Abstract:
BACKGROUND AND OBJECTIVE:The aims of the present study were to analyze the prognosis after resuscitation from out-of-hospital sudden cardiac death in patients admitted to the coronary care unit, and to identify the predictor variables of morbi-mortality. PATIENTS AND METHOD:From November 1999 to January 2004 we analyzed 63 patients (47 males) aged 61 +/- 12 years who were admitted to the coronary care unit following successful resuscitation from sudden cardiac death. The clinical and electrocardiographic characteristics were correlated with the mortality and neurological impairment. RESULTS:Thirty-five patients (55.5%) were discharged, while twenty-eight patients (45.5%) died 28 +/- 4 days after admission, most of them during hospitalization. The main underlying disorder was coronary artery disease (80.9%). When survivors and non-survivors were compared, the variables associated with a worse prognosis were diabetes mellitus (68.4% vs 17.1%, P < .02), the presence of valvular heart disease (28.6% vs 0%, p < 0.003), chronic atrial fibrillation (42.9% vs 14.3%, P < .02) and asystole as the initial rhythm observed (42.9% vs 11.4%, P < .01). Multivariate analysis identified asystole as an independent factor of poor prognosis (P < .02). Death was due to severe postanoxic neurological damage in 23 of 28 deaths (82.1%). The remaining 5 patients died due to their underlying cardiac disease (P < .01). The variables associated with neurological damage were out-of hospital resuscitation, delay in beginning resuscitation maneuvers, arrival time > 5 minutes and unconsciousness on admission. CONCLUSIONS:Although many patients survive following resuscitation from out-of-hospital sudden cardiac death, mortality remains high. Neurological impairment is the main cause of mortality. Prognosis is determined by the variables related to the underlying disease, the delay in onset of resuscitation maneuvers and postanoxia cerebral damage.
journal_name
Med Clin (Barc)journal_title
Medicina clinicaauthors
Vallès E,Martí V,Noguero M,Guindo J,Domínguez de Rozas JMdoi
10.1016/s0025-7753(06)72232-1subject
Has Abstractpub_date
2006-09-02 00:00:00pages
281-5issue
8eissn
0025-7753issn
1578-8989pii
S0025-7753(06)72232-1journal_volume
127pub_type
杂志文章相关文献
MEDICINA CLINICA文献大全abstract:BACKGROUND:Hypertension and dyslipemia are associated with a greater frequency than that randomly expected. The increase in insulinic resistance hyperinsulinemia is one of the factors implicated in the pathogenesis of this association. In the present study the lipid profile of hypertensive patients is analyzed accordin...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1994-09-10 00:00:00
abstract::A case of rapidly progressive glomerular disease with 100% of epithelial crescents completely enveloping each glomerulus, prolonged anuria and renal failure requiring dialysis. There were no indications of either streptococcal etiology or systemic disease. Improvement in renal function in response to plasmapheresis an...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1981-06-10 00:00:00
abstract::The case of a patient with the diagnosis of essential thrombocythemia is presented. Following treatment with melphalan during three years the patient presented clinical and radiologic data of pulmonary fibrosis. Thoracotomy with lung biopsy histologically proving fibrosis was performed. The patient developed a true hi...
journal_title:Medicina clinica
pub_type: 杂志文章,评审
doi:
更新日期:1993-01-23 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Our goal was to analyze the epidemiological and clinical findings, as well as the diagnostic approach in a group of patients in whom uveitis was the first manifestation of sarcoidosis. PATIENTS AND METHOD:Retrospective study (between March 1998 and July 2002) including 31 patients diagnosed wi...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/s0025-7753(04)74374-2
更新日期:2004-05-22 00:00:00
abstract:BACKGROUND:A different epidemiologic pattern of the neoplasms associated to the human immunodeficiency virus (HIV) has been described in the Mediterranean area. The aim of the present study was to analyze the epidemiologic, clinical and evolutive characteristics of these patients. METHODS:A retrospective study of 74 n...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1993-05-15 00:00:00
abstract:INTRODUCTION AND OBJECTIVE:Epicardial fat has been associated with increased cardiovascular risk and the development of atherosclerosis. Transthoracic echocardiography provides a reliable measurement of epicardial fat thickness (EFT). The aim of this study is to evaluate the relationship between EFT and biochemical par...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2018.01.019
更新日期:2018-09-21 00:00:00
abstract:BACKGROUND:Outbreaks of nosocomial infection by methicillin resistent Staphylococcus aureus (MRSA) are a problem in many hospitals with the control measures to be adopted being controversial. An outbreak of MRSA in a 550-bed university hospital is herein described and the impact of the adopted control measures on the e...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1997-03-22 00:00:00
abstract:BACKGROUND AND OBJECTIVE:White coat effect (WCE) (i.e., the difference between office blood pressure [OBP] and awake ambulatory blood pressure monitoring [ABPM]) may be present in hypertensive individuals. The relationship between occurrence of WCE and target organ damage (TOD) has not yet been assessed in true resista...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2012.04.031
更新日期:2013-01-05 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Diffuse idiopathic skeletal hyperostosis (DISH) and abdominal aortic calcification (AAC) are related to an increased cardiovascular risk. The aim of this study was to analyse a possible relationship between both entities and also the association between metabolic disorders and DISH. PATIENTS A...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2017.01.030
更新日期:2017-09-08 00:00:00
abstract:BACKGROUND AND OBJECTIVE:There is contradictory evidence as to whether the pleiotropic effects of statins improve morbidity/mortality rates in coronary artery bypass grafting with extracorporeal circulation, as they reduce the protein plasma levels in the acute phase. PATIENTS AND METHOD:This randomized prospective st...
journal_title:Medicina clinica
pub_type: 杂志文章,随机对照试验
doi:10.1157/13121102
更新日期:2008-05-31 00:00:00
abstract:BACKGROUND AND OBJECTIVE:This study was aimed to verify whether it is possible to detect at hospital admission, by means of INTERMED, pneumonology patients at risk of "complexity" and of specialized psychosocial intervention. PATIENTS AND METHOD:With the Spanish version of INTERMED (for detection of risk for complexit...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/s0025-7753(08)75487-3
更新日期:2008-11-29 00:00:00
abstract::The ANESCAT 2003 survey has provided reliable information on all practices within the specialty of anesthesiology in a community comprising 6.7 million inhabitants (namely Catalonia, Spain). In a situation in which official statistics are lacking, the findings allow us to make predictions and plan the clinical and org...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1157/13088807
更新日期:2006-05-24 00:00:00
abstract:BACKGROUND:To check the possible usefulness in studying DNA in dried blood spots taken on filter paper blotters for newborn identification. It set out to establish: 1. The validity of the method for analysis; 2. The validity of all stored samples (such as those kept in clinical records); 3. Guarantee of non-intrusion i...
journal_title:Medicina clinica
pub_type: 临床试验,杂志文章
doi:
更新日期:1996-06-22 00:00:00
abstract:BACKGROUND:Cytogenetic studies of meningiomas suggest that loss of (or parts of) chromosome 22 is a primary event in the development of these tumors; later on, other chromosomal changes would occur in the caryotypes. All these secondary changes are observed mainly in cases with high clinical aggressivity. However, in a...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1998-11-21 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Burden of disease (DALYs) can help define health priorities. Our objective was to assess DALYs of those illnesses most important in Spanish children and teenagers. MATERIAL AND METHOD:We calculated DALYs components (YLL, YLD) by age groups and sex. Sources used were Spanish mortality data and ...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/s0025-7753(04)74245-1
更新日期:2004-03-20 00:00:00
abstract:BACKGROUND AND OBJECTIVE:To assess the usefulness of a risk scale based on serum procalcitonin (PCT) compared to the Laboratory Risk Indicator for Necrotising Fasciitis (LRINEC) scale in the early discrimination between necrotising fasciitis (NF) and cellulitis of the extremities. MATERIALS AND METHODS:Retrospective s...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/j.medcli.2019.01.032
更新日期:2019-11-15 00:00:00
abstract:BACKGROUND:The administration of factor VIII (FVIII) in continuous infusion (CI) to hemophiliac inpatients is a therapeutic approach made possible by the development of new commercial preparations. METHODS:In the present study the outcome of 14 treatment courses of FVIII in CI to 12 patients with hemophilia A (2 of th...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1991-03-16 00:00:00
abstract:OBJECTIVE:In December 2019, Wuhan, China, experienced an outbreak of coronavirus disease 2019 (COVID-19). Some patients admitted to our hospital were treated with early prone positioning (PP). Here, we analyzed its clinical significance. METHODS:This was a retrospective observational study. We defined the early PP gro...
journal_title:Medicina clinica
pub_type:
doi:10.1016/j.medcli.2020.11.036
更新日期:2020-12-26 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Forced respiratory volume in first second spirometry is currently used to diagnose chronic obstructive pulmonary disease. However, this technique does not always provide a reliable short-term prognosis, especially in patients with associated morbidity. We propose that specific health-related qu...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1157/13058683
更新日期:2004-03-06 00:00:00
abstract::The aging of the population and changes in family and social structures have led to increasing care needs for elderly persons following an acute disease or accident, with consequent concerns regarding costs and sustainability within the public health system. The main objective of postacute care (PAC) is to restore the...
journal_title:Medicina clinica
pub_type: 杂志文章,评审
doi:10.1016/j.medcli.2013.05.032
更新日期:2014-07-07 00:00:00
abstract::Multiple sclerosis occurs in genetically susceptible individuals, in whom an unknown environmental factor triggers an immune response, giving rise to a chronic and disabling autoimmune disease. Currently, significant progress is being made in our knowledge of the frequency and distribution of multiple sclerosis and it...
journal_title:Medicina clinica
pub_type: 杂志文章,评审
doi:10.1016/S0025-7753(15)30010-5
更新日期:2014-12-01 00:00:00
abstract:BACKGROUND:A high prevalence of osteoporosis has been described in patients before and after cardiac transplantation. But clinical factors involved in previous bone loss in this condition are not well known. The purpose has been to study bone mineral density (BMD) in patients subject to cardiac transplantation, analyzi...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/s0025-7753(00)71430-8
更新日期:2000-05-27 00:00:00
abstract:BACKGROUND:The evaluation of the costs of intensive care is a subject of interest at present, due to the high resources required by this area of health care services and the rhythm at which these costs increase. Such an evaluation has rarely been carried out in Spain. The aim of this study was to quantify the cost of m...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1994-06-11 00:00:00
abstract:BACKGROUND:Exercise tests has been used in the diagnosis of metabolic myopathies. If there is an abnormal response pattern in mild mitochondrial myopathy (MM) and her role in the initial suspect diagnostic is unknown. SUBJECTS AND METHODS:Prospective study of 26 patients with mitochondrial myopathy (15 men, 11 women) ...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/s0025-7753(00)71216-4
更新日期:2000-02-05 00:00:00
abstract::Community-acquired pneumonia (CAP) is an infectious respiratory disease with an incidence that ranges from 3 to 8 cases per 1,000 inhabitants per year. This incidence increases with age and comorbidities. Forty per cent of CAP patients require hospitalization and around 10% of these patients are admitted in an Intensi...
journal_title:Medicina clinica
pub_type: 共识发展会议,杂志文章,实务指引
doi:10.1016/j.medcli.2012.09.034
更新日期:2013-03-02 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Parkinsonism is a group of neurological disorders characterized by extrapiramidal signs. Often, the differential diagnosis between parkinsonism, essential tremor and drug-induced parkinsonism is difficult. The aim of the study was to evaluate the utility of (123I)-FP-CIT SPECT in patients with ...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/s0025-7753(04)74224-4
更新日期:2004-03-13 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Due to recent medical advances, patients with cystic fibrosis (CF) can expect longer survival rates and, as a result, face previously unreported complications such as osteoporosis. Our goal was to determine the mineral bone density in young adult patients with CF attended in the adult CF Unit, ...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:10.1016/s0025-7753(04)74420-6
更新日期:2004-06-19 00:00:00
abstract::The usefulness of two alpha-2 adrenergic agonists (clonidine and guanfacine) and their comparative effectiveness were evaluated regarding the control of the opiates abstinence syndrome and the secondary effects, including development of cardiovascular abnormalities, in 88 parenteral heroin abusers admitted to two hosp...
journal_title:Medicina clinica
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1990-02-10 00:00:00
abstract:BACKGROUND AND OBJECTIVE:The treatment of biliary tract infections requires antibiotics and an appropriate surgical procedure. The aim of this study was to evaluate the efficacy and safety of piperacillin/tazobactam versus ceftriaxone plus ornidazole in the treatment of biliary tract infections. PATIENTS AND METHOD:Th...
journal_title:Medicina clinica
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2003-12-06 00:00:00
abstract::The existence of an increasing number of apparently healthy carriers of the HBsAg demands a specific assisting attitude which must be highly reliable without increasing health care expenses. With that purpose, 129 asymptomatic carriers without prior history of jaundice and/or alcohol abuse were studied. The following ...
journal_title:Medicina clinica
pub_type: 杂志文章
doi:
更新日期:1981-02-25 00:00:00