[Costs of health care resources of ambulatory-care patients diagnosed with Alzheimer's disease in Spain].

Abstract:

BACKGROUND:The annual consumption and costs of the health care resources used by ambulatory Alzheimer's disease patients were estimated. Patients were classified according to the degree of severity of the disease using Folstein's Mini Mental State Examination scale. The sociodemographic characteristics of both patients and their careers were described. PATIENTS AND METHODS:Patients with an established diagnosis of Alzheimer's disease according to NINCDS/ADRDA criteria were included in the study. Information on the use of health and non-health care resources consumed during the last 12 months was recorded. The following scales were administered: MMSE, Global Deterioration Scale, Rapid Disability Rating Scale and Hachinski's scale modified by Rosen. Finally, the time dedicated by careers to look after the Alzheimer's disease patients was recorded. RESULTS:A total of 337 patients were considered to be valid for the analysis with an average of 72 (8.4) years and with an average duration of the disease of 48.3 (35.7) months. The average annual cost per patient was 3,194,664 ptas. The average cost per patient in the group with MMSE > 18 was 2,119,889 ptas; 2,723,159 ptas. in those with MMSE 12-18 and 3,676,707 ptas. in the MMSE < 12 group. CONCLUSIONS:In patients with Alzheimer's disease an increase in cost directly related to functional cognition state was observed. The most important cost component was that imputed to value time dedicated by principal career.

journal_name

Med Clin (Barc)

journal_title

Medicina clinica

authors

Boada M,Peña-Casanova J,Bermejo F,Guillén F,Hart WM,Espinosa C,Rovira J

keywords:

subject

Has Abstract

pub_date

1999-11-27 00:00:00

pages

690-5

issue

18

eissn

0025-7753

issn

1578-8989

journal_volume

113

pub_type

杂志文章
  • [Immunohistochemical study of inflammatory infiltrates in minor salivary glands in Sjögren's syndrome and other autoimmune diseases].

    abstract:BACKGROUND:A study of the phenotype, activation and adhesive cells factors and cytokines in minor salivary glands in patients with primary Sjögren's syndrome (pSS), secondary Sjögren's syndrome (sSS) and autoimmune diseases (AD) without Sjögren's syndrome. PATIENTS AND METHODS:We have studied the minor salivary glands...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Tomás S,Coll J,Reth P,Corominas JM

    更新日期:1998-11-28 00:00:00

  • [The measurement of health related quality of life].

    abstract::The measurement of health-related quality of life (HRQOL) plays a very important role in the study of health outcomes, particularly in effectiveness studies. Nevertheless, the nature of these studies implies a series of challenges in the use of HRQOL instruments, due to the type of comparisons made, the heterogeneity ...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Herdman M

    更新日期:2000-01-01 00:00:00

  • [Current controversies in glycemic control targets. What do the results of the latest clinical trials tell us about the approach to type 2 diabetes mellitus?].

    abstract::The aim of this article is to discuss the implications of the results obtained in the latest large-scale clinical trials designed to evaluate the effect of intensive glycemic control on the vascular complications associated with type 2 diabetes mellitus. The current scientific evidence is reviewed and the implications...

    journal_title:Medicina clinica

    pub_type: 杂志文章,评审

    doi:10.1016/S0025-7753(10)70025-7

    authors: Mauricio D,Rius F

    更新日期:2010-09-01 00:00:00

  • [Distribution of serotypes A and B of Candida albicans in 502 strains isolated from pathological specimens].

    abstract:BACKGROUND:Candida albicans is distributed in at least two serological groups (A and B) depending on its antigenic structure. These characteristics have been used to investigate the epidemiology of candidiasis. No information is available in this country about the distribution of these serotypes in a general population...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Torres-Rodríguez JM,Nicolás MC,Madrenys N,Gallach C

    更新日期:1991-06-01 00:00:00

  • [Predictive factors of the persistence of sarcoidosis activity 2 years after diagnosis].

    abstract:BACKGROUND:The prognosis of sarcoidosis is difficult to predict. In general, sarcoidosis is considered as chronic when it remains active for over 2 years. The aim of this study was to analyze predictive factors in the persistence of sarcoidosis activity 2 years after diagnosis. METHODS:One hundred fifty-five patients ...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Mañá J,Badrinas F,Manresa F,Valverde J,Fernández-Nogués F

    更新日期:1991-12-07 00:00:00

  • [Long-term effects of continuous positive airway pressure treatment on subclinical atherosclerosis in obstructive sleep apnoea syndrome].

    abstract:BACKGROUND AND OBJECTIVE:Obstructive sleep apnoea (OSA) is associated with an increased risk of cardiovascular disease. Our objective was to evaluate subclinical atherosclerosis in OSA patients and the effect of continuous positive airway pressure (CPAP) treatment on carotid intima-media thickness (cIMT). PATIENTS AND...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/j.medcli.2016.03.032

    authors: Català R,Ferré R,Cabré A,Girona J,Porto M,Texidó A,Masana L

    更新日期:2016-07-01 00:00:00

  • [Tuberculosis in chronic myeloproliferative syndromes: its incidence and principle characteristics in a series of 562 patients].

    abstract:BACKGROUND:Incidence analysis of tuberculosis in a series of 562 patients with chronic myeloproliferative syndrome (CMPS). 344 had chronic myelocytic leukemia, 91 polycythemia vera, 70 idiopathic myelofibrosis and 57 essential thrombocythemia. METHODS:The association between CMPS and tuberculosis was evaluated with th...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Tassies D,Cervantes F,Nicolás JM,Feliu E,Soriano E,Rozman C

    更新日期:1991-03-09 00:00:00

  • [Effects of aerobic exercise program and relaxation techniques on anxiety, quality of sleep, depression, and quality of life in patients with fibromyalgia: a randomized controlled trial].

    abstract:BACKGROUND AND OBJECTIVE:Fibromyalgia is considered as a combination of physical, psychological and social disabilities. The purpose of the present study was to determine the benefits of aerobic exercise program and progressive relaxation techniques on anxiety, quality of sleep, depression and quality of life in patien...

    journal_title:Medicina clinica

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.medcli.2010.09.045

    authors: Arcos-Carmona IM,Castro-Sánchez AM,Matarán-Peñarrocha GA,Gutiérrez-Rubio AB,Ramos-González E,Moreno-Lorenzo C

    更新日期:2011-10-08 00:00:00

  • [The usefulness of the teriparatide acetate (Parathar) infusion test in the diagnosis of pseudohypoparathyroidism].

    abstract::In pseudohypoparathyroidism there is a resistance to the action of the parathormone in its target organs. Patients with this disease show clinical and laboratory data of hypoparathyroidism with normal or high levels of parathormone. Three types of pseudohypoparathyroidism are known according to the site in which the d...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Rius F,Salinas I,Reverter JL,Pizarro E,Lucas A

    更新日期:1993-09-18 00:00:00

  • [Chronic hepatitis E].

    abstract::The hepatitis E virus is an RNA virus with 4 genotypes. Genotypes 1 and 2 only affect humans and produce epidemic acute hepatitis in endemic regions (Asia and Africa). Genotypes 3 and 4 are considered a zoonosis and produce episodic acute hepatitis in non-endemic areas (America and Europe). However, in the last 3 year...

    journal_title:Medicina clinica

    pub_type: 杂志文章,评审

    doi:10.1016/j.medcli.2011.02.003

    authors: González Tallón AI,Moreira Vicente V,Mateos Lindemann ML

    更新日期:2012-02-04 00:00:00

  • [Cerebral tuberculoma. Report of 8 cases].

    abstract::A series of eight patients with cerebral tuberculoma seen between 1980 and 1990 is reported. Headache was the leading clinical finding, followed by focal neurological findings and seizures. Papilledema was the most uniform examination finding associated with intracranial hypertension. Five patients had another localiz...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Martínez Lacasa JT,Burillo J,Niubó R,Rufí G,Podzamczer D,Mariscal A,Reñé R,Fernández Nogués F

    更新日期:1991-07-06 00:00:00

  • [Treatment of solitary toxic thyroid nodule with 131I: results in 43 patients].

    abstract:BACKGROUND:Evaluation of the therapy with high-dose 131I in solitary toxic thyroid adenoma, with particular attention to the effects on thyroid function and on the nodular size. METHODS:A retrospective study of 43 patients with solitary thyroid nodule treated with radioactive iodine (mean dose 26.6 mCi, range 10-35) a...

    journal_title:Medicina clinica

    pub_type: 杂志文章,评审

    doi:

    authors: Marín JF,Maraña G,Salto L,Astigarraga B,Estrada FJ,Lucas T,Barceló B

    更新日期:1991-05-18 00:00:00

  • [Congenital hepatorenal polycystic disease with unusual long survival (author's transl)].

    abstract::The authors report a case of hepatorenal polycystic disease discovered in the course of a routine physical examination. The patient was asymptomatic and the progression of the disease was extremely low. The existence of the disorder, however, was confirmed in the autopsy. Although hepatorenal polycystic disease is a r...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Bofill D,Cabrer B,Grau A,Llebot J,Montis R,Vivancos J,Balcells A

    更新日期:1980-02-10 00:00:00

  • Shared decision-making in advanced chronic kidney disease in the elderly.

    abstract::Chronic kidney disease is common in people >65years of age. The development and improvement of dialysis techniques has allowed its generalisation to the entire population, when there is a situation of terminal nephropathy, without limit of use due to chronological age. Decision making in elderly patients with advanced...

    journal_title:Medicina clinica

    pub_type: 杂志文章,评审

    doi:10.1016/j.medcli.2018.07.011

    authors: Heras Benito M,Fernández-Reyes Luis MJ

    更新日期:2019-03-01 00:00:00

  • [Factors associated with sharing syringes among street-recruited injecting drug users].

    abstract:BACKGROUND AND OBJECTIVE:To estimate the prevalence of risk behaviors related to drug use and to identify factors associated with of accepting and passing on used syringes among intravenous drug users (IDU) recruited in Barcelona city and other surrounding areas in 2004. SUBJECTS AND METHOD:A cross-sectional study of ...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1157/13093723

    authors: Folch C,Meroño M,Casabona J

    更新日期:2006-10-14 00:00:00

  • [Parotiditis in postvaccination period. Epidemiologic pattern and vaccine effectiveness in an epidemic outbreak].

    abstract:BACKGROUND:Upon the detection of an excess number of cases of parotiditis in La Almolda (Zaragoza) a descriptive study of the epidemic was carried out with vaccination efficacy being quantified. METHODS:The definition and system of detection of the cases was established. To calculate the rate of infection the availabl...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Guimbao Bescós J,Moreno Marín MP,Gutiérrez Colás V,Pac Sá MR,Arribas Monzón F

    更新日期:1992-09-19 00:00:00

  • [The molecular genetics of the fragile X syndrome. Its molecular diagnosis by DNA probes].

    abstract:BACKGROUND:The cytogenetic analysis of the fragile X affected shows a break point in the q27.3 region of chromosome X. However many carrier females and normal carrier males remain refractory to cytogenetic diagnosis. New DNA probes tightly linked to the fragile X point are now available allowing by the familiar RFLP an...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Giné R,Espinás ML,Antich J,Carballo M

    更新日期:1992-02-01 00:00:00

  • [New advances in contraception and sterilization].

    abstract::The advances in contraceptive and sterilization methods likely to be available within the next few years will probably consist of improvements of existing methods rather than revolutionary new techniques. Among female vaginal methods, vaginal sponges incorporating spermicides have been constructed of collagen or poly...

    journal_title:Medicina clinica

    pub_type: 杂志文章,评审

    doi:

    authors: Iglesias Cortit L

    更新日期:1985-11-02 00:00:00

  • Type 1 autoimmune hepatitis in a patient with microscopic polyangiitis: challenges in diagnosis and treatment.

    abstract:BACKGROUND AND OBJECTIVE:Autoimmune diseases/autoantibodies tend sometimes to cumulate in the same individual, probably as a consequence of defects in immune regulation with breakdown of self-tolerance. Autoimmune hepatitis and microscopic polyangiitis have been occasionally reported with other autoimmune diseases, but...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/j.medcli.2010.10.015

    authors: Prieto-González S,Cardellach F,Estruch R,Miquel R,Grau JM,Cid MC

    更新日期:2011-03-26 00:00:00

  • [Evaluation on the compliance of the metabolic control aims in outpatients with type 2 diabetes mellitus in Spain. The TranSTAR study].

    abstract:BACKGROUND AND OBJECTIVE:A good metabolic control of patients with type 2 diabetes mellitus (DM2) will likely contribute to a decrease of their cardiovascular (CV) risk. Our aim was (1) to evaluate the degree of metabolic control with regard to glycemia, lipidemia and blood pressure (BP) and (2) to describe the prevale...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/s0025-7753(03)73735-x

    authors: de la Calle H,Costa A,Díez-Espino J,Franch J,Goday A

    更新日期:2003-04-05 00:00:00

  • Effect of alcohol and its metabolites in lung cancer: CAPUA study.

    abstract:BACKGROUND AND OBJECTIVE:Alcohol and its metabolites play an important role in carcinogenesis. This effect could be modulated by polymorphisms in genes encoding enzymes involved in the metabolism of alcohol and folate. Therefore, we analyzed the effect of alcohol consumption and ADH1B Arg48His, ADH1B Arg370Cys, ADH1C I...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/j.medcli.2016.12.033

    authors: Álvarez-Avellón SM,Fernández-Somoano A,Navarrete-Muñoz EM,Vioque J,Tardón A

    更新日期:2017-06-21 00:00:00

  • [Spironolactone in patients with resistant hypertension].

    abstract:BACKGROUND AND OBJECTIVE:The aim of the study was to assess the effect of adding spironolactone to hypertensive resistant (HTR) patients and characterize those who respond effectively. PATIENTS AND METHOD:Observational retrospective study on outpatients with HTR (being treated with at least 3 drugs at full doses, one ...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1157/13126215

    authors: Rodilla E,Costa JA,Pérez-Lahiguera F,González C,Pascual JM

    更新日期:2008-10-04 00:00:00

  • [Q fever outbreak in an urban area following a school-farm visit].

    abstract:BACKGROUND AND OBJECTIVE:The aim of this study was to describe an outbreak of Q fever in a group of people (day care centre for mental-handicapped individuals) previously exposed to animals in a school-farm. PATIENTS AND METHOD:A retrospective cohort study among the 25 mental-handicapped individuals and the 30 workers...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1157/13087697

    authors: de los Ríos-Martín R,Sanz-Moreno JC,Martín-Martínez F,Tébar-Betegón MA,Cortés-García M,Escudero-Nieto R

    更新日期:2006-04-22 00:00:00

  • [Influence of highly active antiretroviral therapy on the evolution of AIDS-associated Kaposi's sarcoma].

    abstract:BACKGROUND:To evaluate the highly active antiretroviral therapy (HAART) in the Kaposi's sarcoma evolution. PATIENTS AND METHOD:Retrospective analysis of a cohort of 126 HIV infected patients suffering from Kaposi's sarcoma with or without HAART. Clinical evolution, immunological status (CD4+ cell count) and response t...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/s0025-7753(00)71677-0

    authors: Mercè Alsina M,Bulla F,Conill C,Mallolas J,Bernardo Pérez-Cuevas J,Lecha M

    更新日期:2000-12-02 00:00:00

  • Direct oral anticoagulants: An update.

    abstract::Vitamin K antagonists were the only choice for chronic oral anticoagulation for more than half a century. Over the past few years, direct oral anticoagulants have emerged, including one direct thrombin inhibitor (dabigatran etexilate) and three factor Xa inhibitors (apixaban, edoxaban and rivaroxaban). In randomised c...

    journal_title:Medicina clinica

    pub_type: 杂志文章,评审

    doi:10.1016/j.medcli.2017.11.042

    authors: Franco Moreno AI,Martín Díaz RM,García Navarro MJ

    更新日期:2018-09-14 00:00:00

  • [Gender differences in early reperfusion treatment after myocardial infarction].

    abstract:BACKGROUND AND OBJECTIVE:Clinical variability in myocardial infarction (MI) regarding age, comorbidities and atypical symptoms could determine gender differences in inhospital care. This study analyzes the magnitude and determinants of differences between men and women in early reperfusion therapy in people hospitalize...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/s0025-7753(07)72497-1

    authors: Aldasoro E,Calvo M,Esnaola S,Hurtado de Saracho I,Alonso E,Audicana C,Arós F,Lekuona I,Arteagoitia JM,Basterretxea M,Marrugat J,IBERICA-País Vasco Group.

    更新日期:2007-01-27 00:00:00

  • [Effect of HAART on HCV viral load in the first three years of follow-up].

    abstract:BACKGROUND AND OBJECTIVE:Highly active antiretroviral therapy (HAART) has been considered to be ineffective in controlling hepatitis C viremia in the first year of treatment. The present study evaluates the effect of prolonged HAART upon HCV-VL. PATIENTS AND METHOD:We selected those cases with positive serology for HC...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/s0025-7753(03)73970-0

    authors: Tornero C,Gimeno C,Igual R,Santamaría A,Gil E,Rull S

    更新日期:2003-10-04 00:00:00

  • [Bronchiectasis in the elderly. Study of serum levels of immunoglobulin G subclasses].

    abstract:BACKGROUND AND OBJECTIVE:To analyze the serum levels of immunoglobulin G (IgG) subclasses in a broad range of elderly patients with bronchiectasis. PATIENTS AND METHOD:Data were collected from all patients who had a high-resolution chest computerized axial tomography diagnosis of bronchiectasis in our center. We gathe...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1157/13111419

    authors: Martínez-García MA,Román-Sánchez P,Perpiñá-Tordera M,Soler-Cataluña JJ,Saura-Vinuesa A,Yago M,Pastor MJ

    更新日期:2007-10-20 00:00:00

  • [Legionnaire's disease outbreak].

    abstract:BACKGROUND AND OBJECTIVE:To describe an outbreak of Legionella pneumophila serogroup 1 in Mataró, Catalunya, Spain, in August 2002. The source of the microorganism was a cooling tower. PATIENTS AND METHOD:Prospective and observational study with analysis of epidemiological, clinical, and microbiological data. RESULTS...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/s0025-7753(06)71871-1

    authors: Barrufet-Barqué MP,Sauca-Subias G,Force-Sanmartín L,Felip-Benach A,Martínez-Pérez E,Capdevila-Morell JA

    更新日期:2006-02-11 00:00:00

  • [Carboxyhemoglobin levels and risk factors of carbon monoxide poisoning in children;].

    abstract:BACKGROUND:To determine carboxyhemoglobin levels and to investigate carbon monoxide poisoning risk in children. PATIENTS AND METHODS:We determine carboxyhemoglobin blood levels by cooximetry in 65 children, between 15 days and 15 years attended in a pediatric emergency section. We analyze carbon monoxide risk factors ...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Vázquez P,López-Herce J,Galarón P,Merello Godino C

    更新日期:1997-01-11 00:00:00