Correlation between epicardial fat thickness and biochemical markers of metabolic risk.

Abstract:

INTRODUCTION AND OBJECTIVE:Epicardial fat has been associated with increased cardiovascular risk and the development of atherosclerosis. Transthoracic echocardiography provides a reliable measurement of epicardial fat thickness (EFT). The aim of this study is to evaluate the relationship between EFT and biochemical parameters of metabolic risk. MATERIAL AND METHOD:We assessed 211 patients who underwent echocardiography; EFT was measured by two cardiologists. In addition, patients' glycaemia, lipid profile and serum uric acid were measured. Statistical analysis was performed with the Pearson coefficient test and Odds ratio. RESULTS:A positive correlation between EFT with glycaemia (r=.064), total serum cholesterol (r=.0056), high density lipoproteins (r=-.038), or with triglycerides (r=.118) was not observed. However, we did find a significant positive correlation between EFT and serum uric acid (r=.415, P<.00001). The odds ratio for EFT>3mm in patients with hyperuricemia was 6.26 (IC 95 2.79-14, P<.0001). CONCLUSION:Hyperuricemia is strongly associated with EFT in Mexican patients; EFT is a useful tool for global cardiovascular risk calculation.

journal_name

Med Clin (Barc)

journal_title

Medicina clinica

authors

Rubio-Guerra AF,Benítez-Maldonado DR,Lozano-Nuevo JJ,Arana-Pazos KC,Huerta-Ramirez S,Narváez-Rivera JL

doi

10.1016/j.medcli.2018.01.019

subject

Has Abstract

pub_date

2018-09-21 00:00:00

pages

236-238

issue

6

eissn

0025-7753

issn

1578-8989

pii

S0025-7753(18)30068-X

journal_volume

151

pub_type

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