Abstract：
:Negative-pressure wound therapy (NPWT) is used to promote wound healing by using suction to drain excess fluid from wounds. A systematic literature review was undertaken to assess the effectiveness, safety and cost-effectiveness of NPWT for the treatment of chronic wounds. Medline, Embase, CENTRAL, CINAHL and the Cochrane Wounds Group Specialised Trials Register were searched. A total of 9 randomized controlled trials (n=568) comparing NPWT with conventional wound therapy and four economic evaluations identified through NHS EED database were included. Five trials showed significant differences in favour of NPWT in primary outcome measures; however, most studies had small sample sizes and low scientific validity. Complications and adverse effects of NPWT are scarce compared to those of conventional treatment. There is no conclusive scientific evidence on the effectiveness and cost-effectiveness of NPWT in the treatment of chronic wounds and therefore its widespread use is not justified.
journal_name
Med Clin (Barc)journal_title
Medicina clinicaauthors
Trujillo-Martín M,García-Pérez L,Serrano-Aguilar Pdoi
10.1016/j.medcli.2010.06.010subject
Has Abstractpub_date
2011-09-17 00:00:00pages
321-8issue
7eissn
0025-7753issn
1578-8989pii
S0025-7753(10)00743-8journal_volume
137pub_type
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