Abstract：
BACKGROUND:To establish the early risk of multiple sclerosis (MS) following isolated demyelinating syndromes. PATIENTS AND METHOD:36 patients with optic neuritis, 24 with brainstem syndromes, 27 with spinal cord syndromes and 8 patients with a poliregional syndrome were included in a prospective protocol: including clinical data, immunological determinations, oligoclonal bands, visual, somestesic and brainstem evoked potentials and a magnetic resonance imaging (MRI) study. RESULTS:MRI showed the presence of signal abnormalities in 70% of the patients. The conversion rate (CR) was 18.5%. In patients with a normal MRI, CR was 4% compared to 26% in patients with an abnormal MRI (p = 0.05). CONCLUSIONS:The early conversion rate to MS is significantly increased when MRI is abnormal.
journal_name
Med Clin (Barc)journal_title
Medicina clinicaauthors
Tintoré M,Rovira A,Hernández D,Río J,Marzo ME,Montalban Xkeywords:
subject
Has Abstractpub_date
1999-05-22 00:00:00pages
693-4issue
18eissn
0025-7753issn
1578-8989journal_volume
112pub_type
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