Abstract:
:Highly malignant non-Hodgkin lymphomas (HM-NHL) may sometimes develop clinical features simulating an epithelial carcinoma with metastatic dissemination. Conventional histopathological study may be insufficient to differentiate between both conditions. Two patients with HM-NHL are reported with a rapid general deterioration; one of them had osteolysis and hypercalcemia. In both cases a diffuse bone marrow infiltration by large sized cells with blastic appearance was found. The initial suspected diagnosis was occult epithelial neoplasia with metastatic dissemination. The morphological study with optic microscopy and the ultrastructural analysis did not establish the origin of these cells. The definitive diagnosis was obtained by immunohistochemical techniques. In both cases, the cells were positive for the CD 45 (common leukocyte antigen) monoclonal antibody (MoAb), and for several MoAbs of lymphoid B differentiation. In one of them, the B lymphoid lineage was confirmed by monoclonal reordering of the gene that synthetises the immunoglobulin heavy chain.
journal_name
Med Clin (Barc)journal_title
Medicina clinicaauthors
Plaza V,Urbano Ispizua A,Paz MA,Martos JA,Feliu E,Campo E,Matutes E,Martínez Orozco F,Rozman Csubject
Has Abstractpub_date
1989-03-11 00:00:00pages
344-6issue
9eissn
0025-7753issn
1578-8989journal_volume
92pub_type
杂志文章相关文献
MEDICINA CLINICA文献大全abstract:BACKGROUND AND OBJECTIVE:More information is needed on hypertension control in clinical practice, which includes taking at least two blood pressure (BP) readings and taking into account surgery times and previous antihypertensive drug intake. Our study aimed to assess the optimum degree of BP control in a broad sample ...
journal_title:Medicina clinica
pub_type: 杂志文章,多中心研究
doi:10.1016/s0025-7753(04)74183-4
更新日期:2004-02-14 00:00:00
abstract:BACKGROUND AND AIMS:It has been recently shown that psychiatric disorders are associated with obesity. However this association has not been studied in overweight/obese patients at a hospital setting in our country. PATIENTS AND METHODS:We have studied 333 consecutive patients who were referred to our hospital outpati...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1157/13115025
更新日期:2008-01-26 00:00:00
abstract:BACKGROUND AND OBJECTIVE:To assess the cessation and relapse rates of smoking, and analyze the associated variables in a 12-month follow-up study at a smoking cessation unit. SUBJECTS AND METHOD:Patients from the Area de Salud 19 of the Conselleria de Sanitat of the Generalitat Valenciana, coming to a smoking cessatio...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1157/13087715
更新日期:2006-04-29 00:00:00
abstract::Molecular techniques have allowed the identification of new viruses in a number of patients with cryptogenic hepatitis. Whether they are clinically inapparent or true hepatitis agents remains unknown for some of them. Latest described viruses include GBV, TTV and SENV. However, based on the limited data available, the...
journal_title:Medicina clinica
pub_type: 杂志文章,评审
doi:10.1016/s0025-7753(04)74301-8
更新日期:2004-04-17 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Although constipation affects quality of life, questionnaires hardly exist for its evaluation. We aimed to develop and validate a questionnaire able to measure the quality of life in patients with constipation. PATIENTS AND METHOD:A Spanish multicenter study was performed in 2 stages: a) quest...
journal_title:Medicina clinica
pub_type: 杂志文章,多中心研究
doi:10.1016/s0025-7753(08)72285-1
更新日期:2008-09-27 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Although smoking habit is a well-known cardiovascular risk factor, it has been described that smokers admitted because of myocardial infarction have better prognosis than non smoker patients, which is known as "the smoking paradox". The purpose of our work is to investigate whether this phenome...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2010.01.039
更新日期:2011-02-19 00:00:00
abstract::A group of 32 patients with disseminated breast cancer were submitted to polychemotherapy following Cooper's protocol. Vincristine, cyclophosphamide, 5-fluorouracil, and prednisone were administered. The fifth drug used by Cooper, methotrexate, was not included in the therapy program because of difficulties in obtaini...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1979-08-15 00:00:00
abstract:BACKGROUND AND OBJECTIVE:To evaluate the adherence to the recommendations in clinical practice performed by the Therapeutic Positioning Report (TPR) of the Spanish Agency of Medicines and Sanitary Products about the treatment with oral anticoagulants in patients aged≥75 years old with nonvalvular atrial fibrillation (N...
journal_title:Medicina clinica
pub_type: 杂志文章,多中心研究
doi:10.1016/j.medcli.2017.07.025
更新日期:2018-07-13 00:00:00
abstract::A patient is reported with meningoencephalomyelitis with polyradiculitis caused by Borrelia burgdorferi infection. Neurological features developed without previously known tick bite nor the characteristic skin lesion, chronic migratory erythema (CME). The vector of the disease (the tick Ixodes ricinus) exists in Spain...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1989-09-09 00:00:00
abstract:BACKGROUND:The aim of the present was to study the cytohistology of the bone marrow in intravenous drug addicts (IVDA) and to analyze the possible differences according to the period of drug addiction. METHODS:A prospective study was performed in 60 IVDA patients previously untreated and distributed into three groups:...
journal_title:Medicina clinica
pub_type: 临床试验,杂志文章
doi:
更新日期:1995-01-28 00:00:00
abstract::A case of rapidly progressive glomerular disease with 100% of epithelial crescents completely enveloping each glomerulus, prolonged anuria and renal failure requiring dialysis. There were no indications of either streptococcal etiology or systemic disease. Improvement in renal function in response to plasmapheresis an...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1981-06-10 00:00:00
abstract:BACKGROUND:To review the clinical findings of pancreatic tuberculosis and to establish a differential diagnosis with pancreatic tumours. PATIENTS AND METHODS:To describe three cases of pancreatic tuberculosis diagnosed in a 850 bed teaching hospital during the last two years. RESULTS:In the three case the imaging pro...
journal_title:Medicina clinica
pub_type: 杂志文章,评审
doi:10.1016/s0025-7753(00)71592-2
更新日期:2000-10-14 00:00:00
abstract:BACKGROUND:Recent studies have suggested that women with ischemic heart disease receive lesser therapeutic care than males. The aim of this study was to verify the hypothesis that sex is an independent predictive factor in therapeutic care upon admission in patients with acute myocardial infarction. METHODS:Secondary ...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1994-03-19 00:00:00
abstract::Bacterial vaginosis is a widely spread health problem with multiple connotations. It has been the subject of many studies and work during decades and it still remains a polemic entity, with contradictory finding. The polymicrobian etiology, unsolved epidemiology, obstetrico-gynecological complications and high recurre...
journal_title:Medicina clinica
pub_type: 杂志文章,评审
doi:10.1016/j.medcli.2008.11.043
更新日期:2009-11-28 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The description of different forms of PSA has opened a new strategy in the diagnosis of prostate cancer. The measurement of the ratio between free PSA and PSA in the group of patients with a PSA level between 4 and 10 ng/ml decreases the number of negative biopsies. The aim of our study was to ...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/s0025-7753(04)75311-7
更新日期:2004-02-28 00:00:00
abstract::Osteoarthritis and osteoporosis are both common conditions in the elderly but their association has long remained obscure. Recently published studies show that patients with osteoarthritis have higher bone mass but no corresponding decrease in fracture risk. This has been proposed to be due to an increased rate of fal...
journal_title:Medicina clinica
pub_type: 杂志文章,评审
doi:10.1016/j.medcli.2013.01.036
更新日期:2013-09-07 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Two different pathways for the development of tumor have been described in colorectal carcinoma: the chromosomic instability, raised by suppressor genes and proto-oncogene alterations, and the microsatellite instability (MSI), caused by alterations in DNA repairing genes. PATIENTS AND METHOD:T...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1157/13071004
更新日期:2005-02-05 00:00:00
abstract:BACKGROUND:Description of measures of secondary prevention and of health related quality of life one year after the intervention in patients undergoing coronary artery bypass surgery. PATIENTS AND METHOD:One year follow up prospective study in patients undergoing first coronary bypass surgery without associated proced...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/s0025-7753(01)71785-x
更新日期:2001-02-24 00:00:00
abstract::Since its inception in 2006, the Alliance for Patient Safety in Catalonia has played a major role in promoting and shaping a series of projects related to the strategy of the Ministry of Health, Social Services and Equality, for improving patient safety. One such project was the creation of functional units or committ...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2014.07.011
更新日期:2014-07-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The association between the presence of the allele APOE*epsilon4 (apolipoprotein E) and sporadic Alzheimer disease (AD) has been long established. However, the possible influence of other genetic factors is still under debate. This study investigated the role of the a 1-antichymotrypsin (ACT) g...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/s0025-7753(04)74479-6
更新日期:2004-09-04 00:00:00
abstract::Three representative cases of the clinical heterogeneity of Castleman's disease are presented: one localized form with hialine vascular histology (HV) and 2 multicentric forms corresponding to the plasmocellular variety (PC). The asymptomatic patient with HV was treated with surgical resection of one tumor. The 2 pati...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1994-11-12 00:00:00
abstract:BACKGROUND:We describe the characteristics of people with a recent diagnosis of HIV infection. PATIENTS AND METHOD:Series of 126 new cases of HIV infection diagnosed in an infectious diseases Service. RESULTS:Sexual transmission was the commonest form of infection (74%). Fifteen percent of individuals were aged over ...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/s0025-7753(01)72211-7
更新日期:2001-11-24 00:00:00
abstract:BACKGROUND:The purpose of this study was to know the concordance of diagnosis between emergency rooms amd hospitalization wards and to analyze the mistake index, the epidemiological characteristics and the main reasons for the mistakes. PATIENTS AND METHOD:We analyzed hospitalized patients and used a three-level conco...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/s0025-7753(02)73485-4
更新日期:2002-10-26 00:00:00
abstract::We report the case of a female aged 67 years suffering a Waldenström's macroglobulinemia which began with arthritis at the knee and pleural effusion. In both locations the anatomopathological examination showed infiltration by typical lympho-plasmatic cells. Other possible etiologies such as amyloid, infection or arth...
journal_title:Medicina clinica
pub_type: 杂志文章,评审
doi:
更新日期:1990-10-27 00:00:00
abstract::The case of a dysbaric accident with occurred in a professional athlete during a national competition is herein reported. The clinical symptoms and response to treatment in a depressurization chamber in addition to CT controls should alert physicians in coastal areas in which this sport is carried out in order to take...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1995-05-20 00:00:00
abstract:BACKGROUND:In the context of the COVID-19 pandemic the risk of misdiagnosis of other causes of respiratory infection is likely. In this work we aim to describe the clinical characteristics, treatment and outcome of pneumococcal infection in COVID-19 patients. PATIENTS AND METHODS:Every COVID-19 patient presenting with...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2020.05.022
更新日期:2020-12-11 00:00:00
abstract:BACKGROUND:Myotonic dystrophy (DM) is an inherited autosomal dominant disorder. The molecular defect responsible for the disease is the expansion of a CTG triplet at the 3' end of the DM gene. We report the analysis of the gene expansion, its correlation with the clinical severity and with the phenomenon of anticipatio...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1993-03-13 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Functional assessment is especially relevant in patients with cognitive impairment (CI). The Disability Assessment for Dementia (DAD) scale assesses functional ability and its use is becoming increasingly popular. This study aims to perform the translation and cultural adaptation of the DAD sca...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2017.03.029
更新日期:2017-09-20 00:00:00
abstract::A prospective analysis was carried out to evaluate the cost-effectiveness of two alternatives for the treatment of hypo-agammaglobulinemia with intravenous immunoglobulin: the current hospital administration and the administration in the patient's home. 38 patients or relatives were surveyed about their personal or fa...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1991-01-19 00:00:00
abstract:OBJECTIVES:To analyze the results, efficacy and safety of unilateral microelectrode guided pallidotomy for the treatment of advanced Parkinson's disease, three months and one year after surgery. PATIENTS AND METHODS:23 patients with advanced Parkinson's disease (mean age 58.9 years and mean disease duration 14.4 years...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:2000-02-19 00:00:00