Macromolecular mimicry of nucleic acid and protein.

Abstract:

:Although proteins and nucleic acids consist of different chemical components, proteins can mimic structures and possibly also functions of nucleic acids. Recently, structural mimicry was observed between two elongation factors in bacterial protein biosynthesis leading to the introduction of the concept of macromolecular mimicry. Macromolecular mimicry has further been proposed among initiation and release factors, thereby adding a new element to the description of protein synthesis in bacteria. Such mimicry has also been observed in other biological processes such as autoimmunity, DNA repair, and gene regulation, at both transcriptional and translational levels.

journal_name

IUBMB Life

journal_title

IUBMB life

authors

Pedersen GN,Nyborg J,Clark BF

doi

10.1080/713803471

keywords:

subject

Has Abstract

pub_date

1999-07-01 00:00:00

pages

13-8

issue

1

eissn

1521-6543

issn

1521-6551

journal_volume

48

pub_type

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