[Drug administration schedules in geriatric patients].

Abstract:

BACKGROUND:In this study the prescription of drugs in an outpatients geriatric population was evaluated in terms of age and body weight. METHODS:From a wide survey carried out on 500 geriatric outpatients, all the prescriptions corresponding to H-2 antagonists, digoxin, theophylline, bromazepam, diazepam, lorazepam and triazolam were analyzed. The patients studied were of 60 or more years of age. For each drug patients were stratified into groups according to intervals of body weight with mean age of the patient being determined in each of the intervals as well as the doses received in mg/kg. RESULTS:Two hundred eighty prescriptions were analyzed with 12% corresponding to the H-2 antagonists, 29% to digoxin, 23% to theophylline and 35% to benzodiazepines. There was no significant correlation between age and the doses received. In general, the lowest body weight corresponded with a higher mean age and a marked increase in the mean dose of cimetidine, ranitidine, theophylline, bromazepam, lorazepam, and triazolam administered. There was a tendency to an adjustment in the doses of digoxin in the most elderly patients. CONCLUSIONS:The data found concerning the prescription of drugs to a geriatric outpatients population indicate that in elderly patients adjustments are not made in the doses of drugs administered according to the age and body weight of the patient. Low body weight of the elderly is a overdosage risk factor.

journal_name

Med Clin (Barc)

journal_title

Medicina clinica

authors

Lucena González ML,García Domínguez MD,Andrade Bellido RJ,Hidalgo Sánchez R,Ramírez Torres JM,Sánchez de la Cuesta F

keywords:

subject

Has Abstract

pub_date

1992-03-07 00:00:00

pages

329-32

issue

9

eissn

0025-7753

issn

1578-8989

journal_volume

98

pub_type

杂志文章
  • [Elderly patients with recurrent falls. Role of posturographic studies].

    abstract:BACKGROUND AND OBJECTIVE:Our purpose was to provide information about static and dynamic balance posturographic disorders in elderly people with recurrent falls, and to compare the results with a healthy elderly group. PATIENTS AND METHOD:We included 95 subjects: 57 patients who fell (86% women; age, 78.1 years) and 3...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1157/13071759

    authors: Lázaro M,Cuesta F,León A,Sánchez C,Feijoo R,Montiel M,Ribera JM

    更新日期:2005-02-19 00:00:00

  • [Effects of simvastatin on acute-phase protein levels after cardiac surgery].

    abstract:BACKGROUND AND OBJECTIVE:There is contradictory evidence as to whether the pleiotropic effects of statins improve morbidity/mortality rates in coronary artery bypass grafting with extracorporeal circulation, as they reduce the protein plasma levels in the acute phase. PATIENTS AND METHOD:This randomized prospective st...

    journal_title:Medicina clinica

    pub_type: 杂志文章,随机对照试验

    doi:10.1157/13121102

    authors: Tamayo E,Alonso O,Alvarez FJ,Castrodeza J,Flórez S,di Stefano S

    更新日期:2008-05-31 00:00:00

  • [Lipid profile in the hyperacute phase of ischemic stroke allows to decide cholesterol-lowering therapy].

    abstract:BACKGROUND AND OBJECTIVE:We aimed to determine whether measuring the hyperacute lipid profile helps to start a cholesterol-lowering therapy soon after an ischemic stroke. PATIENTS AND METHOD:72 ischemic stroke patients underwent lipid determinations at three times (hyperacute phase or arrival, second day and the third...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1157/13072322

    authors: Delgado Martínez P,Montaner Villalonga J,Chacón P,Purro F,Ribó M,Alvarez-Sabín J

    更新日期:2005-03-05 00:00:00

  • [Evolution of serologically confirmed cases of mumps in the Madrid community, Spain, during a period of 7 years (2000--2006)].

    abstract:BACKGROUND AND OBJECTIVE:The aim of this study was to describe the evolution of serologically confirmed cases of mumps in the Madrid Community from 2000 to 2006. PATIENTS AND METHOD:Cases with data about age, sex and with samples obtained < or = 30 days after the onset of symptoms were included. IgM determination was ...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1157/13116573

    authors: Sanz JC,de Ory F,Fernández M,Herranz N,Méndez N,Ramírez R

    更新日期:2008-03-08 00:00:00

  • [Fever of unknown origin with a prolonged course (author's transl)].

    abstract::Out of 110 cases of fever of unknown origin (FUO) that met Petersdorf and Beeson's criteria 15 patients were selected because of prolonged FUO with more than six months elapsed between admission and the final diagnosis. In this group of chronic FUO an etiological diagnosis was reached in 11 cases, distributed as follo...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Barbado Hernández FJ,Redondo C,Muñoz A,Gil A,Puig JA,Vázquez Rodríguez JJ

    更新日期:1981-05-10 00:00:00

  • [Optic neuritis, brain stem syndromes and myelitis: rapid conversion to multiple sclerosis].

    abstract:BACKGROUND:To establish the early risk of multiple sclerosis (MS) following isolated demyelinating syndromes. PATIENTS AND METHOD:36 patients with optic neuritis, 24 with brainstem syndromes, 27 with spinal cord syndromes and 8 patients with a poliregional syndrome were included in a prospective protocol: including cl...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Tintoré M,Rovira A,Hernández D,Río J,Marzo ME,Montalban X

    更新日期:1999-05-22 00:00:00

  • [High-degree malignancy non-Hodgkin's lymphoma simulating a disseminated carcinoma. Presentation of 2 cases].

    abstract::Highly malignant non-Hodgkin lymphomas (HM-NHL) may sometimes develop clinical features simulating an epithelial carcinoma with metastatic dissemination. Conventional histopathological study may be insufficient to differentiate between both conditions. Two patients with HM-NHL are reported with a rapid general deterio...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Plaza V,Urbano Ispizua A,Paz MA,Martos JA,Feliu E,Campo E,Matutes E,Martínez Orozco F,Rozman C

    更新日期:1989-03-11 00:00:00

  • [Autoinflammatory syndromes].

    abstract::Autoinflammatory syndromes are characterised by recurrent or persistent inflammation with no increase in the antibody titers or antigen-specific T lymphocytes, and absence of infection. Initially, they included the hereditary periodic fever syndromes, a group of innate immune system monogenic diseases characterised by...

    journal_title:Medicina clinica

    pub_type: 杂志文章,评审

    doi:10.1016/S0025-7753(11)70002-1

    authors: Antón J

    更新日期:2011-01-01 00:00:00

  • [Bacillary (epithelioid) angiomatosis with a nodular presentation and self-limited evolution].

    abstract::Bacillary angiomatosis (epithelioid) is a recently described clinicopathologic syndrome, principally associated to infection by the human immunodeficiency virus. The case of a patient who was seen for fever and the appearance of four painful, erythematous and indurated subcutaneous nodules on the anteroexternal face o...

    journal_title:Medicina clinica

    pub_type: 杂志文章,评审

    doi:

    authors: Teira R,López I,Zubero Z,Muñoz J,Careaga JM,Santamaría JM

    更新日期:1993-06-12 00:00:00

  • Consensus document for the use of the Polypill in the secondary prevention of cardiovascular disease.

    abstract::Cardiovascular disease is a chronic disorder which is usually already at an advanced stage when the first symptoms develop. The fact that the initial clinical presentation can be lethal or highly incapacitating emphasizes the need for primary and secondary prevention. It is estimated that the ratio of patients with go...

    journal_title:Medicina clinica

    pub_type: 共识发展会议,杂志文章

    doi:10.1016/j.medcli.2016.10.031

    authors: González-Juanatey JR,Mostaza JM,Lobos JM,Abarca B,Llisterri JL,Baron-Esquivias G,Galve E,Lidón RM,Garcia-Moll FX,Sánchez PL,Suárez C,Millán J,Pallares V,Alemán JJ,Egocheaga I

    更新日期:2017-02-09 00:00:00

  • [Reimplantation lesion in the postoperative period of lung transplantation. Incidence, predictive factors, prognosis and outcome. The Lung Transplantation Group of Vall d'Hebron University General Hospital].

    abstract:BACKGROUND:Reimplantation disease (RD) is a postoperative complication in lung transplantation. It is defined as hypoxemia (PaO2/FiO2 ratio < 150 mmHg), radiologic infiltrates and decrease of lung compliance. The aim of the study was to analyze the incidence, predictive factors, prognosis and outcome of the patients wi...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Anglès R,Tenorio L,Bravo C,Teixidor J,Rochera M,de Latorre FJ

    更新日期:1999-06-26 00:00:00

  • [Hemolytic-uremic syndrome in the adult (author's transl)].

    abstract::This article presents six cases of hemolytic-uremic syndrome, defined as the combination of acute renal insufficiency, microangiopathic hemolytic anemia, and thrombocytopenia, in six adult patients, two men and four women, between 20 and 52 years old. Three of the cases were considered idiopathic, two secondary to the...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Montoliu J,Darnell A,Torras A,Botey A,Revert L

    更新日期:1980-01-10 00:00:00

  • [Acute phase response after stroke: differences between ischemic stroke and intracerebral hemorrhage].

    abstract:BACKGROUND:To evaluate differences in the temporal profile of acute phase response (APR) between ischemic stroke (IS) and intracerebral hemorrhage (ICH). PATIENTS AND METHOD:We studied APR parameters (< 24 h and 3-5 day) in 88 consecutive patients (43 ICH and 45 IS). The increase/decrease of the parameters between bot...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/s0025-7753(01)71717-4

    authors: Montaner,Alvarez-Sabín J,Abilleira S,Molina C,Arenillas J,Codina A

    更新日期:2001-01-20 00:00:00

  • [Multidisciplinary guidelines for the management of community-acquired pneumonia].

    abstract::Community-acquired pneumonia (CAP) is an infectious respiratory disease with an incidence that ranges from 3 to 8 cases per 1,000 inhabitants per year. This incidence increases with age and comorbidities. Forty per cent of CAP patients require hospitalization and around 10% of these patients are admitted in an Intensi...

    journal_title:Medicina clinica

    pub_type: 共识发展会议,杂志文章,实务指引

    doi:10.1016/j.medcli.2012.09.034

    authors: Torres A,Barberán J,Falguera M,Menéndez R,Molina J,Olaechea P,Rodríguez A,Grupo de la Guía Multidisciplinar para el Manejo de la Neumonía Adquirida en la Comunidad.

    更新日期:2013-03-02 00:00:00

  • [Subclinical carotid atherosclerosis in patients with coronary disease].

    abstract:BACKGROUND:B-mode ultrasonography is a simple and valid method to evaluate subclinical atherosclerosis of the major superficial arteries. The aim of this study was toknow by this technique the prevalence of carotid atherosclerosisin patients with coronary disease and related factors. PATIENTS AND METHOD:In 232patients...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/s0025-7753(01)71864-7

    authors: Fernández-Miranda C,Luis Aranda J,Paz M,Núñez V,Gómez González P,Díaz-Rubio P,Larumbe S,Teresa Gómez Izquierdo M

    更新日期:2001-03-31 00:00:00

  • [Cytogenetic study of 93 myelodysplastic syndromes].

    abstract:BACKGROUND:We describe the cytogenetic results of 93 patients with myelodysplastic syndromes (MDS). The main object of this report is to analyze the prognostic value of the karyotype in patients with MDS, in relation to the evolution to acute leukemia and the survival time. PATIENTS AND METHODS:Cytogenetic studies wer...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Solé F,Woessner S,Florensa L,Pérez-Losada A,Acín P,Besses C,García-Eroles L,Sans-Sabrafen J

    更新日期:1998-01-31 00:00:00

  • [Human papillomavirus and human immunodeficiency virus infections as risk factors for cervix cancer in women prisoners].

    abstract:BACKGROUND:The identification of high risk groups for genital human papillomavirus (HPV) infection may contribute to cervical cancer prevention. The study was designed to estimate the prevalence of HPV infection and the related risk of cervical cancer among imprisoned women. PATIENTS AND METHODS:157 women were visited...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/s0025-7753(00)71472-2

    authors: de Sanjosé S,Valls I,Paz Cañadas M,Lloveras B,Quintana MJ,Shah KV,Bosch FX

    更新日期:2000-06-17 00:00:00

  • Health-related quality of life according to the main caregiver in patients with home nutritional support.

    abstract:BACKGROUND AND OBJECTIVE:We intended to know the degree of agreement between the quality of life's perception of patients with home nutritional support and that of their main caregiver in the different dimensions. We also aimed to establish the predictive ability of the health-related quality of life (HRQL) punctuation...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/s0025-7753(08)72258-9

    authors: Wanden-Berghe C,Nolasco A,Planas M,Sanz-Valero J,Rodríguez T,Cuerda C,Guardiola R,Castelló-Botia I,Grupo NADYA-SENPE.

    更新日期:2008-09-13 00:00:00

  • [Diagnosis, biomarkers and biochemical alterations in Gaucher's disease].

    abstract::Gaucher's disease (GD) is an inherited metabolic disease due to lack of activity of the enzyme betaglucocerebrosidase. The diagnosis of GD is usually performed by fluorimetric analysis of the enzyme betaglucocerebrosidase. It can also be done by measuring the activity of tandem mass spectrometry. This enzyme can be an...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/S0025-7753(11)70011-2

    authors: Gort L,Coll MJ

    更新日期:2011-09-01 00:00:00

  • [Levodopa-induced psychosis in patients with idiopathic Parkinson disease].

    abstract:BACKGROUND:To identify which clinical factors can modify the probability of the appearance of the psychotic syndromes in patients with idiopathic Parkinson's disease treated with levodopa. PATIENTS AND METHODS:214 patients were retrospectively studied to evaluate the appearance of hallucinosis, delusions or mental con...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: García-Escrig M,Bermejo Pareja F,Fernández Ponsatí JT

    更新日期:1999-02-27 00:00:00

  • Vertebral osteomyelitis: Clinical, microbiological and radiological characteristics of 116 patients.

    abstract:INTRODUCTION/OBJECTIVES:To describe the clinical, radiological and microbiological characteristics of vertebral osteomyelitis patients, analysing the factors that played a role on their outcome. PATIENTS AND METHODS:Single-centre retrospective observational study including patients diagnosed with vertebral osteomyelit...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/j.medcli.2019.12.029

    authors: Fragío Gil JJ,González Mazarío R,Salavert Lleti M,Román Ivorra JA

    更新日期:2020-10-23 00:00:00

  • [High prevalence of left ventricular hypertrophy in patients with hypertension of long course].

    abstract:BACKGROUND AND OBJECTIVE:Left ventricular hypertrophy (LVH) is the most frequent manifestation of cardiac damage in hypertension. The objective of this study was to evaluate the prevalence of LVH in hypertensive patients of long evolution at Primary Care (PC) and to describe their epidemiological profile. PATIENTS AND...

    journal_title:Medicina clinica

    pub_type: 杂志文章,多中心研究

    doi:10.1157/13106936

    authors: Fernández Villaverde JM,Maestro Saavedra FJ,Allut Vidal G,Grigorian Shamagian L,Otero-Raviña F,González-Juanatey JR,Grupo Barbanza.

    更新日期:2007-06-09 00:00:00

  • [Prevalence of bacterial vaginosis in an obstetric population of Barcelona].

    abstract:OBJECTIVES:To investigate the prevalence and risk factors of bacterial vaginosis (BV) in a pregnant population of Barcelona (Spain). MATERIAL AND METHODS:301 pregnant women controlled in the Hospital Clinic i Provincial (HCP) of Barcelona were enrolled in the study. Complete epidemiological information, and vaginal sa...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Martínez de Tejada B,Coll O,de Flores M,Hillier SL,Landers DV

    更新日期:1998-02-21 00:00:00

  • [The 4-component model of body composition].

    abstract:BACKGROUND:Given the importance of knowing the corporal composition according to the model of the four components (fat, mineral, fat free and aqueous) the same was calculated in 220 women and 130 men, considered as normal, between the ages of 15 and 49. METHODS:The corporal components were determined with double energ...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:

    authors: Rico H,Revilla M,Hernández ER,Villa LF,Alvarez del Buergo M

    更新日期:1992-03-28 00:00:00

  • [Analysis of asthma control and quality of life in severe allergic asthmatics under treatment with anti-IgE, omalizumab].

    abstract:BACKGROUND AND OBJECTIVES:To evaluate anti-IgE (ie, omalizumab) efficacy on severe allergic asthma in order to achieve the efficacy of this treatment on severe allergic asthma progress by means of asthma control questionnaire (ACQ), asthma quality of life questionnaire (AQLQ) as well as pulmonary function (FEV1) and ph...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/j.medcli.2009.07.011

    authors: Pacheco-Galván A,Hinojosa-Macías M,Hurtado-Barbudo B,González-Cervera J,Sueiro-Bendito A

    更新日期:2009-10-03 00:00:00

  • Surgical (close lateral internal sphincterotomy) versus chemical (botulinum toxin) sphincterotomy as treatment of chronic anal fissure.

    abstract:BACKGROUND AND OBJECTIVE:The aim of this prospective randomized trial was to compare the effectiveness and morbidity of surgical vs chemical sphincterotomy in the treatment of chronic anal fissure after a 3-year follow-up period. PATIENTS AND METHOD:Eighty patients with chronic anal fissure were treated either with cl...

    journal_title:Medicina clinica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1157/13074137

    authors: Arroyo Sebastián A,Pérez Vicente F,Miranda Tauler E,Sánchez Romero A,Serrano Paz P,Calpena Rico R

    更新日期:2005-04-23 00:00:00

  • [The relevance of the ankle-arm index to the reclassification of cardiovascular risk in asymptomatic hypertensive middle-aged males].

    abstract:BACKGROUND AND OBJECTIVE:The ankle-brachial index allows for the detection of subclinical cardiovascular disease and risk, by diagnosing peripheral arterial disease and arterial calcification. Asymptomatic hypertensive men, between 45-55 years and with the suspicion of low risk, could be an important population group t...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/j.medcli.2014.02.028

    authors: Oliveras V,Martín-Baranera M,Gracia M,Del Val JL,Plans M,Pujol-Moix N

    更新日期:2015-05-21 00:00:00

  • [Acute renal failure after the administration of enalapril as presentation form of Takayasu's arteritis].

    abstract::The case of a 19 year old patient with Takayasu arteritis with exclusive involvement of the abdominal aorta and without involvement of the renal arteries who presented severe arterial hypertension during the acute phase of the disease is referred. The administration of a dose of 20 mg of enalapril maleate was followed...

    journal_title:Medicina clinica

    pub_type: 杂志文章,评审

    doi:

    authors: Górriz JL,Sánchez P,Moll JL,Prieto M,Orero E,Cruz JM

    更新日期:1994-01-22 00:00:00

  • [Effectiveness of aquatic biodance on sleep quality, anxiety and other symptoms in patients with fibromyalgia].

    abstract:BACKGROUND AND OBJECTIVE:To analyze the effects of an aquatic biodance based therapy on sleep quality, anxiety, depression, pain and quality of life in fibromyalgia patients. PATIENTS AND METHOD:Randomized controlled trial with 2 groups. Fifty-nine patients were assigned to 2 groups: experimental group (aquatic biodan...

    journal_title:Medicina clinica

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.medcli.2012.09.036

    authors: López-Rodríguez MM,Fernández-Martínez M,Matarán-Peñarrocha GA,Rodríguez-Ferrer ME,Granados Gámez G,Aguilar Ferrándiz E

    更新日期:2013-12-07 00:00:00

  • [Carbapenem and multidrug-resistant Acinetobacter baumannii colonisation/infection: epidemiology and factors associated with infection].

    abstract:BACKGROUND AND OBJECTIVE:To study an outbreak of nosocomial colonisation/infection due to multidrug and carbapenem resistant A. baumannii (ABMDR-C). PATIENTS AND METHODS:Prospective study of patients with ABMDR-C colonisation/infection (January 2007-June 2008). Epidemiological and clinical variables and predictors of ...

    journal_title:Medicina clinica

    pub_type: 杂志文章

    doi:10.1016/j.medcli.2010.01.033

    authors: Hernández-Torres A,García-Vázquez E,Gómez J,Canteras M,Ruiz J,Fernández-Rufete A,Herreroa JA,Yagüe G

    更新日期:2010-09-18 00:00:00