Abstract：
BACKGROUND:To evaluate the highly active antiretroviral therapy (HAART) in the Kaposi's sarcoma evolution. PATIENTS AND METHOD:Retrospective analysis of a cohort of 126 HIV infected patients suffering from Kaposi's sarcoma with or without HAART. Clinical evolution, immunological status (CD4+ cell count) and response to therapy (HIV-RNA plasma viral load and human herpes-8 virus determination). RESULTS:All patients without HAART died and the cumulate probability survival (SD) among those who received HAART was 2.078 (74) days. The CD4+ count at baseline in the HAART group was 130 (125) * 106/l and the HIV-RNA viral load was 196,818 (244,195) copies/ml while at the moment of the clinical response was 235 (209) * 106/l CD4 + and 2,629 (6.444) copies/ml, respectively. CONCLUSION:HAART prolongs survival in HIV patients suffering from Kaposi's sarcoma. There is a clear relationship among clinical response, HAART and immunological recovery.
journal_name
Med Clin (Barc)journal_title
Medicina clinicaauthors
Mercè Alsina M,Bulla F,Conill C,Mallolas J,Bernardo Pérez-Cuevas J,Lecha Mdoi
10.1016/s0025-7753(00)71677-0keywords:
subject
Has Abstractpub_date
2000-12-02 00:00:00pages
736-7issue
19eissn
0025-7753issn
1578-8989pii
S0025-7753(00)71677-0journal_volume
115pub_type
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