Abstract：
BACKGROUND AND OBJECTIVE:Our goal was to determine the incidence of infection due to Mycobacterium kansasii in Elche, Spain over the last 10 years and to study the activity of new antibiotics against the strains isolated. MATERIAL AND METHODS:A retrospective study of patients and study of antibiotic susceptibility in vitro. RESULTS:The annual incidence of infection by this microorganism was 2.66 cases/ 1,000,000 inhabitants per year. In patients with AIDS, the incidence increased to 571.4 cases/1,000,000 inhabitants per year. Gatifloxacin and moxifloxacin exhibit better in vitro activity than levofloxacin; in some strains, a synergism exists between rifampi cin/fluoroquinolones and rifampicin/linezolid. CONCLUSION:In Elche, infections due to M. kansasii are uncommon. It is necesary to continue evaluating the activity of fluoroquinolones and linezolid.
journal_name
Med Clin (Barc)journal_title
Medicina clinicaauthors
Rodríguez JC,Ayelo A,Ruiz M,López M,Royo Gkeywords:
subject
Has Abstractpub_date
2003-03-01 00:00:00pages
253-4issue
7eissn
0025-7753issn
1578-8989pii
S0025-7753(03)73669-0journal_volume
120pub_type
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