Abstract:
:Community-acquired pneumonia (CAP) is an infectious respiratory disease with an incidence that ranges from 3 to 8 cases per 1,000 inhabitants per year. This incidence increases with age and comorbidities. Forty per cent of CAP patients require hospitalization and around 10% of these patients are admitted in an Intensive Care Unit (ICU). Several studies have suggested that the implementation of clinical guidelines has a positive impact in the outcome of patients including mortality and length of stay. The more recent and used guidelines are those from Infectious Diseases Society of America/American Thoracic Society, published in 2007, the 2009 from the British Thoracic Society, and that from the European Respiratory Society/European Society of Clinical Microbiology and Infectious Diseases, published in 2010. In Spain, the most recently released guideline is the Sociedad Española de Neumología y Cirugía Torácica-2011 guideline. The present guidelines GNAC are designed to be used by the majority of health-care professionals that can participate in the care of CAP patients including diagnosis, decision of hospital and ICU admission, treatment and prevention. The Centro Cochrane Iberoamericano (CCIB) has participated in summarizing the previous guidelines and in the bibliography search. For each one of the following sections the panel of experts has developed a table with recommendations classified according to its evidence, strength and practical applicability using the Grading of Recommendations of Assessment Development and Evaluations (GRADE) system: 1. Epidemiology, microbiological etiology and antibiotic resistances.2. Clinical and microbiological diagnosis.3. Prognostic scales and decision of hospital admission.4. ICU admission criteria. 5. Empirical and definitive antibiotic treatment.6. Treatment failure. 7. Prevention.
journal_name
Med Clin (Barc)journal_title
Medicina clinicaauthors
Torres A,Barberán J,Falguera M,Menéndez R,Molina J,Olaechea P,Rodríguez A,Grupo de la Guía Multidisciplinar para el Manejo de la Neumonía Adquirida en la Comunidad.doi
10.1016/j.medcli.2012.09.034subject
Has Abstractpub_date
2013-03-02 00:00:00pages
223.e1-223.e19issue
5eissn
0025-7753issn
1578-8989pii
S0025-7753(12)00855-Xjournal_volume
140pub_type
共识发展会议,杂志文章,实务指引相关文献
MEDICINA CLINICA文献大全abstract:BACKGROUND AND OBJECTIVE:Twin and family studies support large genetic influences on variability in body mass index (BMI), with heritability estimates ranging from 47% to over 90%. Our objective was to study the relative contributions of genetics and environment to BMI, evaluating sex differences, in an adolescent twin...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2014.05.039
更新日期:2015-08-21 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The aim of the study was to assess the effect of adding spironolactone to hypertensive resistant (HTR) patients and characterize those who respond effectively. PATIENTS AND METHOD:Observational retrospective study on outpatients with HTR (being treated with at least 3 drugs at full doses, one ...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1157/13126215
更新日期:2008-10-04 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The association between the presence of the allele APOE*epsilon4 (apolipoprotein E) and sporadic Alzheimer disease (AD) has been long established. However, the possible influence of other genetic factors is still under debate. This study investigated the role of the a 1-antichymotrypsin (ACT) g...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/s0025-7753(04)74479-6
更新日期:2004-09-04 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The use of complementary and alternative medicine (CAM) is increasing in last years. Studies performed out of Spain have reported rates of CAM use of 40-50% among IBD patients. There are no available data on drug abuse among IBD patients. The aims of our study were to evaluate the rate and asso...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1157/13097468
更新日期:2007-01-20 00:00:00
abstract:BACKGROUND:Elevated blood urea nitrogen to serum albumin (BUN/ALB) ratio had been identified as an independent risk factor related to mortality in community-acquired and hospital-acquired pneumonia. This study aimed to investigate whether this clinical index can predict the clinical outcomes of E. coli bacteraemia. MA...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2020.06.060
更新日期:2020-10-12 00:00:00
abstract:BACKGROUND AND OBJECTIVE:We aimed to know the prevalence of classical cardiovascular risk factors, hyperinsulinism, insulin resistance and metabolic syndrome (MS) in a population with coronary heart disease (CHD) as compared with a population without personal or familial history of cardiovascular risk factors. SUBJECT...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/s0025-7753(03)73907-4
更新日期:2003-07-12 00:00:00
abstract::Highly malignant non-Hodgkin lymphomas (HM-NHL) may sometimes develop clinical features simulating an epithelial carcinoma with metastatic dissemination. Conventional histopathological study may be insufficient to differentiate between both conditions. Two patients with HM-NHL are reported with a rapid general deterio...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1989-03-11 00:00:00
abstract::Fosfosal or 2-phosphonoxybenzoic acid is a new analgesic drug, whose analgesic activity and side effects have been determined in a double blind clinical study in comparison with placebo. The study has been done with 60 outpatients, of both sexes, which suffered musculoskeletal and arthritic pains. Patients were treate...
journal_title:Medicina clinica
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1981-01-10 00:00:00
abstract::The use of physical and pharmacological restraint is controversial but is currently accepted as inevitable. It is indicated for controlling behavioral disorders and psychomotor agitation that put patients and third parties at risk. Its indication should be medical, and we should opt for the least restrictive measure. ...
journal_title:Medicina clinica
pub_type: 杂志文章,评审
doi:10.1016/S0025-7753(14)70068-5
更新日期:2014-03-01 00:00:00
abstract::In the present article we describe the activity of the admissions service on the day of the terrorist attacks, 11 March, 2004. Firstly, we try to describe the objectives and lines of intervention that we believe should be covered by our service. Subsequently, we describe how we organized ourselves into teams in order ...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1157/13072650
更新日期:2005-03-01 00:00:00
abstract::The case of a 74-year-old woman with a carotid-cavernous fistula is reported. She was admitted to hospital with oliguria and generalized edema. After improvement of the edematous condition she suddenly presented intense, pulsatile, frontal cephalea. It was more intense on the right side and was accompanied by nausea a...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1979-03-25 00:00:00
abstract:BACKGROUND AND OBJECTIVE:To study the effect of clinical and demographic variables on mortality in patients with probable Alzheimer's disease treated with the cholinesterase inhibitor galantamine. PATIENTS AND METHOD:This retrospective cohort study reviewed 172 medical records, gathering information such as demographi...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1157/13091012
更新日期:2006-07-08 00:00:00
abstract::In the present study, clinical, epidemiological and management factors influencing the appropriateness of the 1076 admissions to a general Internal Medicine Section during one year are evaluated. 184 admissions (17%) corresponded to patients who did not meet the AEP (Appropriateness Evaluation Protocol) criteria for a...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1990-03-03 00:00:00
abstract::Reduction in the risk of cardiovascular complications through modification of lipids is currently focused on lowering low density lipoproteins-cholesterol, with statins being the preferred drugs. New agents, under research, such as antibodies neutralizing PCSK9, will have a special place for the management of patients...
journal_title:Medicina clinica
pub_type: 杂志文章,评审
doi:10.1016/j.medcli.2013.04.026
更新日期:2014-04-07 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Leptin is an hormone resulting from the obesity gene. Their actions could be important in the pathogenesis of the osteoporosis. The aim of this study is to analyse the influence of tobacco on serum leptin levels, and its relationship with bone mineral density (BMD) and steroid hormones. SUBJEC...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1157/13094819
更新日期:2006-11-04 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The plasma protein leakage produced in the bronchial mucose of patients with acute asthma might be associated to the quickness of the onset exacerbation. The aim of this study was to study this association. PATIENTS AND METHOD:22 patients with acute asthma were recruited, and the magnitude of ...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1157/13093055
更新日期:2006-09-30 00:00:00
abstract:BACKGROUND AND OBJECTIVE:To assess the safety and efficacy of insulin analogues versus human insulin in pregnant women with pregestational diabetes. PATIENTS AND METHODS:We collected data on pregnant women with type 1 or type 2 diabetes who were attended at the Diabetes and Pregnancy Unit between January 1998 and Apri...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2010.11.021
更新日期:2011-11-19 00:00:00
abstract:BACKGROUND:A low folic acid (FA) intake may increase the risk of neural tube defects (NTD). We estimated the proportion of women with a FA intake < 400 micrograms/day, at the Valencian Region, exploring those factors associated with a FA intake < 400 micrograms/day. SUBJECTS AND METHOD:Daily FA intake was estimated fo...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/s0025-7753(00)71316-9
更新日期:2000-03-25 00:00:00
abstract::The hepatitis E virus is an RNA virus with 4 genotypes. Genotypes 1 and 2 only affect humans and produce epidemic acute hepatitis in endemic regions (Asia and Africa). Genotypes 3 and 4 are considered a zoonosis and produce episodic acute hepatitis in non-endemic areas (America and Europe). However, in the last 3 year...
journal_title:Medicina clinica
pub_type: 杂志文章,评审
doi:10.1016/j.medcli.2011.02.003
更新日期:2012-02-04 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Hypertension is highly prevalent in the very elderly. We studied control rates of hypertension according to clinic blood pressure (BP) and ambulatory BP monitoring (ABPM) in treated hypertensives aged > or =80 years. PATIENTS AND METHOD:Data came from the Spanish Society of Hypertension ABPM R...
journal_title:Medicina clinica
pub_type: 杂志文章,多中心研究
doi:10.1016/j.medcli.2009.04.056
更新日期:2009-11-28 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Fabry disease is a hereditary disorder. Clinical manifestations are multisystemic. The majority of the patients remain undiagnosed until late in life, when alterations could be irreversible. Early detection of cardiac symptoms is of major interest in Fabry's disease (FD) in order to gain acces...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2009.11.044
更新日期:2010-09-04 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The PROCES (Programa de Reanimació Cardiopulmonar Orientat a Centres d'Ensenyament Secundari) program is aimed at teaching basic cardiopulmonary resuscitation (b-CPR) to teenagers within high school. Our aim was to analyze the results obtained from the pilot program. SUBJECTS AND METHOD:PROCES...
journal_title:Medicina clinica
pub_type: 杂志文章,多中心研究
doi:10.1157/13070434
更新日期:2005-01-15 00:00:00
abstract:BACKGROUND AND OBJECTIVE:To evaluate the distribution of clinical, electrophysiological and biological variables, and their relationship with the CSF hypocretin-1 levels, in patients with central hypersomnias diagnosed as narcolepsy-cataplexy (NC), narcolepsy without cataplexy (NnC) and idiopathic hypersomnia (IH) base...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1157/13099970
更新日期:2007-03-17 00:00:00
abstract:BACKGROUND:Viral replication is one of the determining factors of the natural history of infection by the hepatitis B virus (HBV). The clinical significance of the viremia and the DNA-HBV findings in mononuclear cells was therefore analyzed. METHODS:The epidemiologic history, liver function tests and the Knodell index...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1994-11-05 00:00:00
abstract::Transfer factor (TF) consists of messenger peptides produced by activated T lymphocytes as part of cellular immunity, and it acts in virgin lymphocytes through TF inducers, suppressors and specific antigens. TF is not immunogenic because it is not species-specific, since it contains a consensus sequence of amino acids...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2010.05.002
更新日期:2011-09-10 00:00:00
abstract:BACKGROUND:Determinants associated with risk behaviours are evaluated in a known HIV-infected population not belonging to the great metropolitan nuclei. PATIENTS AND METHODS:110 unselected HIV+ patients were interviewed, including 77 variables. Their association with sharing needles, and unprotected sex is analysed. ...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1999-04-24 00:00:00
abstract:BACKGROUND:Hyperimmunoglobulinemia D and periodic fever syndrome (HIDS) is a disorder diagnosed with low frequency, that produces a very prolonged and recurrent fever with other symptoms and analytical markers of inflammation. Its origin seems to be hereditary with a recessive autosomic pattern, but its pathogenic mech...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/s0025-7753(00)71331-5
更新日期:2000-04-01 00:00:00
abstract:BACKGROUND:Anal intraepithelial neoplasia is considered a precursor lesion of anal squamous carcinoma. The population with increased risk of this conditions are immunocompromised individuals, especially HIV-infected, with anal sex practices. The aim of this study was to describe the sexual habits of patients who were s...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2013.05.047
更新日期:2014-02-20 00:00:00
abstract:BACKGROUND AND OBJECTIVE:There is a bidirectional association between neoplasia and venous thromboembolism (VTE). However, whether this association has an impact in tumor recurrence is unknown. The aim of the study is to assess the incidence of cancer recurrence after diagnosis of VTE and determine if VTE could be a ma...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2009.04.054
更新日期:2009-10-17 00:00:00
abstract::A patient is reported with meningoencephalomyelitis with polyradiculitis caused by Borrelia burgdorferi infection. Neurological features developed without previously known tick bite nor the characteristic skin lesion, chronic migratory erythema (CME). The vector of the disease (the tick Ixodes ricinus) exists in Spain...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1989-09-09 00:00:00