Abstract：
BACKGROUND AND OBJECTIVES:Strategies to improve the efficiency of bronchoalveolar lavage (BAL) are needed. We conducted a study to establish the diagnostic value of BAL in patients with hematological malignancies and pulmonary infiltrates. PATIENTS AND METHODS:The correlation of cytologic and flow cytometric study of BAL with the microbiological findings and the clinical evolution was determined. RESULTS:Seventy BAL were performed and flow cytometric study was analyzed in 23 of them. Fifty-three patients did not present any adverse event attributable to BAL. Anti-infectious therapy was modified in 64 (91%) patients. T lymphocyte count >0.3×109/l in peripheral blood was associated with longer OS at 3 years (53 vs. 22%, p=.009). Higher CD4 (>20/μL) and CD8 (>35/μL) lymphocyte counts in the BAL were associated with a longer OS at 3 years: 82 vs. 21% (p=.030) and 80 vs. 23% (p=.059). CONCLUSIONS:Our study confirms the clinical value of BAL for treatment decision making in patients with hematological malignancies and acute respiratory failure.
journal_name
Med Clin (Barc)journal_title
Medicina clinicaauthors
Ferrà C,Xicoy B,Castillo N,Morgades M,Juncà J,Andreo F,Millá F,Feliu E,Ribera JMdoi
10.1016/j.medcli.2016.10.045subject
Has Abstractpub_date
2017-04-07 00:00:00pages
297-302issue
7eissn
0025-7753issn
1578-8989pii
S0025-7753(16)30633-9journal_volume
148pub_type
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