Abstract：
BACKGROUND:To evaluate the diagnostic power of serum myoglobin (Mgb) by latex agglutination as a marker in the first hours of acute myocardial infarction (AMI). METHODS:Two hundred forty-eight serum samples from 53 patients admitted to the Coronary Unit (CU) from the Emergency Department (ED) for suspected AMI were studied. The extractions were carried out upon admission and at 4, 8, 12, 18, 24 and 36 hours after the initiation of symptoms. Myoglobin was analyzed by radioimmunoassay (RIA) and by a semiquantitative method of latex agglutination (Rapitex), in addition to creatine kinase (CK) and MB fraction (CK-MB). Sensitivity (S), specificity (E), positive and negative predictive value (PPV) (NPV) and standard efficacy (SE) of the different markers were measured along with the correlation between RIA and latex methods for Mgb. RESULTS:For a prevalence of 83%, the latex test provided S = 81%, E = 8%, PPV = 97%, NPV = 50%, ES = 0.85; CK S = 43% (*), E = 88%, PPV = 97%, NPV = 24% (*) and ES = 0.31 (*) (* = p less than 0.01) and CK-MB S.63% (*), E = 100%, PPV = 100%, NPV = 34% (*) and ES = 0.31 (*) (* = p less than 0.05). The correlation between latex and RIA in the first 4 hours was r = 0.8243 (p less than 0.0001). On performing the 2 tests separated by 2 in the first 4, latex NPV was 100%. CONCLUSIONS:Mgb - latex is the earliest AMI indicator and has greater diagnostic strength in the first hours than CK and CK-MB. It has a good correlation with Mgb-RIA and is simple and rapid to carry out making it specially useful in Emergency Departments and Coronary Units.
journal_name
Med Clin (Barc)journal_title
Medicina clinicaauthors
Menéndez Fernández JM,Romero Tarín E,Fernández B,Fernández Coto T,del Busto Prado F,Mayordomo López J,Marín Fernández Bkeywords:
subject
Has Abstractpub_date
1992-07-04 00:00:00pages
213-7issue
6eissn
0025-7753issn
1578-8989journal_volume
99pub_type
杂志文章相关文献
MEDICINA CLINICA文献大全abstract：BACKGROUND AND OBJECTIVE:The plasma protein leakage produced in the bronchial mucose of patients with acute asthma might be associated to the quickness of the onset exacerbation. The aim of this study was to study this association. PATIENTS AND METHOD:22 patients with acute asthma were recruited, and the magnitude of ...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1157/13093055
更新日期：2006-09-30 00:00:00
abstract：BACKGROUND:"Stroke Code" is a system for the rapid identification, pre-notification and transport of acute ischemic stroke patients. The objective of this study was to evaluate the impact of delay reduction for thrombolytic therapy in these patients. SUBJECTS AND METHODS:We evaluated acute ischemic stroke patients adm...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1999-10-23 00:00:00
abstract：:Reduction in the risk of cardiovascular complications through modification of lipids is currently focused on lowering low density lipoproteins-cholesterol, with statins being the preferred drugs. New agents, under research, such as antibodies neutralizing PCSK9, will have a special place for the management of patients...
journal_title：Medicina clinica
pub_type： 杂志文章,评审
doi：10.1016/j.medcli.2013.04.026
更新日期：2014-04-07 00:00:00
abstract：:Monitoring biomedical signals obtained from a patient generates information that processed conveniently, it has to allow detecting as soon as possible changes in the predicted evolution. The systematic register of one of these biomedical signals is named a time series. In this paper, a brief introduction appears to th...
journal_title：Medicina clinica
pub_type： 杂志文章,评审
doi：10.1157/13057547
更新日期：2004-01-01 00:00:00
abstract：BACKGROUND:In this study the prescription of drugs in an outpatients geriatric population was evaluated in terms of age and body weight. METHODS:From a wide survey carried out on 500 geriatric outpatients, all the prescriptions corresponding to H-2 antagonists, digoxin, theophylline, bromazepam, diazepam, lorazepam an...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1992-03-07 00:00:00
abstract：:The aim of this article is to discuss the implications of the results obtained in the latest large-scale clinical trials designed to evaluate the effect of intensive glycemic control on the vascular complications associated with type 2 diabetes mellitus. The current scientific evidence is reviewed and the implications...
journal_title：Medicina clinica
pub_type： 杂志文章,评审
doi：10.1016/S0025-7753(10)70025-7
更新日期：2010-09-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The management of cardiac ischemic patients differs depending on their comorbidity. The Charlson Index (ChI) and its adaptations are well established and widely used tools to quantify a patient comorbidity. The aim of this study is to evaluate the influence of comorbidity quantified by the ChI ...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1157/13073218
更新日期：2005-04-02 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The aim of this study was to evaluate the ability of long-term highly active antiretroviral therapy (HAART) to fully reconstitute the immune system in children with severe AIDS. PATIENT AND METHOD:Lymphoproliferative responses (LPR) were evaluated by incorporation of [3H]-thymidine. Cytokine p...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/s0025-7753(03)73723-3
更新日期：2003-03-29 00:00:00
abstract：BACKGROUND AND OBJECTIVE:To assess the relationship between reputation of hospitals, as determined by specialists' opinion, and their scientific production. MATERIAL AND METHOD:A questionnaire was sent to a sample of members of the Spanish Societies of Cardiology, Digestive Diseases, Neurology and Otorhinolaryngology....
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1157/13089112
更新日期：2006-05-27 00:00:00
abstract：:Negative-pressure wound therapy (NPWT) is used to promote wound healing by using suction to drain excess fluid from wounds. A systematic literature review was undertaken to assess the effectiveness, safety and cost-effectiveness of NPWT for the treatment of chronic wounds. Medline, Embase, CENTRAL, CINAHL and the Coch...
journal_title：Medicina clinica
pub_type： 杂志文章,评审
doi：10.1016/j.medcli.2010.06.010
更新日期：2011-09-17 00:00:00
abstract：BACKGROUND:The empiric treatment of extrahospitalary urinary infections must keep in mind the patterns of susceptibility of the potentially causative bacteria. The consumption of antibiotics is one of the most important causes of change in the susceptibility of the bacteria. The recent introduction of fluorquinolones a...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1993-06-12 00:00:00
abstract：:The aim of this work is to show the changes observed in the health profile according to gender in 2006 with respect to 1994 of the population of Catalonia, through the comparison of data obtained in 1994 and 2006 from the Encuesta de Salud de Cataluña. The increase of the level of studies of the population has tended ...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/S0025-7753(11)70025-2
更新日期：2011-12-01 00:00:00
abstract：BACKGROUND:Increasing attention has been given to the care to elderly patients in emergency departments (ED). Moreover, few data are available about final phase of the process, that is hospital admission from ED. This study was conducted to establish appropriateness, reasons and social factors related to hospital admis...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1994-10-15 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Liver re-transplantation (re-LT) is an accepted indication for some (technical problems, primary non-function [PNF]) but not all indications, particularly recurrence of the original disease, such as hepatitis C. We aimed to determine in our center: a) the rate of survival following re-transplan...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1157/13075442
更新日期：2005-05-21 00:00:00
abstract：BACKGROUND:Hyperimmunoglobulinemia D and periodic fever syndrome (HIDS) is a disorder diagnosed with low frequency, that produces a very prolonged and recurrent fever with other symptoms and analytical markers of inflammation. Its origin seems to be hereditary with a recessive autosomic pattern, but its pathogenic mech...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/s0025-7753(00)71331-5
更新日期：2000-04-01 00:00:00
abstract：:The term cryptogenic stroke refers to a stroke for which there is no specific attributable cause after a comprehensive evaluation. However, there are differences between the diagnostic criteria of etiological classifications used in clinical practice. An improvement in diagnostic tools such advances in monitoring for ...
journal_title：Medicina clinica
pub_type： 杂志文章,评审
doi：10.1016/j.medcli.2018.01.024
更新日期：2018-08-10 00:00:00
abstract：BACKGROUND AND OBJECTIVE:We analyzed baseline and kinetic characteristics of lipid metabolism during the first month of bitherapy in patients with chronic hepatitis C genotype 1 (CHC-1). PATIENTS AND METHODS:A longitudinal, prospective study including 99 naïve CHC-1 patients with liver biopsy who were treated with bit...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/j.medcli.2013.12.016
更新日期：2015-06-22 00:00:00
abstract：BACKGROUND:Clinical observation ratifies the existence of commonly accepted erroneous beliefs (EB) in relation to sexuality. In the health care sector, reinforcing factors of these beliefs are the professionals who are not specifically trained to manage, or detect the same in addition to the variability of the criteria...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1995-11-25 00:00:00
abstract：BACKGROUND:The prognosis of sarcoidosis is difficult to predict. In general, sarcoidosis is considered as chronic when it remains active for over 2 years. The aim of this study was to analyze predictive factors in the persistence of sarcoidosis activity 2 years after diagnosis. METHODS:One hundred fifty-five patients ...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1991-12-07 00:00:00
abstract：:We present the two first Spanish cases about the endodermic heterotopia of the atrioventricular node. This is an infrequent and probably congenital lesion, with a not well known histogenesis and associated with heart blocks and sudden death, which affects women in most cases. The first observation attaches a 55 years-...
journal_title：Medicina clinica
pub_type： 杂志文章,评审
doi：
更新日期：1995-02-25 00:00:00
abstract：:Renal complications in Waldenström's macroglobulinemia (WM) are infrequent and are characterized by the presence of PAS positive amorphous hyaline deposits in the capillary lumen, infiltrated with lymphoplasmatic cells with PAS positive inclusions in the interstices and intratubular hyaline cylinders. Membranous glome...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1991-10-26 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Alcohol and drug dependent patients present a higher psychiatric comorbidity, which increases according to the number of drugs. Moreover, there are complications from the treatment and the prognosis is aggravated. We aimed to observe the differences regarding personality disorders (PD) and cogn...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1157/13120771
更新日期：2008-05-17 00:00:00
abstract：BACKGROUND AND OBJECTIVE:More information is needed on hypertension control in clinical practice, which includes taking at least two blood pressure (BP) readings and taking into account surgery times and previous antihypertensive drug intake. Our study aimed to assess the optimum degree of BP control in a broad sample ...
journal_title：Medicina clinica
pub_type： 杂志文章,多中心研究
doi：10.1016/s0025-7753(04)74183-4
更新日期：2004-02-14 00:00:00
abstract：:In the last years stem cells (SC) have generated huge expectations and have become a new hope for the development of novel cell therapies in the context of regenerative medicine. So far, the hypothetic therapeutic effects of SC, both of embryonic and adult origin, have been demonstrated only in a very few cases. Embry...
journal_title：Medicina clinica
pub_type： 杂志文章,评审
doi：10.1157/13073565
更新日期：2005-04-09 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Although health risks associated to excessive body fat increase with small increases in body weight, measurement of body fat is usually grouped in very few categories. The aim of our study was to assess whether the risk for a combined end-point including the incidence of either hypertension an...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/j.medcli.2009.02.016
更新日期：2009-05-09 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Around 75% of the population in our country will die as a consequence of chronic advanced diseases. Advanced chronic care is one of the major challenges for public health systems. This study describes the development of a tool to identify patients with advanced chronic diseases and life limited...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/j.medcli.2012.06.027
更新日期：2013-03-16 00:00:00
abstract：BACKGROUND AND OBJECTIVES:To evaluate anti-IgE (ie, omalizumab) efficacy on severe allergic asthma in order to achieve the efficacy of this treatment on severe allergic asthma progress by means of asthma control questionnaire (ACQ), asthma quality of life questionnaire (AQLQ) as well as pulmonary function (FEV1) and ph...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/j.medcli.2009.07.011
更新日期：2009-10-03 00:00:00
abstract：OBJECTIVE:To compare the occurrence of haemorrhages among the different oral anticoagulants (OAC) and to analyse factors that influence it. MATERIAL AND METHODS:Single-centre, observational, retrospective study. After studying the total population treated with OAC, patients who were treated with an OAC from July 2015 ...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/j.medcli.2018.10.006
更新日期：2019-06-21 00:00:00
abstract：:Clinical trials and prospective observational registries are useful methods to gain knowledge of vascular disease. Because the design of clinical trials is mainly based on demonstrating the efficiency of therapeutic procedures, these studies cannot be widely generalized, especially in complex multifactorial diseases s...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/S0025-7753(09)71744-0
更新日期：2009-09-01 00:00:00
abstract：:A case of primary amyloidosis in which multinucleated giant cells occurred in relation to amyloid deposits in the renal-glomerulus and in multiple other organs is reported. The ubiquity of multinucleated giant cells distinguishes the present case from those previously described in the literature. It is felt that the f...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1979-11-10 00:00:00
