Abstract：
BACKGROUND:The identification of high risk groups for genital human papillomavirus (HPV) infection may contribute to cervical cancer prevention. The study was designed to estimate the prevalence of HPV infection and the related risk of cervical cancer among imprisoned women. PATIENTS AND METHODS:157 women were visited at the Medical Office of a prison in Barcelona, Spain. Women underwent a structured interview, determination of HIV serostatus and detection of HPV cervical infection by means of PCR. RESULTS:The prevalence of HPV infection was 46%. Prostitution was reported by 38.2% and intravenous drug use by 64.3%. HIV infection was detected in 56.1%. Cervical cytology revealed 19 women with ASCUS and 28 with squamous intraepithelial lesions (SIL) (all grades). HPV infection was associated with an increased risk of intravenous drug use for more than 10 years (prevalence odds ratio [POR] = 2.9) and seropositivity to HIV (POR = 4.7). The increase in risk for SIL related to HIV was explained by the presence of HPV. HIV positive women with low CD4 counts may increase the risk for SIL independently of HPV. CONCLUSION:HIV positive women are at high risk for HPV infection and as a consequence, for developing SIL. HIV positive women should be closely monitored for cervical cancer.
journal_name
Med Clin (Barc)journal_title
Medicina clinicaauthors
de Sanjosé S,Valls I,Paz Cañadas M,Lloveras B,Quintana MJ,Shah KV,Bosch FXdoi
10.1016/s0025-7753(00)71472-2keywords:
subject
Has Abstractpub_date
2000-06-17 00:00:00pages
81-4issue
3eissn
0025-7753issn
1578-8989pii
S0025-7753(00)71472-2journal_volume
115pub_type
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