Abstract:
:Transfer factor (TF) consists of messenger peptides produced by activated T lymphocytes as part of cellular immunity, and it acts in virgin lymphocytes through TF inducers, suppressors and specific antigens. TF is not immunogenic because it is not species-specific, since it contains a consensus sequence of amino acids LLYAQDL/VEDN. TF extracted from leukocytes can transfer immunity from a human to another species. TF extracts are complex, containing more than 200 molecules with molecular weights ranging from 1 to 20 kDa. The antigen specific transfer factors (STF) have molecular weights between 3,5 and 5 kDa. TF is easy to prepare and well tolerated. It does not contain HL-A antigens against potential receptors and it can used as adjuvant therapy in several diseases.
journal_name
Med Clin (Barc)journal_title
Medicina clinicaauthors
Sánchez-González DJ,Sosa-Luna CA,Vásquez-Moctezuma Idoi
10.1016/j.medcli.2010.05.002subject
Has Abstractpub_date
2011-09-10 00:00:00pages
273-7issue
6eissn
0025-7753issn
1578-8989pii
S0025-7753(10)00577-4journal_volume
137pub_type
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