[Guidelines for the prevention and control of tuberculosis in health care workers].


:Tuberculosis remains one of the communicable diseases that cause increased morbidity and mortality worldwide. With an incidence rate of 13,04 per 100,000 population, Spain ranks third among the most affected European countries. These data show a tendency to decrease meaning that it may go unnoticed with the potential to miss the appropriate preventive measures in a suspected case. In centers where patients are treated with tuberculosis, health care worker presents risk of transmission. This risk is higher in some areas or work units. The Occupational health physicians' services, which monitorize the health of health care workers, use different strategies in order to prevent and detect tuberculosis infection. The national guidelines include the tuberculin skin test as a screening test for tuberculosis infection with mention of new diagnostic tests based on the in vitro detection of gamma interferon (IGRA) for certain cases. The purpose of this guide is to establish common criteria for IGRA tests, as a supplementary aid to the tuberculin skin test in health care workers, from the evidence available today. Recommendations for its use have been adapted to the different situations faced by the professionals involved in monitoring the health of health workers.


Med Clin (Barc)


Medicina clinica


Casas I,Dominguez J,Rodríguez S,Matllo J,Altet N,SEPAR.,GEIM.,SEIMC.,AEEMT.,Programa de Prevención y control de la Tuberculosis (Catalan Public Health Agency).




Has Abstract


2015-12-21 00:00:00














  • [Susceptibility to varicella among health care workers. Acceptability and response to vaccination].

    abstract:BACKGROUND AND OBJECTIVE:To determine the prevalence of health care workers (HCW) susceptibility to varicella zoster virus (VZV). As a secondary objective, we describe the immunogenicity and reactogenicity of the vaccine. SUBJECTS AND METHODS:A multicenter analytic cross-sectional study was conducted in 5 hospitals in...

    journal_title:Medicina clinica

    pub_type: 杂志文章,多中心研究


    authors: García-Basteiro AL,Bayas JM,Campins M,Torres M,Serra C,Varela P,Barbé E,Vidal J,Grupo de Estudio de la Varicela en Hospitales de Cataluña.

    更新日期:2011-09-24 00:00:00

  • [Paraoxonase, something more than an enzyme?].

    abstract::Coronary heart disease is one of the major causes of death in developed countries. The hypothesis that peroxidation of low density lipoproteins (LDL) may be the initial step of the atherosclerotic process has promoted numerous studies aimed at investigating the mechanisms by which the body protects itself from such ox...

    journal_title:Medicina clinica

    pub_type: 杂志文章,评审


    authors: Canales A,Sánchez-Muniz FJ

    更新日期:2003-10-25 00:00:00

  • [Evolution of serologically confirmed cases of mumps in the Madrid community, Spain, during a period of 7 years (2000--2006)].

    abstract:BACKGROUND AND OBJECTIVE:The aim of this study was to describe the evolution of serologically confirmed cases of mumps in the Madrid Community from 2000 to 2006. PATIENTS AND METHOD:Cases with data about age, sex and with samples obtained < or = 30 days after the onset of symptoms were included. IgM determination was ...

    journal_title:Medicina clinica

    pub_type: 杂志文章


    authors: Sanz JC,de Ory F,Fernández M,Herranz N,Méndez N,Ramírez R

    更新日期:2008-03-08 00:00:00

  • [Alcohol-dependent patients with benzodiazepine abuse: its relation to personality disorders and neuropsychological impairment].

    abstract:BACKGROUND AND OBJECTIVE:Alcohol and drug dependent patients present a higher psychiatric comorbidity, which increases according to the number of drugs. Moreover, there are complications from the treatment and the prognosis is aggravated. We aimed to observe the differences regarding personality disorders (PD) and cogn...

    journal_title:Medicina clinica

    pub_type: 杂志文章


    authors: Monràs M,Mondón S,Jou J

    更新日期:2008-05-17 00:00:00

  • [Assessing COPD-associated morbidity: factors of prognosis].

    abstract:BACKGROUND AND OBJECTIVE:Forced respiratory volume in first second spirometry is currently used to diagnose chronic obstructive pulmonary disease. However, this technique does not always provide a reliable short-term prognosis, especially in patients with associated morbidity. We propose that specific health-related qu...

    journal_title:Medicina clinica

    pub_type: 杂志文章


    authors: Vega Reyes JA,Montero Pérez-Barquero M,Sánchez Guijo P

    更新日期:2004-03-06 00:00:00

  • [Prevalence of bacterial vaginosis in an obstetric population of Barcelona].

    abstract:OBJECTIVES:To investigate the prevalence and risk factors of bacterial vaginosis (BV) in a pregnant population of Barcelona (Spain). MATERIAL AND METHODS:301 pregnant women controlled in the Hospital Clinic i Provincial (HCP) of Barcelona were enrolled in the study. Complete epidemiological information, and vaginal sa...

    journal_title:Medicina clinica

    pub_type: 杂志文章


    authors: Martínez de Tejada B,Coll O,de Flores M,Hillier SL,Landers DV

    更新日期:1998-02-21 00:00:00

  • [Spironolactone in patients with resistant hypertension].

    abstract:BACKGROUND AND OBJECTIVE:The aim of the study was to assess the effect of adding spironolactone to hypertensive resistant (HTR) patients and characterize those who respond effectively. PATIENTS AND METHOD:Observational retrospective study on outpatients with HTR (being treated with at least 3 drugs at full doses, one ...

    journal_title:Medicina clinica

    pub_type: 杂志文章


    authors: Rodilla E,Costa JA,Pérez-Lahiguera F,González C,Pascual JM

    更新日期:2008-10-04 00:00:00

  • [Bone metabolism and fracture risk in anorexia nervosa].

    abstract::The prevalence of anorexia nervosa has increased in recent years and a large proportion of patients with this disorder have low bone density at diagnosis and, therefore, an increased risk of early and late fractures. The mechanism of bone loss in anorexia nervosa is not well understood, yet it likely includes hypogona...

    journal_title:Medicina clinica

    pub_type: 杂志文章,评审


    authors: Fernández Soto ML,González Jiménez A,Varsavsky M

    更新日期:2010-07-17 00:00:00

  • [Surveillance of nosocomial infection at a regional++ hospital. Results of incidence and prevalence studies in a 2 years' experience].

    abstract:BACKGROUND:The most appropriate methods for surveillance of nosocomial infection (NI) in hospitals with less than 250 beds remain to be elucidated. The aims of this study were to investigate the differences between the results found in a study in incidence (IS) and in another concerning prevalence (PS) carried out in a...

    journal_title:Medicina clinica

    pub_type: 杂志文章


    authors: Javaloyas M,García D,Casasín T,Colomer J,Bonfill X,Brotons C,Rué M

    更新日期:1993-01-16 00:00:00

  • [Incrusted cystitis with isolation of Corynebacterium group D2].

    abstract::Three cases of encrusted cystitis caused by Corynebacterium group D2 are described. The vesical damage previous to the establishment of this bacteria is noteworthy and the very rapid increase in urease activity explains the pathogenesis of the situation. Thus allowing for its identification and is relevant to treatmen...

    journal_title:Medicina clinica

    pub_type: 杂志文章


    authors: Fernández Natal MI,García Díez F,Salas Valién JS,Cachón García F,Soriano García F

    更新日期:1992-03-21 00:00:00

  • [Genetic polymorphisms and lung cancer risk: a case-control study].

    abstract:BACKGROUND AND OBJECTIVE:The smoke fume, principal factor in the development of lung cancer, causes the expression of certain cytokines, including interleukin 4, 6, 8 and 10, which may act by inhibiting apoptosis and interfere cellular repair mechanisms and angiogenesis. To determine the possible relationship between g...

    journal_title:Medicina clinica

    pub_type: 杂志文章


    authors: Jiménez-Massa AE,Alonso-Sardón M,Menacho-Miguel JA,Mirón-Canelo JA,González-Sarmiento R

    更新日期:2014-08-04 00:00:00

  • [Multiple chemical sensitivity: study of 52 cases].

    abstract:BACKGROUND AND OBJECTIVE:Multiple chemical sensitivity (MCS) is characterized by a loss of tolerance to various environmental chemicals. The objective of this study was to describe patients with MCS seen in our hospital. PATIENTS AND METHOD:Patients consecutively seen by the Toxicology and Chronic Fatigue Units who pr...

    journal_title:Medicina clinica

    pub_type: 杂志文章


    authors: Nogué S,Fernández-Solá J,Rovira E,Montori E,Fernández-Huerta JM,Munné P

    更新日期:2007-06-16 00:00:00

  • [Analysis of TRPV1 gene polymorphisms in Spanish patients with neuropathic pain].

    abstract:BACKGROUND AND OBJECTIVE:The vanilloid receptor TRPV1 is a molecular integrator of painful stimuli. Several recent studies suggest that TRPV1 may play a role in development and maintenance of chronic pain. In an attempt to determine if genotypic variations in TRPV1 gene could be involved in the susceptibility to suffer...

    journal_title:Medicina clinica

    pub_type: 杂志文章


    authors: Armero P,Muriel C,López M,Santos J,González-Sarmiento R

    更新日期:2012-06-02 00:00:00

  • Recurrent urinary tract infections: from pathogenesis to prevention.

    abstract::Urinary tract infections are highly prevalent among women and when they are recurrent they can lead to patient discomfort and high healthcare costs, and they represent one of the most frequent causes of antibiotic consumption. There are several options to prevent RUTI which include both antibiotic treatment (continuou...

    journal_title:Medicina clinica

    pub_type: 杂志文章,评审


    authors: Pigrau C,Escolà-Vergé L

    更新日期:2020-08-28 00:00:00

  • [Prevalence of hepatitis B and hepatitis A virus infection among health sciences students in Catalonia, Spain].

    abstract:BACKGROUND:To know current hepatitis B (HBV) and hepatitis A (HAV) infection status among a group of health sciences students during 1990-1993 period. SUBJECTS AND METHODS: SUBJECTS:1,734 health sciences students during 1990-1991, 1992-1993 and 1993-1994 academic years. MAIN OUTCOME MEASURES:demographic variables, v...

    journal_title:Medicina clinica

    pub_type: 杂志文章


    authors: Bayas JM,Bruguera M,Vilella A,Carbó JM,Vidal J,Navarro G,Nebot X,Prat A,Salleras L

    更新日期:1996-09-14 00:00:00

  • [Twice-daily and weekly exenatide: Clinical profile of two pioneer formulations in incretin therapy].

    abstract::GLP-1 receptors agonists have been a substantial change in treatment of type 2 diabetes mellitus, and its weekly administration has broken pre-established schemes. Daily exenatide is administered every 12 hours (BID) subcutaneously, while weekly exenatide is administered once a week. Both molecules share a common mech...

    journal_title:Medicina clinica

    pub_type: 杂志文章,评审


    authors: Lecube A,Bueno M,Suárez X

    更新日期:2014-01-01 00:00:00

  • [Therapeutic control and quality of life in coronary artery bypass surgery patients].

    abstract:BACKGROUND:Description of measures of secondary prevention and of health related quality of life one year after the intervention in patients undergoing coronary artery bypass surgery. PATIENTS AND METHOD:One year follow up prospective study in patients undergoing first coronary bypass surgery without associated proced...

    journal_title:Medicina clinica

    pub_type: 杂志文章


    authors: Brotons Cuixart C,Moral Peláez I,Permanyer Miralda G,Ribera Solé A,Cascant Castelló P,Estudio CIRCORCA.

    更新日期:2001-02-24 00:00:00

  • [Spanish public opinion concerning organ donation and transplantation].

    abstract:BACKGROUND:Information, beliefs, attitudes and the motivations of the Spanish population regarding organ donation and transplantation were studied to facilitate possible programs directed at the promotion of organ donation. METHODS:The Psychosocial Aspects of Donation Questionnaire (PADQ) was applied by personal inter...

    journal_title:Medicina clinica

    pub_type: 杂志文章


    authors: Martínez JM,Martín A,López JS

    更新日期:1995-10-07 00:00:00

  • [Coronary ectasis: another form of atherosclerosis].

    abstract::In a review of 3,693 coronary angiographies carried out in our department for suspected coronary artery disease we evaluated the 69 patients (1.86%) in whom lesions of coronary ectasia were found. Most of them (n = 51) had associated stenotic lesions and only 18 patients had isolated ectasia. The most common localizat...

    journal_title:Medicina clinica

    pub_type: 杂志文章,评审


    authors: Aparici M,Peteiro J,Fernández de Almeida CA,Hidalgo R,Alzamora P,Barba J,Alegría E

    更新日期:1989-10-07 00:00:00

  • [Treatment and control of patients with phenylketonuria: results from the Collaborative Group of Spanish Follow-up Units].

    abstract:BACKGROUND AND OBJECTIVE:To evaluate the management of phenylketonuria (PKU) in Spanish metabolic units and to develop a patients registry. PATIENTS AND METHODS:PKU patients diagnosed and/or followed up in Spain, with phenylalanine values before treatment > 360 μmol/L. Registered anonymous data are those yielded by th...

    journal_title:Medicina clinica

    pub_type: 杂志文章,多中心研究


    authors: Campistol J,González MJ,Gutiérrez AP,Vilaseca MA,Grupo Colaborativo de Unidades de Seguimiento Españolas.

    更新日期:2012-03-03 00:00:00

  • [Anaesthesia and thromboembolic disease].

    abstract::Currently, pharmacological thromboprophylaxis is frequently required in patients undergoing surgery, due to the high risk of deep venous thrombosis in the perioperative period. The administration of these anticoagulant agents (in Spain, usually low molecular weight heparins or fondaparinux, and in future, probably als...

    journal_title:Medicina clinica

    pub_type: 杂志文章,评审


    authors: Llau JV,Sapena ML,López Forte C,Ferrandis R

    更新日期:2008-11-01 00:00:00

  • [Is medical care adequate in cases of the common cold? The result of an evaluation in 8 health centers].

    abstract:BACKGROUND:In this study the quality of health care provided in cases of the common cold and similar was studied. These diseases were selected to seek opportunities for improvement for health care professionals by the nominal group technique. METHODS:A retrospective study of the health care procedures was carried out ...

    journal_title:Medicina clinica

    pub_type: 杂志文章


    authors: Saturno Hernández PJ,Gascón Cánovas JJ,Fonseca Miranda Y

    更新日期:1995-04-15 00:00:00

  • [Diagnosis, biomarkers and biochemical alterations in Gaucher's disease].

    abstract::Gaucher's disease (GD) is an inherited metabolic disease due to lack of activity of the enzyme betaglucocerebrosidase. The diagnosis of GD is usually performed by fluorimetric analysis of the enzyme betaglucocerebrosidase. It can also be done by measuring the activity of tandem mass spectrometry. This enzyme can be an...

    journal_title:Medicina clinica

    pub_type: 杂志文章


    authors: Gort L,Coll MJ

    更新日期:2011-09-01 00:00:00

  • [Neutrophil extracellular traps: a 2-faced host defense mechanism].

    abstract::Neutrophils play a key role in the innate immune system, providing the first line of host defense. In addition to their ability to eliminate pathogens by phagocytosis and antimicrobial secretions, it has recently been shown that neutrophils can trap and kill microorganisms by the release of extracellular structures co...

    journal_title:Medicina clinica

    pub_type: 杂志文章,评审


    authors: Camicia G,de Larrañaga G

    更新日期:2013-01-19 00:00:00

  • [Smoking paradox in acute coronary syndrome without ST-segment elevation].

    abstract:BACKGROUND AND OBJECTIVE:Although smoking habit is a well-known cardiovascular risk factor, it has been described that smokers admitted because of myocardial infarction have better prognosis than non smoker patients, which is known as "the smoking paradox". The purpose of our work is to investigate whether this phenome...

    journal_title:Medicina clinica

    pub_type: 杂志文章


    authors: Amor-Salamanca A,Devesa-Cordero C,Cuesta-Díaz A,Carballo-López MC,Fernández-Ortiz A,García-Rubira JC

    更新日期:2011-02-19 00:00:00

  • [Low levels of serotonin in serum correlates with severity of fibromyalgia].

    abstract:OBJECTIVE:Fibromyalgia (FM) is a chronic pain syndrome of unknown etiology, which affects predominantly women. Among the alterations that have been implicated in the pathophysiology of FM, there have been postulated disturbances in serotonin levels and metabolism, and their implication in symptoms. The aim of the prese...

    journal_title:Medicina clinica

    pub_type: 杂志文章


    authors: Cordero MD,Alcocer-Gómez E,Cano-García FJ,de Miguel M,Sánchez-Alcázar JA,Moreno Fernández AM

    更新日期:2010-11-13 00:00:00

  • [The measurement of health related quality of life].

    abstract::The measurement of health-related quality of life (HRQOL) plays a very important role in the study of health outcomes, particularly in effectiveness studies. Nevertheless, the nature of these studies implies a series of challenges in the use of HRQOL instruments, due to the type of comparisons made, the heterogeneity ...

    journal_title:Medicina clinica

    pub_type: 杂志文章


    authors: Herdman M

    更新日期:2000-01-01 00:00:00

  • [Folic acid ingestion and associated factors in adult women 15-44 years of age in the Valencian Community].

    abstract:BACKGROUND:A low folic acid (FA) intake may increase the risk of neural tube defects (NTD). We estimated the proportion of women with a FA intake < 400 micrograms/day, at the Valencian Region, exploring those factors associated with a FA intake < 400 micrograms/day. SUBJECTS AND METHOD:Daily FA intake was estimated fo...

    journal_title:Medicina clinica

    pub_type: 杂志文章


    authors: Vioque J,Quiles J,García de la Hera M,Guillén M,Ponce E,Muñoz P

    更新日期:2000-03-25 00:00:00

  • [Use of complementary and alternative medicine and drug abuse in patients with inflammatory bowel disease].

    abstract:BACKGROUND AND OBJECTIVE:The use of complementary and alternative medicine (CAM) is increasing in last years. Studies performed out of Spain have reported rates of CAM use of 40-50% among IBD patients. There are no available data on drug abuse among IBD patients. The aims of our study were to evaluate the rate and asso...

    journal_title:Medicina clinica

    pub_type: 杂志文章


    authors: García-Planella E,Marín L,Domènech E,Bernal I,Mañosa M,Zabana Y,Gassull MA

    更新日期:2007-01-20 00:00:00

  • [Serum lipoprotein (a) levels during treatment with LDL apheresis for homozygous familial hypercholesterolemia].

    abstract:BACKGROUND:Due to the double atherogenic and antifibrinolytic action of lipoprotein (a) (Lp [a]) and its predictive value of cardiovascular disease in hypercholesterolemic patients, we document in the present work the changes in Lp (a) levels of a patient with homozygous familial hypercholesterolemia after one year of ...

    journal_title:Medicina clinica

    pub_type: 杂志文章


    authors: Lasunción MA,Teruel JL,Alvarez JJ,Gómez-Coronado D,Ortuño J,Herrera E

    更新日期:1992-10-31 00:00:00