 杂志文章
doi:10.5056/jnm14038
更新日期:2014-10-30 00:00:00
abstract::Gastroesophageal reflux disease (GERD) is a very common disease, and the prevalence in the general population has recently increased. GERD is a chronic relapsing disease associated with motility disorders of the upper gastrointestinal tract. Several factors are implicated in GERD, including hypotensive lower esophagea...
journal_title:Journal of neurogastroenterology and motility
pub_type: 评审
doi:10.5056/jnm19081
更新日期:2019-10-30 00:00:00
abstract:BACKGROUND/AIMS:Several motility disorders are associated with disruption of interstitial cells of Cajal (ICC), which provide important functions, such as pacemaker activity, mediation of neural inputs and responses to stretch in the gastrointestinal (GI) tract. Restoration of ICC networks may be therapeutic for GI mot...
journal_title:Journal of neurogastroenterology and motility
pub_type: 杂志文章
doi:10.5056/jnm14026
更新日期:2014-07-31 00:00:00
abstract:Background/Aims:Since the use of dexlansoprazole in Asian subjects with gastroesophageal reflux disease (GERD) has not been adequately characterized, this study was conducted to evaluate the efficacy and safety of dexlansoprazole modified-release in Asian subjects with non-erosive reflux disease (NERD) and erosive esop...
journal_title:Journal of neurogastroenterology and motility
pub_type: 杂志文章
doi:10.5056/jnm19031
更新日期:2020-01-30 00:00:00
abstract::An increase in intracellular Ca(2+) is the primary trigger of contraction of gastrointestinal (GI) smooth muscles. However, increasing the Ca(2+) sensitivity of the myofilaments by elevating myosin light chain phosphorylation also plays an essential role. Inhibiting myosin light chain phosphatase activity with protein...
journal_title:Journal of neurogastroenterology and motility
pub_type: 杂志文章,评审
doi:10.5056/jnm15186
更新日期:2016-04-30 00:00:00
abstract::Irritable bowel syndrome (IBS) has been one of the commonly presented gastrointestinal disorders. It is of interest how commonly it presents in the society. Western studies indicated that most population-based IBS prevalences range 10%-15%. It is believed that IBS is prevalent in both East and West countries without a...
journal_title:Journal of neurogastroenterology and motility
pub_type: 杂志文章
doi:10.5056/jnm.2010.16.4.389
更新日期:2010-10-01 00:00:00
abstract:Background/Aims:The Gastroesophageal Reflux Disease Questionnaire (GerdQ) has been developed and validated as a tool for the diagnosis of gastroesophageal reflux disease (GERD) in patients with gastrointestinal symptoms. However, the GerdQ and the cutoff value for determining GERD has not been validated in Korea. Meth...
journal_title:Journal of neurogastroenterology and motility
pub_type: 杂志文章
doi:10.5056/jnm18133
更新日期:2019-01-31 00:00:00
abstract::Assessment of transit through the gastrointestinal tract provides useful information regarding gut physiology and patho-physiology. Although several methods are available, each has distinct advantages and limitations. Recently, an ingestible wire-less motility capsule (WMC), similar to capsule video endoscopy, has bec...
journal_title:Journal of neurogastroenterology and motility
pub_type: 杂志文章
doi:10.5056/jnm.2014.20.2.265
更新日期:2014-04-30 00:00:00
abstract::Author's name was mis-typed. The name "Oya B Sezer" in the original article should have been written as "Oya Balcı Sezer." ...
journal_title:Journal of neurogastroenterology and motility
pub_type: 已发布勘误
doi:10.5056/jnm25012
更新日期:2019-01-31 00:00:00
abstract:BACKGROUND/AIMS:Transient lower esophageal sphincter relaxation (TLESR) is the main mechanism of gastroesophageal reflux disease (GERD). The aim of this study was to investigate the characteristics of transient lower esophageal sphincter movement in patients with or without gastroesophageal reflux by high-resolution ma...
journal_title:Journal of neurogastroenterology and motility
pub_type: 杂志文章
doi:10.5056/jnm.2013.19.3.332
更新日期:2013-07-01 00:00:00
abstract:Background/Aims:Nausea, an unpleasant symptom of diabetic gastroparesis (DMGP), has been reported to be alleviated by needleless transcutaneous electrical acupuncture (TEA). Our study was designed to utilize electroencephalography (EEG) and electrogastrography (EGG) recordings to investigate the central and peripheral ...
journal_title:Journal of neurogastroenterology and motility
pub_type: 杂志文章
doi:10.5056/jnm16097
更新日期:2017-04-30 00:00:00
abstract:Background/Aims:Current evidence suggests the presence of motility or functional abnormalities in one area of the gastrointestinal tract increases the likelihood of abnormalities in others. However, the relationship of gastroparesis to chronic constipation (slow transit constipation and dyssynergic defecation) has been...
journal_title:Journal of neurogastroenterology and motility
pub_type: 杂志文章
doi:10.5056/jnm18206
更新日期:2019-04-30 00:00:00
abstract:BACKGROUND/AIMS:Functional gastrointestinal disorders (FGIDs), diagnosed by symptom-based criteria due to lack of biomarkers, need translatedvalidated questionnaires in different languages. As Bengali, the mother tongue of Bangladesh and eastern India, is the seventh most spoken language in the world, we translated and...
journal_title:Journal of neurogastroenterology and motility
pub_type: 杂志文章
doi:10.5056/jnm15129
更新日期:2016-04-30 00:00:00
abstract:Background/Aims:Currently, there exists no biomarker for visceral hypersensitivity in irritable bowel syndrome (IBS). Piezo proteins have been proven to play an important role in the mechanical stimulation to induce visceral pain in other tissues and may also be a biomarker candidate. The aim of this study was to test ...
journal_title:Journal of neurogastroenterology and motility
pub_type: 杂志文章
doi:10.5056/jnm16114
更新日期:2017-07-30 00:00:00
abstract:Background/Aims:Nutrient-induced gut hormone release (eg, cholecystokinin [CCK]) and the modulation of gut motility (particularly pyloric stimulation) contribute to the regulation of acute energy intake. Non-caloric bitter compounds, including quinine, have recently been shown in cell-line and animal studies to stimula...
journal_title:Journal of neurogastroenterology and motility
pub_type: 杂志文章
doi:10.5056/jnm19036
更新日期:2019-07-01 00:00:00
abstract:Background/Aims:High-resolution manometry (HRM) has broadened the awareness of minor esophageal peristaltic disorders. However, the treatments for these minor disorders are limited and the role of prokinetics has been controversial. This study evaluates the effect of mosapride in patients with minor peristaltic disorde...
journal_title:Journal of neurogastroenterology and motility
pub_type: 杂志文章
doi:10.5056/jnm19062
更新日期:2020-04-30 00:00:00
abstract:BACKGROUND/AIMS:While it is well established that acupuncture relieves somatic pain, its therapeutic effect on visceral pain such as irritable bowel syndrome (IBS) is unclear. We evaluated the effect of acupuncture in treating visceral hyperalgesia in an animal model. METHODS:Sprague-Dawley rats (n = 8 per group) with...
journal_title:Journal of neurogastroenterology and motility
pub_type: 杂志文章
doi:10.5056/jnm.2010.16.3.306
更新日期:2010-07-01 00:00:00
abstract:BACKGROUND/AIMS:Antispasmodics including otilonium bromide (OB) are recommended to treat irritable bowel syndrome (IBS). However, reports about OB experience in Asia is sparse. The purpose of present study was to provide the efficacy of OB in treating Asian IBS patients. METHODS:Overall, 117 IBS patients meeting Rome ...
journal_title:Journal of neurogastroenterology and motility
pub_type: 杂志文章
doi:10.5056/jnm.2011.17.4.402
更新日期:2011-10-01 00:00:00
abstract::Cyclic vomiting syndrome (CVS) is a disorder characterized by recurrent episodes of incapacitating nausea and vomiting interspersed with symptom free periods. Common triggers of cyclic vomiting include noxious stress, excitement, fatigue and menstrual period. Here, we report a case of cyclic vomiting syndrome in adult...
journal_title:Journal of neurogastroenterology and motility
pub_type: 杂志文章
doi:10.5056/jnm.2010.16.1.77
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND/AIMS:To evaluate the effects of the phosphodiesterase type 5 (PDE5) inhibitor vardenafil on esophageal function, including bolus transit, using multichannel intraluminal impedance and esophageal manometry (MII-EM). METHODS:Sixteen healthy volunteers (15 men) underwent an MII-EM study including 10 liquid swa...
journal_title:Journal of neurogastroenterology and motility
pub_type: 杂志文章
doi:10.5056/jnm.2012.18.4.399
更新日期:2012-10-01 00:00:00
abstract::This article highlights the role of prucalopride in the management of chronic constipation based upon the principles of meta-analysis using data reported in the published randomized, controlled trials. Sixteen randomized, controlled trials on 3943 patients reported the effectiveness of prucalopride in patients with ch...
journal_title:Journal of neurogastroenterology and motility
pub_type: meta分析
doi:10.5056/jnm16004
更新日期:2016-07-30 00:00:00