Abstract：
INTRODUCTION AND OBJECTIVES:Dilatation of the ascending aorta associated with bicuspid aortic valve is a major cause of morbidity and mortality in adults. The main objective was to recognize the aortic involvement in children, its characteristics and risk factors. METHODS:Aortic measures of all pediatric patients with bicuspid aortic valve followed in a tertiary pediatric hospital between 1997 and 2015 were retrospectively taken. Patients with syndromes associated with aortic dilatation were excluded (n=17). RESULTS:Two hundred and six patients were included, 67.9% males. The commonest opening pattern was horizontal: 137 (66.7%). Half of the patients (101) had a history of surgical aortic coarctation, 46 (22.3%) had≥moderate aortic valve stenosis and 13 (6%) had≥moderate aortic insufficiency. Mean follow-up time was 6.1 (4.9) years; diagnosis of aortic dilatation was made during the first year of follow-up. Progression of the dilatation of the ascending aorta was noted in 17.1%, and of the aortic root in 2.5%. More than one-third (80/206) had aortic dilatation (z-score>2). The ascending aorta was exclusively affected in 70/80 patients, with sparing of the aortic root. In the multivariate analysis, patients with dilatation of the ascending aorta were associated with absence of coarctation (P=.001) and vertical opening pattern (P=.007). CONCLUSIONS:Pediatric patients with bicuspid aortic valve warrant medical follow-up for the frequent association with valve impairment and/or dilatation of the ascending aorta.
journal_name
Med Clin (Barc)journal_title
Medicina clinicaauthors
Sabaté-Rotés A,Sabidó Sanchez L,Gran Ipiña F,Albert Brotons D,Abella RF,Rosés Noguer Fdoi
10.1016/j.medcli.2017.03.041subject
Has Abstractpub_date
2017-11-09 00:00:00pages
391-396issue
9eissn
0025-7753issn
1578-8989pii
S0025-7753(17)30326-3journal_volume
149pub_type
杂志文章相关文献
MEDICINA CLINICA文献大全abstract：:The authors study the usefulness of the measurement of the negative area of P in V1 (Morris' index) in patients with acute myocardial infarction. The study was carried out prospectively in 70 patients, 31 of them having a Swan-Ganz catheter inserted permitting simultaneous hemodynamic and electrocardiographic measurem...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1981-03-10 00:00:00
abstract：:It is the aim of this manuscript to take into account the peculiarities and specific characteristics of elderly patients with chronic ischaemic heart disease from a multidisciplinary perspective, with the participation of the Spanish Society of Cardiology (sections of Geriatric Cardiology and Ischaemic Heart Disease/A...
journal_title：Medicina clinica
pub_type： 共识发展会议,杂志文章,实务指引
doi：10.1016/j.medcli.2016.01.014
更新日期：2016-04-15 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Since World Health Organization (WHO) recommends brief interventions for smoking cessation to be included systematically in daily practise as a part of clinical work, the main aim of this study is to know if this intervention is done by health professionals working in hospital wards in a genera...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1157/13106128
更新日期：2007-05-19 00:00:00
abstract：BACKGROUND AND OBJECTIVE:There is contradictory evidence as to whether the pleiotropic effects of statins improve morbidity/mortality rates in coronary artery bypass grafting with extracorporeal circulation, as they reduce the protein plasma levels in the acute phase. PATIENTS AND METHOD:This randomized prospective st...
journal_title：Medicina clinica
pub_type： 杂志文章,随机对照试验
doi：10.1157/13121102
更新日期：2008-05-31 00:00:00
abstract：:The association of deep vein thrombosis with systemic necrotizing vasculitis is infrequent. Herein are referred two patients with microscopic polyarteritis and one patient with overlap syndrome who developed deep vein thrombosis which complicated in two cases with pulmonary embolism. The clinical features and the path...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1993-12-11 00:00:00
abstract：BACKGROUND:To determine the nonfulfillment of antiinfectious therapy in clinical practice. MATERIAL AND METHODS:Fulfillment was quantified by tablet counting (TC) in the homes of 366 patients undergoing antibiotic treatment and the motives and predictive factors were identified. RESULTS:Nonfulfillment was of 61% (95%...
journal_title：Medicina clinica
pub_type： 杂志文章,多中心研究
doi：
更新日期：1999-05-29 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Direct oral anticoagulants (DOACs) require dose adjustment according to estimated clearance creatinine (eClCr) using the Cockcroft-Gault (CG) equation. There are discrepancies with the equations that estimate glomerular filtration rate (eGFR). We analyse how the use of the CKD-EPI and MDRD-4 ID...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/j.medcli.2017.06.003
更新日期：2018-02-09 00:00:00
abstract：BACKGROUND:Erythema induratum of Bazin (BEI), is included in the group of cutaneous granulomatous lobulillar panniculitis. The aethiopathogenic association between EI and tuberculosis can not rely on the clinicohistological features of these panniculitis and M. tuberculosis has never been isolated from BEI lesions. Det...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1996-11-30 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Diffuse idiopathic skeletal hyperostosis (DISH) and abdominal aortic calcification (AAC) are related to an increased cardiovascular risk. The aim of this study was to analyse a possible relationship between both entities and also the association between metabolic disorders and DISH. PATIENTS A...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/j.medcli.2017.01.030
更新日期：2017-09-08 00:00:00
abstract：:Fosfosal or 2-phosphonoxybenzoic acid is a new analgesic drug, whose analgesic activity and side effects have been determined in a double blind clinical study in comparison with placebo. The study has been done with 60 outpatients, of both sexes, which suffered musculoskeletal and arthritic pains. Patients were treate...
journal_title：Medicina clinica
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1981-01-10 00:00:00
abstract：BACKGROUND AND OBJECTIVE:An important input to decision-making and health planning is a consistent and comparative description of the population health status. The purpose of this study was to describe the burden of disease in the Region of Valencia (Spain). MATERIAL AND METHODS:Disability-adjusted life years (DALYs) ...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/j.medcli.2012.01.028
更新日期：2013-04-20 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The impact and burden of disease of the rare diseases (RD) is not known, also the type of disability that entail. The objective of the work is to analyze the socio-sanitary impact of the RD in Spain. PATIENTS AND METHOD:This is a nationwide study. The dimensions used were mobility, personal ca...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1157/13112096
更新日期：2007-11-10 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Autoimmune diseases/autoantibodies tend sometimes to cumulate in the same individual, probably as a consequence of defects in immune regulation with breakdown of self-tolerance. Autoimmune hepatitis and microscopic polyangiitis have been occasionally reported with other autoimmune diseases, but...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/j.medcli.2010.10.015
更新日期：2011-03-26 00:00:00
abstract：BACKGROUND:The aim of this study is to assess the prevalence of Parvovirus B19 infection in a group of patients affected by congenital coagulation disorders and its association with epidemiological aspects. PATIENTS AND METHODS:We have analyzed a group of 50 patients (median age 28) diagnosed with haemophilia or any o...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1997-05-03 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Several models for the prediction of liver fibrosis have been developed which consist of the measurement of routine laboratory data: a) a model combining platelets, gamma-glutamil-transpeptidase, cholesterol and age (Forns model), and b) a model using an aspartate-aminotransferase to platelet r...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1157/13075845
更新日期：2005-05-28 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The aims of the present study were to analyze the prognosis after resuscitation from out-of-hospital sudden cardiac death in patients admitted to the coronary care unit, and to identify the predictor variables of morbi-mortality. PATIENTS AND METHOD:From November 1999 to January 2004 we analyz...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/s0025-7753(06)72232-1
更新日期：2006-09-02 00:00:00
abstract：:The electrocardiogram as a diagnostic aid in acute myocardial infarction of the right ventricle (AMI-RV) was studied prospectively in a group of 66 patients in our coronary unit. Diagnosis was AMI in all cases, divided into 29 (44%) with posterior-descending and 35 (53%) with anterior location. Electrocardiography was...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1981-09-25 00:00:00
abstract：BACKGROUND:We describe the cytogenetic results of 93 patients with myelodysplastic syndromes (MDS). The main object of this report is to analyze the prognostic value of the karyotype in patients with MDS, in relation to the evolution to acute leukemia and the survival time. PATIENTS AND METHODS:Cytogenetic studies wer...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1998-01-31 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The association of an exaggerated systolic blood pressure increase with exercise (EBPIE) with cardiovascular events remains controversial. Our aim was to determine the possible association of an EBPIE with survival and risk of serious cardiac events in patients with hypertension and known or su...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/j.medcli.2016.09.016
更新日期：2017-01-20 00:00:00
abstract：:The case of a patient with the diagnosis of essential thrombocythemia is presented. Following treatment with melphalan during three years the patient presented clinical and radiologic data of pulmonary fibrosis. Thoracotomy with lung biopsy histologically proving fibrosis was performed. The patient developed a true hi...
journal_title：Medicina clinica
pub_type： 杂志文章,评审
doi：
更新日期：1993-01-23 00:00:00
abstract：BACKGROUND:In 2001 an outbreak of Legionnaires' diseases occurred in Murcia, Spain, with one of the lowest known rates of associated mortality. We describe the clinical data of a subgroup of patients, and present the results from molecular and virulence studies to correlate the lower mortality of the overall series wit...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/j.medcli.2009.05.016
更新日期：2009-09-12 00:00:00
abstract：:Meningitis and other infectious diseases of the central nervous system are predisposing causes of the inadequate secretion syndrome of the antidiuretic hormone (ISADH). The association between the acquired immunodeficiency syndrome (AIDS) and ISADH is recognized but little studied. In AIDS patients hyponatremia is a f...
journal_title：Medicina clinica
pub_type： 杂志文章,评审
doi：
更新日期：1993-03-20 00:00:00
abstract：:The health information system in Catalonia has experienced an important evolution but obtaining integrated data to evaluate the health services is still difficult. At the end of 2008 the basis of the information system of the "Center of Results" and a first set of indicators has been approved by the health system stak...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/S0025-7753(10)70006-3
更新日期：2010-02-01 00:00:00
abstract：:Diabetic dyslipidemia, characterized by the lipid triad (elevated plasma triglycerides, low HDL cholesterol and predominance of small, dense LDL particles), is a significant contributor to the elevated cardiovascular risk of type 2 diabetic patients. Statin monotherapy has shown, in different prospective trials, signi...
journal_title：Medicina clinica
pub_type： 杂志文章,评审
doi：10.1016/j.medcli.2009.10.010
更新日期：2010-04-03 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The aim of this study was to describe the evolution of serologically confirmed cases of mumps in the Madrid Community from 2000 to 2006. PATIENTS AND METHOD:Cases with data about age, sex and with samples obtained < or = 30 days after the onset of symptoms were included. IgM determination was ...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1157/13116573
更新日期：2008-03-08 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The proportion of elderly patients hospitalized in acute care wards has progressively increased. Patients with a decreased functional status are prone to have malnutrition which negatively affects their prognosis and increases mortality. However, it is unclear whether functional and nutritional...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1016/s0025-7753(04)74521-2
更新日期：2004-09-25 00:00:00
abstract：:A prospective clinical and electrophysiologic study was performed in 50 alcoholic patients in order to assess the incidence and clinical manifestations of alcoholic polyneuropathy, the value of the electrophysiologic parameters studied, and the influence of liver disease on the appearance of neuropathy. The proposed c...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1981-03-10 00:00:00
abstract：:Atherosclerotic renovascular disease is a common entity, particularly in persons older than 50 years of age and especially in those patients with other evidence of atherosclerotic vascular disease. The illness clearly progresses in some patients, and progression rate appears to be highly variable. Taken into account t...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1997-04-12 00:00:00
abstract：BACKGROUND:Human immunodeficiency virus (HIV) increases the risk for anal premalignant lesions associated to human papillomavirus infection (HPV). The aim of this study was to compare the prevalence of HPV and squamous intraepithelial lesions (SIL) in patients with anal warts, with and without anti-HIV antibodies. PAT...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：
更新日期：1999-06-12 00:00:00
abstract：BACKGROUND AND OBJECTIVE:To determine whether in the Mexican population the spouses of patients with type 2 diabetes mellitus (DM2) have an increased risk of any degree of glucose intolerance compared with spouses of subjects without diabetes. SUBJECTS AND METHOD:An analytical cross-sectional study was made in the Fam...
journal_title：Medicina clinica
pub_type： 杂志文章
doi：10.1157/13127917
更新日期：2008-11-08 00:00:00
