Abstract：
:Cardiovascular disease is a chronic disorder which is usually already at an advanced stage when the first symptoms develop. The fact that the initial clinical presentation can be lethal or highly incapacitating emphasizes the need for primary and secondary prevention. It is estimated that the ratio of patients with good adherence to secondary prevention of cardiovascular disease is low and also decreases gradually over time. The Polypill for secondary prevention of cardiovascular disease is the first fixed-dose combination therapy of salicylic acid, atorvastatin and ramipril approved in Spain. The purpose of this consensus document was to define and recommend, through the evidence available in the literature and clinical expert opinion, the impact of treatment adherence in the secondary prevention of cardiovascular disease and the use of the Polypill in daily clinical practice as part of a global strategy including adjustments in patient lifestyle. A RAND/UCLA methodology based on scientific evidence, as well as the collective judgment and clinical expertise of an expert panel was used for this assessment. As a result, a final report of recommendations on the impact of the lack of adherence to treatment of secondary prevention of cardiovascular disease and the effect of using a Polypill in adherence of patients was produced. The recommendations included in this document have been addressed to all those specialists, cardiologists, internists and primary care physicians with competence in prescribing and monitoring patients with high and very high cardiovascular risks.
journal_name
Med Clin (Barc)journal_title
Medicina clinicaauthors
González-Juanatey JR,Mostaza JM,Lobos JM,Abarca B,Llisterri JL,Baron-Esquivias G,Galve E,Lidón RM,Garcia-Moll FX,Sánchez PL,Suárez C,Millán J,Pallares V,Alemán JJ,Egocheaga Idoi
10.1016/j.medcli.2016.10.031subject
Has Abstractpub_date
2017-02-09 00:00:00pages
139.e1-139.e15issue
3eissn
0025-7753issn
1578-8989pii
S0025-7753(16)30565-6journal_volume
148pub_type
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