Determination of clenbuterol residues in retinal tissue of food-producing pigs.

abstract：:This article reports the impact of diuresis on urinary excretion of ethanol in seven healthy volunteers who drank 1000 mL of export beer (44 g ethanol) in 30 min and, 120 min later, ingested 500 or 1000 mL of water within 5 min. Urine was voided before drinking started and every 30-60 min for 360 min after the start o...

journal_title：Journal of analytical toxicology

authors： Bendtsen P,Jones AW

更新日期：1999-11-01 00:00:00

abstract：:The nitrogen mustards bis(2-chloroethyl)ethylamine (HN1), bis(2-chloroethyl)methylamine (HN2), and tris(2-chloroethyl)amine (HN3) have the potential to be used as chemical terrorism agents because of their extreme vesicant properties. We modified a previously reported method to incorporate automated solid-phase extrac...

journal_title：Journal of analytical toxicology

authors： Lemire SW,Barr JR,Ashley DL,Olson CT,Hayes TL

更新日期：2004-07-01 00:00:00

abstract：:As a part of ongoing testing of personnel preparing training aids for drug detection dogs at the Naval Criminal Investigative Service Regional Forensic Laboratory, personnel handling methamphetamine (MTH) were subject to voluntary urine drug testing. This provided a model of potential unwitting or environmental exposu...

journal_title：Journal of analytical toxicology

authors： Stout PR,Horn CK,Klette KL,Given J

更新日期：2006-10-01 00:00:00

abstract：:The misuse of the commonly used chemical diethylene glycol (DEG) has lead to many poisonings worldwide. Methods were developed for analysis of DEG and its potential metabolites; ethylene glycol, glycolic acid, oxalic acid, diglycolic acid and hydroxyethoxy acetic acid in human urine, serum and cerebrospinal fluid samp...

journal_title：Journal of analytical toxicology

authors： Perala AW,Filary MJ,Bartels MJ,McMartin KE

更新日期：2014-05-01 00:00:00

abstract：:A rapid, specific and quantitative high-performance liquid chromatography assay procedure is described for the determination of ICI 125, 211, (I), a guanidino-thiazole H2-receptor antagonist, in small samples of animal plasma. A 0.2 mL aliquot of plasma is extracted at pH 9 with ethyl acetate. After reconstitution in ...

journal_title：Journal of analytical toxicology

authors： Monson K,Simon RK,Malbica JO

更新日期：1980-09-01 00:00:00

abstract：:Dried blood spots (DBS) on filter paper have been used in human medicine since the 1960s, predominantly for screening in-borne metabolic disorders and more recently, for toxicology. Despite its 50-year existence, this technology has not been adopted by veterinarians for routine diagnoses and research. We have validate...

journal_title：Journal of analytical toxicology

authors： Lehner AF,Rumbeiha W,Shlosberg A,Stuart K,Johnson M,Domenech R,Langner H

更新日期：2013-09-01 00:00:00

abstract：:A 59-year-old white male accidentally ingested a mouthful of a plant growth chemical, Cycocel, containing 11.8% of the active ingredient (2-chloroethyl)trimethylammonium chloride (chlormequat). He was seen by a family physician and then transferred to a hospital where he died as a result of ventricular fibrillation, w...

journal_title：Journal of analytical toxicology

authors： Winek CL,Wahba WW,Edelstein JM

更新日期：1990-07-01 00:00:00

abstract：:Heart blood free oxycodone concentrations in oxycodone-related and mixed drug overdose deaths were compared with those found incidentally at autopsy in medical examiner cases. Between 2000 and 2005, 67 oxycodone-positive postmortem cases were identified. Thirty of 67 cases (44.8%) were determined to be drug overdoses....

journal_title：Journal of analytical toxicology

authors： Thompson JG,Vanderwerf S,Seningen J,Carr M,Kloss J,Apple FS

更新日期：2008-10-01 00:00:00

abstract：:A method that measures 12 analytes in urine and reflects possible exposure to pesticides was developed. The sample preparation involves enzyme hydrolysis and solvent extraction through the use of laboratory robotics, followed by phase-transfer catalysis derivatization and silica cleanup. Samples are analyzed by capill...

journal_title：Journal of analytical toxicology

authors： Hill RH Jr,Shealy DB,Head SL,Williams CC,Bailey SL,Gregg M,Baker SE,Needham LL

更新日期：1995-09-01 00:00:00

abstract：:A microextraction by packed sorbent (MEPS) procedure for rapid concentration of methadone and its primary metabolite (EDDP) in hair samples was developed. The miniaturized approach coupled to gas chromatography with tandem mass spectrometry (GC-MS-MS) was successfully validated. Hair samples (50 mg) were incubated wit...

journal_title：Journal of analytical toxicology

authors： Rosado T,Gallardo E,Vieira DN,Barroso M

更新日期：2020-12-12 00:00:00

abstract：:A method is presented for the extraction and screening of basic and neutral drugs, including amphetamines. Two milliliters of blood are buffered to pH 9.0 and extracted with n-chlorobutane. Underivatized extracts are analyzed simultaneously on two complementary capillary columns placed together in one injection port u...

journal_title：Journal of analytical toxicology

authors： Watts VW,Simonick TF

更新日期：1986-09-01 00:00:00

abstract：:A preliminary investigation was undertaken to determine the feasibility of monitoring saliva levels of drugs for forensic purposes. Single oral doses of the title compounds were administered to healthy volunteers. Plasma and saliva levels were measured and ratios calculated for all drugs except diazepam. Saliva/plasma...

journal_title：Journal of analytical toxicology

authors： Sharp ME,Wallace SM,Hindmarsh KW,Peel HW

更新日期：1983-01-01 00:00:00

abstract：:Analytical methods were developed to determine the presence of ethylenediaminetetraacetic acid (EDTA) in dried bloodstains to provide probative information when allegations of evidence tampering have been made in criminal cases. A simple screening method using ion chromatography to analyze stains was found to be quant...

journal_title：Journal of analytical toxicology

authors： Miller ML,McCord BR,Martz R,Budowle B

更新日期：1997-11-01 00:00:00

abstract：:Calibration model selection is required for all quantitative methods in toxicology and more broadly in bioanalysis. This typically involves selecting the equation order (quadratic or linear) and weighting factor correctly modelizing the data. A mis-selection of the calibration model will generate lower quality control...

journal_title：Journal of analytical toxicology

authors： Desharnais B,Camirand-Lemyre F,Mireault P,Skinner CD

更新日期：2017-05-01 00:00:00

abstract：:A high-performance liquid chromatographic method was used for the detection of etodolac in equine serum and urine. The method consisted of a one-step liquid-liquid extraction, separation on a reversed-phase (RP-18) column and detection using an ultraviolet detector. Additional confirmation methods included a HPLC coup...

journal_title：Journal of analytical toxicology

authors： Koupai-Abyazani MR,Esaw B,Laviolette B

更新日期：1999-05-01 00:00:00

abstract：:During periodate degradation of interfering ephedrine, pseudoephedrine, and phenylpropanolamine in the extraction of methamphetamine from urine, it was observed that a small amount of methamphetamine was demethylated to amphetamine. although all three interfering phenylpropanolamines could be degraded by periodate at ...

journal_title：Journal of analytical toxicology

authors： Paul BD,Past MR,McKinley RM,Foreman JD,McWhorter LK,Snyder JJ

更新日期：1994-10-01 00:00:00

abstract：:A liquid chromatographic-mass spectrometric assay with atmospheric pressure chemical ionization is presented for quantification (selected-ion mode) of tramadol (T) and O-desmethyltramadol (ODT) in blood plasma after liquid-liquid extraction. The enantiomeric separation was achieved on a Chiralpak AD column containing ...

journal_title：Journal of analytical toxicology

authors： Musshoff F,Madea B,Stuber F,Stamer UM

更新日期：2006-09-01 00:00:00

abstract：:Amoxapine, a tricyclic antidepressant, is metabolized to 8-hydroxyamoxapine and 7-hydroxyamoxapine. There are few reports on the metabolism of this drug and correlation of clinical symptoms in overdose patients. Five such patients admitted to the Emergency Unit of the University of Cincinnati Hospital were studied. Cl...

journal_title：Journal of analytical toxicology

authors： Tasset JJ,Pesce AJ

更新日期：1984-05-01 00:00:00

abstract：:Bone was analyzed for ketamine and norketamine to examine whether different patterns of drug exposure could be discriminated. Rats received (intraperitoneally) one 75 mg/kg dose (Acute-1 and Acute-2 groups), three 25-mg/kg doses 1 hour apart (Repeated group), or nine single daily ketamine doses of 75 mg/kg followed by...

journal_title：Journal of analytical toxicology

authors： Watterson JH,Donohue JP,Betit CC

更新日期：2012-07-01 00:00:00

abstract：:A 69-year-old male radio technician drank an unknown amount of a liquid and died within 5 h at a hospital. Mainly silver, potassium, and calcium, among other substances, were found in the residue of the liquid from the empty bottle by means of the spectrographic method (30.7% silver and 25.5% potassium using atomic ab...

journal_title：Journal of analytical toxicology

authors： Lech T

更新日期：1997-11-01 00:00:00

abstract：:A sensitive and robust ultra-high-performance liquid chromatography-tandem mass spectrometry method has been developed and validated for the quantification of acetaminophen, dexchlorpheniramine, caffeine, cotinine and salicylic acid in postmortem blood samples from children younger than 4 years. The sample was prepare...

journal_title：Journal of analytical toxicology

authors： Krpo M,Arnestad M,Karinen R

更新日期：2018-03-01 00:00:00

abstract：:A comparison was made of several cannabinoid urine assays. Two hundred randomly selected urine specimens were initially screened by two enzyme immunoassays (EMIT-st and EMIT-d.a.u.) and a radioimmunoassay (Abuscreen RIA). Selected specimens found positive by any of these methods were further analyzed by gas-liquid chr...

journal_title：Journal of analytical toxicology

authors： Irving J,Leeb B,Foltz RL,Cook CE,Bursey JT,Willette RE

更新日期：1984-07-01 00:00:00

abstract：:An original high-performance liquid chromatographic-mass spectrometric (HPLC-MS) procedure was developed for the determination of cyanide (CN) in whole blood. After the addition of K13C15N as internal standard, blood was placed in a microdiffusion device, the inner well of which was filled with a mixture of taurine (5...

journal_title：Journal of analytical toxicology

authors： Tracqui A,Raul JS,Géraut A,Berthelon L,Ludes B

更新日期：2002-04-01 00:00:00

abstract：:Suvorexant (Belsomra®) is a novel dual orexin receptor antagonist used for the treatment of insomnia. The prevalence of suvorexant in forensic samples is relatively unknown, which demonstrates the need for robust analytical assays for the detection of this sedative hypnotic in forensic toxicology laboratories. In this...

journal_title：Journal of analytical toxicology

authors： Skillman B,Kerrigan S

更新日期：2020-04-30 00:00:00

abstract：:A rapid and sensitive assay for pyridinium oximes in plasma and tissue was developed. The method was suitable for the analysis of mono- and di-pyridinium oximes and utilizes ultrafiltration followed by cation-exchange high-performance liquid chromatography with UV detection. The assay was originally developed for the ...

journal_title：Journal of analytical toxicology

authors： Singh H,Moorad-Doctor D,Ratcliffe RH,Wachtel K,Castillo A,Garcia GE

更新日期：2007-03-01 00:00:00

abstract：:Acetaminophen (APAP, n-acetyl-p-aminophenol) and salicylate (ASA, acetylsalicylic acid) are two of the most frequently overdosed drugs reported in the emergency room. Most APAP and ASA tests are performed with analytical instruments in laboratories, which are not always ideal for emergency situations. A rapid membrane...

journal_title：Journal of analytical toxicology

authors： Song W,Dou C

更新日期：2003-09-01 00:00:00

abstract：:The maximum stability conditions for cocaine and its metabolite benzoylecgonine (BE) in urine were analyzed. Suggestions were presented after careful review of many studies and personal communications concerning cocaine and BE stability in urine. The optimal storage conditions for urine specimens with cocaine and BE w...

journal_title：Journal of analytical toxicology

authors： Hippenstiel MJ,Gerson B

更新日期：1994-03-01 00:00:00

abstract：:We devised a highly sensitive method for simultaneously determining methamphetamine (MA) and amphetamine (AP) enantiomers, desmethylselegiline (DMSG) and selegiline (SG), in human hair using a derivatization technique and high-performance liquid chromatography-electrospray ionization-mass spectrometry (HPLC-ESI-MS). M...

journal_title：Journal of analytical toxicology

authors： Nishida K,Itoh S,Inoue N,Kudo K,Ikeda N

更新日期：2006-05-01 00:00:00

abstract：:We report a case involving unusually high postmortem morphine concentrations in a 44-year-old male with end-stage pancreatic cancer. He was receiving morphine for pain control via a single subclavian intravenous catheter. Allegations of foul play were made by family members at the time of death, so a full autopsy was ...

journal_title：Journal of analytical toxicology

authors： Kerrigan S,Honey D,Baker G

更新日期：2004-09-01 00:00:00

abstract：:Exposure to drugs and toxins is a major cause for the rising number of emergency department visits each year. Immunoassays are commonly used in the emergency department to provide rapid turnaround time for acute care. The purpose of this study was to compare two automated immunoassay chemistry analyzers to determine w...

journal_title：Journal of analytical toxicology

authors： Johnson-Davis KL,Thompson CD,Clark CJ,McMillin GA,Lehman CM

更新日期：2012-06-01 00:00:00