[Current controversies in glycemic control targets. What do the results of the latest clinical trials tell us about the approach to type 2 diabetes mellitus?].

abstract：:The ANESCAT 2003 survey has provided reliable information on all practices within the specialty of anesthesiology in a community comprising 6.7 million inhabitants (namely Catalonia, Spain). In a situation in which official statistics are lacking, the findings allow us to make predictions and plan the clinical and org...

journal_title：Medicina clinica

authors： Canet J,Gomar C,Castillo J,Villalonga A,Sabaté S,Hervàs C

更新日期：2006-05-24 00:00:00

abstract：:The serum levels of cholesterol bound to high density lipoproteins (HDL-C) were determined by the heparin-manganese chloride precipitation method in 306 subjects, 182 male with ages ranging from 11 to 81 years, and 124 female with ages ranging from 7 to 78 years. Twenty six subjects belonged to a lacto-vegetarian comm...

journal_title：Medicina clinica

authors： Masdeu S,Nubiola AR,Masana L,Ras MR,Chacón P,Ramos F,Rubiés-Prat J

更新日期：1981-03-25 00:00:00

abstract：BACKGROUND:To relate the renal hemodynamic changes, as assessed by Doppler ultrasonography,with the development of ascites, renal function, and endogenous vasoactive systems in patients with liver cirrhosis. PATIENTS AND METHODS:60 cirrhotic patients were studied prospectively, 31 of these compensated and 29 with asci...

journal_title：Medicina clinica

authors： Rendón Unceta P,Macías Rodríguez MA,Guillén Mariscal P,Tejada Cabrera M,Martínez Sierra MC,Martín Herrera L

更新日期：2001-04-28 00:00:00

abstract：BACKGROUND/OBJECTIVES:To assess the adherence to reporting confidence intervals (CI) for measures of association in multivariable regression models (MRM) in articles with observational design indexed in MEDLINE. MATERIAL AND METHODS:A literature search was conducted using the MEDLINE bibliographic database to obtain a...

journal_title：Medicina clinica

authors： González-Marrón A,Real J,Forné C,Roso-Llorach A,Navarrete-Muñoz EM,Martínez-Sánchez JM

更新日期：2019-09-27 00:00:00

abstract：BACKGROUND AND OBJECTIVE:To assess the value of rituximab in systemic autoimmune diseases which are refractory to others treatments. PATIENTS AND METHOD:Prospective study on 12 patients -7 with systemic lupus erythematosus (SLE), 4 with Wegener's granulomatosis (WG), and 1 with overlapping connective disease and autoi...

journal_title：Medicina clinica

authors： García Hernández FJ,Ocaña Medina C,González León R,Garrido Rasco R,Colorado Bonilla R,Castillo Palma MJ,Sánchez Román J

更新日期：2007-03-31 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Sense of Coherence (SOC) is a construct relating to coping strategies in the face of traumatic events. SOC is defined as a personal disposition towards perceiving life experiences as understandable, manageable and meaningful. The construct has shown itself to be a predictor of self-reported and...

journal_title：Medicina clinica

authors： Virués-Ortega J,Martínez-Martín P,Del Barrio JL,Lozano LM,Grupo Español de Estudios Epidemiológicos sobre Envejecimiento.

更新日期：2007-04-07 00:00:00

abstract：BACKGROUND AND OBJECTIVE:To evaluate the distribution of clinical, electrophysiological and biological variables, and their relationship with the CSF hypocretin-1 levels, in patients with central hypersomnias diagnosed as narcolepsy-cataplexy (NC), narcolepsy without cataplexy (NnC) and idiopathic hypersomnia (IH) base...

journal_title：Medicina clinica

authors： Martínez-Rodríguez JE,Iranzo A,Casamitjana R,Graus F,Santamaria J

更新日期：2007-03-17 00:00:00

abstract：BACKGROUND:Anal intraepithelial neoplasia is considered a precursor lesion of anal squamous carcinoma. The population with increased risk of this conditions are immunocompromised individuals, especially HIV-infected, with anal sex practices. The aim of this study was to describe the sexual habits of patients who were s...

journal_title：Medicina clinica

authors： Padilla-España L,Repiso-Jiménez JB,Frieyro-Elicegui M,Rivas-Ruiz F,Robles L,de Troya M

更新日期：2014-02-20 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The optimal treatment of aggressive non-Hodgkin lymphoma (NHL) in elderly patients remains controversial. We aimed to evaluate the impact of age and use of anthracyclines. PATIENTS AND METHOD:Retrospective analysis of patients with aggressive NHL aged over 70 years old. RESULTS:One hundred an...

journal_title：Medicina clinica

authors： Ancochea Á,Salar A,García-Pallarols F,Gimeno E,Fernández-Rodriguez C,Sánchez-González B

更新日期：2015-06-22 00:00:00

abstract：BACKGROUND AND OBJECTIVES:To establish the factors associated with the presence of non-alcoholic fatty liver disease (NAFLD) and evaluate the influence of each component constituting the metabolic syndrome (MS) and the risk of developing NAFLD. PATIENTS AND METHODS:We performed a multicenter, population-based, observa...

journal_title：Medicina clinica

authors： Caballería L,Arteaga I,Pera G,Rodríguez L,Alumà A,Auladell MA,Torán P

更新日期：2013-09-21 00:00:00

abstract：:Difficulties derived from the big complexity of the human genome (because of the great amount of genes) and difficulties at the time of performing a correct molecular diagnosis have led to the utilization of advanced technologies such as DNA arrays. By this technique, it is possible to analyze in a single experiment g...

journal_title：Medicina clinica

authors： Sáenz A,López de Munain A

更新日期：2008-04-12 00:00:00

abstract：BACKGROUND AND OBJECTIVE:After the good results obtained by the Société Française d'Oncologie Pédiatrique (SFOP) regarding the pediatric B-type non-Hodgkin's (Burkitt and large B-cell) lymphoma and L3 leukemia, the Sociedad Española de Hematología y Oncología Pediátricas (SHOP) decided to use the same treatment protoco...

journal_title：Medicina clinica

authors： Forns M,Javier G,Estella J,Fernández-Delgado R,Gallego S,García-Miguel P,Indiano JM,Navajas A,Pardo N,en representación del grupo SHOP de las Sociedades Españolas de Hematología (SEHP) y Oncología Pediátricas (SEOP).

更新日期：2007-05-05 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Our objective was to assess the activity of thiopurine methyltransferase (TPMT) in a very large number of Spanish patients with inflammatory bowel disease (IBD), to evaluate the influence of several variables (including azathioprine or 6-mercaptopurine) on that activity, and to know the proport...

journal_title：Medicina clinica

authors： Gisbert JP,Gomollón F,Cara C,Luna M,González-Lama Y,Pajares JM,Maté J,Guijarro LG

更新日期：2005-09-10 00:00:00

abstract：BACKGROUND AND OBJECTIVE:We decided to assess the overall prevalence of exposure to environmental tobacco smoke (ETS) both in general and according to the settings of exposure (home, workplace and leisure time). SUBJECTS AND METHOD:We analyzed cross-sectional data of ETS exposure in 1,059 non-smokers included in the C...

journal_title：Medicina clinica

authors： Twose J,Schiaffino A,García M,Martí M,Fernández E,Investigadores del Estudio de Seguimiento de la Encuesta de Salud de Cornellà (ES-ESC).

更新日期：2004-10-16 00:00:00

abstract：BACKGROUND:For biomedical research findings to contribute toward health gains they must reach clinicians. Academic journals have historically been considered important information sources. Birken and Parkin found seven journals to most consistently contain the best pediatric evidence and, of these seven, four were gene...

journal_title：Medicina clinica

authors： Jones TH,Hanney S,Buxton MJ

更新日期：2008-12-01 00:00:00

abstract：BASIS AND OBJECTIVE:Hepatic steatosis, also known as non-alcoholic fatty liver (NAFL), is the most frequent liver disease in obese children. Due to an increase in infantile obesity, it is experiencing a significant increment in incidence. Our objetives are: Estimate the prevalence of NAFL in children with excess weight...

journal_title：Medicina clinica

authors： Guijarro de Armas MG,Monereo Megías S,Navea Aguilera C,Merino Viveros M,Vega Piñero MB

更新日期：2015-01-20 00:00:00

abstract：BACKGROUND AND OBJECTIVE:There is a bidirectional association between neoplasia and venous thromboembolism (VTE). However, whether this association has an impact in tumor recurrence is unknown. The aim of the study is to assess the incidence of cancer recurrence after diagnosis of VTE and determine if VTE could be a ma...

journal_title：Medicina clinica

authors： Blanch Alerany M,Calvo Campos M,Romera Villegas A,Pérez-Piqueras Gómez A,Riera Batalla S,Cairols Castellote MA

更新日期：2009-10-17 00:00:00

abstract：:To evaluate the clinical and microbiological features of infective endocarditis in patients with cirrhosis we compared 18 episodes of endocarditis in these patients with a control group of patients without liver disease. In 61% of patients with cirrhosis the origin of infection was unknown. Four patients developed end...

journal_title：Medicina clinica

authors： Otones J,Fernández Clúa MA,Castrillo JM,Fernández Guerrero ML

更新日期：1989-11-11 00:00:00

abstract：BACKGROUND AND OBJECTIVE:This study estimates smoking-attributable mortality in Spain in 2006. POPULATION AND METHOD:Source data included 1) smoking prevalence in Spain; 2) deaths occurred in Spain; and 3) relative risks of mortality by tobacco-caused diseases drawn from the Cancer Prevention Study II. All data corres...

journal_title：Medicina clinica

authors： Banegas JR,Díez-Gañán L,Bañuelos-Marco B,González-Enríquez J,Villar-Álvarez F,Martín-Moreno JM,Córdoba-García R,Pérez-Trullén A,Jiménez-Ruiz C

更新日期：2011-02-12 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Two different pathways for the development of tumor have been described in colorectal carcinoma: the chromosomic instability, raised by suppressor genes and proto-oncogene alterations, and the microsatellite instability (MSI), caused by alterations in DNA repairing genes. PATIENTS AND METHOD:T...

journal_title：Medicina clinica

authors： Vidaurreta M,Sanz-Casla MT,Maestro ML,Rafael S,Jiménez F,Arroyo M,Fernández C,Cerdán J

更新日期：2005-02-05 00:00:00

abstract：BACKGROUND:B-mode ultrasonography is a simple and valid method to evaluate subclinical atherosclerosis of the major superficial arteries. The aim of this study was toknow by this technique the prevalence of carotid atherosclerosisin patients with coronary disease and related factors. PATIENTS AND METHOD:In 232patients...

journal_title：Medicina clinica

authors： Fernández-Miranda C,Luis Aranda J,Paz M,Núñez V,Gómez González P,Díaz-Rubio P,Larumbe S,Teresa Gómez Izquierdo M

更新日期：2001-03-31 00:00:00

abstract：BACKGROUND:There is no detailed information on the scientific production in biomedicine from the perspective of the centers which make up the National Health Care System. Nor has any analysis on productivity by specialties compared with that of other countries of the European Community (EC) been carried out. METHODS:T...

journal_title：Medicina clinica

authors： Camí J,Fernández MT,Gómez Caridad I

更新日期：1993-12-04 00:00:00

abstract：:Community-acquired pneumonia (CAP) is an infectious respiratory disease with an incidence that ranges from 3 to 8 cases per 1,000 inhabitants per year. This incidence increases with age and comorbidities. Forty per cent of CAP patients require hospitalization and around 10% of these patients are admitted in an Intensi...

journal_title：Medicina clinica

authors： Torres A,Barberán J,Falguera M,Menéndez R,Molina J,Olaechea P,Rodríguez A,Grupo de la Guía Multidisciplinar para el Manejo de la Neumonía Adquirida en la Comunidad.

更新日期：2013-03-02 00:00:00

abstract：BACKGROUND:Incidence analysis of tuberculosis in a series of 562 patients with chronic myeloproliferative syndrome (CMPS). 344 had chronic myelocytic leukemia, 91 polycythemia vera, 70 idiopathic myelofibrosis and 57 essential thrombocythemia. METHODS:The association between CMPS and tuberculosis was evaluated with th...

journal_title：Medicina clinica

authors： Tassies D,Cervantes F,Nicolás JM,Feliu E,Soriano E,Rozman C

更新日期：1991-03-09 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Burden of disease (DALYs) can help define health priorities. Our objective was to assess DALYs of those illnesses most important in Spanish children and teenagers. MATERIAL AND METHOD:We calculated DALYs components (YLL, YLD) by age groups and sex. Sources used were Spanish mortality data and ...

journal_title：Medicina clinica

authors： Cortés García M,Pereira Candel J,Peña-Rey Lorenzo I,Gènova Maleras R,Amela Heras C

更新日期：2004-03-20 00:00:00

abstract：BACKGROUND:Viral replication is one of the determining factors of the natural history of infection by the hepatitis B virus (HBV). The clinical significance of the viremia and the DNA-HBV findings in mononuclear cells was therefore analyzed. METHODS:The epidemiologic history, liver function tests and the Knodell index...

journal_title：Medicina clinica

authors： Crespo J,Lozano JL,López-Arias MJ,Martín-Ramos L,Sánchez-Antolín G,Dueñas C,Pons Romero F

更新日期：1994-11-05 00:00:00

abstract：OBJECTIVE:To compare the occurrence of haemorrhages among the different oral anticoagulants (OAC) and to analyse factors that influence it. MATERIAL AND METHODS:Single-centre, observational, retrospective study. After studying the total population treated with OAC, patients who were treated with an OAC from July 2015 ...

journal_title：Medicina clinica

authors： Gassó Sánchez A,Real Campaña JM,Franco Sorolla JM,Povar Marco BJ,Abad Sazatornil MR

更新日期：2019-06-21 00:00:00

abstract：:Epidemiological research has consistently shown that physical activity decreases the risk of coronary heart disease, hypertension and stroke. The finding that a low level of physical activity is a major determinant of the growing epidemics of obesity is also firm and consistent. The direct association existing between...

journal_title：Medicina clinica

authors： Varo Cenarruzabeitia JJ,Martínez Hernández JA,Martínez-González MA

更新日期：2003-11-15 00:00:00

abstract：BACKGROUND AND OBJECTIVE:We aimed to evaluate the prognostic impact of the degree and time-point of arterial recanalization during the first 24h after tPA administration in patients with acute middle cerebral artery (MCA) occlusions. PATIENTS AND METHOD:We prospectively studied consecutive ischemic stroke patients tre...

journal_title：Medicina clinica

authors： Dorado L,Arenillas JF,Millán M,Pérez De La Ossa N,Guerrero C,Dávalos A

更新日期：2009-05-02 00:00:00

abstract：:A group of 32 patients with disseminated breast cancer were submitted to polychemotherapy following Cooper's protocol. Vincristine, cyclophosphamide, 5-fluorouracil, and prednisone were administered. The fifth drug used by Cooper, methotrexate, was not included in the therapy program because of difficulties in obtaini...

journal_title：Medicina clinica

authors： Estapé J,Millá A,Prats M,Herranz M,Visa J

更新日期：1979-08-15 00:00:00