Abstract:
:Small noncoding RNAs are key controllers of cellular function, and their deregulation can lead to cancer development and metastatic evolution. This review summarizes the most important examples of small RNAs involved in human cancer and discusses their clinical use as biomarkers and drug targets for diagnosis, prognosis, and treatment of cancer. We also describe the possible mechanisms underlying small RNA-mediated transformation and outline the future describing new small RNA families with great potential in cancer biology.
journal_name
IUBMB Lifejournal_title
IUBMB lifeauthors
Rovira C,Güida MC,Cayota Adoi
10.1002/iub.399subject
Has Abstractpub_date
2010-12-01 00:00:00pages
859-68issue
12eissn
1521-6543issn
1521-6551journal_volume
62pub_type
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